Connectome-Specific Harmonic Waves on LSD

The harmonics-in-connectome approach to modeling brain activity is a fascinating paradigm. I am privileged to have been at this talk in the 2017 Psychedelic Science conference. I’m extremely happy find out that MAPS already uploaded the talks. Dive in!

Below is a partial transcript of the talk. I figured that I should get it in written form in order to be able to reference it in future articles. Enjoy!

[After a brief introduction about harmonic waves in many different kinds of systems… at 7:04, Selen Atasoy]:

We applied the [principle of harmonic decomposition] to the anatomy of the brain. We made them connectome-specific. So first of all, what do I mean by the human connectome? Today thanks to the recent developments in structural neuroimaging techniques such as diffusion tensor imaging, we can trace the long-distance white matter connections in the brain. These long-distance white matter fibers (as you see in the image) connect distant parts of the brain, distant parts of the cortex. And the set of all of the different connections is called the connectome.

selen_connectome_image

Now, because we know the equation governing these harmonic waves, we can extend this principle to the human brain by simply solving the same equation on the human connectome instead of a metal plate (Chladni plates) or the anatomy of the zebra. And if you do that, we get a set of harmonic patterns, this time emerging in the cortex. And we decided to call these harmonic patterns connectome harmincs. And each of these connectome harmonic patterns are associated with a different frequency. And because they correspond to different frequencies they are all independent, and together they give you a new language, so to speak, to describe neural activity. So in the same way the harmonic patterns are building blocks of these complex patterns we see on animal coats, these connectome harmonics are the building blocks of the complex spatio-temporal patterns of neural activity.

Describing and explaining neural activity by using these connectome harmonics as brain states is really not very different than decomposing a complex musical pieces into its musical notes. It’s simply a new way of representing your data, or a new language to express it.

What is the advantage of using this new language? So why not use the state-of-the-art conventional neurimaging analysis methods? Because these connectome harmonics, by definition are the vibration modes, but applied to the anatomy of the human brain, and if you use them as brain states to express neural activity we can compute certain fundamental principles very easily such as the energy or the power.

The power would be the strength of activation of each of these states in neural activity. So how strongly that particular state contributes to neural activity. And the energy would be a combination of this strength of activation with the intrinsic energy of that particular brain state, and the intrinsic energy comes from the frequency of its vibration (in the analogy of vibration).

So in this study we looked at the power and the energy of these connectome harmonic brain states in order to explore the neural correlates of the LSD experience.

We looked at 12 healthy participants who received either 75µg of LSD (IV) or a placebo, over two sessions. These two sessions were 14 days apart in counter-balanced order. And the fMRI scans consisted of 3 eyes-closed resting states scans, each lasting 7 minutes, in the first and the third scan the participants were simply resting, eyes closed, but in the second scan they were also listening to music. And after each scan, the participants rated the intensity of certain experiences.

activity_power_energy_scans.png

So if you look at, firstly, at the total power and the total energy of each of these scans under LSD and placebo, what we see is that under LSD both the power as well as the energy of brain activity increases significantly.

And if we compute the probability of observing a certain energy value on LSD or placebo, what we see is that the peak of this probability distribution clearly shoots towards high energy values under LSD.

energy_difference

And that peak is even slightly higher in terms of probability when the subjects were listening to music. So if we interpret that peak as, in a way, the characteristic energy of a state, you can see that it shifts towards higher energy under LSD, and that this effect is intensified when listening to music.

And then we asked, which of these brain states, which of these frequencies, were actually contributing to this energy increase. So we partitioned the spectrum of all of these harmonic brain states into different parts and computed the energy of each of these partitions individually. So in total we have around 20,000 brain states. And if you look at the energy differences in LSD and placebo, what we find is that for a very narrow range of low frequencies actually these brain states were decreasing their energy on LSD. But for a very broad range of high frequencies, LSD was inducing an energy increase. So this says that LSD alters brain dynamics in a very frequency-selective manner. And it was causing high frequencies to increase their energy.

So next we looked at whether these changes we are observing in brain activity are correlated with any of the experiences that the participants themselves were having in that moment. If you look at the energy changes within the narrow range of low frequencies, we found that the energy changes in that range significantly correlated with the intensity of the experience of ego dissolution. The loss of subjective self.

ego_dissolution

And very interestingly, the same range of energy change within the same frequency range also significantly correlated with the intensity of emotional arousal, whether the experience was positive or negative. This could be quite relevant for studies looking into potential therapeutic applications of LSD.

emotional_arousal

Next, when we look at a slightly higher range of frequencies, what we found was that the energy changes within that range significantly correlated with the positive mood.

higher_frequencies

In brief, this suggests that it’s rather the low frequency brain states which correlated with ego dissolution or with emotional arousal, and it’s the activity of higher frequencies that is correlated with the positive experiences.

Next, we wanted to check the size of the repertoire of active brain states. And if you look at the probability of activation for any brain state (so we are not distinguishing for any frequency brain states), what we observe is that the probability of a brain state being silent (zero contribution), actually decreased under LSD. And the probability of a brain state contributing very strongly, which corresponds to the tails of these distributions, were increased under LSD. So this suggests that LSD was activating more brain states simultaneously.

repertoaire

And if we go back to the music analogy that we used in the beginning, that would correspond to playing more musical notes at the same time. And it’s very interesting, because studies that have looked at improvising, those who have looked at jazz improvisation, show that improvising jazz musicians play significantly more musical notes compared to memorized play. And this is what we seem to be finding under the effect of LSD. That your brain is actually activating more of these brain states simultaneously.

cross-frequency

And it does so in a very non-random fashion. So if you look at the correlation across different frequencies. Like at the co-activation patterns, and their activation over time. You may interpret it as the “communication across various frequencies”. What we found is that for a very broad range of the spectrum, there was a higher correlation across different frequencies in their activation patterns under LSD compared to placebo.

So this really says that LSD is actually causing a reorganization, rather than a random activation of brain states. It’s expanding the repertoire of active brain states, while maintaining -or maybe better said- recreating a complex but spontaneous order. And in the musical analogy it’s really very similar to jazz improvisation, to think about it in an intuitive way.

Now, there is actually one particular situation when dynamical systems such as the brain, and systems that change their activity over time, show this type of emergence of complex order, or enhanced improvisation, enhanced repertoire of active states. And this is when they approach what is called criticality. Now, criticality is this special type of behavior, special type of dynamics, that emerges right at the transition between order and chaos. When these two (extreme) types of dynamics are in balance. And criticality is said to be “the constantly shifting battle zone between stagnation and anarchy. The one place where a complex system can be spontaneous, adaptive, and alive” (Waldrop 1992). So if a system is approaching criticality, there are very characteristic signatures that you would observed in the data, in the relationships that you plot in your data.

And one of them is -and probably the most characteristic of them- is the emergence of power laws. So what does that mean? If you plot one observable in our data, which for example, in our case would be the maximum power of a brain state, in relationship to another observable, for example, the wavenumber, or the frequency of that brain state, and you plot them in logarithmic coordinates, that would mean that if they follow power laws, they would approximate a line. And this is exactly what we observe in our data, and surprisingly for both LSD as well as for placebo, but with one very significant and remarkable difference: because the high frequencies increase their power on LSD, this distribution follows this power law, this line, way more accurately under LSD compared to placebo. And here you see the error of the fit, which is decreasing.

This suggests that LSD shoots brain dynamics further towards criticality.  The signature of criticality that we find in LSD and in placebo is way more enhanced, way more pronounced, under the effect of LSD. And we found the same effect, not only for the maximum power, but also for the mean power, as well as for the power of fluctuations.

criticality_signature

So this suggests that the criticality actually may be the principle that is underlying this emergence of complex order, and this reorganization of brain dynamics, and which leads to enhanced improvisation in brain activity.

So, to summarize briefly, what we found was that LSD increases the total power as well as total energy of brain activity. It selectively activates high frequency brain states, and it expands the repertoire or active brain states in a very non-random fashion. And the principle underlying all of these changes seems to be a reorganization of brain dynamics, right at criticality, right at the edge of chaos, or just as the balance between order and chaos. And very interestingly, the “edge of chaos”, or the edge of criticality, is said to be where “life has enough stability to sustain itself, and enough creativity to deserve the name of life” (Waldrop 1992). So I leave you with that, and thank you for your attention.

[Applauses; ends at 22:00, followed by Q&A]

ELI5 “The Hyperbolic Geometry of DMT Experiences”

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I wrote the following in response to a comment on the r/RationalPsychonaut subreddit about this DMT article I wrote some time ago. The comment in question was: “Can somebody eli5 [explain like I am 5 years old] this for me?” So here is my attempt (more like “eli12”, but anyways):

In order to explain the core idea of the article I need to convey the main takeaways of the following four things:

  1. Differential geometry,
  2. How it relates to symmetry,
  3. How it applies to experience, and
  4. How the effects of DMT turn out to be explained (in part) by changes in the curvature of one’s experience of space (what we call “phenomenal space”).

1) Differential Geometry

If you are an ant on a ball, it may seem like you live on a “flat surface”. However, let’s imagine you do the following: You advance one centimeter in one direction, you turn 90 degrees and walk another centimeter, turn 90 degrees again and advance yet another centimeter. Logically, you just “traced three edges of a square” so you cannot be in the same place from which you departed. But let’s says that you somehow do happen to arrive at the same place. What happened? Well, it turns out the world in which you are walking is not quite flat! It’s very flat from your point of view, but overall it is a sphere! So you ARE able to walk along a triangle that happens to have three 90 degree corners.

That’s what we call a “positively curved space”. There the angles of triangles add up to more than 180 degrees. In flat spaces they add up to 180. And in “negatively curved spaces” (i.e. “negative Gaussian curvature” as talked about in the article) they add up to less than 180 degrees.

oct

Eight 90-degree triangles on the surface of a sphere

So let’s go back to the ant again. Now imagine that you are walking on some surface that, again, looks flat from your restricted point of view. You walk one centimeter, then turn 90 degrees, then walk another, turn 90 degrees, etc. for a total of, say, 5 times. And somehow you arrive at the same point! So now you traced a pentagon with 90 degree corners. How is that possible? The answer is that you are now in a “negatively curved space”, a kind of surface that in mathematics is called “hyperbolic”. Of course it sounds impossible that this could happen in real life. But the truth is that there are many hyperbolic surfaces that you can encounter in your daily life. Just to give an example, kale is a highly hyperbolic 2D surface (“H2” for short). It’s crumbly and very curved. So an ant might actually be able to walk along a regular pentagon with 90-degree corners if it’s walking on kale (cf. Too Many Triangles).

kale

An ant walking on kale may infer that the world is an H2 space.

In brief, hyperbolic geometry is the study of spaces that have this quality of negative curvature. Now, how is this related to symmetry?

2) How it relates to symmetry

As mentioned, on the surface of a sphere you can find triangles with 90 degree corners. In fact, you can partition the surface of a sphere into 8 regular triangles, each with 90 degree corners. Now, there are also other ways of partitioning the surface of a sphere with regular shapes (“regular” in the sense that every edge has the same length, and every corner has the same angle). But the number of ways to do it is not infinite. After all, there’s only a handful of regular polyhedra (which, when “inflated”, are equivalent to the ways of partitioning the surface of a sphere in regular ways).

Weinberg-1-102711_jpg_630x171_crop_q85

If you instead want to partition a plane in a regular way with geometric shapes, you don’t have many options. You can partition it using triangles, squares, and hexagons. And in all of those cases, the angles on each of the vertices will add up to 360 degrees (e.g. six triangles, four squares, or thee corners of hexagons meeting at a point). I won’t get into Wallpaper groups, but suffice it to say that there are also a limited number of ways of breaking down a flat surface using symmetry elements (such as reflections, rotations, etc.).

tiling2

Regular tilings of 2D flat space

Hyperbolic 2D surfaces can be partitioned in regular ways in an infinite number of ways! This is because we no longer have the constraints imposed by flat (or spherical) geometries where the angles of shapes must add up to a certain number of degrees. As mentioned, in hyperbolic surfaces the corners of triangles add up to less than 180 degrees, so you can fit more than 6 corners of equilateral triangles at one point (and depending on the curvature of the space, you can fit up to an infinite number of them). Likewise, you can tessellate the entire hyperbolic plane with heptagons.

61b801a08a7ef2780e96e0a574b82136

Hyperbolic tiling: Each of the heptagons is just as big (i.e. this is a projection of the real thing)

On the flip side, if you see a regular partitioning of a surface, you can infer what its curvature is! For example, if you see that a surface is entirely covered with heptagons, three on each of the corners, you can be sure that you are seeing a hyperbolic surface. And if you see a surface covered with triangles such that there are only four triangles on each joint, then you know you are seeing a spherical surface. So if you train yourself to notice and count these properties in regular patterns, you will indirectly also be able to determine whether the patterns inhabit a spherical, flat, or hyperbolic space!

3) How it applies to experience

How does this apply to experience? Well, in sober states of consciousness one is usually restricted to seeing and imagining spherical and flat surfaces (and their corresponding symmetric partitions). One can of course look at a piece of kale and think “wow, that’s a hyperbolic surface” but what is impossible to do is to see it “as if it were flat”. One can only see hyperbolic surfaces as projections (i.e. where we make regular shapes look irregular so that they can fit on a flat surface) or we end up contorting the surface in a crumbly fashion in order to fit it in our flat experiential space. (Note: even sober phenomenal space happens to be based on projective geometry; but let’s not go there for now.)

4) DMT: Hyperbolizing Phenomenal Space

In psychedelic states it is common to experience whatever one looks at (or, with more stunning effects, whatever one hallucinates in a sensorially-deprived environment such as a flotation tank) as slowly becoming more and more symmetric. Symmetrical patterns are attractors in psychedelia. It’s common for people to describe their acid experiences as “a kaleidoscope of colors and meaning”. We should not be too quick to dismiss these descriptions as purely metaphorical. As you can see from the article Algorithmic Reduction of Psychedelic States as well as PsychonautWiki’s Symmetrical Texture Repetition, LSD and other psychedelics do in fact “symmetrify” the textures you experience!

