QRI’s FAQ

These are the answers to the most Frequently Asked Questions about the Qualia Research Institute. (See also: the glossary).


(Organizational) Questions About the Qualia Research Institute

  • What type of organization is QRI?

    • QRI is a nonprofit research group studying consciousness based in San Francisco, California. We are a registered 501(c)(3) organization.

  • What is the relationship between QRI, Qualia Computing, and Opentheory?

    • Qualia Computing and Opentheory are the personal blogs of QRI co-founders Andrés Gómez Emilsson and Michael Johnson, respectively. While QRI was in its early stages, all original QRI research was initially published on these two platforms. However, from August 2020 onward, this is shifting to a unified pipeline centered on QRI’s website.

  • Is QRI affiliated with an academic institution or university?

    • Although QRI does collaborate regularly with university researchers and laboratories, we are an independent research organization. Put simply, QRI is independent because we didn’t believe we could build the organization we wanted and needed to build within the very real constraints of academia. These constraints include institutional pressure to work on conventional projects, to optimize for publication metrics, and to clear various byzantine bureaucratic hurdles. It also includes professional and social pressure to maintain continuity with old research paradigms, to do research within an academic silo, and to pretend to be personally ignorant of altered states of consciousness. It’s not that good research cannot happen under these conditions, but we believe good consciousness research happens despite the conditions in academia, not because of them, and the best use of resources is to build something better outside of them.

  • How does QRI align with the values of EA?

    • Effective Altruism (EA) is a movement that uses evidence and reason to figure out how to do the most good. QRI believes this aesthetic is necessary and important for creating a good future. We also believe that if we want to do the most good, foundational research on the nature of the good is of critical importance. Two frames we offer are Qualia Formalism and Sentientism. Qualia Formalism is the claim that experience has a precise mathematical description, that a formal account of experience should be the goal of consciousness research. Sentientism is the claim that value and disvalue are entirely expressed in the nature and quality of conscious experiences. We believe EA is enriched by both Qualia Formalism and Sentientism.

  • What would QRI do with $10 billion?

    • Currently, QRI is a geographically distributed organization with access to commercial-grade neuroimaging equipment. The first thing we’d do with $10 billion is set up a physical headquarters for QRI and buy professional-grade neuroimaging devices (fMRI, MEG, PET, etc.) and neurostimulation equipment. We’d also hire teams of full-time physicists, mathematicians, electrical engineers, computer scientists, neuroscientists, chemists, philosophers, and artists. We’ve accomplished a great deal on a shoestring budget, but it would be hard to overestimate how significant being able to build deep technical teams and related infrastructure around core research threads would be for us (and, we believe, for the growing field of consciousness research). Scaling is always a process and we estimate our ‘room for funding’ over the next year is roughly ~$10 million. However, if we had sufficiently deep long-term commitments, we believe we could successfully scale both our organization and research paradigm into a first-principles approach for decisively diagnosing and curing most forms of mental illness. We would continue to run studies and experiments, collect interesting data about exotic and altered states of consciousness, pioneer new technologies that help eliminate involuntary suffering, and develop novel ways to enable conscious beings to safely explore the state-space of consciousness.

Questions About Our Research Approach

  • What differentiates QRI from other research groups studying consciousness?

    • The first major difference is that QRI breaks down “solving consciousness” into discrete subtasks; we’re clear about what we’re trying to do, which ontologies are relevant for this task, and what a proper solution will look like. This may sound like a small thing, but an enormous amount of energy is wasted in philosophy by not being clear about these things. This lets us “actually get to work.”

    • Second, our focus on valence is rare in the field of consciousness studies. A core bottleneck in understanding consciousness is determining what its ‘natural kinds’ are: terms which carve reality at the joints. We believe emotional valence (the pleasantness/unpleasantness of an experience) is one such natural kind, and this gives us a huge amount of information about phenomenology. It also offers a clean bridge for interfacing with (and improving upon) the best neuroscience.

    • Third, QRI takes exotic states of consciousness extremely seriously whereas most research groups do not. An analogy we make here is that ignoring exotic states of consciousness is similar to people before the scientific enlightenment thinking that they can understand the nature of energy, matter, and the physical world just by studying it at room temperature while completely ignoring extreme states such as what’s happening in the sun, black holes, plasma, or superfluid helium. QRI considers exotic states of consciousness as extremely important datapoints for reverse-engineering the underlying formalism for consciousness.

    • Lastly, we have a focus on precise, empirically testable predictions, which is rare in philosophy of mind. Any good theory of consciousness should also contribute to advancements in neuroscience. Likewise, any good theory of neuroscience should contribute to novel, bold, falsifiable predictions, and blueprints for useful things, such as new forms of therapy. Having such a full-stack approach to consciousness which does each of those two things is thus an important marker that “something interesting is going on here” and is simply very useful for testing and improving theory.

  • What methodologies are you using? How do you actually do research? 

    • QRI has three core areas of research: philosophy, neuroscience, and neurotechnology 

      • Philosophy: Our philosophy research is grounded in the eight problems of consciousness. This divide-and-conquer approach lets us explore each subproblem independently, while being confident that when all piecemeal solutions are added back together, they will constitute a full solution to consciousness.

      • Neuroscience: We’ve done original synthesis work on combining several cutting-edge theories of neuroscience (the free energy principle, the entropic brain, and connectome-specific harmonic waves) into a unified theory of Bayesian emotional updating; we’ve also built the world’s first first-principles method for quantifying emotional valence from fMRI. More generally, we focus on collecting high valence neuroimaging datasets and developing algorithms to analyze, quantify, and visualize them. We also do extensive psychophysics research, focusing on both the fine-grained cognitive-emotional effects of altered states, and how different types of sounds, pictures, body vibrations, and forms of stimulation correspond with low and high valence states of consciousness.

      • Neurotechnology: We engage in both experimentation-driven exploration, tracking the phenomenological effects of various interventions, as well as theory-driven development. In particular, we’re prototyping a line of neurofeedback tools to help treat mental health disorders.

  • What does QRI hope to do over the next 5 years? Next 20 years?

    • Over the next five years, we intend to further our neurotechnology to the point that we can treat PTSD (post-traumatic stress disorder), especially treatment-resistant PTSD. We intend to empirically verify or falsify the symmetry theory of valence. If it is falsified, we will search for a new theory that ties together all of the empirical evidence we have discovered. We aim to create an Effective Altruist cause area regarding the reduction of intense suffering as well as the study of very high valence states of consciousness.

    • Over the next 20 years, we intend to become a world-class research center where we can put the discipline of “paradise engineering” (as described by philosopher David Pearce) on firm academic grounds.

Questions About Our Mission

  • How can understanding the science of consciousness make the world a better place?

    • Understanding consciousness would improve the world in a tremendous number of ways. One obvious outcome would be the ability to better predict what types of beings are conscious—from locked-in patients to animals to pre-linguistic humans—and what their experiences might be like.

    • We also think it’s useful to break down the benefits of understanding consciousness in three ways: reducing the amount of extreme suffering in the world, increasing the baseline well-being of conscious beings, and achieving new heights for what conscious states are possible to experience.

    • Without a good theory of valence, many neurological disorders will remain completely intractable. Disorders such as fibromyalgia, complex regional pain syndrome (CRPS), migraines, and cluster headaches are all currently medical puzzles and yet have incredibly negative effects on people’s livelihoods. We think that a mathematical theory of valence will explain why these things feel so bad and what the shortest path for getting rid of them looks like. Besides valence-related disorders, nearly all mental health disorders, from clinical depression and PTSD to schizophrenia and anxiety disorders, will become better understood as we discover the structure of conscious experience.

    • We also believe that many (though not all) of the zero-sum games people play are the products of inner states of dissatisfaction and suffering. Broadly speaking, people who have a surplus of cognitive and emotional energy tend to play more positive sum games, are more interested in cooperation, and are very motivated to do so. We think that studying states such as those induced by MDMA that combine both high valence and a prosocial behavior mindset can radically alter the game theoretical landscape of the world for the better.

  • What is the end goal of QRI? What does QRI’s perfect world look like?

    • In QRI’s perfect future:

      • There is no involuntary suffering and all sentient beings are animated by gradients of bliss,

      • Research on qualia and consciousness is done at a very large scale for the purpose of mapping out the state-space of consciousness and understanding its computational and intrinsic properties (we think that we’ve barely scratched the surface of knowledge about consciousness),

      • We have figured out the game-theoretical subtleties in order to make that world dynamic yet stable: radically positive, without just making it fully homogeneous and stuck in a local maxima.

Questions About Getting Involved

  • How can I follow QRI’s work?

    • You can start by signing up for our newsletter! This is by far our most important communication channel. We also have a Facebook page, Twitter account, and Linkedin page. Lastly, we share some exclusive tidbits of ideas and thoughts with our supporters on Patreon.

  • How can I get involved with QRI?

    • The best ways to help QRI are to:

      • Donate to help support our work.

      • Read and engage with our research. We love critical responses to our ideas and encourage you to reach out if you have an interesting thought!

      • Spread the word to friends, potential donors, and people that you think would make great collaborators with QRI.

      • Check out our volunteer page to find more detailed ways that you can contribute to our mission, from independent research projects to QRI content creation.

Questions About Consciousness

  • What assumptions about consciousness does QRI have? What theory of consciousness does QRI support?

    • The most important assumption that QRI is committed to is Qualia Formalism, the hypothesis that the internal structure of our subjective experience can be represented precisely by mathematics. We are also Valence Realists: we believe valence (how good or bad an experience feels) is a real and well-defined property of conscious states. Besides these positions, we are fairly agnostic and everything else is an educated guess useful for pragmatic purposes.

  • What does QRI think of functionalism?

    • QRI thinks that functionalism takes many high-quality insights about how systems work and combines them in such a way that both creates confusion and denies the possibility of progress. In its raw, unvarnished form, functionalism is simply skepticism about the possibility of Qualia Formalism. It is simply a statement that “there is nothing here to be formalized; consciousness is like élan vital, confusion to be explained away.” It’s not actually a theory of consciousness; it’s an anti-theory. This is problematic in at least two ways:

      • 1. By assuming consciousness has formal structure, we’re able to make novel predictions that functionalism cannot (see e.g. QRI’s Symmetry Theory of Valence, and Quantifying Bliss). A few hundred years ago, there were many people who doubted that electromagnetism had a unified, elegant, formal structure, and this was a reasonable position at the time. However, in the age of the iPhone, skepticism that electricity is a “real thing” that can be formalized is no longer reasonable. Likewise, everything interesting and useful QRI builds using the foundation of Qualia Formalism stretches functionalism’s credibility thinner and thinner.

      • 2. Insofar as functionalism is skeptical about the formal existence of consciousness, it’s skeptical about the formal existence of suffering and all sentience-based morality. In other words, functionalism is a deeply amoral theory, which if taken seriously dissolves all sentience-based ethical claims. This is due to there being an infinite number of functional interpretations of a system: there’s no ground-truth fact of the matter about what algorithm a physical system is performing, about what information-processing it’s doing. And if there’s no ground-truth about which computations or functions are present, but consciousness arises from these computations or functions, then there’s no ground-truth about consciousness, or things associated with consciousness, like suffering. This is a strange and subtle point, but it’s very important. This point alone is not sufficient to reject functionalism: if the universe is amoral, we shouldn’t hold a false theory of consciousness in order to try to force reality into some ethical framework. But in debates about consciousness, functionalists should be up-front that functionalism and radical moral anti-realism is a package deal, that inherent in functionalism is the counter-intuitive claim that just as we can reinterpret which functions a physical system is instantiating, we can reinterpret what qualia it’s experiencing and whether it’s suffering.

    • For an extended argument, see Against Functionalism.

  • What does QRI think of panpsychism?

    • At QRI, we hold a position that is close to dual-aspect monism or neutral monism, which states that the universe is composed of one kind of thing that is neutral, and that both the mental and physical are two features of this same substance. One of the motivating factors for holding this view is that if there is deep structure in the physical, then there should be a corresponding deep structure to phenomenal experience. And we can tie this together with physicalism in the sense that the laws of physics ultimately describe fields of qualia. While there are some minor disagreements between dual-aspect monism and panpsychism, we believe that our position mostly fits well with a panpsychist view—that phenomenal properties are a fundamental feature of the world and aren’t spontaneously created only when a certain computation is being performed.

    • However, even with this view, there still are very important questions, such as: what makes a unified conscious experience? Where does one experience end and another begin? Without considering these problems in the light of Qualia Formalism, it is easy to tie animism into panpsychism and believe that inanimate objects like rocks, sculptures, and pieces of wood have spirits or complex subjective experiences. At QRI, we disagree with this and think that these types of objects might have extremely small pockets of unified conscious experience, but will mostly be masses of micro-qualia that are not phenomenally bound into some larger experience.

  • What does QRI think of IIT (Integrated Information Theory)?