8697209364_91f2ab133e_h

What gravel might look like on 150 mics of LSD (Source)

As it turns out, this symmetrification process (what we call “lowering the symmetry detection/propagation threshold”) does allow one to experience any of the possible ways of breaking down spherical and flat surfaces in regular ways (in addition to also enabling the experience of any wallpaper group!). Thus the surfaces of the objects one hallucinates on LSD (specially for Closed Eyes Visuals), are usually carpeted with patterns that have either spherical or flat symmetries (e.g. seeing honeycombs, square grids, regular triangulations, etc.; or seeing dodecahedra, cubes, etc.).

wade_symmetry_best_blank_2

17 wallpaper symmetry groups

Only on very high doses of classic psychedelics does one start to experience objects that have hyperbolic curvature. And this is where DMT becomes very relevant. Vaping it is one of the most efficient ways of achieving “unworldly levels of psychedelia”:

On DMT the “symmetry detection threshold” is reduced to such an extent that any surface you look at very quickly gets super-saturated with regular patterns. Since (for reasons we don’t understand) our brain tries to incorporate whatever shape you hallucinate into the scene as part of the scene, the result of seeing too many triangles (or heptagons, or whatever) is that your brain will “push them into the surfaces” and, in effect, turn those surfaces into hyperbolic spaces.HeptagonsIndrasPearls

Yet another part of your brain (or system of consciousness, whatever it turns out to be) recognizes that “wait, this is waaaay too curved somehow, let me try to shape it into something that could actually exist in my universe”. Hence, in practice, if you take between 10 and 20 mg of DMT, the hyperbolic surfaces you see will become bent and contorted (similar to the pictures you find in the article) just so that they can be “embedded” (a term that roughly means “to fit some object into a space without distorting its properties too much”) into your experience of the space around you.

But then there’s a critical point at which this is no longer possible: Even the most contorted embeddings of the hyperbolic surfaces you experience cannot fit any longer in your normal experience of space on doses above 20 mg, so your mind has no other choice but to change the curvature of the 3D space around you! Thus when you go from “very high on DMT” to “super high on DMT” it feels like you are traveling to an entirely new dimension, where the objects you experience do not fit any longer into the normal world of human experience. They exist in H3 (hyperbolic 3D space). And this is in part why it is so extremely difficult to convey the subjective quality of these experiences. One needs to invoke mathematical notions that are unfamiliar to most people; and even then, when they do understand the math, the raw feeling of changing the damn geometry of your experience is still a lot weirder than you could ever anticipate.

hexagon_sphere_plane_hyp_032

Anybody else want to play hyperbolic soccer? Humans vs. Entities, the match of the eon!

Note: The original article goes into more depth

Now that you understand the gist of the original article, I encourage you to take a closer look at it, as it includes content that I didn’t touch in this ELI5 (or 12) summary. It provides a granular description of the 6 levels of DMT experience (Threshold, Chrysanthemum, Magic Eye, Waiting Room, Breakthrough, and Amnesia), many pictures to illustrate the various levels as well as the particular emergent geometries, and a theoretical discussion of the various algorithmic reductions that might explain how the hyperbolization of phenomenal space takes place based on combining a series of simpler effects together.

Qualia Computing at Consciousness Hacking (June 7th 2017)

I am delighted to announce that I will be presenting at Consciousness Hacking in San Francisco on 2017/6/7 (YMD notation).

Consciousness Hacking (CoHack) is an extremely awesome community that blends a genuine interest in benevolence, scientific rationality, experiential spirituality, self-experimentation, and holistic wellbeing together with an unceasing focus on consciousness. Truth be told, CohHack is one of the reasons why I love living in the Bay Area.

Here are the relevant event links: Eventbrite, FacebookMeetup.

And the event description:


What would happen if a bliss technology capable of inducing a constant MDMA-like state of consciousness with no negative side effects were available? What makes an experience good or bad? Is happiness a spiritual trick, or is spirituality a happiness trick?

At this month’s speaker presentation, Consciousness Hacking invites Data Science Engineer, Andrés Gómez Emilsson to discuss current research, including his own, concerning the measurement of bliss, how blissful brain states can be induced, and what implications this may have on quality of life and our relationship with the world around us.

Emilsson’s research aims to create a mathematical theory of the pleasure-pain axis that can take information about a person’s brain at a given point in time and return the approximate (or even true) level of happiness and suffering for that person. Emilsson will explore two dimensions that have been studied in affective neuroscience for decades:

  • Arousal: how much energy and activation a given emotion has
  • Valence: the “feel good or feel bad” dimension of emotion

If the purpose of life is to feel happy and to make others happy, then figuring out how valence is implemented in the brain may take us a long way in that direction. Current approaches to valence, while helpful, usually don’t address the core of the problem (ie. usually just measuring the symptoms of pleasure such as the neurotransmitters that trigger it, brain regions, positive reinforcement, etc. rather than getting at the experience of pleasure itself).

A real science of valence would not only be able to integrate and explain why the things people report as pleasurable are pleasant, it would also make a precise, empirically falsifiable hypothesis about whether arbitrary brain states will feel good or bad. This is what Emilsson aims to do.

You will take away:

  • An understanding about the current scientific consensus on the nature of happiness in the brain, and why it is incomplete
  • A philosophical case for both the feasibility and desirability of a world devoid of intense suffering
  • A new candidate mathematical formula that can be used to predict the psychological wellbeing of a brain at a given point in time
  • An argument for why bliss technology that puts us in a constant MDMA-like state of consciousness with no negative side effects is likely to become available within the next two to five decades
  • The opportunity to network with other people who are serious about figuring out the meaning of life through introspection and neuroscience

About our speaker:

Andrés Gómez Emilsson was born in México City in 1990. From an early age, he developed an interest in philosophy, mathematics, and science, leading him to compete nationally and internationally in Math and Science Olympiads. At 16, his main interest was mathematics, but after an unexpected “mystical experience”, he turned his attention to consciousness and the philosophical problems that it poses. He studied Symbolic Systems with an Artificial Intelligence concentration at Stanford, and later finished a masters in Computational Psychology at the same university. During his time at Stanford he co-founded the Stanford Transhumanist Association and became good friends with transhumanist philosopher David Pearce, taking on the flag of the Hedonistic Imperative (HI). In order to pursue the long-term goals of HI, his current primary intellectual interest is to reverse-engineer the functional, biochemical and/or quantum signatures of pure bliss.

He is currently working at a Natural Language Processing company in San Francisco, creating quantitative measures of employee happiness, productivity, and ethics at companies, with the long-term intent of creating a consciousness research institute that’s also a great place to work for (i.e. one in which employees are happy, productive, and ethical). In his free time he develops psychophysical tools to study the computational properties of consciousness.

Schedule:

6:30: Check in, snacks

6:45: Structured schmoozing

6:55: Event intro and meditation

7:00: Andrés Gómez Emilsson

7:50: Break

8:00: Break-out Sessions (small group discussion)

9:00: Break-out Recap

9:15: Closing meditation

About our venue:

ECO-SYSTM is a dynamic community of creative professionals, startups, and freelancers, founded on the idea that entertainment, creativity and business can come together to offer a truly unique work experience for Bay Area professionals. Check out membership plans here: http://eco-systm.com/


 

The Penfield Mood Organ

Extract from Do Androids Dream of Electric Sheep? by Philip K. Dick (1968)

Chapter 1

A merry little surge of electricity piped by automatic alarm from the mood organ beside his bed awakened Rick Deckard. Surprised — it always surprised him to find himself awake without prior notice — he rose from the bed, stood up in his multicolored pajamas, and stretched. Now, in her bed, his wife Iran opened her gray, unmerry eyes, blinked, then groaned and shut her eyes again.

“You set your Penfield too weak”, he said to her. “I’ll reset it and you’ll be awake and — ”

“Keep your hand off my settings.” Her voice held bitter sharpness. “I don’t want to be awake.”

He seated himself beside her, bent over her, and explained softly. “If you set the surge up high enough, you’ll be glad you’re awake; that’s the whole point. At setting C it overcomes the threshold barring consciousness, as it does for me.” Friendlily, because he felt well-disposed toward the world — his setting had been at D — he patted her bare, pale shoulder.

“Get your crude cop’s hand away,” Iran said.

“I’m not a cop.” He felt irritable, now, although he hadn’t dialed for it.

“You’re worse,” his wife said, her eyes still shut. “You’re a murderer hired by the cops.”

“I’ve never killed a human being in my life.” His irritability had risen, now; had become outright hostility.

Iran said, “Just those poor andys.”

“I notice you’ve never had any hesitation as to spending the bounty money I bring home on whatever momentarily attracts your attention.” He rose, strode to the console of his mood organ. “Instead of saving,” he said, “so we could buy a real sheep, to replace that fake electric one upstairs. A mere electric animal, and me earning all that I’ve worked my way up to through the years.” At his console he hesitated between dialing for a thalamic suppressant (which would abolish his mood of rage) or a thalamic stimulant (which would make him irked enough to win the argument).

“If you dial,” Iran said, eyes open and watching, “for greater venom, then I’ll dial the same. I’ll dial the maximum and you’ll see a fight that makes every argument we’ve had up to now seem like nothing. Dial and see; just try me.” She rose swiftly, loped to the console of her own mood organ, stood glaring at him, waiting.

He sighed, defeated by her threat. “I’ll dial what’s on my schedule for today.” Examining the schedule for January 3, 2021, he saw that a businesslike professional attitude was called for. “If I dial by schedule,” he said warily, “will you agree to also?” He waited, canny enough not to commit himself until his wife had agreed to follow suit.

“My schedule for today lists a six-hour self-accusatory depression,” Iran said.

“What? Why did you schedule that?” It defeated the whole purpose of the mood organ. “I didn’t even know you could set it for that,” he said gloomily.

“I was sitting here one afternoon,” Iran said, “and naturally I had turned on Buster Friendly and His Friendly Friends and he was talking about a big news item he’s about to break and then that awful commercial came on, the one I hate; you know, for Mountibank Lead Codpieces. And so for a minute I shut off the sound. And I heard the building, this building; I heard the — ” She gestured.

“Empty apartments,” Rick said. Sometimes he heard them at night when he was supposed to be asleep. And yet, for this day and age a one-half occupied conapt building rated high in the scheme of population density; out in what had been before the war the suburbs one could find buildings entirely empty… or so he had heard. He had let the information remain secondhand; like most people he did not care to experience it directly.

“At that moment,” Iran said, “when I had the TV sound off, I was in a 382 mood; I had just dialed it. So although I heard the emptiness intellectually, I didn’t feel it. My first reaction consisted of being grateful that we could afford a Penfield mood organ. But then I realized how unhealthy it was, sensing the absence of life, not just in this building but everywhere, and not reacting — do you see? I guess you don’t. But that used to be considered a sign of mental illness; they called it ‘absence of appropriate affect.’ So I left the TV sound off and I sat down at my mood organ and I experimented. And I finally found a setting for despair.” Her dark, pert face showed satisfaction, as if she had achieved something of worth. “So I put it on my schedule for twice a month; I think that’s a reasonable amount of time to feel hopeless about everything, about staying here on Earth after everybody who’s smart has emigrated, don’t you think?”

“But a mood like that,” Rick said, “you’re apt to stay in it, not dial your way out. Despair like that, about total reality, is self-perpetuating.”

“I program an automatic resetting for three hours later,” his wife said sleekly. “A 481. Awareness of the manifold possibilities open to me in the future; new hope that — ”

“I know 481,” he interrupted. He had dialed out the combination many times; he relied on it greatly. “Listen,” he said, seating himself on his bed and taking hold of her hands to draw her down beside him, “even with an automatic cutoff it’s dangerous to undergo a depression, any kind. Forget what you’ve scheduled and I’ll forget what I’ve scheduled; we’ll dial a 104 together and both experience it, and then you stay in it while I reset mine for my usual businesslike attitude. That way I’ll want to hop up to the roof and check out the sheep and then head for the office; meanwhile I’ll know you’re not sitting here brooding with no TV.” He released her slim, long fingers, passed through the spacious apartment to the living room, which smelled faintly of last night’s cigarettes. There he bent to turn on the TV.

From the bedroom Iran’s voice came. “I can’t stand TV before breakfast.”

“Dial 888,” Rick said as the set warmed. “The desire to watch TV, no matter what’s on it.”

“I don’t feel like dialing anything at all now,” Iran said.

“Then dial 3,” he said.

“I can’t dial a setting that stimulates my cerebral cortex into wanting to dial! If I don’t want to dial, I don’t want to dial that most of all, because then I will want to dial, and wanting to dial is right now the most alien drive I can imagine; I just want to sit here on the bed and stare at the floor.” Her voice had become sharp with overtones of bleakness as her soul congealed and she ceased to move, as the instinctive, omnipresent film of great weight, of an almost absolute inertia, settled over her.

He turned up the TV sound, and the voice of Buster Friendly boomed out and filled the room. ” — ho ho, folks. Time now for a brief note on today’s weather. The Mongoose satellite reports that fallout will be especially pronounced toward noon and will then taper off, so all you folks who’ll be venturing out — ”

Appearing beside him, her long nightgown trailing wispily, Iran shut off the TV set. “Okay, I give up; I’ll dial. Anything you want me to be; ecstatic sexual bliss — I feel so bad I’ll even endure that. What the hell. What difference does it make?”

“I’ll dial for both of us,” Rick said, and led her back into the bedroom. There, at her console, he dialed 594: pleased acknowledgment of husband’s superior wisdom in all matters. On his own console he dialed for a creative and fresh attitude toward his job, although this he hardly needed; such was his habitual, innate approach without recourse to Penfield artificial brain stimulation.

 

The Forces At Work

        Recreational agents which are legal and socially sanctioned by respectable society aren’t, of course, popularly viewed as drugs at all. The nicotine addict and the alcoholic don’t think of themselves as practising psychopharmacologists; and so alas their incompetence is frequently lethal.

        Is such incompetence curable? If it is, and if the abolitionist project can be carried forward with pharmacotherapy in advance of true genetic medicine, then a number of preconditions must first be in place. A necessary and sufficient set could not possibly be listed here. It is still worth isolating and examining below several distinct yet convergent societal trends of huge potential significance.