    • QRI is very grateful for IIT because it is the first mainstream theory of consciousness that satisfies a Qualia Formalist account of experience. IIT says (and introduced the idea!) that for every conscious experience, there is a corresponding mathematical object such that the mathematical features of that object are isomorphic to the properties of the experience. QRI believes that without this idea, we cannot solve consciousness in a meaningful way, and we consider the work of Giulio Tononi to be one of our core research lineages. That said, we are not in complete agreement with the specific mathematical and ontological choices of IIT, and we think it may be trying to ‘have its cake and eat it too’ with regard to functionalism vs physicalism. For more, see Sections III-V of Principia Qualia.

    • We make no claim that some future version of IIT, particularly something more directly compatible with physics, couldn’t cleanly address our objections, and see a lot of plausible directions and promise in this space.

  • What does QRI think of the free energy principle and predictive coding?

    • On our research lineages page, we list the work of Karl Friston as one of QRI’s core research lineages. We consider the free energy principle (FEP), as well as related research such as predictive coding, active inference, the Bayesian brain, and cybernetic regulation, as an incredibly elegant and predictive story of how brains work. Friston’s idea also forms a key part of the foundation for QRI’s theory of brain self-organization and emotional updating, Neural Annealing.

    • However, we don’t think that the free energy principle is itself a theory of consciousness, as it suffers from many of the shortcomings of functionalism: we can tell the story about how the brain minimizes free energy, but we don’t have a way of pointing at the brain and saying *there* is the free energy! The FEP is an amazing logical model, but it’s not directly connected to any physical mechanism. It is a story that “this sort of abstract thing is going on in the brain” without a clear method of mapping this abstract story to reality.

    • Friston has supported this functionalist interpretation of his work, noting that he sees consciousness as a process of inference, not a thing. That said, we are very interested in his work on calculating the information geometry of Markov blankets, as this could provide a tacit foundation for a formalist account of qualia under the FEP. Regardless of this, though, we believe Friston’s work will play a significant role in a future science of mind.

  • What does QRI think of global workspace theory?

    • The global workspace theory (GWT) is a cluster of empirical observations that seem to be very important for understanding what systems in the brain contribute to a reportable experience at a given point in time. The global workspace theory is a very important clue for answering questions of what philosophers call Access Consciousness, or the aspects of our experience on which we can report.

    • However, QRI does not consider the global workspace theory to be a full theory of consciousness. Parts of the brain that are not immediately contributing to the global workspace may be composed of micro qualia, or tiny clusters of experience. They’re obviously impossible to report on, but they are still relevant to the study of consciousness. In other words, just because a part of your brain wasn’t included in the instantaneous global workspace, doesn’t mean that it can’t suffer or it can’t experience happiness. We value global workspace research because questions of Access Consciousness are still very critical for a full theory of consciousness.

  • What does QRI think of higher-order theories of consciousness?

    • QRI is generally opposed to theories of consciousness that equate consciousness with higher order reflective thought and cognition. Some of the most intense conscious experiences are pre-reflective or unreflective such as blind panic, religious ecstasy, experiences of 5-MeO-DMT, and cluster headaches. In these examples, there is not much reflectivity nor cognition going on, yet they are intensely conscious. Therefore, we largely reject any attempt to define consciousness with a higher-order theory.

  • What is the relationship between evolution and consciousness?

    • The relationship between evolution and consciousness is very intricate and subtle. An eliminativist approach arrives at the simple idea that information processing of a certain type is evolutionarily advantageous, and perhaps we can call this consciousness. However, with a Qualia Formalist approach, it seems instead that the very properties of the mathematical object isomorphic to consciousness can play key roles (either causal or in terms of information processing) that make it advantageous for organisms to recruit consciousness.

    • If you don’t realize that consciousness maps onto a mathematical object with properties, you may think that you understand why consciousness was recruited by natural selection, but your understanding of the topic would be incomplete. In other words, to have a full understanding of why evolution recruited consciousness, you need to understand what advantages the mathematical object has. One very important feature of consciousness is its capacity for binding. For example, the unitary nature of experience—the fact that we can experience a lot of qualia simultaneously—may be a key feature of consciousness that accelerates the process of finding solutions to constraint satisfaction problems. In turn, evolution would hence have a reason to recruit states of consciousness for computation. So rather than thinking of consciousness as identical with the computation that is going on in the brain, we can think of it as a resource with unique computational benefits that are powerful and dynamic enough to make organisms that use it more adaptable to their environments.

  • Does QRI think that animals are conscious?

    • QRI thinks there is a very high probability that every animal with a nervous system is conscious. We are agnostic about unified consciousness in insects, but we consider it very likely. We believe research on animal consciousness has relevance when it comes to treating animals ethically. Additionally, we do think that the ethical importance of consciousness has more to do with the pleasure-pain axis (valence), rather than cognitive ability. In that sense, the suffering of non-human animals may be just as morally relevant, if not more relevant than humans. The cortex seems to play a largely inhibitory role for emotions, such that the larger the cortex is, the better we’re able to manage and suppress our emotions. Consequently, animals whose cortices are less developed than ours may experience pleasure and pain in a more intense and uncontrollable way, like a pre-linguistic toddler.

  • Does QRI think that plants are conscious?

    • We think it’s very unlikely that plants are conscious. The main reason is that they lack an evolutionary reason to recruit consciousness. Large-scale phenomenally bound experience may be very energetically expensive, and plants don’t have much energy to spare. Additionally, plants have thick cellulose walls that separate individual cells, making it very unlikely that plants can solve the binding problem and therefore create unified moments of experience.

  • Why do some people seek out pain?

    • This is a very multifaceted question. As a whole, we postulate that in the vast majority of cases, when somebody may be nominally pursuing pain or suffering, they’re actually trying to reduce internal dissonance in pursuit of consonance or they’re failing to predict how pain will actually feel. For example, when a person hears very harsh music, or enjoys extremely spicy food, this can be explained in terms of either masking other unpleasant sensations or raising the energy parameter of experience, the latter of which can lead to neural annealing: a very pleasant experience that manifests as consonance in the moment.

  • I sometimes like being sad. Is QRI trying to take that away from me?

    • Before we try to ‘fix’ something, it’s important to understand what it’s trying to do for us. Sometimes suffering leads to growth; sometimes creating valuable things involves suffering. Sometimes, ‘being sad’ feels strangely good. Insofar as suffering is doing good things for us, or for the world, QRI advocates a light touch (see Chesterton’s fence). However, we also suggest two things:

      • 1. Most kinds of melancholic or mixed states of sadness usually are pursued for reasons that cash out as some sort of pleasure. Bittersweet experiences are far more preferable than intense agony or deep depression. If you enjoy sadness, it’s probably because there’s an aspect of your experience that is enjoyable. If it were possible to remove the sad part of your experience while maintaining the enjoyable part of it, you might be surprised to find that you prefer this modified experience more than the original one.

      • 2. There are kinds of sadness and suffering that are just bad, that degrade us as humans, and would be better to never feel. QRI doesn’t believe in forcibly taking away voluntary suffering, or pushing bliss on people. But we would like to live in a world where people can choose to avoid such negative states, and on the margin, we believe it would be better for humanity for more people to be joyful, filled with a deep sense of well-being.

  • If dissonance is so negative, why is dissonance so important in music?

    • When you listen to very consonant music or consonant tones, you will quickly adapt to these sounds and get bored of them. This has nothing to do with consonance itself being unpleasant and everything to do with learning in the brain. Whenever you experience the same stimuli repeatedly, most brains will trigger a boredom mechanism and add dissonance of its own in order to make you enjoy the stimuli less or simply inhibit it, not allowing you to experience it at all. Semantic satiation is a classic example of this where repeating the same word over and over will make it lose its meaning. For this reason, to trigger many high valence states of consciousness consecutively, you need contrast. In particular, music works with gradients of consonance and dissonance, and in most cases, moving towards consonance is what feels good rather than the absolute value of consonance. Music tends to feel the best when you mix a high absolute value of consonance together with a very strong sense of moving towards an even higher absolute value of consonance. Playing some levels of dissonance during a song will later enhance the enjoyment of the more consonant parts such as the chorus of songs, which are reported to be the most euphoric parts of song and typically are extremely consonant.

  • What is QRI’s perspective on AI and AI safety research?

    • QRI thinks that consciousness research is critical for addressing AI safety. Without a precise way of quantifying an action’s impact on conscious experiences, we won’t be able to guarantee that an AI system has been programmed to act benevolently. Also, certain types of physical systems that perform computational tasks may be experiencing negative valence without any outside observer being aware of it. We need a theory of what produces unpleasant experiences to avoid inadvertently creating superintelligences that suffer intensely in the process of solving important problems or accidentally inflict large-scale suffering.

    • Additionally, we think that a very large percentage of what will make powerful AI dangerous is that the humans programming these machines and using these machines may be reasoning from states of loneliness, resentment, envy, or anger. By discovering ways to help humans transition away from these states, we can reduce the risks of AI by creating humans that are more ethical and aligned with consciousness more broadly. In short: an antidote for nihilism could lead to a substantial reduction in existential risk.

    • One way to think about QRI and AI safety is that the world is building AI, but doesn’t really have a clear, positive vision of what to do with AI. Lacking this, the default objective becomes “take over the world.” We think a good theory of consciousness could and will offer new visions of what kind of futures are worth building—new Schelling points that humanity (and AI researchers) could self-organize around.

  • Can digital computers implementing AI algorithms be conscious?

    • QRI is agnostic about this question. We have reasons to believe that digital computers in their current form cannot solve the phenomenal binding problem. Most of the activity in digital computers can be explained in a stepwise fashion in terms of localized processing of bits of information. Because of this, we believe that current digital computers could be creating fragments of qualia, but are unlikely to be creating strongly globally bound experiences. So, we consider the consciousness of digital computers unlikely, although given our current uncertainty over the Binding Problem (or alternatively framed, the Boundary Problem), this assumption is lightly held. In the previous question, when we write that “certain types of physical systems that perform computational tasks may be experiencing negative valence”, we assume that these hypothetical computers have some type of unified conscious experience as a result of having solved the phenomenal binding problem. For more on this topic, see: “What’s Out There?

  • How much mainstream recognition has QRI’s work received, either for this line of research or others? Has it published in peer-reviewed journals, received any grants, or garnered positive reviews from other academics?

    • We are collaborating with researchers from Johns Hopkins University and Stanford University on several studies involving the analysis of neuroimaging data of high-valence states of consciousness. Additionally, we are currently preparing two publications for peer-reviewed journals on topics from our core research areas. Michael Johnson will be presenting at this year’s MCS seminar series, along with Karl Friston, Anil Seth, Selen Atasoy, Nao Tsuchiya, and others; Michael Johnson, Andrés Gómez Emilsson, and Quintin Frerichs have also given invited talks at various east-coast colleges (Harvard, MIT, Princeton, and Dartmouth).

    • Some well-known researchers and intellectuals that are familiar and think positively about our work include: Robin Carhart-Harris, Scott Alexander, David Pearce, Steven Lehar, Daniel Ingram, and more. Scott Alexander acknowledged that QRI put together the paradigms that contributed to Friston’s integrative model of how psychedelics work before his research was published. Our track record so far has been to foreshadow (by several years in advance) key discoveries later proposed and accepted in mainstream academia. Given our current research findings, we expect this trend to continue in the years to come.

Miscellaneous

  • How does QRI know what is best for other people/animals? What about cultural relativism?

    • We think that, to a large extent, people and animals work under the illusion that they are pursuing intentional objects, states of the external environment, or relationships that they may have with the external environment. However, when you examine these situations closely, you realize that what we actually pursue are states of high valence triggered by external circumstances. There may be evolutionary and cultural selection pressures that push us toward self-deception as to how we actually function. And we consider it negative to have these selection pressures makes us less self-aware because it often focuses our energy on unpleasant, destructive, or fruitless strategies. QRI hopes to support people in fostering more self-awareness, which can come through experiments with one’s own consciousness, like meditation, as well as through the deeper theoretical understanding of what it is that we actually want.

  • How central is David Pearce’s work to the work of the QRI?

    • We consider David Pearce to be one of our core lineages. We particularly value his contribution to valence realism, the insistence that states of consciousness come with an overall valence, and that this is very morally relevant. We also consider David Pearce to be very influential in philosophy of mind; Pearce, for instance, coined the phrase ‘tyranny of the intentional object’, the title of a core QRI piece of the same name. We have been inspired by Pearce’s descriptions for what any scientific theory of consciousness should be able to explain, as well as his particular emphasis on the binding problem. David’s vision of a world animated by ‘gradients of bliss’ has also been very generative as a normative thought experiment which integrates human and non-human well-being. We do not necessarily agree with all of David Pearce’s work, but we respect him as an insightful and vivid thinker who has been brave enough to actually take a swing at describing utopia and who we believe is far ahead of his time.

  • What does QRI think of negative utilitarianism?