  1. First, it must be assumed that we will continue to seek out and use chemical mood-enhancers on a massive, species-wide scale.
  2. Second, a pioneering and pharmacologically (semi-)literate elite will progressively learn to use their agents of choice in a much more effective, safe and rational manner. The whole pharmacopoeia of licensed and unlicensed medicines will be purchasable globally over the Net. As the operation of our 30,000 plus genes is unravelled, the new discipline of pharmacogenomics will allow drugs to be personally tailored to the genetic makeup of each individual. Better still, desirable states of consciousness that can be induced pharmacologically can later be pre-coded genetically.
  3. Third, society will continue to fund and support research into genetic engineering, reproductive medicine and all forms of biotechnology. This will enable the breathtaking array of designer-heavens on offer from third-millennium biomedicine to become a lifestyle choice.
  4. Fourth, the ill-fated governmental War On (some) Drugs will finally collapse under the weight of its own contradictions. Parents are surely right to be anxious about many of today’s illegal intoxicants. Yet their toxicity will no more prove a reason to give up the dream of Better Living Through Chemistry than the casualties of early modern medicine are a reason to abandon contemporary medical science for homeopathy.
  5. Fifth, the medicalisation of everyday life, and of the human predicament itself, will continue apace. All manner of currently ill-defined discontents will be medically diagnosed and classified. Our innumerable woes will be given respectable clinical labels. Mass-medicalisation will enable the big drug companies aggressively to extend their lucrative markets in medically-approved psychotropics to a widening clientele. New and improved mood-modulating alleles, and other innovative gene-therapies for mood- and intellect-enrichment, will be patented. They will be brought to market by biotechnology companies eager to cure the psychopathologies of the afflicted; and to maximise profits.
  6. Sixth, in the next few centuries an explosive proliferation of ever-more sophisticated virtual reality software products will enable millions, and then billions, of people to live out their ideal fantasies. Paradoxically, as will be seen, the triumph of sensation-driven wish-fulfilment in immersive VR will also demonstrate the intellectual bankruptcy of our old Peripheralist nostrums of social reform. Unhappiness will persist. The hedonic treadmill can’t succumb to computer software.
  7. Seventh, secularism and individualism will triumph over resurgent Islamic and Christian fundamentalism. An entitlement to lifelong well-being in this world, rather than the next, will take on the status of a basic human right.

         There are quite a few imponderables here. Futurology is not, and predictably will never become, one of the exact sciences. Conceivably, one can postulate, for instance, the global triumph of an anti-scientific theocracy. This might be in the mould of the American religious right; or even some kind of Islamic fundamentalism. Less conceivably, there might be a global victory of tender-minded humanism over the onward march of biotechnical determinism. It is also possible that non-medically-approved drug use could be curtailed, at least for a time, with intrusive personal surveillance technologies and punishments of increasingly draconian severity. Abetted by the latest convulsion of moral panic over Drugs, for example, a repressive totalitarian super-state could institute a regime of universal compulsory blood-tests for banned substances. Enforced “detoxification” in rehabilitation camps for offenders would follow.

        These scenarios and their variants are almost certainly too alarmist. Given a pervasive ethos of individualism, and the worldwide spread of hedonistic consumer-capitalism, then as soon as people discover that there is no biophysical reason on earth why they can’t be as happy as they choose indefinitely, it will be hard to stop more adventurous spirits from exploring that option. Lifelong ecstasy isn’t nearly as bad as it sounds.

David Pearce in The Hedonistic Imperative (chapter 3)

 

Psychedelic Science 2017: Take-aways, impressions, and what’s next

 

It would be impossible for me to summarize what truly went on at Psychedelic Science 2017. Since giving a fair and detailed account of all of the presentations, workshops and social events I attended is out of the question, I will restrict myself to talking about, what I see as, the core insights and take-aways from the conference (plus some additional impressions I’ll get to). In brief, the core insights are: (1) that we are on the brink of a culturally-accepted scientific revolution on the study of consciousness in which we finally navigate our way out of our current pre-Galilean understanding of the mind, (2) that the breakdown of both the extremes of nihilism and eternalism as ideological north-stars in consciousness research is about to take place (i.e. finding out that neither scientific materialism nor spirituality convey the full picture), and (3) that a new science of valence, qualia, and rational psychonautics based on the quantification of good and bad feelings is slowly making its way into the surface.

With regards to (1): It should not come as a surprise to anyone who has been paying attention that there is a psychedelic renaissance underway. Bearing extreme world-wide counter-measures against it, in so far as psychedelic and empathogenic compounds meet the required evidentiary standards of mainstream psychopharmacology as safe and effective treatments for mental illness (and they do), they will be a staple of tomorrow’s tools for mental health. It’s not a difficult gamble: the current studies being made around the world are merely providing the scientific backing of what was already known in the 60s (for psychedelics) and 80s (for MDMA). I.e. That psychedelic medicine (people love to call it that way) in the right set and setting produces outstanding clinically-relevant effect sizes.

On (2): it is very unclear what people who attended the conference believe about the nature of reality, but overall there was a strong Open Individualist undercurrent and a powerful feeling that transcendence is right next door (even the urinals had sacred geometry*). That said, the science provided a refreshing feeling of cautious nihilism. Trying to reconcile both love and science is, in my opinion, the way to go. Whether we are about to ascend to another realm or if we are about to find out about our cosmic meaninglessness, the truth is that there are a lot of more immediate things to worry about. Arguably, psychedelic experiences could be used to treat both the afflictions that come with eternalism as well as those that come from nihilism. Namely, psychedelics often make you experience the world as you believe it to be (echoing John C. Lilly’s famous words: “In the province of the mind, what one believes to be true is true or becomes true, within certain limits to be found experientially and experimentally. These limits are further beliefs to be transcended. In the mind, there are no limits…”). So if you rely on intense (but mundanely challenged) feelings of transcendence to get by, you may find out on a psychedelic experience that making a world in which what you believe is literally true does not lead to happiness and meaningfulness in the way you thought it might. Unless, of course, one believes that everything that happens is a net positive somehow (which is hard to do given the regular onslaught of meaninglessness found in everyday life), any profound realization of an ontological basis of reality (as in “a made up universe perceived as if real”) can lead to dysphoria. Nihilism can be profoundly distressing on psychedelics. Yet, as evidenced by the bulk of conscious experiences, the quality of meaningfulness in one’s experience is a continuum, neither objective nor subjective, and neither eternal nor unreal (I’m using the terminology from the book “Meaningness“, though other terminologies exist for similar concepts such as the Buddhist “middle way”, Existentialism, Pragmatism, Rationalists’ epistemic rationality, etc.).

Psychedelic veterans usually end up converging on something that has this sort of emotional texture: A bitter-sweet yet Stoic worldview that leaves an open space for all kinds of wonderful things to happen, yet remains aware of the comings and goings of happiness and fulfillment. It makes it a point to not be too preoccupied with questions of ultimate meaning. It may be that for most people it’s impossible to arrive at such wisdom without trying out (and failing in some way) to live all of their fantasies before giving up and accepting the fluxing nature of reality. In such a case, psychedelics would seem to offer us a way to accelerate our learning about the unsatisfactoriness of attachments and find the way to live in realistic joy.

That said, maybe such wisdom is not Wisdom (in the sense of being universal) since we are restricting our analysis to the human wetware as it is today.  What reason do we have to believe that the hedonic treadmill is a fundamental property of the universe? A lot of evidence suggests persistent differences in people’s hedonic set-point (often genetically influenced, as in the case of the SCN9A gene for pain thresholds), and this challenges the notion that we can’t avoid suffering. Indeed, MDMA-like states may some day be experienced at will with the use of technology (and without side effects). There may even be scientifically-derived precision-engineered ethical and freedom-expanding wireheading technology that will make our current everyday way of life look laughably uninteresting and unmeaningful in comparison.

Unfortunately, talking about this (i.e. technologically-induced hedonic recalibration) with people who need a pessimistic metaphysics of valence just to function may be considered antisocial. For example, some people seem to need spiritual theories of the pleasure-pain axis that focus on fairness (such as the doctrine of Karma) in order to feel like they are not randomly getting the shorter end of the (cosmic) stick (this sentiment usually comes together with implicit Closed Individualist convictions). Of course feeling like one is a victim is itself the result of one’s affect. This provides the perfect segway for (3):

In addition to all of the magical (but expected) fusion of art, psychotherapy, mysticism, spirituality and self-hacking that this conference attracted, I was extremely delighted to see the hints of what I think will change the world for the better like nothing else will: psychedelic valence research.

Of particular note is the work of Dráulio Barros de Araújo (“Rapid Antidepressant Effects of the Psychedelic Ayahuasca in Treatment-Resistant Depression: A Randomized Placebo-Controlled Trial”), Mendel Kaelen (“The Psychological and Neurophysiological Effects of Music in Combination with Psychedelics”), Leor Roseman (“Psilocybin-Assisted Therapy: Neural Changes and the Relationship Between Acute Peak Experience and Clinical Outcomes”), Jordi Riba (“New Findings from Ayahuasca Research: From Enhancing Mindfulness Abilities to Promoting Neurogenesis”), Selen Atasoy (“Enhanced Improvisation in Brain Processing by LSD: Exploring Neural Correlates of LSD Experience With Connectome-Specific Harmonic Waves”), Tomas Palenicek (“The Effects of Psilocybin on Perception and Dynamics of Induced EEG/fMRI Correlates of Psychedelic Experience”) and Clare Wikins (“A Novel Approach to Detoxification from Methadone Using Low, Repeated, and Cumulative Administering of Ibogaine”).

And of all of these, Selen Atasoy‘s work seems to be hitting the nail in the head the most: Her work involves looking into how psychedelics affect the overall amount of energy that each of the brain’s discrete connectome-specific resonant states has. Without giving it away (their work with LSD is still unpublished) let me just say that they found that having some extra energy in specific harmonics was predictive of the specific psychedelic effects experienced at a given point in time (including things such as emotional arousal, deeply felt positive mood, and ego dissolution).

Remarkably, this line of work is in agreement with Mike Johnson’s theoretical framework for the study of valence (as outlined in Principia Qualia). Namely, that there is a deep connection between harmony, symmetry and valence that will make sense once we figure out the mathematical structure whose formal properties are isomorphic to a subject’s phenomenology. In particular, “Valence Structuralism” would seem to be supported by the findings that relatively pure harmonic states are experienced as positive emotion. We would further predict that very pure harmonic states would have the highest level of (positive) hedonic tone (i.e. bliss). We are indeed very intrigued by the connectome-specific harmonic approach to psychedelic research and look forward to working with this paradigm in the future. It would be an understatement to say that we are also excited to see the results of applying this paradigm to study MDMA-like states of consciousness. This line of research is, above all, what makes me think that this year is the Year of Qualia (whether we have realized it or not). As it were, we are seeing the first hints of a future science of consciousness that can finally provide quantitative predictions about valence, and hence, become the first scientifically-compliant theory of ultimate value.

And now some subjective impressions about the conference…

Impressions

Psychedelic Ambiance

At its core, the conference felt extremely psychedelic in its own right. The artwork, people’s attires, the scents, the background music, etc. were all what seemed to me like expressions of an emerging style of psychedelic ambiance: A euphoric blend of MDMA-like self-assurant empathegenesis vibes (“everything will be ok”) with an LSD-like ontological sabotage to the ego entheoblasting vibes of universal oneness (“things are not what they seem/everything already always and never has happened at the same time”). Peak experiences, after all, often involve the metaphorical reconciliation of the divine and the mundane in a cosmic dance of meaning.

The Gods

In his book “Simulations of God” John C. Lilly proposes that beneath the surface of our awareness, each and every mind worships a number of seemingly transcendental values (sometimes, but not always, explicitly personified). Whether we know it or not, he argues, each and every one of us treats as if a God at least something. Whether we think there there is a “God Out There”, that “Truth is the Ultimate God”, or that “God Is The Group”, the highest node in our behavioral hierarchy is always covertly managed by our basic assumptions about reality (and what they prescribe as “intrinsically good”). The book’s table of contents is awesome; it outlines what ends up being the bulk of what humans ever care about as their ultimate values:

  1. God As the Beginning
  2. I Am God
  3. God Out There
  4. God As Him/Her/It
  5. God As The Group
  6. God As Orgasm and Sex
  7. God As Death
  8. God As Drugs
  9. God As the Body
  10. God As Money
  11. God As Righteous Wrath
  12. God As Compassion
  13. God As War
  14. God As Science
  15. God As Mystery
  16. God As the Belief, the Simulation, the Model
  17. God As the Computer
  18. God Simulating Himself
  19. God As Consciousness-without-an-Object
  20. God As Humor
  21. God As Superspace, the Ultimate Collapse into the Black Hole, the End.
  22. The Ultimate Simulation
  23. God As the Diad

Perhaps what’s most amazing about psychedelics is that they are capable of changing one’s Gods. It’s extremely common for people who take psychedelics to de-emphasize traditionalist and mainstream Gods such as 1, 3, 5, 7, 10, 11, 13, while also having experiences (and changes of mind) that push them to emphasize 2, 6, 8, 12, 14, 15, 16, 17, 18, 19, 21, 22, and 23. But one wonders, what’s the eventual steady-state? As an umbrella description of what is going on we could say that psychedelics make you more open. But where does this, ultimately, lead?

Perhaps you started out in a conservative household and a family that emphasized loyalty to the group, conformism, nationalism and traditional religious values (1, 3, 5, 7). But once you tried LSD you felt a great change in the strength of your various deep-seated inclinations. You realize that you do not want to worship anything just to fit in, just to be part of a group, and that maybe caring about money is not as important as caring about making your own meaning out of life. You now feel like you care more about mysterious things like Orgasm (6), the Mind-Body connection (9), and philosophical questions like “If I am God, why would I build a universe with suffering in it?” (2, 15, 16, 21). You maybe watch some lectures by Alan Watts and read a book by Huxley, among other counter-culture material consumed, and you might start to develop a general belief in “the transcendent” but in a way that attempts to be compatible with the fact that you and the people you love experience suffering. You fantasize with the idea that maybe all of suffering is somehow necessary for some higher cosmic purpose (18, 19, 22) to which you are only made privy every now and then. You then continue on the path of psychedelic divination, perhaps taking more than you could handle here and there, and you are made aware of incredible universes: you meet guardians, you are led to read about Theosophy, you meet archetypes of the collective psyche, and after a while your strange experience with electronic equipment on LSD makes you wonder whether telepathy (at least an energetic and emotional variant of it) could be possible after all. But you do not ever obtain “good enough evidence” that would convince anyone who is determined to be a skeptic of your glitches of the Matrix. At some point, after taking too many magic mushrooms, you end up in what seems like a sort of Buddhist Hell: Feeling like we are all One no longer feels like a fact to be excited about, but rather, this is felt as a realization that should be forgotten as soon as one has it. Don’t let the cosmic boredom set in, don’t led nihilistic monism get to your very core. But it does, and you have a bad trip, one trip that you feel you never really recovered from, and whose nature is never talked about at psychedelic gatherings. (Don’t worry, right next door someone had a bad trip whose semantic content was the exact opposite of yours yet its effects on your corresponding valence landscapes were similar, e.g. concluding that “we are all made of atoms with no purpose” may feel just as bad as believing that “we are all God, and God is bored”). So maybe psychedelic therapy is a red herring after all, you think to yourself, and we should really be looking only into compounds that both increase euphoria and obfuscate the ultimate nature of reality at the same time. “Science, we need science” -you tell yourself- “so that we can figure out what it is that consciousness truly wants, and avoid both nihilistic bad trips as well as unrealistic eternalist mania”. Perhaps we are currently about to have to figure this out as a collective intelligence: “What do we do with the fact that we are all God?” This question is now making its way in etheric undercurrents in the shared meme-space of humanity just as the psychedelic renaissance starts to unfold.