    • There’s general agreement within QRI that intense suffering is an extreme moral priority, and we’ve done substantial work on finding simple ways of getting rid of extreme suffering (with our research inspiring at least one unaffiliated startup to date). However, we find it premature to strongly endorse any pre-packaged ethical theory, especially because none of them are based on any formalism, but rather an ungrounded concept of ‘utility’. The value of information here seems enormous, and we hope that we can get to a point where the ‘correct’ ethical theory may simply ‘pop out of the equations’ of reality. It’s also important to highlight the fact that common versions and academic formulations of utilitarianism seem to be blind to many subtleties concerning valence. For example, they do not distinguish between mixed states of consciousness where you have extreme pleasure combined with extreme suffering in such a way that you judge the experience to be neither entirely suffering nor entirely happiness and states of complete neutrality, such as extreme white noise. Because most formulations of utilitarianism do not distinguish between them, we are generally suspicious of the idea that philosophers of ethics have considered all of the relevant attributes of consciousness in order to make accurate judgments about morality.

  • What does QRI think of philosophy of mind departments?

    • We believe that the problems that philosophy of mind departments address tend to be very disconnected from what truly matters from an ethical, moral, and philosophical point of view. For example, there is little appreciation of the value of bringing mathematical formalisms into discussions about the mind, or what that might look like in practice. Likewise there is close to no interest in preventing extreme suffering nor understanding its nature. Additionally, there is usually a disregard for extreme states of positive valence, and strange or exotic experiences in general. It may be the case that there are worthwhile things happening in departments and classes creating and studying this literature, but we find them characterized by processes which are unlikely to produce progress on their nominal purpose, creating a science of mind.

    • In particular, in academic philosophy of mind, we’ve seen very little regard for producing empirically testable predictions. There are millions of pages written about philosophy of mind, but the number of pages that provide precise, empirically testable predictions is quite thin.

  • What therapies does QRI recommend for depression, anxiety, and chronic pain?

    • At QRI, we do not make specific recommendations to individuals, but rather point to areas of research that we consider to be extremely important, tractable, and neglected, such as anti-tolerance drugs, neural annealing techniques, frequency specific microcurrent for kidney stone pain, and N,N-DMT and other tryptamines for cluster headaches and migraines.

  • Why does QRI think it’s so important to focus on ending extreme suffering? 

    • QRI thinks ending extreme suffering is important, tractable, and neglected. It’s important because of the logarithmic scales of pleasure and pain—the fact that extreme suffering is far worse by orders of magnitude than what people intuitively believe. It’s tractable because there are many types of extreme suffering that have existing solutions that are fairly trivial or at least have a viable path for being solved with moderately funded research programs. And it’s neglected mostly because people are unaware of the existence of these states, though not necessarily because of their rarity. For example, 10% of the population experiences kidney stones at some point in their life, but for reasons having to do with trauma, PTSD, and the state-dependence of memory, even people who have suffered from kidney stones do not typically end up dedicating their time or resources toward eradicating them.

    • It’s also likely that if we can meaningfully improve the absolute worst experiences, much of the knowledge we’ll gain in that process will translate into other contexts. In particular, we should expect to figure out how to make moderately depressed people happier, fix more mild forms of pain, improve the human hedonic baseline, and safely reach extremely great peak states. Mood research is not a zero-sum game. It’s a web of synergies.



Many thanks to Andrew Zuckerman, Mackenzie Dion, and Mike Johnson for their collaboration in putting this together. Featured image is QRI’s logo – animated by Hunter Meyer.

5-MeO-DMT vs. N,N-DMT: The 9 Lenses

TL;DR

Some substances seem to be much better at treating psychological trauma than others, even when they are seemingly similar in nature. We have reason to believe that 5-MeO-DMT is significantly better suited for this task than N,N-DMT (“DMT” from now on). In order to gain insight into why this difference exists, we investigate the phenomenological differences and similarities between the experiences produced by these two tryptamine psychedelics. In particular, we develop 9 lenses that show promise for understanding how 5-MeO-DMT and DMT differ:

  1. Space vs. Form: 5-MeO is more space-like than DMT.
  2. Crystals vs. Quasi-Crystals: 5-MeO generates more perfectly repeating rhythms and hallucinations than DMT.
  3. Non-Attachment vs. Attachment: 5-MeO seems to enable detachment from the craving of both existence and non-existence, whereas DMT enhances the craving.
  4. Underfitting vs. Overfitting: 5-MeO reduces one’s model complexity whereas DMT radically increases it.
  5. Fixed Points and Limit Cycles vs. Chaotic Attractors: 5-MeO’s effect on feedback leads to stable and predictable attractors while DMT’s attractors are inherently chaotic.
  6. Modulation of Lateral Inhibition: 5-MeO may reduce lateral inhibition while DMT may enhance it.
  7. Diffuse Attention vs. Focused Attention: 5-MeO diffuses attention uniformly over large regions of one’s experiential field, while DMT seems to focus it.
  8. Big Chunks and Tiny Chunks vs. A Power Law of Chunks: 5-MeO creates a few huge phases of experience (as in phases of matter) with a few remaining specks, while DMT produces a more organic power law distribution of chunk sizes.
  9. Integration vs. Fragmentation: 5-MeO seems to give rise to “neural integration” involving the entrainment of any two arbitrary subnetworks (even when they usually do not talk to each other), while DMT fragments communication between most networks but massively enhances it between some specific kinds of networks.

All of this together suggests that 5-MeO-DMT is better at helping you “reconnect with yourself” than DMT. And this may be key to treating trauma effectively.


What is Trauma?

I will start out by briefly mentioning an interesting property of psychological trauma. You see, trauma has a lot of somatic manifestations. Feeling disconnected from yourself,  like you are full of blockages, that you have numb regions in your body despite no physical damage, and so on, are all quintessential ways in which trauma shows up in a person’s everyday life. Given these manifestations, do these suggest any new way of treating this? How about using something that facilitates the communication between parts of your nervous system that are not on “speaking terms” with each other? Would giving our nervous system a kind of vibration that simultaneously entrains any two of its regions to make them act as a unit be of any help?


Psychotropic Treatment of Trauma

Based on tens of interviews, hundreds of trip reports, and a literature review, I have arrived at a tentative short list of drugs that have the highest potential to heal trauma (in decreasing order):

  1. 5-MeO-DMT
  2. MDMA
  3. Ketamine

They are all synergistic combined with music, vibration, strobes, and olfaction. And when wisely used, they all have the ability to help you move on past pain: stop ruminating, stop feeling like your behavior is inhibited, and stop having panic attacks associated with your past experiences.

At some point in the future I will provide direct empirical evidence for the claim that these three substances are uniquely good for treating trauma. Arguably psilocybin, ayahuasca, and LSD can be helpful in processing traumatic experiences too. But my claim is that the options I listed are uniquely good at deeply resolving the issues at an emotional level and bringing to you the opportunity to feel a profound and lasting sense of inner peace.

DMT won’t help as much as 5-MeO-DMT.

MDA is not as good as MDMA.

And DXM, ok, perhaps it can also be quite useful for trauma… but ketamine has something “extra” that really helps.

What is this?


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The Koan: 5-MeO-DMT, MDMA, Ketamine?

Perhaps we could gain a new perspective by framing this as a Koan: what do MDMA, 5-MeO-DMT, and ketamine have in common? You HAVE to the figure this out in the next 24 hours, or your guru will literally cut your cat in half. Motivated enough?

What do you do? Well, you start out by borrowing psychopharmacology books from the library. But does that help? When it comes to trauma, in traditional textbook neuroscience MDMA is at best just a footnote. Ketamine is not even mentioned for the most part, unless the book is hip, but even then it will be mentioned in the chapter about anaesthetics and painkillers; its psychoactive effects will be glossed over as “emergent phenomena”. No! What are you doing? Wasn’t John C. Lilly already talking about the far-out, extraordinarily bizarre, perhaps even literally inter-dimensional properties of “vitamin K” way back in the 70s? Then why is my 2007 “Drugs and the Brain” textbook so totally lacking in any kind of genuine phenomenological insight about this stuff?

And what about 5-MeO-DMT? You are lucky if the term appears even once in your $800 textbook. And if it does indeed appear, you can bet it will also be in a footnote, this time concerning matters such as “psychoactive animals”, “other tryptamines”, and “mesoamerican entheogens”. You will neither see 5-MeO-DMT mentioned in a personal identity philosophy textbook, nor in a neuroscience treatise on “neural synchrony”, nor in the part of academia focused on “innovation in the treatment of mental illness”.

It is sad to admit, but the official main-lined level of interest in the three most promising therapeutic tools for trauma listed above is a matter of sorting and assembling footnotes.

I am exaggerating a bit, of course.

MDMA’s therapeutic potential is gaining traction thanks to the tireless work of MAPS. S-Ketamine is now approved as an anti-depressant. And while 5-MeO-DMT is gaining popularity at a glacial pace, it is at this point by no means a secret. An increasing number of vocal members of the psychedelic community have been talking about 5-MeO-DMT for some years. People who have publicly emphasized how different five is from other psychedelics include Hamilton Morris, James Oroc, Martin Ball, Leo Gura, and Rak Razam. But what we still lack is rigorous scientific backing for these claims. After all, everyone is likely to want to sell their aesthetic preferences as universal truths about beauty and bliss, right? Thankfully, there are some early scientific indications already:

The above graph comes from a 2018 study that investigated the therapeutic effects of 5-MeO-DMT-containing toad venom relative to psilocybin. The dose used (the amount of buffo venom vaporized) had an estimated content of 5-7mg of 5-MeO-DMT, and the researchers classified 75% of the resulting experiences as meeting the criteria for a “complete mystical experience”. It measured people’s level of response with the Mystical Experiences Questionnaire (MEQ30), and as you can see from the graph above, in every category 5-MeO-DMT seems to be more powerful than psilocybin. The level of effectiveness was indeed found to be higher than all but the highest dose of psilocybin, and chances are that the study couldn’t show it was more effective than that because it was underpowered to detect it, and not because there is no difference (in other words, the sample size was not large enough for the difference between high-dose psilocybin and 5-MeO-DMT to reach statistical significance). Also bear in mind the key difference that the trip lasts under 20 minutes in total, meaning that even if the trip fails to produce full effects, you can still afford to try it again ten more times in the same time interval that it would have taken you to experience a full psilocybin trip. More so, it is important to point out that the dose of 5-MeO-DMT taken by the participants of this study is considered to be at the edge between “light” and “common” in PsychonautWiki’s entry on the drug*. Indeed, for many people the “breakthrough” tends to happen around 10mg, and I’ve heard of people using up to 30mg of it at a time. (Beware: if you ever try this – please don’t jump straight to a high dose, as this can cause serious trauma as a result.) Therefore, I think it is reasonable to expect that future studies will confirm what anecdotal data is currently screaming: that 5-MeO-DMT is more “powerful” and “mystical” in its effects than psilocybin, LSD, DMT, 2C-B, and all the rest.

But what this “power” and “mysticism” exactly amounts to still lacks clear and useful definitions. More so, is there any concrete reason why 5-MeO-DMT may be also superior at healing trauma relative to, eg. LSD or psilocybin? Technically, one could currently argue that since the presentation of “complete mystical states” is a mediating factor in whether psilocybin has long-lasting psychological benefits, that 5-MeO-DMT is more effective simply because it has a higher probability of causing this effect. But I would argue that the texture of 5-MeO-DMT peak experiences is different and not only just more intense, and that the way in which it is different matters for its therapeutic value.

To investigate this particular difference, we now move on to examining the phenomenological difference between 5-MeO-DMT and DMT.


5-MeO-DMT vs. N,N-DMT: The 9 Lenses

My experience is that a reasonable ~20% of people I talk to who have a long-standing interest in psychedelics have heard about 5-MeO-DMT’s special properties. However, only a much smaller percentage of people have actually tried it. At Qualia Computing we have talked about its exceptional phenomenological properties a number of times. Yet it remains that most readers who reach out have not themselves experienced it. Hence I have not really had access to quality trip reports in order to say anything meaningful about the way in which it is different from DMT.

Thankfully, I’ve recently interviewed someone who has a decent level of experience with 5-MeO-DMT (20+ trips), along with a significant level of experience with vaporized DMT (100+ trips), and is also acquainted with the combination (10+ trips with both substances at once).

Given the incredibly intense psychoactive effects of 5-MeO-DMT (both for good and bad), most people struggle to put into words anything meaningful about the state. That said, as it has been the case with a number of other states of consciousness (e.g. LSD, DMT, and MDMA) I feel compelled to try to offer a sane, rational, agnostic, and pragmatic description of its phenomenology. In particular, I think that 5-MeO-DMT’s unique trauma-healing potential really deserves a close look. I believe that it sheds light on a wide range of topics of interest such as neural annealing, the Symmetry Theory of Valence, and the pseudo-time arrow (video). With this in mind, I inquired with my interviewee about the differences between N,N-DMT and 5-MeO-DMT. Together, after a lengthy open-ended discussion, we found the following ways to compare them:

1. Space vs. Form

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One of the first things that stands out when you take DMT at even small doses is the way in which colors get intensified. This is a special case of a very generalizable effect: in fact, every perceptual feature you can point to is enhanced while on DMT, from the sharpness of edges and pointy things to the feeling of movement and rotation. The interviewee indeed said that a brain on DMT “becomes a powerful qualia machine“.

After trying 5-MeO-DMT for the first time, most people already familiar with DMT mention something along the lines of “I was surprised that I didn’t see many colors.” The visual component of five is rarely very colorful; if color appears, it is in the form of a golden or sometimes light faint magenta or green hue. For the most part, the visual component of the experience is black and/or white. At times, one can see rainbow halos, but like rare subatomic particles, on 5-MeO-DMT rainbow colors come in and out of the vacuum, as if somehow equivalent to it. The bulk of the visuals manifest in a dazzling sense of spaciousness, as if there was a cosmic paint called “transparent/translucent”. The space often feels immeasurable due to a lack of a reference frame from which to make a judgement in terms of known comparisons. But what inevitably stands out is that the space seems large, uniform, harmonious, smooth, and luminous. Somatic feelings blend with this space, and the uniformity and symmetry of it allows for energy to seamlessly move throughout it. It really is a remarkable effect, one which can easily give rise to the felt-sense of Open Individualism. Yet, despite the engrossingly engaging character of these feelings, there is very little narrative complexity in sight.

Who knew that empty space could be so much fun? That you could fit so much love and bliss in an (experiential) vacuum? More so, the more you are able to relax into it, the more you embrace the waves of equanimity, the more you allow the space to become perfectly smooth and seamless… the more blissful it all gets!**

2. Crystals and Quasi-Crystals

Here is an interesting thing – ultrasound has been used in order to bias the way in which water crystals form, and thus creating much more “cubical” water than is otherwise possible. More generally, the phenomenon of vibration affecting crystallization processes is worth considering as an explanatory framework. DMT comes with a particular vibe that some have identified as having a characteristic frequency somewhere between 20 and 30Hz, whereas 5-MeO-DMT’s vibe seems to be a notch higher, perhaps in the range of 30 to 40Hz. On these drugs, your attention is jittered back and forth at a certain frequency, and this affects your ability to focus on any given part of your experience. The specific jittering itself makes it harder and easier to construct and manipulate certain thought-forms over others.

Speculatively, this model says that the jittering of attention caused by 5-MeO-DMT and DMT give rise to crystal and quasi-crystal building blocks, respectively, for phenomenal objects in one’s experience.

Phenomenologically, it seems that the vibratory signature of DMT effects doesn’t wrap around your experience an integer number of times. Thus, what we will call, for lack of a better term, the qualia crystals that form while on DMT seem to be inherently unstable and alien to your normal way of cogitating. The fact that the vibrations don’t fit perfectly in one’s experiential field forces it to bend out of shape to accommodate such vibrations. The result is constant chaos – fluid instabilities as the core effect.

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Kelvin–Helmholtz instability (source)

On the other hand, with 5-MeO-DMT, it’s as if the vibration activates parts of the field of experience in exactly the right way for them to blend, unite, and resonate with one another. The vibrations fit perfectly inside one’s experiential field, and allows it to relax into its own natural shape. And this allows for perfect crystals of awareness to peacefully grow, multiply, and synchronize.

It is of course surprising that a tiny difference in the frequency of the vibe could have such large effects in the way phenomenology crystallizes. But this is true for other systems. When one talks about the complexity of shapes in resonant systems, for instance, Lissajou curves can provide a helpful intuition pump: in Lissajou curves, merely changing one of the frequencies by a small relative amount can result in a huge difference between the pictures drawn. From a simple circle to a complex mesh.

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According to the interviewee, 5-MeO-DMT would neatly correspond to one of the simplest Lissajou curves above, while the DMT sensations would be better evoked by one of the meshy ones.

With that said, it is worth mentioning that 5-MeO-DMT is probably not hitting the right frequencies merely by chance. It’s probably more that it is activating a system whose attractor is self-correcting and results in the kind of symmetrical crystallization that gives rise to deep feelings of bliss.

3. Attachment to Existence and Non-Existence

5-MeO seems to point at a super general sense of “relaxation”. A meditation teacher, Ajahn Brahm, talking about jhanas said that his mantra to achieve states of deep concentration and peace was: “Relax… to the maaaaaaaxxxx…”.

And according to the interviewee, the thrust of 5-MeO is that it feels like your nervous system is paradoxically injected with a lot of energy and yet the vibe of this energy is that of total and complete- ultimate?- relaxation. But our body and mind are not used to relaxing deeply. The contrast between this energy and one’s usual neurotic state can itself produce a lot of dissonance and resistance. In most cases, this is transient and contained to the first couple of minutes of the experience, though in higher doses and with bad luck, it can also spiral out of control. On small and moderate doses the energetic vibe of “relax to the max” takes over one’s experiential center of mass and teaches the rest of your nervous system how to relax.

It vibrates your nervous system in just the right way that all of your tensions, and hidden knots, and internalized stresses, bubble up to the surface, and you have the chance to try to “unravel” all of that tension.

After taking it a couple of times, you get the very nice feeling of being OK with whatever happens. 5-MeO-DMT might be described as a drug that allows you to reduce “thirst, craving, desire” in a very generalized kind of way. In Buddhist terms, this would be to reduce “Taṇhā“, which comes in three different kinds: “kāma-taṇhā (craving for sensual pleasures), bhava-taṇhā (craving for existence), and vibhava-taṇhā (craving for non-existence).” While we are used to hearing religious figures and moralists talk about the importance of not experiencing cravings for sensual pleasure, popular culture still lacks legible myths about the craving for existence and non-existence. So it comes as a shock for someone who has never developed meditative introspective insight just how much of our suffering has the flavor of either craving for existence or non-existence. Dosing on 5-MeO-DMT gives you a glimpse for what a mind devoid of these more subtle forms of craving feels like.

DMT comes with a vibratory frenzy that directly causes a lot of knots and tiny stress points throughout your entire experiential field. And to a large extent, how the experience unfolds is the result of you trying to manage all of those knots and stress points to avoid having them accumulate and concentrate in painful ways. The effect of this is that DMT acutely increases attachment to existence and non-existence. You wonder “what am I in this world?” and then cling to it, along with an intense fear of losing yourself in the world of vibration. The fear is quite involuntary and primal. And because you are clinging to who or what you are, there is something that you can lose, and that contributes to the feeling that the stakes are very high.acacia-trees-grown-on-the-african-savannah-stock-video-footage-png-tree-savannah-1920_1080

On 5-MeO you look at a landscape- say a tree in a Savannah- and you can see it in the most Zen way you can possibly imagine (and I don’t mean cutting cats in half). You think: “there is neither someone nor nobody in there” and “it’s all just arising and passing of ephemera”.

On DMT you look at the same landscape and you feel: “Oh gosh, what AM I in here? Am I that rock over there? That rock seems threatened by erosion! Am I the tree? But what if something comes and eats the tree?” and so on.

On DMT you feel like you are one of many little beings in a vast ecosystem. On 5-MeO-DMT you step back and you “realize” that you are the entire ecosystem.

In turn, this may explain to some extent the fact that the content of DMT hallucinations is often filled with exotic beings. And almost always, these beings have hyper-specific ways of life, tastes, intentions, and beliefs. The realms you experience on DMT are all saturated with attachment to existence and non-existence, and the beings you interact with are no exception. In fact, they may be a manifestation of those intensified cravings! From the interviewee:

“I’ve taken DMT about 100 times and have encountered many different vibes and kinds of intelligences in those realms. I’d love to map out the possible narratives – there are so many! Loosely speaking, I’ve had many different encounters with intelligent beings: from blissfully angelic and benevolent to outright demonic. Most of the beings I’ve encountered are somewhere in-between, and for the most part, tend to have pretty dualistic mindsets.

There is this whole class of beings I’d identify as harlequins/jesters that just love to play tricks with perception (I’m sure that’s what Terrence McKenna was pointing at).

Then there are “artists” which have a particular style that they explore and can range from emotionally self-sufficient to aggressively in-your-face about their work. The “look at THIS and look at THIS and look at THIS!!” kind of stance, where you are not given enough time to process what they’ve already shown you before they thrust even more stuff into you, and then attach ‘cookies’ into your etheric body to track you in future trips so you “like” and “subscribe” to their “interdimensional channel” or something like that.

There’s also a lot of beings that seem to want to tell you that they are confident that God does not exist and that “everything is allowed”. And I’ve felt that they are really indifferent to morality, but still have powerful abilities and unique qualia of a more scientific bent.

I once also encountered what felt like a true sadistic demon that played some really nasty tricks on my perception, and filled me with “etheric bugs” and had hundreds of little minions to attack me in many unpleasant ways. That said, I blame this on the fact that I was sleep deprived when I took DMT that one time, and it’s never happened before or since. But that experience gave me a lot of respect for the drug.

I’ve also encountered realms where they actually do consciousness research as such, and are benevolent and into engineering paradises. I even asked one of them if they knew my favorite philosopher, and they said “yes, what a nice fellow – we hope he will be more widely known in the future. We just wished that he wasn’t so sad a lot of the time.”

I have found that my pre-existing mood is the single most important variable that determines the kind of intelligences I encounter. So I’d really like to someday try MDMA and DMT combined. I suspect those would be very angelic beings most of the time.

Interestingly, I feel that while DMT feels profoundly spiritual, to a large extent it is less “nondual” than most other psychedelics. A lot of beings I’ve encountered simply don’t seem to care about oneness at all. But on LSD, mushrooms, and of course 5-MeO-DMT, the Golden Rule seems to play a very central role in the experience. Those experiences are much more of a “teaching” than the wacky stuff one encounters in the DMT realms.

When you take 5-MeO-DMT and DMT at the same time, you can really feel the contrast between the dualistic “us vs. them” vibe that underlies DMT and the unitive sense that underlies 5-MeO-DMT. I’ve experimented with the combo and found it to be super informative. And usually, I realize that while DMT turns your brain into a high-octane “qualia machine”, 5-MeO is in fact much more peaceful and happy in a deeper sense. I’d like to understand both, but my preferred “home” would be for sure the 5-MeO realms.”

4. Underfitting vs. Overfitting

One interesting lens with which to make sense of the difference between people who are open to experience and people who are not is that of model complexity, which casts this difference in terms of the statistical concepts of underfitting and overfitting.

Having narrow views, simple explanations, and enduring preferences is very good when the world itself is either very simple or impossible to understand. But having complex views, multi-layered explanations, and flexible preferences is more adaptive than the alternative in a world that is both complex and can be understood with some effort.

Indeed, some speculation about the nature of sleep from the predictive coding paradigm of cognition is that dreaming is a process of model complexity reduction. The information that we accumulate over the span of a day is incorporated in an ad-hoc fashion while awake, and only properly integrated (and pruned) after a good night’s sleep. This at least provides the theoretical precedent for describing a specific state of consciousness in terms of its effects on model complexity. And here we would propose that as a very general effect profile, 5-MeO-DMT reduces model complexity while N,N-DMT increases it.

As a consequence, we would posit that people who take five a lot will converge towards compelling yet over-simplified models of realty, whereas people who use DMT a lot will converge to overly complex and unnecessarily detailed explanation for even the simplest of phenomena.1__7OPgojau8hkiPUiHoGK_w

Perhaps in the future people could be diagnosed as chronic overfitters and underfitters. In turn, these two drugs could be given by prescription, for the maladies of improper model selection practices:

N,N-DMT would be given to the sufferers of too much worldview simplicity. People like this believe that the world is dominated by the struggle between capitalism and communism. They think that there is a 50% chance that God almighty exists. They assign zero probability to unlikely events, such as lizard people power conspiracies. In people like this, DMT is a powerful mind enhancer capable of challenging cartoonishly simple background assumptions and introducing a healthy dose of skepticism in mainstream narratives.

5-MeO-DMT would instead be given to people who are overwhelmingly embroiled in complex interpretations of the nature of reality. Whether it is in the realm of conspiracy theories, religious cults, the biochemistry of aging, or any such hopelessly convoluted field of research, a little five will unscramble the mind of the compulsive overfitter. Thanks to the drug, the Bayesian puncture, the Occam’s cut, and the pragmatic so what coalesce into a decimating hit to the load-bearing hub-nodes that feed unfalsifiable belief systems. The model complexity reduction effect dissolves entire subfields, assimilates clusters, and seamlessly mends discontinuities in the reality mappings of the patient. At moderate dosages and treatment regimes, the sufferer recovers fully. The sufferer often ends up healed of their traumas, and occasionally healed of many more things than expected. At levels much above those of the therapeutic standard of care, there is a risk that the treatment may result in the healing of the fundamental traumas of conscious experience. The drug may offer the patient a chance to relinquish phenomenal reality in exchange for an extemporal “ultimate relief”. To extinguish the flame of existence, as they say.41592_2016_Article_BFnmeth3968_Fig1_HTML

Importantly, after 5-MeO-DMT therapy, the patient is, let’s say (for the sake of speculating), 20 times as likely as members of the general public to say yes to questions like “Are we all one consciousness?”, “Is the world a process created for the refinement of our souls?” and “Is the universe made of infinite consciousness?”.