The above paragraph is just one of the various archetypical ways in which psychedelic self-exploration may progress over time for a particular person. Of course not only do people’s progression vary; people’s starting points may be different. Some people approach psychedelics with spiritual intentions, others do so with recreation in mind, others use them for psychological self-exploration, and yet others use it to try to find glitches in reality. I would love to have a quantitative assessment of how one’s starting “implicit Gods” influence the way psychedelics affect you, and how such Gods evolve over the course of more exposure to psychedelic states of consciousness. There is a lot of wisdom-amplification research to be made on this front.

Psychedelic Gods

You’re only as young as the last time you changed your mind.

– Timothy Leary

The first thing I noticed at this conference was that this is a crowd that values both love and science. The geek in me seemed to be more than welcomed in here.

While I was able to enjoy the incredible vibe of the Bicycle Day celebration (just a day before the conference), I remember thinking that evolutionary psychology (cf. Mating Mind) would have a lot to say about it. A large proportion of seemingly selfless display of psychedelic self-sacrifice (e.g. LSD mega-dosing, spiritual training, asceticism, etc.) might in fact be just sexual signaling of fitness traits such as mental and physical robustness (cf. Algorithmic Reduction of Psychedelic StatesPolitical Peacocks). It’s hard to separate the universal love from the tribal mate-selection going on at raves and parties of this nature, and at times one may even get a bit of an anti-intellectual vibe for questioning this too deeply.

At the conference, though, I could tell there was another story going on. Namely, the God of Science made a prominent appearance, giving us all a sense of genuine progress beyond the comings and goings of the eternal game of hide-and-seek as one would expect in mere neo-hippy cyber-paganist events.

The God of Science… yes… if you think about it, holding an enriched concept of “science” (in its most expansive sense possible) while simultaneously trying to hold with equal intensity and expansiveness the intent of “love for all beings”, can make strange and wonderful things happen in your mind. Of salience is the fact that there will be an intense pull towards either only experiencing thought-forms about love or only focusing on thought-forms about science. Mixing the two requires a lot of energy. It’s almost as if we were wired to only focus on one at a time. This is an effect reminiscent to the mutual inhibition between empathizing and systematizing cognitive styles, and maybe at its core, the difficulty in blending both love and science without residue is a reflection of an underlying invariant. Under the assumption that you have a limited amount of positive valence at your disposal to paint your world simulation, and that you want to achieve clarity of mind, it is possible that you will have to front-load most of that positive valence in either broad quantitative observations (systematizing) or focused feelings of specialness and intimacy (empathizing). This is why, for instance, MDMA and 2C-B are so promising for cognitive transhumanism: these compounds can give rise to experiences in which there is a huge surplus of positive valence ready to be used to paint any aspect of your world simulation with bliss qualia. Sadly, this is a property of such states of consciousness, and it cannot currently be brought into our everyday lives as it is. Without serious genetic engineering (or other valence-enhancing technologies) all we can do for now is to make use of these states of consciousness to catalyze changes in our deep-seated existential stances in order to help us get by in our half-meaningful half-meaningless everyday life.

Of course, the Holy Grail of mental health interventions would be a technology that allows us to instantiate a context-dependent level of empathogenesis in a reliable and sustainable way. When I asked people at the conference whether they thought that having “a machine that makes you feel like you are on MDMA on demand with no tolerance, impulsivity, addiction or other side effects” would be good, most people (at least 80%) said “it would be bad for humanity to have such machine”. Why? Because they think that suffering serves a higher purpose, somehow. But I would disagree. And even if they are right, I still think that there are not enough people steel-manning the case for intelligent wire-heading. It’d be silly to find out in 2200 that we could have avoided hundreds of millions of people’s suffering at no cost to our collective growth if we only had thought more carefully about the intrinsic value of suffering back in 2050 when the MDMA-machine was invented and reflexively banned.

But healthy sustainable wire-heading (let alone wire-heading done right in light of evolution-at-the-limit scenarios) is many decades away into the future anyway. So all we have for now, by way of consciousness-expanding therapies for real-life knots-and-bolts treatment-resistant human suffering is the sort of therapy paradigms discussed in the conference. Of the roughly 135 conference talks (excluding parties, networking events, and workshops) at least 100 were either only or at least primarily focused on psychedelic therapy for mental illness (cancer end-of-life anxiety, PTSD, addiction, treatment-resistant depression, etc.). As far as a strategical cultural move, this focus on treatment is a very good approach, and from a valence utilitarian point of view maybe this is indeed what we should be focusing on in 2017. But I still wish that there was a bigger presence of some other kinds of discussion. In particular, I’d love for psychedelic science to eventually make a prominent appearance in a much wider context. Any discussion about the nature of consciousness from a scientific point of view cannot overlook the peculiar consciousness-enhancing properties of psychedelics. And any discussion about ethics, life and the purpose of it all will likewise be under-informed in so far as psychedelic peak-meaningful experiences are not brought into the conversation. After all, the ethical, philosophical, and scientific significance of psychedelics is hard to overstate.

Ideally we would all organize a conference that takes the best of: 1) A steadfast resolution to figure out the problem of consciousness, such as what we can find at places like The Science of Consciousness, 2) a steadfast resolution to combine both the best of compassion and rationality in order to help as many beings as possible, as we find in places like Effective Altruism Global, and 3) a steadfast resolution to look at the most impressive pieces of evidence about the nature of the mind and valence, as can be found in places like Psychedelic Science. All in all, this would be a perfect triad, as it would combine (1) The Question (Consciousness), (2) The Purpose (Ending Suffering), and (3) The Method (Scientific Study of Highly-Energetic States of Consciousness). Rest assured, the conferences organized by the Super-Shulgin Academy will blend these three aspects into one.

The Crowd

This was a very chill crowd. The only way for me to be edgy in the social contexts that arose at Psychedelic Science 2017 was to refuse to dab with the guy next to me (and to decline the Asparagus Butternut Squash edible offered at some point), or, at its worse, trying to spark a conversation about the benefits of well-managed opioid medication treatment for chronic pain (it was a rather opioid-phobic crowd, if I may say so myself).

On the other hand, talking about one’s experience in hyperbolic phenomenal spaces while on DMT, how to secretly communicate with people on LSD, and about the use of texture analysis and synthesis for psychophysical tasks to investigate psychedelic image processing barely raised anybody’s brows. I was happy to find that some people recognized me from Qualia Computing, and more than one of them shared the thought that it would be great to see more interbreeding and cross-fertilization between the psychedelic and the rationalist communities (I can’t agree more with this sentiment).

To give you a taste of the sort of gestalt present at this event, let me share with you something. Waiting on the line for one of the parties hosted by the conference organizers I overheard someone talking about what his ketamine experiences had taught him. Curious about it, I approached him and asked him to debrief me -if at all possible -about what he had learned. He said:

The super-intelligence that I’ve encountered on my ketamine experiences is far, far, beyond human comprehension, and its main message is that everything is interconnected; it does not matter when you hear the message, but that you hear it, and unconsciously prepare for what is going to happen. We are all soon going to be part of it, and we will all be together, knowing each other at a deeper level than we have ever thought imaginable, and experience love and meaning on another level, together in a vast interdimensional ecology of benevolent minds. All of the stories that we tell ourselves about the grand human narrative are all, well, made up by our minds on our limited human level. Whatever we are coming to, whatever this future thing that we are facing is, goes beyond human cravings for transcendence, it goes beyond the sentiment of return to nature, it goes beyond science and technology, and it goes beyond every religion and contemplative practice. The complexity to be found in the super-intelligent collective being that we will become is inexpressible, but there is nothing to fear, we are it on some level already, and we will soon all realize it.

It is hard to estimate what the distribution, prevalence and resilience of beliefs about the nature of reality, consciousness, love, purpose and everything else of the people attending this conference were. As a whole, it felt remarkably diverse, though. Based on my subjective impressions, I’d suspect that like the person quoted above, about 40% of the attendees were people who genuinely believe that there is a big consciousness event that is about to happen (whether it is a collective spiritual level-breaking point, a technological Singularity, inter-dimensional aliens taking us with them, or a more mundane run-of-the-mill recursively self-improving feedback loop with genetic methods for consciousness research). Maybe about 50% seemed to be what you might call pragmatic, agnostic, and open minded people who are simply looking to find out what’s up with the field, without spiritual (or emotional) vested interested in exactly what will happen. And finally, about 10% of the attendees might be classifiable as nihilists on some or another level. While intrigued about the effects of psychedelics, they see them as dead ends or red herrings. Perhaps useful for mental health, but not likely to be a key to reality (or even a hint of a future revolution in the states of consciousness we utilize on our everyday life).

Conclusion

I am very excited with the current movement to examine psychedelics in a rational scientific framework. Ultimately, I think that we will realize that valence is a quantifiable and definite thing (cf. Valence Structuralism). Wether we are talking about humor, pain relief, transcendence, or knots-and-bolts feelings of competence, all of our positive experiences share something in common. Ultimately, I do not know whether “valence is a spiritual trick” or if “spirituality is a valence trick”, but I am confident that as a species we do not yet have the answer to these questions and that a scientific approach to them may clarify this incredibly important line of inquiry.

Sooner or later, it seems to me, we will figure out what exactly “the universe wants from us”, so to speak, and then nothing will ever be the same; psychedelic research is a powerful and promising way to make good headway in this highly desirable direction.

 

 

 

IMG_20170421_212302

The look from the Sunset Cruise at the Psychedelic Science 2017 Conference


*Even the bathroom urinals seemed to have sacred geometry:

 

IMG_20170423_192257

Even the urinals had sacred geometry… reminding you of the interconnectedness of all things at the unlikeliest of moments.

Their Scientific Significance is Hard to Overstate

I think it’s hard to overstate the cognitive significance of major psychedelics for the future of sentience. But it’s also hard to convey why these agents can be valuable tools of investigation to academics who have never tried them. I know distinguished drug-naive philosophers of mind (and transhumanists) who are certain that psychedelia can’t be significant – and it would be irresponsible to urge them to put their assumptions to the test. Perhaps the best I can do is offer an analogy. Imagine an ultra-intelligent tribe of congenitally blind extraterrestrials. Their ignorance of vision and visual concepts is not explicitly represented in their conceptual scheme. To members of this hypothetical species, visual experiences wouldn’t be information-bearing any more than a chaotic drug-induced eruption of bat-like echolocatory experiences would be information-bearing to us. Such modes of experience have never been recruited to play a sensory or signaling function. At any rate, some time during the history of this imaginary species, one of the tribe discovers a drug that alters his neurochemistry. The drug doesn’t just distort his normal senses and sense of self. It triggers what we would call visual experiences: vivid, chaotic in texture and weirder than anything the drug-taker had ever imagined. What can the drug-intoxicated subject do to communicate his disturbing new categories of experiences to his tribe’s scientific elite? If he simply says that the experiences are “ineffable”, then the sceptics will scorn such mysticism and obscurantism. If he speaks metaphorically, and expresses himself using words from the conceptual scheme grounded in the dominant sensory modality of his species, then he’ll probably babble delirious nonsense. Perhaps he’ll start talking about messages from the gods or whatever. Critically, the drug user lacks the necessary primitive terms to communicate his experiences, let alone a theoretical understanding of what’s happening. Perhaps he can attempt to construct a rudimentary private language. Yet its terms lack public “criteria of use”, so his tribe’s quasi-Wittgensteinian philosophers will invoke the (Anti-)Private Language Argument to explain why it’s meaningless. Understandably, the knowledge elite are unimpressed by the drug-disturbed user’s claims of making a profound discovery. They can exhaustively model the behaviour of the stuff of the physical world with the equations of their scientific theories, and their formal models of mind are computationally adequate. The drug taker sounds psychotic. Yet from our perspective, we can say the alien psychonaut has indeed stumbled on a profound discovery, even though he has scarcely glimpsed its implications: the raw materials of what we would call the visual world in all its glory.

 

Anyhow, I worry that our own predicament resembles in more extreme form the hubris of the blind super-rationalists I describe above. In fact, intellectually, I worry far more about my ignorance of other modes of conscious existence than I do my cognitive biases or deficiencies of reasoning within ordinary waking consciousness. Sure, I’d love to know the master equation of a unified field theory. I’d love even more to know what it’s like to inhabit a world of echolocation like a bat – and to understand the indescribable weirdness of LSD, DMT or Salvia. It transpires that ordinary waking and dreaming consciousness are just two among numerous wholly or partially incommensurable realms of sentience. What we call waking consciousness was doubtless a fitness-enhancing adaptation in the ancestral environment of adaptation. But it occupies only a tiny fraction of experiential state-space. Our ignorance is all the more insidious because it is not explicitly represented in our conceptual scheme. From the inside, a dreamer has little insight into the nature of a dream, even in rare moments of “lucid dreaming”; and I fear this may be true of ordinary waking consciousness too. Unfortunately, the only way to even partially apprehend the nature of radically altered states is by first-person investigation, i.e. to instantiate the neurochemical substrates of the states in question. If drug-naive, you can’t fruitfully read about them. Compare how (ostensibly) trivial is the difference in the gene expression signature of neurons mediating phenomenal colour and sound. Who knows what further categories of experience other “trivial” bimolecular variations will open up, not to speak of more radical neurochemical changes? Thousands of scholarly philosophy papers and books have been written on consciousness in recent years by drug-naive academics. Psychedelic researchers worry that too many of them evoke Aristotelean scholasticism, whereas what we need is a post-Galilean experimental science of consciousness. Perhaps the nearest I come to an intellectual hero is psychedelic chemist Alexander Shulgin, whose pioneering methodology is described in PiHKAL. Alas, Shulgin doesn’t yet occupy a prominent place in the transhumanist pantheon.