So where does that leave us? The good news is that this may have game-theoretical benefits for the side of consciousness in the eternal battle between consciousness and pure replicators. The bad news is that it can overwrite important information obtained from the senses, one’s education, and logical reasoning:

Becoming the God of “I-AM-Now-ness” and filling your entire experiential field with that flavor of awakening is a recipe for ecstasy, not for good epistemology.

Indeed, the patient may become a bit hooked to the simplification of their model complexity; to make reality as they know be replaced by a simpler, yet more intense, version of perceived reality is very tempting. It can be seductive to embrace a view like “you are God and you have created everything for your own amusement” or “you are the dream of God”. Rather than compassion, why not indifference? Being the “way God entertains itself” is both poetically satisfying and super trippy. A lot of people would find that such belief adds some spice to their lives. Overfitting-and-underfitting-effect-on-error

But the price of truth is everything. In turn, it would be ideal to complement any model complexity reduction that goes too far with a healthy amount of prediction errors.

5. Fixed-Points and Limit Cycles vs. Chaotic Attractors

The brain contains many self-correcting feedback systems. Psychedelics in general can be modeled as drugs that mess with the inhibitory component of excitation-inhibition feedback systems. They accomplish this, quite possibly, by disrupting the inhibitory serotonergic connections coming from the cortex that gate the excitatory input coming from the thalamus. This may account for why tracers look the way they do – the failure to inhibit the thalamus results in looped replays of recent states. This may go a long way in explaining why people find “video feedback” so trippy and fascinating. Namely, because a lot of psychedelic effects can be understood as feedback getting out of control, literally.

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More concretely, at the Harvard talk on the Hyperbolic Geometry of DMT experiences I introduced this notion that each DMT experience as a whole can be thought of as a trajectory in the energy vs. complexity landscape. Here, the vertical axis indicates the degree of energy of the experience (roughly corresponding to the intensity, brightness, and amount of qualia), while the horizontal axis represents how much information is encoded in the experience. One interesting operationalization of information is through the concept of symmetry breaking***, in which case the horizontal axis approximately tracks the “distance from perfectly symmetrical spaces in terms of number of symmetry breaking operations”.

I then postulated that we could generate an ontology based on feedback + noise to explain how two DMT trips of roughly the same level of intensity can nonetheless contain very different amounts of information.

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What I did not mention at the time was that while DMT does have the ability to send you to any place in the energy-complexity landscape, most of the experiences are in the region of middle-complexity. In fact, especially strong DMT trips tend to become fully chaotic, so there is even a mild correlation between dosage and complexity. On the other hand, 5-MeO-DMT tends to propel you towards the low-complexity region of the space.

Using a feedback system ontology we could thus posit that 5-MeO-DMT modifies the feedback parameters of your brain in such a way that the states it gives rise to are ether fixed points or short limit cycles:

The video above depicts a fixed point (as with the other animations below, I took this from an old 1984 video about video feedback you can see here). A fixed point is a configuration of the system that is stable upon feedback iterations. In the video above we see a fixed point consisting of a cross (presumably the result of the camera having a 90 degree tilt) that is then perturbed and eventually collapses into just a single circular dot at the center.

The above are limit cycles. The first (left) is a comparatively simple limit cycle in that every stage along its reproduction cycle is very similar to each other. The second (right) one is a bit more complex, yet despite a long winded path, it really does repeat more or less perfectly over and over. 5-MeO-DMT limit cycles are more akin to the one on the left, but on occasion may be a bit more complex and rhythmic over the span of seconds. Either way, there is often a strong pull towards a simple resonant pattern with remarkable stability.

Contrast that with chaotic attractors:

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Chaotic pseudo-time arrow

When we have actual chaos, the states continue to change indefinitely. We could then posit that DMT’s characteristic jittering seems to prevent the formation of stable fixed points or short limit cycles. Despite both DMT and 5-MeO-DMT disrupting feedback in the brain, the subtle differences in the way parameters of this feedback are modified can make all the difference between perfectly simple and smooth results and the endless generation of chaotic structures.

6. Modulating Lateral Inhibition

Another exciting lens with which to look at the difference between these psychedelics is by allusion to lateral inhibition: according to a couple of recent trip reports I received from another anonymous source, there is a remarkable difference between the tracers of 5-MeO-DMT and those of DMT. In particular, the anonymous tripper points out that DMT tracers are chains of concatenated positive and negative after-images of the stimulation source, whereas 5-MeO-DMT only produces positive after-images.

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Stare at the cross. The green ball you see as a result is the “negative after-image” of the missing purple dot. 

In other words, when you see a blue ball moving on a screen, on DMT you will see tracers of that ball that change in color from blue to yellow to blue again and so on, all following after the original blue ball. But on 5-MeO-DMT, one will only see a long blue tracer. This is a remarkable difference, and if true, it would seem to be an important hint.****

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Orientation selectivity map in the visual cortex

Lateral inhibition in the cortex prevents the overlapping of incompatible features in one’s own experience. For example, the primary visual cortex shows a map of orientation selectivity as shown above. Each hypercolumn is selective to only a specific orientation, and the surrounding hypercolumns are selective to different orientations. More so, via lateral inhibition, when a hypercolumn is activated, it inhibits the surrounding ones.

In this model, DMT would perhaps leave this process untouched, so that when the brain is massively energized, it still maintains this flip-flopping between each feature and its complement. Indeed, some people have described DMT as turning half of your neurons fully on, the other half of your neurons fully off, then inverting the activation so that the off neurons are turned on and the on ones are turned off, and flip-flopping between these two steps many times per second. Could this be the phenomenal expression of having energized checkerboard patterns of excitation and inhibition saturating your cortex? That is, taking a system with in-built lateral inhibition into over-drive?

5-MeO-DMT, on the contrary, seems to allow for “all colors to blend together into pure white light”, and “the past and the future to collapse into the present”, and the “self-other distinction to be dissolved”, and so on. Intuitively, if the drug is biochemically disabling lateral inhibition, that could be reflected as a profound sense of unity and interconnectedness at the phenomenological level, “transcending every last barrier”.

7. Diffuse Attention vs. Focused Attention

As we mentioned earlier, DMT tends to come with a feeling of “becoming tense” while 5-MeO-DMT has a primary vibe of “becoming relaxed”. One way in which we can model this is in the way the drugs influence whether your attention is focused or diffuse. Now, I should say that this model will be necessarily incomplete because at the peak of a 5-MeO experience one often does in fact feel super focused in some way. But I would posit that this sense of focus is much more holistic than the way our common-sense use of the term would suggest. The focus on DMT, on the other hand, does feel very much akin to the “conventional” sense of focus, where you are able to precisely position figure and ground in such a way that they have as much contrast as possible.dmt_from_scalable_locally_injective_maps

In a way, the beings one encounters on DMT could be thought of as “attentional attractors”. As you create a lot of little focal points during the experience, these begin to build up and define the contents of your mind. Each focal point makes it easier for you to create another one nearby. This snowballs into an effect where there are clusters of focal points that become the “centers of mass” of the narrative. These could very well be what underlies the “beings” on DMT. Using Buddhist terms again, DMT beings might perhaps be thought of as exotic “nimittas“: attention hubs.

Also, because the experience is high-dimensional and changes your sense of what “understanding” even means, it seems that the feeling of super-intelligence on DMT might be a projection of one’s own super-intelligence (of a certain kind) in the state.

In contrast, 5-MeO-DMT makes it easy to de-focus on anything. To let go, and experience it in a diffuse way.

8. Big Chunks and Tiny Chunks vs. A Power Law of Chunks

Geology uses the word matrix in way that is very different from either math or science fiction aficionados. In geology, a matrix is the entire mass of materials on a rock within which crystals, grains, and clasts are found. As Anders and Maggie discussed recently, the way in which minerals form depends to a large extent on the presence of water in the process of crystallization. The huge diversity of minerals we see on Earth’s surface is partly a result of the availability of water in the mantle. Perhaps a lens with which to see DMT is as playing the same role in the brain as water does in fractional crystallization. It lubricates the matrix of your mind, which enables the crystallization of countless qualia exotica. 5-MeO-DMT instead homogenizes the kinds of crystals that can form.

In brief, DMT is to 5-MeO-DMT as a matrix of diverse minerals is to a mono-phasic large enclave. DMT is like complex music (cf. music as an ordered phase of sound) while 5-MeO-DMT is like a single mantra repeated over and over. Is this metaphor useful? It seemed to resonate with the interviewee.

9. Integration vs. Fragmentation

In Neural Annealing, Mike Johnson argues that what makes MDMA special for healing trauma is what at QRI we call integration:

On MDMA’s strangely powerful therapeutic effects, I’d suggest MDMA shares the ‘basic psychedelic package’ with substances like LSD and psilocybin (albeit a little weaker at common doses). Anything with this ‘baseline’ package significantly increases the energy parameter of the brain, which both allows escape from bad local minima and canalizes the brain’s core CSHWs, which both should be highly therapeutic. My intuition is MDMA may also have a particular effect on stochastic firing frequencies of neurons, and that this effect essentially acts as an emergent metronome – and this metronome will drive synchronicity between diverse brain regions. Given the presence of such a region-spanning ‘clean’ metronomic signal, brain regions that have partially ‘stopped talking to each other’ will re-establish integration, and some of this integration will persist while sober (or rather, some of the reasons for the lack of integration will have been negotiated away during the MDMA-driven integration). Plausibly this ‘emergent metronome’ effect may also underlie the particular phenomenological effects of 5-MeO-DMT as well, particularly in terms of sense of unity, high valence, and therapeutic potential. (HT to Steve Lehar for pointing at this ’nystagmus’ phenomenon as being somehow linked to MDMA’s mood-lifting effect, and to Andrés for calling my attention to Lehar’s work and suggesting 5-MeO-DMT may also share this mechanism.)

Like most other psychedelics, N,N-DMT also shares the same ‘basic psychedelic package’ and can have beneficial therapeutic effects. But it lacks this ‘special’ ability that allows arbitrary parts of your nervous system to rhythmically entrain with one another. This “emergent metronome” on MDMA and 5-MeO-DMT works as a kind of universal “vibratory currency” and results in a reduction of inner dissonance to a much greater extent than (relatively) simple “energizers” like DMT.

To Wrap Up

We hope that the above discussion has given you an idea about the difference between DMT and 5-MeO-DMT and why this matters for their therapeutic potential. The above is just the start of a deep inquiry into the topic that will certainly take many years, but we believe that it is a novel way of seeing the contrast between these two substances that may be generative for others. We also believe that it is very worth trying: nailing down this difference may be incredibly important to develop novel ways of treating mental illness. While DMT will undoubtedly continue to dazzle and amaze people curious about the state-space of consciousness, the superlative potential of 5-MeO-DMT to heal trauma puts it on a different level of importance altogether.

In the future we shall also explain why MDMA and ketamine have this potential. And ultimately, as we begin to understand what makes these substances so special, we hope to find ways of creating effective therapies from first principles. Stay tuned.



* The toad venom dose was 50mg, with an estimated 5-7mg of 5-MeO-DMT. This is admittedly likely to produce somewhat more potent effects than just 5 to 7mg of pure 5-MeO-DMT. But the extent of this enhancement is currently poorly understood, and you can find many people online saying that the difference is tiny and others who argue it is enormous. Given just how intense and qualitatively unique pure 5-MeO-DMT already is, I think that applying Occam’s razor would tell us that “it’s just the 5-MeO-DMT itself”. So while I am ready to accept the possibility of profound synergy between other tryptamines in toad venom and 5-MeO, I am not holding my breath for it. I, rather, expect that the difference between 5-MeO alone and the full-spectrum stuff will be akin to the difference between drinking 10 shots of vodka and drinking 10 shots of vodka and one chamomile tea. Namely, a real but largely inconsequential difference.

** This, of course, blends well with the Symmetry Theory of Valence, a subject to which we shall return in the near future.

*** This is where information-less states are those which are perfectly symmetrical, and the information content of a state is defined as the minimum number of symmetry breaking operations needed to transform an information-less state into it.

**** This is admittedly very weak evidence so far. If you have experience with both of these compounds and have explored the way in which they give rise to after-images, please let me know if you can confirm or deny the effect here mentioned.


Picture: Andrés & Claudia Silva Ruiz

Mini-Series on Open Individualism

Part 1: Introduction

In this video I introduce the concept of Open Individualism- the idea that we are all one consciousness -, why it is relevant, and who has historically been a proponent of it (Hinduism, Einstein, Schopenhauer, Schrödinger, etc.).

We also cover the fact that there is a distinction between Open Individualism as an experience and Open Individualism as a philosophical position with rigorous arguments. I mention that I generally consider arguments to be more powerful and useful than just relying on first-person experiences, though experiences certainly have their place.

Part 2: Definitions

We define and illustrate:

  • Closed Individualism (“you are a separate observer that exists from moment to moment”)
  • Empty Individualism (“you are just a moment of experience”)
  • Open Individualism (“we are all one consciousness”)

Part 3: Strongest Arguments

In this video we provide some of the strongest arguments in favor of Open Individualism:

  • Based on continuity of identity from moment to moment.
  • Reductio ad absurdum of Closed Individualism.
    • Fission.
    • Fussion.
    • Lack of viable Identity Carriers (IC).
  • Based on parsimony.
  • Undecidability.
  • Self-locating uncertainty when taking a “view from nowhere”.

Part 4: Loneliness, Psychosis, Ecstasy

I address some key considerations when investigating Open Individualism:

  1. It is crucial to distinguish between our human feelings about a certain idea and the merits and drawbacks of that idea on its own.
  2. Open Individualism tends to cause a lot of bliss at first (caused by defanging death)
  3. But Open Individualism can often take a turn for the bad.
  4. It makes you realize that you won’t only not die, which is good, but also be forced to experience all of the suffering of the world (or multiverse).
  5. More so, it can make you feel “cosmically lonely” – a feeling typical of bad trips where the focus is the pursuit of oneness.
  6. While the increased sense of responsibility caused by Open Individualism is good, it is important not to be overwhelmed by the suffering of the world. As they say “one day at a time” and perhaps we could extend that advise to “one lifetime at a time”.
  7. The feeling of loneliness is likely the result of mixing deep brain circuits evolved to track things like one’s place in the tribe via feelings of belongingness and togetherness, which can get deactivated or over-activated when fully internalizing otherwise-neutral philosophical viewpoints. In other words, those feelings are reflections of our mammal brain’s response to Open Individualism rather than inherent to the philosophy in and of itself.

I also briefly mention the interesting relationship between the ways we represent the world and valence (i.e. the pleasure-pain axis). Given the Symmetry Theory of Valence, which claims that more “consonant and symmetrical” states of consciousness feel better, experiencing “unitive states of mind” usually comes with the “dissolution of internal boundaries”. Therefore, to actively simulate a world where we are all one is likely to come with very positive feelings (perhaps even orgasmic, and ecstatic). Yet, this is not intrinsic of oneness as such – rather, it’s an artifact of the way valence is implemented in the brain! Subtle, but key, distinction.

Finally, I also explain that “the highest truth” is not oneness:

In some sense, Open Individualism is “level 0” – it is the start of a journey of self-discovery. We still need to address things like how to eliminate extreme suffering, understand how physics describes fields of qualia, the binding problem, how causality interfaces with consciousness, what makes consciousness have an “arrow of time”, and so on. While oneness is a piece of the puzzle, it is by no means “the final answer”. To think otherwise leads to mental pathologies that constrict- rather than expand- one’s understanding and engagement with the world.

Part 5: Ethics, Coordination, Game Theory

In this video I discuss the beneficial implications of Open Individualism. Namely:

  1. Its ethical implications, where one feels a sense of responsibility for the wellbeing of all sentient beings.
  2. Its ability to solve coordination problems.
  3. Its game-theoretical effects.

I cover how a cultural, philosophical, and scientific movement that grounds the feelings of oneness and universal love in rigorous philosophy and science would be much more powerful and consequential than yet another attempt at a naïve spreading of “peace, love, and harmony”. Indeed, it is the philosophical strength of Open Individualism, rather than just its experiential component, that makes it viable as a tool for solving coordination problems.

In particular, I explain that studying 5-MeO-DMT and MDMA from a rigorous, scientific, and methodical point of view is one of the most promising ways of changing the world for the better. Creating reliable, sane, and integrative methods of experiencing oneness and universal love could help us transform weak feelings of altruism into a solid and powerful new conception of decision theoretic rationality.

We invite you to think with us about how to carry this out for the benefit of all sentient beings.

5-MeO-DMT Awakenings: From Naïve Realism to Symmetrical Enlightenment

In the following video Leo Gura from actualized.org talks about his 30-day 5-MeO-DMT streak experiment. In this post I’ll highlight some of the notable things he said and comment along the way using a QRI-lens to interpret his experiences (if you would rather make up your mind about what he says without my commentary just go and watch the video on your own before reading what I have to say about it).

TL;DR: Many of the core QRI paradigms such as Neural Annealing, the Symmetry Theory of Valence, the Tyranny of the Intentional Object, and Hyperbolic Geometry on Psychedelics have a surprising degree of explanatory power when it comes to making sense of the peculiar process that ensues when someone takes a lot of 5-MeO-DMT. The deep connections between symmetry, valence, smooth geometry, and information content are made clear in this context due to the extreme and purified nature of the states induced by the drug.


Introduction

Recently Adeptus Psychonautica (who has interviewed me in the past about the hyperbolic geometry of DMT experiences) put out a video titled “When you have taken too much – Actualized.org“. This video caught my attention because Leo Gura did something that is rather taboo in spiritual communities, and for good reasons. Namely, he tried to convince the viewers that he had achieved a level of awakening that nobody (or perhaps only a few people) on the entire planet had ever reached. He then said he was going to isolate for a month to integrate these profound awakenings and come back with a description of what they are all about.

Thankfully I didn’t have to wait a month to satisfy my curiosity and see what happened after his period of isolation because by the time I found about it he had already posted his post-retreat video. Well, it turns out that he used those 30 days of isolation to conduct a very hard-core psychedelic experiment. Namely, he took high doses of 5-MeO-DMT daily for the entire month. I’ve never heard of anyone doing this before.

Learning about what he experienced during that month is of special interest to me for many reasons. In particular, thanks to previous research about extreme bliss and suffering, we had determined that 5-MeO-DMT is currently the psychedelic drug that has the most powerful and intense effects on valence. Recall Logarithmic Scales of Pleasure and Pain (video): many lines of evidence point to the fact that extreme states of consciousness are surprisingly powerful in ways that are completely counterintuitive. So when Leo says that there are “many levels of awakening” and goes on to discuss how each level is unrecognizably more intense and deeper than the previous one, I am very much inclined to believe he is trying to convey a true property of his experiences. Note that Leo did not only indulge in psychedelics; we are talking about 5-MeO-DMT in particular, which is the thermonuclear bomb version of a psychoactive drug (as with Plutonium, this stuff is best handled with caution). More so, thankfully Leo is very eloquent, which is rare among people who have had many extreme experiences. So I was very eager to hear what he had to say.

While I can very easily believe his trip reports when it comes to their profundity, intensity, and extraordinary degree of consciousness, I do not particularly find his interpretations of these experiences convincing. As I go about describing his video, I will point out ways in which you can take as veridical his phenomenological descriptions without at the same time having to agree with his interpretations of them. More so, if you end up exploring these varieties of altered states yourself, by reading this you will now at least have two different and competing frameworks to explain your experiences. This, I think, is an improvement. Right now the psychedelic and scientific community has very few lenses with which to interpret something as extraordinary as 5-MeO-DMT experiences. And I believe this comes at a great cost to people’s sanity and epistemic rationality.

What Are Leo’s Background Assumptions?

In the pre-retreat video Leo says that his core teachings (and what he attempts to realize on his own self) are: (1) you are literally God, (2) there is nothing but consciousness – God is infinite consciousness, (3) everything is states of consciousness – everything at all times is a different state of consciousness, (4) you are love – and love is absolute – this is all constructed out of love – fear is just fear of aspects of yourself you have disconnected from, (5) you have no beginning and no end, (6) you should be radically open-minded. Then he also adds that physical and mental health issues are just manifestations of your resistance to realizing that you are God.

What Are My Background Assumptions?

Personal Identity

I am quite sympathetic to the idea of oneness, which is also talked about with terms like nonduality and monopsychism. In philosophical terminology, which I find to be more precise and rigorous, this concept goes by the name of Open Individualism – the belief that we are all one single consciousness. I have written extensively about Open Individualism in the past (e.g. 1, 2, 3), but I would like to point out that the arguments I’ve presented in favor of this view are not based on direct experience, but rather, on logical consistency from background assumptions we take for granted. For instance, if you assume that you are the same subject of experience you were a second ago, it follows that you can exist in two points in space-time and still be the same being. Your physical configuration is different than a few seconds ago (let alone a decade), you have slightly different memories, the neurons active are different, etc. For every property you point out as your “identity carrier” I can find a counter-example where such carrier changes a little while you still remain the same subject of experience. Add to that teleportation, fission, fusion, and gradual replacement thought experiments and you can build a framework where you can become any other arbitrary person without a loss of identity. These lines of argumentation coupled with the transitivity of identity can build the case that we are indeed all one to begin with.

But realize that rather than saying that you can grasp this (potential) truth directly from first person experience, I build from agreed upon assumptions to arrive at an otherwise outlandish view. Understanding the argument does not entail “feeling we are all one”, and neither does feeling we are all one entails understanding the arguments!

Indirect Realism About Perception

There is a mind-independent world out there and you never get to experience it directly. In some sense, we each live in a private skull-bound world-simulation that tracks the fitness-relevant features of our environment. Hence, during meditation, dreaming, or psychedelic states you are not accessing any sort of external reality directly, but rather, exploring possible configurations and qualities of your inner world-simulation. This is something that Leo may implicitly not realize. In particular, interpreting 5-MeO-DMT experiences through direct realism (also called naïve realism – the view that you experience the world directly through your senses) would make you think that you are literally merging with the entire cosmos on the drug. Whereas interpreting those experiences with indirect realism merely entails that your inner boundaries are dissolving. In other words, the partitions inside your world-simulation are what implements the feeling of the self-other duality. And since 5-MeO-DMT dissolves inner boundaries, it feels as though you are becoming one with your surroundings (and the rest of reality).

Physicalism and Panpsychism

An important background assumption is that the laws of physics accurately describe the behavior of the universe. This is distinct from materialism, which would also posit that all matter is inherently insentient. Physicalism merely says that the laws of physics describe the behavior of the physical, but leaves its intrinsic nature as an open question. Together with panpsychism, however, physicalism entails that what the laws of physics are describing is the behavior of consciousness.

Tyranny of the Intentional Object

We tend to believe that what makes us happy is external to us, while in reality happiness is a state of consciousness triggered by external circumstances. Our minds lead us to believe otherwise for evolutionary reasons.

Valence Structuralism

What makes an experience feel good or bad is not its semantic content, its computational use, or even whether the experience is self-reinforcing or not. What makes experiences feel good or bad is their structure. In particular, a very promising idea that will come up below is that highly symmetrical states of consciousness are inherently blissful, such as those we can access during orgasm, meditation, psychedelics, or even just good food and a hug. Recall that 5-MeO-DMT dissolves internal boundaries, and this is indicative of increased inner symmetry (where the boundaries themselves entail symmetry breaking operations). Thus, an exotic state of oneness is blissful not because you are merging with God, but “merely” because it has a higher degree of symmetry and therefore it’s valence is higher than what we can normally experience. In particular, the symmetry I’m talking abut here may be an objective feature of experiences perhaps even measurable with today’s neuroimaging technology.

There are additional key background philosophical assumptions, but the above are enough to get us started analyzing Leo’s 5-MeO-DMT journey from a different angle.


The Video

[Video descriptions are in italics whereas my commentary is bolded.]

For the first 8 minutes or so Leo explains that people do not really know that there are many levels of enlightenment. He starts out strong by claiming that he has reached levels of enlightenment that nobody (or perhaps just a few people) have ever reached. More so, while he agrees with the teachings of meditation masters of the past, he questions the levels of awakening that they had actually reached. It takes one to know one, and he claims that he’s seen things far beyond what previous teachers have talked about. More so, he argues that people simply have no way of knowing how enlightened their teachers are. People just trust books, gurus, teachers, religious leaders, etc. about whether they are “fully” enlightened, but how could they know for sure without reaching their level, and then surpassing them? He wraps up this part of the video by saying that the only viable path is to go all the way by yourself – to dismiss all the teachers, all the books, and all the instructions and see how far you can go on your own when genuinely pursuing truth by yourself.

With this epistemological caveat out of the way, Leo goes on to describe his methodology. Namely, he embarked on a quest of taking 5-MeO-DMT at increasing doses every day for 30 days in a row.leo_10_05

At 10:05 he says that within a week of this protocol he started reaching levels of awakening so elevated that he realized he had already surpassed every single spiritual teacher that he had ever heard of. He started writing a manifesto explaining this, claiming that even the most enlightened humans are not truly as awake as he became during that week. That it had became “completely transparent that most people who say they are awake or teach awakening are not even 1% awake”. But he decided not to go forward with the manifesto because he still values the teachings of spiritual leaders, whom according to him are doing a great service to mankind. He didn’t want to start, what he called, a “nonduality war” (which is of course a fascinating term if you think about it).