 

It’s worth stressing that taking psychedelics is not a fast-track passport to either happiness or wisdom. If you take the kappa opioid agonist Salvinorin A found in Salvia divinorum, for instance, you might easily have a waking nightmare. And the experience may easily be unintelligible rather than illuminating. Even in a society of sighted people and a rich visually-based conceptual scheme, it takes years for a congenitally blind person who is surgically granted the gift of sight to master visual literacy. So understanding the implications of radically altered states may well take millennia. I’d hazard a guess and say comprehension will take millions of years and more. Either way, our descendants may be not just superintelligent but supersentient – blessed with the capacity to shift between a multitude of radically different modes of consciousness whose only common ingredient is the molecular signature of bliss. Posthuman mastery of reward circuitry will let them safely explore psychedelia in a way most humans beings don’t dare. Yes, it’s prudent for us to play safe; but in consequence our consciousness may be comparatively shallow and one-dimensional. Mine is today.

 
David Pearce‘s response to a question during an H+ interview (Autumn 2009)

GHB vs. MDMA

A brief comparison of GHB and MDMA may be instructive because one therapeutic challenge ahead will be to design agents that reverse SSRI-like flattening of affect without inducing mawkish sentimentalism (cf. ethyl alcohol). In contrast to mainstream psychiatric drug therapies, both GHB and MDMA deliver a rare emotional intensity of experience, albeit an intensity different both in texture and molecular mechanism. GHB is known by clubbers if not structural chemists as “liquid ecstasy”. GHB and MDMA are indeed sometimes mixed at raves; but the two drugs are chemically unrelated. GHB is an endogenous neuromodulator derived from GABA, the main inhibitory neurotransmitter of the brain. A naturally-occurring fatty acid derivative, GHB is a metabolite of normal human metabolism. GHB has its own G protein-coupled presynaptic receptor in the brain. Sold as a medicine, GHB is licensed as an oral solution under the brand name Xyrem for the treatment of cataplexy associated with narcolepsy. Unlike MDMA, GHB stimulates tissue serotonin turnover. GHB increases both the transport of tryptophan to the brain and its uptake by serotonergic cells. Taking GHB stimulates growth hormone secretion; hence its popularity with bodybuilders. GHB offers cellular protection against cerebral hypoxia, and deep sleep without inducing a hangover. GHB also stimulates tyrosine hydroxylase. Tyrosine hydroxylase converts L-tyrosine to L-dopa, subsequently metabolised to dopamine. Unlike MDMA, the acute effects of GHB involve first inhibiting the dopamine system, followed the next day by a refreshing dopamine rebound. GHB induces mild euphoria in many users. In general, the neurotransmitter GABA acts to reduce the firing of the dopaminergic neurons in the tegmentum and substantia nigra. The sedative/hypnotic effect of GHB is mediated by its stimulation of GABA(B) receptors, though GHB also modulates the GABA(A) receptor complex too. The main effect of GABA(B) agonism is normally muscle relaxation, though interestingly, pretreatment with the GABA(B) agonist baclofen also prevents an MDMA-induced rise in core body temperature. Whatever the exact GABA(A), GABA(B), and GHB-specific mechanisms by which GHB works, when taken at optimal dosage GHB typically acts as a “sociabiliser”. This is a term popularised by the late Claude Rifat (Claude de Contrecoeur), author of GHB: The First Authentic Antidepressant (1999). Rifat was GHB’s most celebrated advocate and an outspoken critic of Anglo-American psychiatry. Similar therapeutic claims have been made for GHB as for MDMA, despite their pharmacological differences. GHB swiftly banishes depression and replaces low mood with an exhilarating feeling of joy; GHB has anxiolytic properties; it’s useful against panic attacks; it suppresses suicidal ideation; it inhibits hostility, paranoia and aggression; it enhances the recall of long-forgotten memories and dreams; and it promotes enhanced feelings of love. Like MDMA, and on slightly firmer grounds, GHB has been touted as an aphrodisiac: GHB heightens and prolongs the experience of orgasm. GHB disinhibits the user, and deeply relaxes his or her body. Inevitably, GHB has been demonised as a date-rape drug [“I was at this party, and this guy gave me a drink. Next thing I know, it’s morning and I’m in someone’s bed. I’ve no idea what happened in between…”]. GHB has a steep dose-response curve. Higher doses will cause anterograde amnesia i.e. users forget what they did under the influence of the drug. It’s dangerous to combine GHB with other depressants. So despite GHB’s therapeutic and pro-social potential, GHB is probably unsafe to commend to clubbers. This is because a significant percentage of the population will combine any drug whatsoever with alcohol regardless of the consequences to health. If used wisely, sparingly, and in a different cultural milieu, then GHB could be a valuable addition to the bathroom pharmacopoeia. But even then, it’s still flawed. GHB may intensify emotion and affection, but not introspective depth or intellectual acuity. Unlike taking too much MDMA, overdoing GHB makes the user fall profoundly asleep. If our consciousness is to be durably enhanced, then sedative-hypnotics have only a limited role to play in the transition ahead.

– Extract from “Utopian Pharmacology: Mental Health in the Third Millennium
MDMA and Beyond” by David Pearce (notice the great domain name: mdma.net)

Hedonium

Desiring that the universe be turned into Hedonium is the straightforward implication of realizing that everything wants to become music.

The problem is… the world-simulations instantiated by our brains are really good at hiding from us the what-it-is-likeness of peak experiences. Like Buddhist enlightenment, language can only serve as a pointer to the real deal. So how do we use it to point to Hedonium? Here is a list of experiences, concepts and dynamics that (personally) give me at least a sort of intuition pump for what Hedonium might be like. Just remember that it is way beyond any of this:

Positive-sum games, rainbow light, a lover’s everlasting promise of loyalty, hyperbolic harmonics, non-epiphenomenal bliss, life as a game, fractals, children’s laughter, dreamless sleep, the enlightenment of emptiness, loving-kindness directed towards all sentient beings of past, present, and future, temperate wind caressing branches and leaves of trees in a rainforest, perfectly round spheres, visions of a giant ying-yang representing the cosmic balance of energies, Ricci flowtranspersonal experiences, hugging a friend on MDMA, believing in a loving God, paraconsistent logic-transcending Nirvana, the silent conspiracy of essences, eating a meal with every flavor and aroma found in the quantum state-space of qualia, Enya (Caribbean Blue, Orinoco Flow), seeing all the grains of sand in the world at once, funny jokes made of jokes made of jokes made of jokes…, LSD on the beach, becoming lighter-than-air and flying like a balloon, topological non-orientable chocolate-filled cookies, invisible vibrations of love, the source of all existence infinitely reflecting itself in the mirror of self-awareness, super-symmetric experiences, Whitney bottles, Jhana bliss, existential wonder, fully grasping a texture, proving Fermat’s Last theorem, knowing why there is something rather than nothing, having a benevolent social super-intelligence as a friend, a birthday party with all your dead friends, knowing that your family wants the best for you, a vegan Christmas eve, petting your loving dog, the magic you believed in as a kid, being thanked for saving the life of a stranger, Effective Altruism, crying over the beauty and innocence of pandas, letting your parents know that you love them, learning about plant biology, tracing Fibonacci spirals, comprehending cross-validation (the statistical technique that makes statistics worth learning), reading The Hedonistic Imperative by David Pearce, finding someone who can truly understand you, realizing you can give up your addictions, being set free from prison, Time Crystals, figuring out Open Individualism, G/P-spot orgasm, the qualia of existential purpose and meaning, inventing a graph clustering algorithm, rapture, obtaining a new sense, learning to program in Python, empty space without limit extending in all directions, self-aware nothingness, living in the present moment, non-geometric paradoxical universes, impossible colors, the mantra of Avalokiteshvara, clarity of mind, being satisfied with merely being, experiencing vibrating space groups in one’s visual field, toroidal harmonics, Gabriel’s Oboe by Ennio Morricone, having a traditional dinner prepared by your loving grandmother, thinking about existence at its very core: being as apart from essence and presence, interpreting pop songs by replacing the “you” with an Open Individualist eternal self, finding the perfect middle point between female and male energies in a cosmic orgasm of selfless love, and so on.

The Hyperbolic Geometry of DMT Experiences: Symmetries, Sheets, and Saddled Scenes

[Content Warning: Trying to understand the contents of this essay may be mind-warping. Proceed with caution.]

Friends, right here and now, one quantum away, there is raging a universe of active intelligence that is transhuman, hyperdimensional, and extremely alien.

—Terence McKenna

The Geometry of DMT States

This is an essay on the phenomenology of DMT. The analysis here presented predominantly uses algorithmic, geometric and information-theoretic frameworks, which distinguishes it from purely phenomenological, symbolic, neuroscientific or spiritual accounts. We do not claim to know what ultimately implements the effects here described (i.e. in light of the substrate problem of consciousness), but the analysis does not need to go there in order to have explanatory power. We posit that one can account for a wide array of (apparently diverse) phenomena present on DMT-induced states of consciousness by describing the overall changes in the geometry of one’s spationtemporal representations (what we will call “world-sheets” i.e. 3D + time surfaces; 3D1T for short). The concrete hypothesis is that the network of subjective measurements of distances we experience on DMT (coming from the relationships between the phenomenal objects one experiences in that state) has an overall geometry that can accurately be described as hyperbolic (or hyperbolic-like). In other words, our inner 3D1T world grows larger than is possible to fit in an experiential field with 3D Euclidean phenomenal space (i.e. an experience of dimension R2.5 representing an R3 scene). This results in phenomenal spaces, surfaces, and objects acquiring a mean negative curvature. Of note is that even though DMT produces this effect in the most consistent and intense way, the effect is also present in states of consciousness induced by tryptamines and to a lesser extent in those induced by all other psychedelics.

Conceptual Framework: Algorithmic Reduction

We will use the reduction framework originally proposed in the article Algorithmic Reductions of Psychedelic States. This means that we will be examining how algorithms and processes (as experienced by a subject of experience) can explain the dynamics of people’s phenomenology in DMT states. We do not claim “the substrate of consciousness” is becoming hyperbolic in any literal sense (though we do not discard that possibility). Rather, we interpret the hyperbolic curvature that experience acquires while on DMT as an emergent effect of a series of more general mechanism of action that can work together to change the geometry of a mind. These same mechanisms of action govern the dynamics of other psychedelic experiences; it is the proportion and intensity of the various “basic” effects that lead to the different outcomes observed. In other words, the hyperbolization of phenomenal space may not be a fundamental effect of DMT, but rather, it may be an emergent effect of more simple effects combined (not unlike how our seemingly smooth macroscopic space-time emerges from the jittery yet fundamental interactions that happen in a microscopic high-dimensional quantum foam).

In particular, we will discuss three candidate models for a more fundamental algorithmic reduction: (1) the synergistic effect of control interruption and symmetry detection resulting in a change of the metric of phenomenal space (analogously to how one can measure the geometry of hyperbolic graph embeddings), (2) the mind as a dynamic system with energy sources, sinks and invariants, in which curvature stores potential energy, and (3) a change in the underlying curvature of the micro-structure of consciousness. These models are not mutually-exclusive, and they may turn out to be compatible. More on this later.

What is Hyperbolic Geometry?

Perhaps the clearest way to describe hyperbolic space is to show examples of it:

The picture to the left shows a representation of a “saddle” surface. In geometry, saddle surfaces are 2-dimensional hyperbolic spaces (also called “hyperbolic planes” or H2). For a surface to have “constant curvature” it must look the same at every point. In other words, for a saddle to be a geometric saddle, every point in it must be a “saddle point” (i.e. a point with negative curvature). As you can see, saddles have the property that the angles of a triangle found in them add up to less than 180 degrees (compare that to surfaces with positive curvature such as the 2-sphere, in which the angles of a triangle add up to more than 180 degrees). Generalizing this to higher dimensions, the middle image above shows a cube in H3 (i.e. a hyperbolic space of three dimensions). This cube, since it is in hyperbolic space, has thin edges and pointy corners. More generally, the corners of a polyhedra (and polytopes) will be more pointy in Hn than they are in Rn. This is why you can see in the right image a dodecahedron with right-angled corners, which in this case can tile H3 (cf. Not Knot). Such a thing- people of the past might say- is an insult to the imagination. Times are changing, though, and hyperbolic geometry is now an acceptable subject of conversation.

An important property of hyperbolic spaces is the way in which the area of a circle (or the n-dimensional volume of a hypersphere) increases as a function of its radius. In 2D Euclidean space the area grows quadratically with the radius. But on H2, the area grows exponentially as a function of the radius! As you may imagine, it is easy to get lost in hyperbolic space. A few steps take you to an entirely different scene. More so, your influence over the environment is greatly diminished as a function of distance. For example, the habitable region of solar systems in hyperbolic spaces (i.e.the Goldilocks zone) is extremelly thin. In order to avoid getting burned or freezing to death you would have to place your planet within a very narrow distance range from the center star. Most of what you do in hyperbolic space either stays as local news or is quickly dissipated in an ever-expanding environment.

We Can Only Remember What We Can Reconstruct

We cannot experience H2 or H3 manifolds under normal circumstances, but we can at least represent some aspects of them through partial embeddings (i.e. instantiations as subsets of other spaces preserving properties) and projections into more familiar geometries. It is important to note that such representations will necessarily be flawed. As it turns out, it is notoriously hard to truly embed H2 in Euclidean 3D space, since doing so will necessarily distort some properties of the original H2 space (such as distance, angle, area, local curvature, etc.). As we will discuss further below, this difficulty turns out to be crucial for understanding why DMT experiences are so hard to remember. In order to remember the experience you need to create a faithful and memorable 3D Euclidean embedding of it. Thus, if one happens to experience a hyperbolic object and wants to remember as much of it as possible, one will have to think strategically about how to fold, crunch and deform such object so that it can be fit in compact Euclidean representations.

What about DMT suggests hyperbolic geometry?

Why should we believe that phenomenal space on DMT (and to a lesser extent on other psychedelics) becomes hyperbolic-like?  We will argue that the features people use to describe their trips as well as concrete mathematical observations of such features point directly to hyperbolic geometry. Here is a list of such features (arranged from least to most suggestive… you know, for dramatic effect):

  1. Perception of far-out travel (as we said, small movements in hyperbolic space lead to huge changes in the scene).
  2. Feelings of becoming big (you can fit a lot more inside a circle of radius r in hyperbolic space).
  3. The space experienced is often depicted as “more real and more dense than normal”.
  4. The use of terms like “mind-expanding” and “warping” to describe the effects of the drug are very common.
  5. People describing it as “a different kind of space” and frequently using the word “hyperspace” to talk about it.
  6. Difficulty integrating/remembering the objects and scenes experienced (e.g. “they were too alien to recall”).
  7. Constant movement/acceleration and change of perspectives which are often described as “unfolding scenes and expanding patterns” (cf. the chrysanthemum, jitterbox).
  8. Continuous change of the scene’s context through escape routes: A door that leads to a labyrinth that leads to branching underground tunnels that lead to mirror rooms that lead to endless windows, and the one you take leading you to a temple with thirty seven gates which lead you to a kale salad world etc. (example).
  9. Crowding of scene beyond the limits of Euclidean space (users frequently wondering “How was I able to fit so much in my mind? I don’t see any space for my experience to fit in here!”)
  10. Reported similarity with fractals.
  11. Omnipresence of saddles making up the structural constraints of the hallucinated scenes. For example, one often hears about experiencing scenes saturated with: joints, twists, bifurcations, curved alleys, knots, and double helixes.
  12. Looking at self-similar objects (such as cauliflowers) can get you lost in what seems like endless space. (Note: beware of the potential side effects of looking at a cauliflower on DMT*).
  13. PSIS-like experiences where people seem to experience multiple alternative outcomes from each event at the same time (this may be the result of “hyperbolic branching” through time rather than space).
  14. Psychedelic replication pictures usually include features that can be interpreted as hyperbolic objects embedded in Euclidean 3D.
  15. People describe “incredibly advanced mechanisms” and “impossible objects” that cannot be represented in our usual reality (e.g. Terence Mckenna’s self-dribbling basketballs).
  16. At least one mathematician has stated that what one experiences on DMT cannot be translated into Euclidian geometry (unlike what one experiences on LSD).
  17. We received a series of systematic DMT trip-reports by a math enthusiast and experienced psychonaut who claims that the surfaces experienced on DMT are typically composed of hyperbolic tilings (which imply a negative curvature; cf. wallpaper groups).

This article goes beyond claiming a mere connection between DMT and hyperbolic geometry. We will be more specific by addressing the aspects of the experience that can be interpreted geometrically. To do so, let us now turn to a phenomenological description of the way DMT experiences usually unfold:

The Phenomenology of DMT experiences: The 6 Levels

In order to proceed we will give an account of a typical vaporized DMT experience. You can think of the following six sections as stages or levels of a DMT journey. Let me explain. The highest level you get to depends on the dose consumed, and in high doses one experiences all of the levels, one at a time, and in quick succession (i.e. on high doses these levels are perceived as the stages of the experience). If one takes just enough DMT to cross over to the highest level one reaches during the journey for only a brief moment, then that level will probably be described as “the peak of the experience”. If, on the other hand, one takes a dose that squarely falls within the milligram range for producing a given level, it will be felt as more of a “plateau”. Each level is sufficiently distinct from the others that people will rarely miss the transitions between them.

The six levels of a DMT experience are: Threshold, Chrysanthemum, Magic Eye, Waiting Room, Breakthrough, and Amnesia. Let us dive in!

(Note: The following description assumes that the self-experimenter is in good physical and mental health at the time of consuming the DMT. It is well known that negative states of consciousness can lead to incomprehensible hellscapes when “boosted” by DMT (please avoid DMT at all costs while you are drunk, depressed, angry, suicidal, irritable, etc.). The full geometry is best appreciated on a mentally and emotionally balanced set and settings.)

(1) Threshold

The very first alert of something unusual happening may take between 3 to 30 seconds after inhaling the DMT, depending on the dose consumed. Rather than a clear sensorial or cognitive change, the very first hint is a change in the apparent ambiance of one’s setting. You know how at times when you enter a temple, an art museum, a crowd of people, or even just a well decorated restaurant you can abstract an undefinable yet clearly present “vibe of the place”? There’s nothing overt or specific about it. The ambiance of a place is more of an overall gestalt than a localized feeling. An ambiance somehow encodes information about the social, ideological and aesthetic quality of the place or community you just crashed into, and it tells you at a glance which moods are socially acceptable and which ones are discouraged. The specific DMT vibe you feel on a given session can be one of a million different flavors. That said, whether you feel like you entered a circus or joined a religious ceremony, the very first hint of a DMT experience is nonetheless always (or almost always) accompanied with an overall feeling of significance. The feeling that something important is about to happen or is happening is made manifest by the vibe of the state. This vibe is usually present for at least the first 150 seconds or so of the journey. Interestingly, the change in ambiance is shorter-lived than the trip itself; it seems to go away before the visuals vanish quickly declining once the the peak is over.

Within seconds after the change in ambiance, one feels a sudden sharpening of all the senses. Some people describe this as “upgrading one’s experience to an HD version of it”. The level of detail in one’s experience is increased, yet the overall semantic content is still fairly intact. People say things like: “Reality around me seems more crisp” and “it’s like I’m really grasping my surroundings, you know? fully in tune with the smallest textures of the things around me.” Terence Mckenna described this state as follows: “The air appears to suddenly have been sucked out of the room because all the colors brighten visibly, as though some intervening medium has been removed.”

SONY DSC

On a schedule of repeated small doses (below 4 mg; preferably i.m.) one can stabilize this sharpening of the senses for arbitrarily long periods of time. I am a firm believer that this state (quite apart from the alien experiences on higher doses) can already be recruited for a variety of computational and aesthetic tasks that humans do in this day and age. In particular, the state itself seems to enable grasping complex ideas with many parameters without distorting them, which may be useful for learning mathematics at an accelerated pace. Likewise, the sate increases one’s awareness of one’s surroundings (possibly at the expense of consuming many calories). I find it hard to imagine that artists will not be able to use this state for anything valuable.

(2) The Chrysanthemum

If one ups the dose a little bit and lands somewhere in the range between 4 to 8 mg, one is likely to experience what Terrence McKenna called “the Chrysanthemum”. This usually manifests as a surface saturated with a sort of textured fabric composed of intricate symmetrical relationships, bright colors, shifting edges and shimmering pulsing superposition patterns of harmonic linear waves of many different frequencies.

Depending on the dose consumed one may experience either one or several semi-parallel channels. Whereas a threshold dose usually presents you with a single strong vibe (or ambiance), the Chrysanthemum level often has several competing vibes each bidding for your attention. Here are some examples of what the visual component of this state of consciousness may look like.

The visual component of the Chrysanthemum is often described as “the best screen saver ever“, and if you happen to experience it in a good mood you will almost certainly agree with that description, as it is usually extremelly harmonious, symmetric and beautiful in uncountable ways. No external input can possibly replicate the information density and intricate symmetry of this state; such state has to be endogenously generated as a a sort of harmonic attractor of your brain dynamics.

You can find many replications of Chrysanthemum-level DMT experiences on the internet, and I encourage you to examine their implicit symmetries (this replication is one of my all-times favorite).

In Algorithmic Reduction of Psychedelic States we posited that any one of the 17 wallpaper symmetry groups can be instantiated as the symmetries that govern psychedelic visuals. Unfortunately, unlike the generally slow evolution of usual psychedelic visuals, DMT’s vibrational frequency forces such visuals to evolve at a speed that makes it difficult for most people to spot the implicit symmetry elements that give rise to the overall mathematical structure underneath one’s experience. For this reason it has been difficult to verify that all 17 wallpaper groups are possible in DMT states. Fortunately we were recently able to confirm that this is in fact the case thanks to someone who trained himself to do just this. I.e. detecting symmetry elements in patterns at an outstanding speed.

An anonymous psychonaut (whom we will call researcher A) sent a series of trip report to Qualia Computing detailing the mathematical properties of psychedelic visuals under various substances and dose regimens. A is an experienced psychonaut and a math enthusiast who recently trained himself to recognize (and name) the mathematical properties of symmetrical patterns (such as in works of art or biological organisms). In particular, he has become fluent at naming the symmetries exhibited by psychedelic visuals. In the context of 2D visuals on surfaces, A confirms that the symmetrical textures that arise in psychedelic states can exhibit any one of the 17 wallpaper symmetry groups. Likewise, he has been able to confirm that every possible spherical symmetry group can also be instantiated in one’s mind on these states.

The images below show some examples of the visuals that A has experienced on 2C-B, LSD, 4-HO-MET and DMT (sources: top left, top middle, the rest were made with this service):

The Chrysanthemum level interacts with sensory input in an interesting way: the texture of anything one looks at quickly becomes saturated with nested 2-dimensional symmetry groups. If you took enough DMT to take you to this level and you keep your eyes open and look at a patterned surface (i.e. statistical texture), it will symmetrify beyond recognition. A explains that at this level DMT visuals share some qualities with those of, say, LSD, mescaline, and psilocin. Like other psychedelics, DMT’s Chrysanthemum level can instantiate any 2-dimensional symmetry, yet there are important differences from other psychedelics at this dose range. These include the consistent change in ambiance (already present in threshold doses), the complexity and consistency of the symmetrical relationships (much more dense and whole-experience-consistent than is usually possible with other psychedelics), and the speed (with a control-interruption frequency reaching up to 30 hertz, compared to 10-20 hertz for most psychedelics). Thus, people tend to point out that DMT visuals (at this level) are “faster, smaller, more detailed and more globally consistent” than on comparable levels of alteration from similar agents.

Now, if you take a dose that is a little higher (in the ballpark of 8 to 12 mg), the Chrysanthemum will start doing something new and interesting…

(3) The Magic Eye Level

A great way to understand the Magic Eye level of DMT effects is to think of the Chrysanthemum as the texture of an autostereogram (colloquially described as “Magic Eye” pictures). Our visual experience can be easily decomposed into two points-of-view (corresponding to the feed coming from each eye) that share information in order to solve the depth-map problem in vision. This is to map each visual qualia to a space with relative distances so (a) the input is explained and (b) you get recognizable every-day objects represented as implicit shapes beneath the depth-map. You can think of this process as a sort of hand-shake between bottom-up perception and top-down modeling.

In everyday conditions one solves the depth-map problem within a second of opening one’s eyes (minus minor details that are added as one looks around). But on DMT, the “low-level perceptions” looks like a breathing Chrysanthemum, which means that the top-down modeling has that “constantly shifting” stuff to play with. What to make of it? Anything you can think of.

There are three major components of variance on the DMT Magic Eye level:

  1. Texture (dependent on the Chrysanthemum’s evolution)
  2. World-sheet (non-occluduing 3D1T depth maps)
  3. Extremelly lowered information copying threshold.

The image on the left is a lobster, the one on the center is a cone and the one to the right contains furniture (a lamp, a chair and a table). Notice that what you see is a sort of depth-map which encodes shapes. We will call this depth-map together with the appearance of movement and acceleration represented in it, a world-sheet.

World-Sheets

The world-sheet encodes the “semantic content” of the scene and is capable of representing arbitrary situations (including information about what you are seeing, where you are, what the entities there are doing, what is happening, etc.).

It is common to experience scenes from usually mundane-looking places like ice-cream stores, play pens, household situations, furniture rooms, apparel, etc.. Likewise, one frequently sees entities in these places, but they rarely seem to mind you because their world is fairly self-contained. As if seeing through a window. People often report that the worlds they saw on a DMT trip were all “made of the same thing”. This can be interpreted as the texture becoming the surfaces of the world-sheet, so that the surfaces of the tables, chairs, ice-cream cones, the bodies of the people, and so on are all patterned with the same texture (just as in actual autostereograms). This texture is indeed the Chrysanthemum completely contorted to accommodate all the curvature of the scene.

Magic Eye level scenes often include 3D geometrical shapes like spheres, cones, cylinders, cubes, etc. The complexity of the scene is roughly dose-dependent. As one ups the highness (but still remaining within the Magic Eye level) complex translucid qualia crystals in three dimensions start to become a possibility.

Whatever phenomenal objects you experience on this level that lives for more than a millisecond needs to have effective strategies for surviving in an ecosystem of other objects adapted to that level. Given the extremelly lowered information copying threshold, whatever is good at making copies of itself will begin to tesselate, mutate and evolve, stealing as much of your attention as possible in the way. Cyclic transitions occupy one’s attention: objects quickly become scenes which quickly become gestalts from which a new texture evolves in which new objects are detected and so on ad infinitum.

katoite-hydrogarnet

A reports that at this dose range one can experience at least some of the 230 space groups as objects represented in the world-sheet. For example, A reports having stabilized a structure with a Pm-3m symmetry structure, not unlike the structure of ZIF-71-RHO. Visualizing such complex 3D symmetries, however, does seem to require previous training and high levels of mental concentration (i.e. in order to ensure that all the symmetry elements are indeed what they are supposed to be).

There is so much qualia laying around, though, at times not even your normal space can contain it all. Any regular or semi regular symmetrical structure you construct by focusing on it is prone to overflow if you focus too much on it. What does this mean? If you focus too much on, for example, the number 6, your mind might represent the various ways in which you can arrange six balls in a perfectly symmetrical way. Worlds made of hexagons and octahedrons interlocked in complex but symmetrical ways may begin to tesselate your experiential field. With every second you find more and more ways of representing the number six in interesting, satisfying, metaphorically-sound synesthetic ways (cf. Thinking in Numbers). Now, what happens if you try to represent the number seven in a symmetric way on the plane? Well, the problem is that you will have too many heptagons to fit in Euclidean space (cf. Too Many Triangles). Thus the resulting symmetrical patterns will seem to overflow the plane (which is often felt as a folding and fluid re-arrangement, and when there is no space left in a region it either expands space or it is felt as some sort of synesthetic tension or stress, like a sense of crackling under a lot of pressure).