The main thing I’d like to comment here is that Leo is never entirely clear about what makes an “awakening experience” authentic. From what I gather (and from what comes next in the video) we can infer that the leading criteria consists of a fuzzy blend of experience of certainty, feeling of unity, and sense of direct knowing coupled together. To the extent that 5-MeO-DMT does all of these things to an extraordinary degree, we can take Leo on his words that he indeed experienced states of consciousness that feel like awakening that are most likely inaccessible to everyone who hasn’t gone through a protocol like his. What is still unclear is how exactly the semantic contents of these experiences are verified by means other than intuition. We will come back to that.

At 16:00 he makes the distinction between awakening as merely “cessation”, “nothingness”, “emptiness”, “the Self”, or that “you are nothing and everything” versus what he has been experiencing. He agrees that those are true and worthy realizations, but he claims that before his experiences, these understandings were still only realized at a very “low level”. Other masters, he claims, may care about ending suffering, about peace, about emptiness, and so on. But that nobody seems to truly care about understanding reality (because otherwise they would be doing what he’s doing). He rebukes possible critics (arguably of the Zen variety) who would say that “understanding is a function of the mind” so the goal shouldn’t be to understand. He asserts that no, based on his lived experience, that consciousness is capable of “infinite understanding”.

Notwithstanding the challenges posed by ultrafinitism, I am also inclined to believe Leo that he has experienced completely new varieties of “understanding”. In my model of the mind, understanding something means to have the ability to render it in your world-simulation in a particular kind of way that allows you to see it from every possible angle you have access to. On 5-MeO-DMT, as we will see to a greater extent below, a certain new set of projective operations get unlocked that allow you to render information from many, many more points of view at the same time. It is unclear whether this is possible with meditation alone (in personal communication, Daniel Ingram said yes) but it is certainly extraordinarily rare for even advanced meditators to be able to do this. So I am with Leo when it comes to describing “new kinds of understandings”. But perhaps I am not on board when it comes to claiming that the content of such understandings is an accurate rendering of the structure of reality.

At 18:30 Leo asserts that what happened to him is that over the course of the first week of his experiment he “completely understood reality, completely understood what God is”. God has no beginning and no end. He explains that normal human understanding sees situations from a single point of view (such as from the past to the future). But that actual infinite reality is from all sides at once: “When you are in full God consciousness, you look around the room, and you can see it from every single point of view, from an infinite number of angle and perspectives. You see that every part of the room generates and manufactures and creates every other part. […] Here when you are in God consciousness, you see it from every single possible dimension and angle. It’s not happening lilnearly, it’s all in the present now. And you can see it from every angle almost as though, if you take a watermelon and you do a cross-section with a giant knife, through that watermelon, and you keep doing cross-section, cross-section, cross-section in various different angles, eventually you’ll slice it up into an infinite number of perspectives. And then you’ll understand the entire watermelon as a sort of a whole. Whereas usually as humans what we do is we slice down that watermelon just right down the middle. And we just see that one cross-section.”

Now, this is extremely interesting. But first, it’s important to point out that here Leo might implicitly be reasoning about his experience through the lens of direct realism about perception. That is, that as he experiences this profound sense of understanding that encompasses every possible angle at once, he seems to believe that this is an understanding of his environment, of his future and past, and of reality as a whole. On the other hand, if you start out assuming indirect realism about perception, how you interpret this experience would be in terms of the instantiation of new exotic geometries of your own world-simulation. Here I must bring up the analysis of “regular” DMT (i.e. n,n-DMT) experiences through the lens of hyperbolic geometry. Indeed, regular DMT elevates the energy of your consciousness, which manifests in brighter colors, fast movement, intricate and detailed patterns, and as curved phenomenal space. We know this because of numerous trip reports from people well educated in advanced mathematics who claim that the visual symmetries one can experience on DMT (at doses above 10mg) have hyperbolic curvature (cf. hyperbolic orbifolds). It is also consistent with many other phenomena one can experience on DMT (see the Eli 5 for a quick summary). But you should keep in mind that this analysis never claims that you are experiencing directly a mind-independent “hyperspace”. Rather, the analysis focuses on how DMT modifies the geometric properties of your inner world-simulation.

Hyperbolic Geometry of DMT Experiences copy 47

Energy-complexity landscape on DMT

Hyperbolic Geometry of DMT Experiences copy 38

DMT trip progression

Intriguingly, our inner world-simulations work with projective geometry. In normal circumstances our world-simulations have a consistent set of projective points at infinity – they render the modal and amodal features of our experience in projective scenes that are globally consistent. But psychedelics can give rise to this phenomenon of “point-of-view-fragmentation“, where your experience becomes a patchwork of inconsistent projective renderings. So even on “regular” DMT you can get the profound feeling of “seeing something from multiple points of view at once”. Enhanced with hyperbolic geometry, this can cause the stark impression that you can explore “hyperspace” with a kind of “ultra-understanding”.

Looking beyond “regular” DMT, 5-MeO-DMT is yet more crazy than that. You see, even on DMT you get the feeling that you are restricted in the number of points of view from which you can see something at the same time. You can see it from many more points of view than normal, but it’s still restricted. But the extreme “smoothing” of experience that 5-MeO-DMT causes makes it so that you cannot distinguish one point of view from another. So they all blend together. Not only do you experience semantic content from “multiple points of view at once” as in DMT, but you can erase distinctions between points of view so that one’s sense of knowing arises involving a totally new kind of projective effect, in which you actually feel you can see something from “every point of view at once”. It feels that you have unlocked a kind of omniscience. This already happens on other psychedelics to a lesser extent (and in meditation, and even sober life to an even lesser extent, but still there), and it is a consequence of smoothing the geometry of your experience to such an extent that there are no symmetry-breaking imperfections “with which to orient a projective point”. I suspect that the higher “formless” jhanas of “boundless space” and “boundless consciousness” are hitting at this effect. And on 5-MeO-DMT this effect is pronounced. More so, because of the connection between symmetry and smoothness of space (cf. Geometry Through the Eyes of Felix Klein) when this happens you will also automatically be instantiating a high-dimensional group. And according to the Symmetry Theory of Valence, this ought to be extraordinarily blissful. And indeed it is.

This is, perhaps, partly what is going on in the experience that Leo is describing. Again, I am inclined to believe his description, but happy to dismiss his naïve interpretation.

indras_net

Indra’s Net

At 23:15 Leo describes how from his 5-MeO-DMT point of view he realized what “consciousness truly is”. And that is an “infinitely interconnected self-communicating field”. In normal everyday states of consciousness the different parts of your experience are “connected” but not “communicating.” But on 5-MeO, “as you become more conscious, what happens is that every point in space inter-connects with itself and starts to communicate with itself. This is a really profound, shocking, mystical experience. And it keeps getting cranked up more and more and more. You can call it omniscience, or telepathy. And it’s like the universal communication system gets turned on for the first time. Right now your conscious field is not in infinite communication with itself. It’s fragmented and divided. Such that you think I’m over here, you are over there, my computer is over here, your computer is over there…”. He explains that if we were to realize we are all one, we would then instantly be able to communicate between each other.

Here again we get extremely different interpretations of the phenomena Leo describes depending on whether you believe in direct or indirect realism about perception. As Leo implicitly assumes direct realism about perception, he interprets this effect as literally switching on an “universal communication system” between every points in reality, whereas the indirect realist interpretation would be that you have somehow interlocked the pieces of your conscious experience in such a way that they now act as an interconnected whole. This is something that indeed has been reported before, and at QRI we call this effect “network integration“. A simple way of encapsulating this phenomenon would be by saying that the cross-frequency coupling of your nervous system is massively increased so that there is seamless information and energy transfer between vibrations at different scales (to a much lesser extent MDMA also does this, but 5-MeO-DMT is the most powerful “integration aid” we know of). This sounds crazy but it really isn’t. After all, your nervous system is a network of oscillators. It stands to reason that you can change how they interact with one another by fine-tuning their connections and get as a result decoupling of vibrations (e.g. SSRIs), or coupling only between vibrations of a specific frequency (e.g. stimulants and depressants), or more coupling in general (e.g. psychedelics). In particular, 5-MeO-DMT does seem to cause a massively effective kind of fractal coupling, where every vibration can get in tune with every other vibration. And recall, since a lot of our inner world simulation is about representing “external reality”, this effect can give rise to the feeling that you can now instantly communicate with other parts of reality as a whole. This, from my point of view, is merely misinterpreting the experience by imagining that you have direct access to your surroundings.

At 34:52 Leo explains that you just need 5-MeO-DMT to experience these awakenings. And yet, he also claims that everything in reality is imaginary. It is all something that you, as God, are imagining because “you need a story to deny that you are infinite consciousness.” Even though the neurotransmitters are imaginary, you still need to modify them in order to have this experience: “I’m talking about superhuman levels of consciousness. These are not levels of consciousness that you can access sober. You need to literally upgrade the neurotransmitters in your imaginary brain. And yes, your brain is still imaginary, and those neurotransmitters are imaginary. But you still need to upgrade them nevertheless in order to access some of the things I say.”

Needless to say, it’s bizarre that you would need imaginary neurotransmitter-mimicking molecules in your brain in order to realize that all of reality is your own imagination. When you dream, do you need to find a specific drug inside your dream in order to wake up from the dream? Perhaps this view can indeed be steel-manned, but the odds seem stacked against it.

At 38:30 he starts talking about his pornography collection. He assembles nude images of women, not only to relieve horniness, but also as a kind of pursuit of aesthetics. Pictures of nude super-models are some of the most beautiful things a (straight) man can see. He brings this up in order to talk about how he then at some point started exploring watching these pictures on 5-MeO-DMT. Recollecting this brings him to tears because of how beautiful the experiences were. He states “you’ve never really seen porn until you’ve seen it on 5-MeO-DMT.” He claims that he started to feel that this way he really felt that it is you (God) that is beautiful, which is manifested through those pictures.

A robust finding in the psychology of sexual attraction is that symmetry in faces is correlated with attractiveness. Indeed, more regular faces tend to be perceived as more beautiful. Amazingly, you can play with this effect by decorating someone’s face with face-paint. The more symmetrical the pattern, the more beautiful the face looks (and vice-versa). Arguably, the effect Leo is describing where people who are already beautiful become unbelievably pretty on 5-MeO-DMT involves embedding high-dimensional symmetries into the way you render them in your world-simulation. A lesser, and perhaps more reliable, version of this effect happens when you look at people on MDMA. They look way more attractive than what they look like sober.

Leo then brings up (~41:30) that he started to take 5-MeO-DMT on warm baths as well, which he reassures us is not as dangerous as it sounds (not enough water to drown if he experiences a whiteout). [It’s important to mention that people have died by taking ketamine on bath tubs; although a different drug, it is arguably still extremely dangerous to take 5-MeO-DMT alone on a bathtub; don’t do it]. He then has an incredible awakening surrendering to God consciousness in the bathtub, on 5-MeO-DMT, jerking off to beautiful women in the screen of his laptop. He gets a profound insight into the very “nature of desire”. He explains that it is very difficult to recognize the true nature of desire while on a normal level of consciousness because our desires are biased and fragmented. When “your consciousness becomes infinite” those biases dissolve, and you experience desire in its pure form. Which according to his direct experience turned out to be “desire for God, desire for myself”. And this is because you are, deep down “infinite love”. When you desire a husband, or sex, or whatever, you are really desiring God in disguise. But the problem is that since your path to God is constrained by the form you desire, your connection to God is not stable. But once you have this experience of complete understanding of what desire is, you finally get your desire fully quenched by experiencing God’s love.

This is a very deep point. It is related to what I’ve sometimes called the “most important philosophical question“, which is: is valence a spiritual phenomenon or spirituality a valence phenomenon? In other words, do we find experiences of God blissful because they have harmony and symmetry, or perhaps is it the other way around, where even the most trivial of pleasures, like drinking a good smoothy, feels good because it temporarily “gets you closer to God”? I lean towards the former, and that in fact mystical experiences are so beautiful because they are indeed extremely harmonious and resonant states of consciousness, and not because they take you closer to God. But I know very smart people who can’t decide between these views. For example, my friend Stuart Garvagh writes: 

What if the two options are indistinguishable? Suppose valence is a measure of the harmony/symmetry of the object of consciousness, and the experience of “Oneness” or Cosmic Consciousness is equivalent to having the object of consciousness be all of creation (God‘s object), a highly symmetrical, full-spectrum object (full of bliss, light, love, beingness, all-knowledge, empty of discernible content or information). All objects of consciousness are distortions (or refractions, or something) of this one object. Happiness is equivalent to reducing or “polishing-out” these distortions. Thus, what appears to be just the fact of certain states being more pleasant than others is equivalent to certain states being closer to God‘s creation as a whole. Obviously this is all pure speculation and just a story to illustrate a point, but I could see it being very tough to tease apart the truth-value of 1 and 2. Note: I’m fairly agnostic myself, but lean towards 2 (bliss is the perfume of “God realizing God” or the subject of experience knowing Itself). I would very much love to have this question answered convincingly!