In particular, A claims that in the lower ranges of the DMT Magic Eye level the texture of the Chrysanthemum tends to exhibit heptagonal and triheptagonal tilings (as shown in the picture above). A explains that at the critical point between the Chrysanthemum and the Magic Eye levels the intensity of the rate of symmetry detection of the Chrysanthemum cannot be contained to a 2D surface. Thus, the surface begins to fold, often in semi-symmetric ways. Every time one “recognizes” an object on this “folding Chrysanthemum” the extra curvature is passed on to this object. As the dose increases, one interprets more and more of this extra curvature and ends up shaping a complex and highly dynamic spatiotemporal depth map with hyperbolic folds. In the upper ranges of the Magic Eye level the world-sheet is so curved that the scenes one visualize are intricate and expansive, feeling at times like one is able to peer through one’s horizon in all directions and see oneself and one’s world from a distance. At some critical point one may feel like the space around one is folding into a huge dome where the walls are made of whatever texture + world-sheet combination happened to win the Darwinian selection pressures applied to the qualia patterns on the Magic Eye level. This concentrated hyperbolic synesthetic texture is what becomes the walls of the Waiting Room…

(4) Waiting Room

In the range of 12-25mg of DMT a likely final destination is the so-called Waiting Room. This experience is distinguished from the Magic Eye level in several ways: first, the world-sheet at this level breaks into several quasi-independent components, each evolving semi-autonomously. Second, one goes from “partial immersion” into “full immersion”. The transition between Magic Eye and Waiting Room often looks like “finding a very complex element in the scene and using it as a window into another dimension”. The total 2D surface curvature present (by adding up the curvature of all elements in the scene) is substantially higher than that of the Magic Eye level, and one can start to see actual 3D hyperbolic space. Perhaps a way of describing this transition is as follows: The curvature of the world-sheet gets to be so extreme that in order to accommodate it one’s entire multi-modal experiential field becomes involved, and a feeling of total and complete synchronization of all senses into a unified synesthetic experience is inescapable (often described as the “mmmMMMMMMM+++++!!!” whole-body tone people report). Thus the feeling of entering into an entirely new dimension. This explains what people mean when they say: “I experienced such an intense pressure that my soul could not be contained in my tiny body, and the intense pressure launched me into a bigger world”.

The images above, taken together, are meant as an impressionistic replication of what a Waiting Room experience may feel like. On the left you see the textured world-sheet curved in several ways resulting in an enclosed room with shimmering walls and an entity looking at a futuristic-looking contraption. The images on the right are meant to illustrate the ways in which the texture of the world-sheet evolves: you will find that the micro-structure of such texture is constantly unfolding in new symmetrical ways (bottom right), and propagating such changes throughout the entire surface at a striking speed (top right).

DMT Waiting Rooms contain entities that at times do interact directly with you. Their reality is perceived as a much more intense and intimate version of what human interaction normally is, but they do not give the impression of being telepathic. That said, their power is felt as if they could radiate it. One could say that this level of DMT places you in such an intimate, vulnerable and open state that interpreting the entities in a second-person social mode is almost inevitable. It is like interacting with someone you really know (or perhaps someone you really really want to know… or really really don’t want to know), except that the whole world is made of those feelings and some entities inhabit that world.

Serious hard-core psychonauts tend to describe the Wating Room as a temporary stopgap. Indeed more poetry could ever be written about the Waiting Room states of consciousness than about most human activities, for its state-space is larger, more diverse and more hedonically loaded. But even so, it is important to realize that there are even weirder states. Serious psychonauts exploring the upper ranges of humanly-accessible high energy consciousness research may see Waiting Rooms as a stepping stones to the real deal…

(5) Breakthrough

If one manages to ingest around 20-30mg of DMT there is a decent chance that one will achieve a DMT breakthrough experience (some sources place the dosage as high as 40mg). There is no agreed-upon definition for a “DMT breakthrough”, but most experienced users confirm that there is a qualitative change in the structure and feel of one’s experience on such high doses. Based on A’s observations we postulate that DMT breakthroughs are the result of a world-sheet with a curvature so extreme that topological bifurcations start to happen uncontrollably. In other words, the very topology of one’s world-sheet is forced to change in order to accommodate all of the intense curvature.

The geometry of space you experience may suddenly go from a simply-connected space into something else. What does this mean? Suddenly one may feel like space itself is twisting and reconnecting to itself in complex (and often confusing) ways. One may find that given any two points on this “alien world” there may be loops between them. This has drastic effects on one’s every representation (including, of course, the self-other divide). The particular feeling that comes with this may explain the presence of PSIS-like experiences induced by DMT and high dose LSD (cf. LSD and Quantum Measurements). Since the topological bifurcations are happening on a 3D1T world-sheet, this may look like “multiple things happening at once” or “objects taking multiple non-overlapping paths at once in order to get from one place into another”. The entities at this level feel transpersonal: due to the extreme curvature it is hard to distinguish between the information you ascribe to your self-model and the information you ascribe to others. Thus one is all over the place, in a literal topological sense.

While on the Waiting Room one can stabilize the context where the experience seems to be taking place, on a DMT breakthrough state one invariably “moves across vast regions, galaxies, universes, realities, etc.” in a constant uncontrollable way. Why is this? This may be related to whether one can contain the curvature of the objects one attends to. If the curvature is uncontrollable, it will “pass on to the walls” and result in constant “context switches”. In fact, such a large fraction of 3D space is perceived as hyperbolic in one way or another, that one seems to have access to vast regions of reality at the same time. Thus a sense of radical openness is often experienced.

(6) Amnesia Level

Unlike 5-MeO-DMT, “normal DMT” experiences are not typically so mind-warping that they dissolve one’s self-model completely. On the contrary, many people report DMT as having “surprisingly little effect on one’s sense of self except at very high doses” relative to the overall intensity of the alteration. Thus, DMT usually does not produce amnesia due to ego death directly. Rather, the amnesic properties of DMT at high doses can be blamed on the difficulty of instantiating the necessary geometry to make sense of what was experienced. In the case of doses above “breakthrough experiences” there is a chance that the user will not be able to recall anything about the most intense periods of the journey. Unfortunately, we are not likely to learn much from these states (that is, until we live in a community of people who can access other phenomenal geometries in a controlled fashion).

Recalling the Immemorial

We postulate that the difficulty people have remembering the phenomenal quality of a DMT experience is in part the result of not being able to access the geometry required to accurately relive their hallucinations. The few and far apart elements of the experience that people do somehow manage to remember, we posit, are those that happen to be (relatively) easy to embed in 3D Euclidean space. Thus, we predict that what people do manage to “bring back” from hyperspace will be biased towards those things that can be represented in R3.

This explains why people remember experiencing intensely saddled scenes (e.g. fractals, tunnels, kale worlds, recursive processes, and so on). Unfortunately most information-rich and interesting (irreducible, prime) phenomenal objects one experiences on DMT are by their very nature impossible to embed in our normal experiential geometry. This problem reveals an intrinsic limitation that comes from living in a community of intelligences (i.e. contemporary humans) who are constrained in the range of state-spaces of consciousness that they can access. This realization calls for a new epistemological paradigm, one that incorporate state-specific representations into a globally accessible database of states of consciousness, together with the network that emerges from their mutual (in)intelligibility.

DMT Objects

The increased curvature of one’s world-sheet can manifest in endless ways. In some important ways, the state-space of possible scenes that you can experience on DMT is much bigger than what you can experience on normal states of consciousness. Strictly speaking, you can represent more scenes on DMT states than in most other states because the overall amount qualia available is much larger. Of course the very dynamics of these experiences constrains what can be experienced, so there are still many things inaccessible on DMT. For instance, it may be impossible to experience a perfectly uniform blue screen (since the Chrysanthemum texture is saturated with edges, surfaces and symmetrical patterns). Likewise, scenes that are too irregular may be impossible to stabilize given the omnipresent symmetry enhancement found in the state.

What are the nature of the objects and entities one experiences on DMT? Magic Eye level experiences tend to include objects that are usually found in our everyday life. It is at the DMT waiting room level and above that the “truly impossible objects” begin to emerge. In particular, all of these objects are often curved in extreme ways. They condense within them complex networks of interlocking structures sustaining an overall superlative curvature. Here are some example objects that one can experience on Waiting Room and Breakthrough level experiences:

Notice that all of these images have many saddles everywhere. Ultimately, the range of objects one can experience on such states includes many other features that are impossible to represent in R3. The objects that people do manage to bring back and recall later on, are precisely those that can be embedded in R3. Thus you often see extremelly contorted wrapped-up objects. The most interesting ones (such as quasi-regular H3 tilings or irreducible objects) are next-to-impossible to bring back in any meaningful way, for now at least.

DMT Space Expansion

The expansion of space responsible for the increased curvature happens anywhere you direct your attention (including the objects you see). Here you can see what it may look like to stare at a DMT object: This is called the “jitterbox” mechanism.

DMT entities

DMT entities come in many forms, and their overall quality is extremelly dose-dependent. Rather than describing any specific manifestation we will instead briefly characterize the rough properties of the entities experienced based on the level reached.

  1. Threshold: Usually the ambiance change has a social feel to is. More similar to entering a room of people of an alien culture, than entering an empty cave or a warm pool on your own. In this sense the very beginning of a DMT experience may already frame the experience in social terms and facilitate the expectation of meeting entities.
  2. Chrysanthemum: One can feel perhaps the subtle presence of entities, but they are often interpreted as “feeling connected” to one’s friends, relatives and acquaintances. The feeling does not manifest in any clear spatial way, though. Other than that, this state is apersonal in the sense that one does not see any entity directly.
  3. Magic Eye: Here the entities can be roughly described as having an impersonal relationship with you. They are just there, hanging out on their own, often engrossed with whatever activities your world-sheet is capable of representing for them.
  4. Waiting Room: At this level entities start becoming able to interact with you. They feel like autonomous beings wrapped in mystery. Their intentions, what they know, and their emotional states can be guessed from their behavior, but they are not immediatly obvious.
  5. Breakthrough: At this level the entities one meets seem to have what we might call a transpersonal relationship with you. They share their own internal states (emotions, knowledge, wishes, etc) with you. It feels like they can communicate telepathically and “see through” you. One cannot hide one’s “private” mental contents from them at this level.
  6. Amnesia: One cannot remember, of course, exactly what happens here. But if trip reports are any indication, this level is reminiscent of highly “mystical” states in which one’s implicit beliefs about Personal Identity are obliterated and replaced by the feeling of becoming an all-encompassing entity. “Union with God” and “Samadhi” are terms that describe the subjective feeling of self in this state. In other words, at this level it is impossible to distinguish between oneself and other entities, for all is represented as one. (Beware of never trying to go here if you feel bad at the time since negative hedonic tone can be amplified just as much as a good feeling such as Samadhi).

Modeling the Hyperbolic Geometry of DMT

How can we explain the drastic geometric changes of phenomenal space on DMT? As mentioned earlier, we will discuss three (non-mutually exclusive) hypothesis. These hypothesis work at the level of an algorithmic reduction, which means that we will go deeper than just describing information processing and phenomenology. We will stop short of addressing the implementation level of abstraction. It is worth pointing out that describing the ways in which DMT experiences are hyperbolic is in itself an algorithmic reduction. What we are about to do is to develop a more granular algorithmic reduction in which we try to explain why hyperbolic geometry emerges on DMT states by postulating underlying processes. Here are the three reductions:

(1) Control Interruption + Symmetry detection = Change in Metric

Recall that on a previous article we algorithmically reduced general psychedelic states. The building blocks of that reduction were:

  1. Control Interruption (which amounts to a “longer half-life for all qualia”)
  2. Drifting (“breathing walls, eyes moving from their normal place, waving sensations”)
  3. Enhanced Pattern Recognition (pareidolia, cf. Getting Closed to Digital LSD)
  4. Lowered Symmetry Detection Threshold (quasi-symmetric patterns tend to “lock into” perfectly symmetrical structures)

Using this framework one can argue that DMT makes space more hyperbolic in the following way: in high amounts the synergistic effect of control interruption together with extremelly lowered symmetry detection thresholds experienced in quick succession makes the subjective distance between the points in the phenomenal objects in the scene evolve a hyperbolic metric. How would this happen? The key thing to realize is that in this model the usual quasi-Euclidean space we experience is an emergent effect of an equilibrium between these two forces. Even in normal circumstances our world-sheet is continuously regenerated; the rate at which symmetrical relationships in the scene are detected is balanced by the rate at which these subjective measurements are forgotten. This usually results in an emergent Euclidean geometry. On DMT the rate of symmetry detection increases while the rate of “forgetting” (inhibiting control) decreases. Attention points out more relationships in quick succession and this creates a network of measured subjective distances that cannot be embedded in Euclidean 3D space. Thus there is an overflow of symmetries. We are currently working on a precise mathematical model of this process in order to reconstruct a hyperbolic metric out of these two parameters. In this model, control interruption is interpreted as a change in the decay for subjective measurements of distance in one’s mind, whereas the lowered symmetry detection threshold is interpreted as a change in the probability of measuring the distance between any two given points as a function of the network of distances already measured.

The curvature increase is most salient where there is already a lot of measurements made, since highly-measured regions focus attention and attention drives symmetry detection. Thus, focusing on any surface will make the surface itself hyperbolic (rather than the 3D space, since measurements are mostly concentrated on the surface). On the other hand, if the curvature is too high to keep on a 2D surface, it will “jump” to 3D or even 3D1T (i.e. branching out the temporal component of one’s experience). The result is that the total curvature of one’s 3D1T world-sheet increases on DMT in a dose-dependent way.

Different doses lead to different states of curvature homeostasis. Each part of the worldsheet has constantly-morphing shapes and sudden curvature changes, but the total curvature is nonetheless more or less preserved on a given dose. It is not easy to get rid of excess curvature. Rather, whenever one tries to reduce the curvature in one part of the scene one is simply pushing it elsewhere. Even when one manages to push most of the curvature out of a given modality (e.g. vision) it is likely to quickly return in another modality (e.g. kinesthetic or auditory landscape) since attention never ceases on a DMT trip. Such apparent dose-dependent global curving of the world-sheet (and its jump from one modality into another) constrains the shape of the objects one can represent on the state (thus leading to alien-looking highly-curved objects similar to the ones shown above).

(2) Dynamic System Account: Energy Sources, Sinks and Invariants

Energy Invariants

Let us define a notion of energy in consciousness so that we can formalize the way experiences warps and transforms on DMT. Assume that one needs “energy” in order to instantiate a given experience (really, this is just an implicit invariant and we could use a different name). Each feature of a given experience needs a certain amount of energy, which roughly corresponds to a weighted sum of the intensity and the information content of an experience. For instance, the brightness of a point of colored light in one’s visual field is energy-dependent. Likewise, the information content in a texture, the number of represented symmetrical relationships, the speed by which an object moves (plus its acceleration), and even the curvature of one’s geometry. All of these features require energy to be instantiated.

Under normal circumstances the brain has many clever and (evolutionarily) appropriate ways of modulating the amount of energy present in different modules of one’s mind. That is, we have many programs that work as energy switches for different mental activities depending on the context. When we think, we have allocated a certain amount of energy to finding a shape/thought-form that satisfies a number of constraints. When it shape-shifting that energy in various ways and finding a solution, we either allocate more energy to it or perhaps give up. However, on DMT the energy cannot be switched off, and it can only pass from one modality into another. In other words, whereas in normal circumstances one uses strategically one’s ability to give energy limits to different tasks, on DMT one simply has constant high energy globally no matter what.

More formally, this model of DMT action says that DMT modifies the structure of one’s mind so that (1) energy freely passes from one form into another, and (2) energy floods the entire system. Let’s talk about energy sources and sinks.

Energy Sources and Sinks

In this algorithmic reduction DMT increases the amount of consciousness in one’s mind by virtue of impairing our normal energy sinks while increasing the throughput of its energy sources. This may frequently manifests as phenomenal spaces becoming hyperbolic in the mathematical-geometric sense of increasing its negative curvature as such curvature is one manifestation of higher levels of energy. Energy sinks are still present and they struggle to capture as much of the energy as possible. In particular, one energy sink is “recognition” of objects on the world-sheet.

This model postulates that attention functions as an energy source, whereas pattern recognition functions as an energy sink.

The Hamiltonian of a World-sheet

The total energy in one’s consciousness increases on DMT, and there is a constant flow between different ways for this energy to take form. That said, one can analyze piecewise the various components of one’s experience, specially if the network of energy exchange clusters well. In particular, we can postulate that world-sheets are fairly self-contained. Relative to other parts of the environment the mind is simulating, the world-sheet itself has a very high within-cluster energy exchange and a relatively low cross-cluster energy exchange. One’s world-sheet is very fluid, and little deformations propagate almost linearly throughout it. In a given dose plateau, if you add up the acceleration, the velocity, the curvature, and so on of every point in the world-sheet you will come up with a number that remains fairly constant over time. Thus studying the Hamiltonian of a world-sheet (i.e. the state-space given by a constant level of energy) can be very informative in describing both the information content and the experiential intensity of DMT experiences.

helicatenoid

You can deform a surface without changing its local curvature. (Source: Gauss’ “Remarkable Theorem” [seriously not my quotes]). Thus on a DMT trip plateau there is still a lot of room for transformations of the world-sheet into different shapes with similar curvature.

Under normal circumstances the curvature of one’s world-sheet is, as far as I can tell, arousal-dependent. Have you noticed how when you feel tired you are more likely to defocus your visual experience? You are tired late at night and you are trying to watch a movie, but bringing the scene in focus is too much of an effort so you defocus for a little bit (still listening to the dialogue). What did you do that for? In the framework here proposed, you did that to diminish the energy it takes you to sustain a curved world-sheet with a lot of information. Doing so may be aesthetically pleasing and rewarding when fully awake or excited, but when tired the returns on doing the focusing are not great given how much effort it needs and the fact that the dialogue is more essential for the plot anyway.

It takes effort and wakefulness to focus on a complex scene with many intricate details. (Reading and trying to comprehend this essay may itself require significant conscious energy expenditure). For this reason we might say that DMT is an exceedingly effective arouser of consciousness.

Bayesian Energy Sinks

One essential property of our minds is that our level of mental arousal decreases when we interpret our experience as “expected”. People who can enjoy their own minds do so, in part, by finding unexpected ways of understanding expected things. In the presence of new information that one cannot easily integrate, however, one’s level of energy is adjusted upwards so that we try out a variety of different models quickly and try to sort out a model that does make the new information expected (though perhaps integrating new assumptions or adding content in other ways). When we cannot manage to generate a mental model that works out a likely model of what we are experiencing we tend to remain in an over-active state.

This general principle applies to the world-sheet. One of the predominant ways in which a world-sheet reduces its energy (locally) is by morphing into something you can recognize or interpret. Thus the world-sheet in some way keeps on producing objects, at first familiar, but in higher energies the whole process can seem desperate or hopeless: one can only recognize things with a stretch of the imagination. Since humans in general lack much experience with hyperbolic geometry, we usually don’t manage to imagine objects that are symmetric on their own native geometry. But when we do, and we fill them up with resonant light-mind-energy, then BAM! New harmonics of consciousness! New varieties of bliss! Music of the angels! OMG! Laughter till infinity and more- shared across the galaxy- in a hyperbolic transpersonal delight! It’s like LSD and N2O! Wow!

Forgive me, it is my first day. Let’s carry on. As one does not know any object that the world-sheet can reasonably be able to generate in high doses, and the world-sheet has so much energy on its own, energy can seem to spiral out of control. This explains in part the non-linear relationship between experienced intensity and DMT dose.

Like all aspects of one’s consciousness, the negative curvature of phenomenal space tends to decay over time (possibly through inhibition by the cortex). In this case, the feeling is one of “smoothing out the curves” and embedding the phenomenal objects in 3D euclidean space. However, this is opposed by the effect that attention and (degrees of) awareness have on our phenomenal sheet, which is to increase its negative curvature. On DMT, anything that attention focuses on will begin branching, copying itself and multiplying, a process that quickly saturates the scene to the point of filling more spatial relationships than would fit in Euclidean 3D. The rate at which this happens is dose-dependent. The higher the dose, the less inhibiting control there is and the more intense the “folding” property of attention will be. Thus, for different dosages one reaches different homeostatic levels of overall curvature in one’s phenomenal space. Since attention does not stop at any point during a DMT trip (it keeps being bright and intense all throughout) there isn’t really any rest period to sit back and see the curvature get smoothed out on its own. Everything one thinks about, perceives or imagines branches out and bifurcate at a high speed.

Every moment during the experience is very hard to “grasp” because the way one normally does that in usual circumstances is by focusing attention on it and shaping one’s world-sheet to account for the input. But here that very attention makes the world-sheet wobble, warp and expand beyond recognition. Thus one might say that during a solid DMT experience one never sees the same thing twice, as the experience continues to evolve. That is, of course, as long as you do not stumble upon (or deliberatively create) stable phenomenal objects whose structure can survive the warping effect of attention.

(3) Hyperbolic Micro-structure of Consciousness

Subjectively, A says, negative curvature is associated with more energy. Perhaps this curvature happens at a very low level? An example to light up the imagination is using heat to fold a sheet of metal (thanks to thermal expansion). Whatever your attention focuses on seems to get heated up (in some sense) and expand as a result. The folding patterns themselves seem to store potential energy. Left on their own, this extra energy stored as negative curvature usually dissipates, but on DMT this process is lowered (while the effect of increasing the energy is heightened). Could this be the result of some very very fine-level micro-experiential change that gradually propagates upwards? With the help of our normal mental processes the change in the micro-structure may propagate all the way into seemingly hyperbolic 2D and 3D surfaces.

Perhaps the most important difference between DMT in high doses and other psychedelics is that the micro-structure of consciousness drifts in such a way that tiny Droste effects bubble up into large Möbius transforms.

As noted already, these three algorithmic reductions are not incompatible. We just present them here due to their apparent explanatory power. A lot more theoretical work will be needed to make them quantitative and precise, but we are optimistic. The aim is now to develop an experimental framework to distinguish between the predictions that each candidate algorithmic reduction makes (including many not presented here). This is a work in progress.

Generalizing hyperbolization to non-spatial experiential fields

In the case of experiential fields such as body feelings, smells and concepts, the “hyperbolization” takes different forms depending on the algorithmic reduction you use. I prefer the very general interpretation that one experiences hyperbolic information geometry rather than just hyperbolic space. In other words, when we talk about body feelings and so on, on a psychedelic one organizes such information in a hyperbolic relational graph, which also exhibits a negative curvature relative to its normal geometry. Arguing in favor of this interpretation would take another article, so we will leave that for another time.

Getting a handle on the DMT state

Gluing a 1-handle is easy on a 2-sphere. Tongue in cheek, sticking a little doughnut on a big ball allows you to grab the sphere and control it in some way. But how do you get a handle on hyperbolic space? The answer is to build hyperbolic manifolds at the core of one’s being, by imagining knots very intensely. The higher one is, the more complex the knot one can imagine in detail. Having practiced visualizations of this sort while sober certainly helps. If you imagine the knot with enough detail, you can then stress the environment surrounding it to represent a warped hyperbolic space. This way you give life to the complement of the knot (which is almost always hyperbolic!). We postulate that it is possible to study in detail the relationship between the knots imagined, and the properties of the experiential worlds that result from their inversion (i.e. thinking about the geometry of the space surrounding the knot rather than the knot itself). A reports that different hyperbolic spaces generated this way (i.e. imagining knots on tryptamines) have different levels of energy, and have unique resonant properties. Different kinds of music feel better in different kinds of hyperbolic manifolds. It takes more energy to “light up” a hyperbolic space like that, mostly due to its openness. This is why using small doses of 2C-B can be helpful to create a positive backbone to the experience (providing the necessary warmth to light up the hyperbolic space). Admittedly MDMA tends to work best, but its use is unadvisable for reasons we will not get into (related to the hedonic treadmill). A healthy combination that both enables the visualization of the hyperbolic spaces in a vivid way and also lights them up with positive hedonic tone healthily and reliably has yet to be found.

Relatedly… Get a handle on your DMT trip by creating a stabilizing 4D hyperbolic manifold in four easy steps:

Unifying Your Space

God, the divine, open individualism, the number one, an abstract notion of self, or the thought of existence itself are all thoughts that work as great “unifiers” of large areas of phenomenal space. Indeed these concepts can allow a person to connect the edges of the hyperbolic space and create a pocket of one’s experience that does not seem to have a boundary yet is extremelly open. This may be a reason why such ideas are very common in high levels of psychedelia. In a sense, depending on the mind, they have at times the highest recruiting power for your multi-threaded attention.

Applications to Qualia Computing and Closing Thoughts

Beyond mere designer synesthesia, the future of consciousness research contains the possibility of exploring alternative geometries for the layout of our experiences. One’s overall level of energy, its manifestation, the allowed invariants, the logic gates, the differences in resonance, the granularity of the patterns, and so on, are all parameters that we will get to change in our minds to see what happens (in controlled and healthy ways, of course). The exploration of the state-space of consciousness is sure to lead to a combinatorial explosion. Even with good post-theoretical quantitative algorithmic reductions, it is likely that qualia computing scientists will still find an unfathomable number of distinct “prime” permutations. For some applications it may be more useful to use special kinds of hyperbolic spaces (like the compliment of certain class of knot), but for others it may suffice to be a little sphere. Who knows. In the end, if a valence economy ends up dominating the world, then the value of hyperbolic phenomenal spaces will be proportional to the level of wellbeing and bliss that can be felt in them. Which space in which resonant mode generates the highest level of bliss? This is an empirical question with far-reaching economic implications.

Mathematics post-hyperbolic consciousness

I predict that some time in the next century or so many of the breakthroughs in mathematics will take place in consciousness research centers. The ability to utilize arbitrary combinations of qualia with programable geometry and information content (in addition to our whole range of pre-existing cognitive skills) will allow people to have new semantic primitives related to mathematical structures and qualia systems currently unfathomable to us. In the end, studying the mathematics of consciousness and valence is perhaps the ultimate effective altruist endeavor in a world filled with suffering, since reverse-engineering valence would simplify paradise engineering… But even in a post-scarcity world, consciousness research will also probably be the ultimate past time given the endless new discoveries awaiting to be found in the state-space of consciousness.


*On the unexpected side effects of staring at a cauliflower on DMT: You can get lost in the hyperbolic reality of the (apparent) life force that spirals in a scale-free fractal fashion throughout the plant. The spirals may feel like magnetic vortexes that take advantage of your state to attract your attention. The cauliflower may pull you into its own world of interconnected fractals, and as soon as you start to trust it, it begins trying to recruit you for the cauliflower cause. The cauliflower may scare you into not eating it, and make you feel guilty about frying it. You may freak out a little, but when you come down you convince yourself that it was all just a hallucination. That said, you secretly worry it was for real. You may never choose to abstain from eating cauliflowers, but you will probably drop the knife when cooking it. You will break it apart with your own hands in the way you think minimizes its pain. You sometimes wonder whether it experiences agony as it is slowly cooked in the pan, and you drink alcohol to forget. Damn, don’t stare at a cauliflower while high on DMT if you ever intend to eat one again.

P.S. Note on Originality: The only mention I have been able to find that explicitly connects hyperbolic geometry in a literal sense with DMT (rather than just metaphorical talk of “hyperspace”) is a 2014 post in the Psychonaut subredit. To my knowledge, no one has yet elaborated to any substantial degree on this interesting connection. That said, I’m convinced that during the days that follow a strong trip, psychedelic self-experimenters may frequently wonder about the geometry of the places they explored. Yet they usually lack any conceptual framework to justify their intuitions or even verbalize them, so they quickly forget about them.

P.S.S. Example Self-Dribbling Basketball:

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Self-dribbling basketball

To the right you can see what a “self-dribbling basketball” looks like. The more you try to “grasp” what it is, the more curved it gets. That’s because you are adding energy with you attention and you do not have enough recognition ability in this space to lower its energy and reduce the curvature to stabilize it. The curvature is so extreme at times that it produces constant “context switches”. This is the result of excess curvature being pushed towards the edge of your experience and turning into walls and corridors.

P.S.S.S.: Example on world-sheet bending:

Below you can find two gifs that illustrate the behavior of a world-sheet on a 5mg vs. 20mg dose. The speed at which you are adding curvature to it increases so much that the shapes and objects keep shifting to accommodate it all.

(Source of super-trippy symmetric hyperbolic manifold representations: http://newearthlovelight.tumblr.com/post/70053311720)