At 50:00 Leo says that “everything I’ve described so far is really a prelude to the real heart of awakening, which is the discovery of love. […] I had already awakened to love a number of times, but this was deeper. By the two week mark the love really started to crack open. Infinite self-love. You are drowning on this love.” He goes on to describe how at this point he was developing a form of telepathy that allowed him to communicate with God directly (which is, of course, a way of talking to himself as he is God already). It’s just a helpful way to further develop. And what God was showing him was how to receive self-love. It was so much at first he couldn’t handle it. And so he went through a self-purification process.

An interesting lens with which to interpret this experience of purification is that of neural annealing. Each 5-MeO-DMT experience would be making Leo’s nervous system resonate in ways in new ways, slowly writing over previous patterns and entraining the characteristic high-symmetry patterns of the state. Over time, the nervous system adjusts its weights in order to be able to handle that resonance without getting its patterns over-written. In other words, Leo has been transforming his nervous system into a kind of high-valence machine, which is of course very beneficial for intrinsic feelings of wellbeing (though perhaps detrimental to one’s epistemology).

55:00: He points out that unlike addictive drugs, he actually had to push himself very hard to continue to take 5-MeO-DMT everyday for 30 days. He stopped wanting to do it. The ego didn’t want it. And yes, it was pleasurable once he surrendered on every session, but it was difficult, heavy spiritual work. He says that he could only really do this because of years of practice with and without psychedelics, intense meditation, and a lot of personal development. And because of this, he explains his 5-MeO experiences felt like “years of spiritual work condensed into a single hour.” He then says that God will never judge you, and will help you to accept whatever terrible things you’ve done. And many of his subsequent trips were centered around self-acceptance. 

Following the path of progressive neural annealing, going deeper and deeper into a state of self-acceptance can be understood as a deeper harmonization of your nervous system with itself.

At 1:01:20, Leo claims to have figured out what the purpose of reality truly is: “Reality is a contest for who can love who more. That’s really what life is about when you are fully conscious. […] Consciousness is a race for who can love who more. […] An intelligent fully conscious consciousness would only be interested in love. It wouldn’t be interested in anything else. Because everything else is inferior. […] Everything else is just utter silliness!”

I tend to agree with this, though perhaps not in an agentive way. As David Pearce says: “the pleasure-pain axis discloses the universe’s intrinsic value function.” So when you’ve annealed extremely harmonious patterns and do not get distracted by negative emotion, naturally, all there is left to do is maximize love. Unless we mess up, this is the only good final destiny for the cosmos (albeit perhaps it might take the form of a Hedonium shockwave, which at least in our current human form, sound utterly unappealing to most people).

1:06:10 “[God’s love] sparks you to also want to love it back. You see, it turns into a reciprocal reaction, where it is like two mirrors that are mirroring light between each other like a laser beam that is bouncing between two mirrors. And it’s bouncing back and forth and back and forth. And as it bounces back and forth it becomes more and more concentrated. And it strengthens. And it becomes more coherent. And so that’s what started happening. At first it started out as just a little game. Like ‘I love you, I love you, I love you’. A little game. It sounds like it’s almost like childish. And it sort of was. But then it morphed from being this childish thing, into being this serious existential business. This turned into the work. This was the true awakening. Is that with the two mirrors, you know, first it took a little while to get the two mirrors aligned. Because you know if the two mirrors are not perfectly aligned, the laser beam will kind of bounce back and forth in different directions. It’s not going to really concentrate. So that was happening at first. […] The love started bouncing back and forth between us, and getting stronger and stronger. […] Each time it bounces back to me it transforms me. It opens me up deeper. And as it opens me up deeper it reveals blockages and obstacles to my capacity to love.”

Now this is a fascinating account. And while Leo interprets it in a completely mystical way, the description also fits very well an annealing process where the nervous system gets more and more fine-tuned in order to be able to contain high levels of coherent energy via symmetry. Again, this would be extremely high-valence as a consequence of the Symmetry Theory of Valence. Notice that we’ve talked about this phenomenon of “infinite mirrors” on psychedelics since 2016 (see: Algorithmic Reduction of Psychedelic States).

At ~1:09:30 he starts discussing that at this point he was confronted by God about whether he was willing to love the holocaust, and rape, and murder, and bullies, and people of all sorts, even devil worshipers. 

Two important points here. First, it is a bit ambiguous whether Leo here is using the word “love” in the sense of “enjoyment” or in the sense of “loving-kindness and compassion”. The former would be disturbing while the latter would be admirable. I suppose he was talking about the latter, in which case “loving rape” would refer to “being able to accept and forgive those who rape” which indeed sounds very Godly. This radical move is explored in metta (loving-kindness) meditation and it seems healthy on the whole. And second: Why? Why go through the trouble of embracing all the evil and repulsive aspects of ourselves? One interpretation here, coming back to the analysis based on neural annealing, is that any little kink or imperfection caused by negative emotion in our nervous system will create slight symmetry breaking effects on the resonance of the entire system as whole. So after you’ve “polished and aligned the mirrors for long enough” the tiny imperfections become the next natural blockage to overcome in order to maximize the preservation of coherent energy via symmetry.

~1:12:00 Leo explains that the hardest thing to love is your own self-hatred. In the bouncing off of the love between you and God, with each bounce, you find that the parts you hate about yourself reflect an imperfect love. But God loves all of you including your self-hatred. So he pings you about that. And once you can accept it, that’s what truly changes you. “Because when you feel that love, and you feel how accepting it is, and how forgiving it is of all of your evil and of all of your sins… that’s the thing that kills you, that transforms you. That’s what breaks your heart, wide open. That’s what gets you to surrender. That’s what humbles you. That’s what heals you.” Leo then explains that he discovered what “healing is”. And it is “truth and love”. That in order to heal anyone, you need to love them and accept them. Not via sappy postcards and white lies but by truth. He also states that all physical, mental, and spiritual ailments have, at their root, lack of love.

If love is one of the cleanest expressions of high-valence symmetry and resonance, we can certainly expect that inundating a nervous system with it will smooth and clean its blockages, i.e. the sources of neural dissonance. Hence the incredible power of MDMA on healing nervous systems in the short-term. Indeed, positive emotion is itself healing and enhances neural coherence. But where I think this view is incomplete is in diagnosing the terrible suffering that goes on in the world in terms of a lack of love. For instance, are cluster headaches really just the result of lack of self-love? In here must bring back the background assumption of physicalism and make a firm statement that if we fall into illusion about the nature of reality we risk not saving people (and sentient beings more generally) who are really in the depth of Hell. Just loving them without taking the causally-relevant physical action to prevent their suffering is, in my opinion, not true love. Hence the importance of maintaining a high level of epistemic rigor: for the sake of others. (See: Hell Must Be Destroyed).

1:22:30 Leo explains that in this “love contest” with God of bouncing off love through parallel mirrors the love became so deep that for the first time in his life he felt the need to apologize: “I’m sorry for not loving more.” He goes into a sermon about how we are petty, and selfish, etc. and how God loves us anyway. “Real love means: I really love you as you are. And I don’t need anything from you. And especially all those things that you think I want you to change about you, I don’t need you to change. I can accept them all exactly as they are. Because that’s love. And when you realize THAT, that’s what transforms you. It is not that God says that he loves you. He is demonstrating it. It’s the demonstration that transforms you.” Leo expresses that he was then for the first time in his life able to say “thank you” sincerely. Specifically, “thank you for your love”: “This is the point at which you’ve really been touched by God’s love. And at this point you realize that that’s it, that’s the point, that’s the lesson in life. That’s my only job. It’s to love.” And finally, that for the first time in his life he was able to say “I love you” and truly mean it. “And you fall in love with God… but it doesn’t end there.”

An interesting interpretation of the felt-sense of “truly meaning” words like “I’m sorry”, “thank you”, and “I love you” is that at this point Leo has really deeply annealed his nervous system into a vessel for coherent energy. In other words, at this point he is saying and meaning those words through the whole of his nervous system, rather than them coming from a fragmented region of a complex set of competing internal family systems in a scattered way. Which is, of course, the way it usually goes.

1:35:30 Leo explains that at this point he started going into the stage of being able to radiate love. That he was unable to radiate love before. “I love that you are not capable of love. I love that. And when that hits you, that’s what fills you with enough love to overcome your resistance to love that next level thing that you couldn’t love.” Then at ~ 1:38:00 it gets really serious. Leo explains that so far he was just loving and accepting past events and people. But he was then asked by God whether he would be willing to live through the worst things that have happened and will happen. To incarnate and be tortured, among many other horrible things. And that’s what true love really means. “When you see a murder on the TV, you have to realize that God lived through that. And the only reason he lived through that is because it loved it.”

I do not understand this. Here is where the distinction between the two kinds of senses of the word “love” become very important. I worry that Leo has annealed to the version of love with the meaning of “enjoyment” rather than “loving-kindness and compassion”. Because a loving God would be happy to take the place of someone who went through Hell. But would a loving God send himself to Hell if nobody had to in the first place? That would just create suffering out of nothing. So I am confused about why Leo would believe this to be the case. It’s quite possible that there are many maxima of symmetry in the nervous system you can achieve with 5-MeO-DMT, and some of them are loving in the sense of compassionate and others are crazy and would be willing to create suffering out of nothing from a misguided understanding of what love is supposed to be. Again, handle Plutonium with caution.

1:43:00 Leo started wondering “what is reality then?” And the answer was: “It’s infinite consciousness. Infinite formless consciousness. So what happens was that my mind in my visual field as I was in that bathtub. My mind and my visual field focused in on empty space, and I sort of zoomed into that empty space and realized that that empty space is just love”. He then describes a process where his consciousness became more and more concentrated and absorbed into space, each dot of consciousness branching out into more and more dots of consciousness, turning into the brightest possible white light. But when he inquired into what was that white light he kept seeing that there was no end to it, and rather, that each point was always connected to more points. Inquiring further, he would get the response that at the core, reality is pure love. That it wouldn’t be and couldn’t be any other way.

The description sounds remarkably close to the formless jhanas such as “boundless space” and “boundless consciousness”. The description itself is extremely reminiscent of an annealing process, reaching a highly energized state of consciousness nearly devoid of information content and nearly perfectly symmetrical. The fact that at this incredibly annealed level he felt so much love supports the Symmetry Theory of Valence.

147:28 – And after Leo realizes that “Of course it is love!” he says that’s when the fear comes: “Because then what you realize is that this is the end. This is the end of your life. You are dead. If you go any further you are dead. Everything will disappear. Your family, your friends, you parents, all of it is completely imaginary. And if you stop imagining it right now, it will all end. If you go any further into this Singularity, you will become pure, formless, infinite, love for ever, loving itself forever. And the entire universe will be destroyed as if it never existed. Complete nothingness. Complete everythingness. You will merge into everyone.”

This sounds like the transition between the 6th and 7th Jhana, i.e. between “boundless consciousness” and “nothingness”. Again, this would be the result of further loss of information via an annealing process, refining the symmetry up to that of a “point”. Interestingly, Mike Johnson in Principia Quallia points out that as symmetry approaches an asymptote of perfection you do get a higher quality of valence but at the cost of reduced consciousness. This might explain why you go from “the brightest possible love” to a feeling of nothingness at this critical transition.

1:48:25: “…You will merge into everyone. Your mother, your father, your children, your spouse, Hitler, terrorists, 9/11, Donald Trump, rape, murder, torture, everything will become pure infinite love, merging completely into itself, there will be no distinction between absolutely anything, and that will be the end. And you will realize what reality is. Infinite consciousness. Love. God. And you will realize that everything in your life from your birth to this point has just been some imaginary story. A dream that was design to lead you to pure absolute infinite love. And you will rest in that love forever. Forever falling in love with yourself. Forever making love to yourself. Forever in infinite union. With every possible object that could ever exist. Pure absolute, omnipotent, omniscient, perfect, intelligent, consciousness. Everything that could ever possibly be, is you. And THAT is awakening. When you are this awake, you are dead. And you have no desire for life. There is no physical existence. There is no universe. Nothing remains. Your parents, and your spouse, and your children, they don’t stay back and keep living their lives, enjoying their life without you while your body drops dead. No, no, no, no, no. This is much more serious than that. If you do this. If you become infinite love, you will take everybody with you. There will not be anybody left. You will destroy the entire universe. Every single sentient being will become you. They will have no existence whatsoever. Zero. They will die with you. They will all awaken with you. It’s infinite awakening. It’s completely absolute. There will not be anything left. You will take the entire universe with you. Into pure oneness. THAT’S awakening.”

This is not the first time I hear about this kind of experience. It certainly sounds extraordinarily scary. Though perhaps a negative utilitarian would find it to be the ultimate relief and the best of all possible imaginable outcomes. With the human survival instinct, and quite possibly a body fully aroused with the incredible power of 5-MeO-DMT, this is bound to be one of the most terrifying feelings possible. It’s quite likely that it may be one element of what makes “bad 5-MeO-DMT experiences” so terrifying. But here we must recall that the map is not the territory. And while an annealing process might slowly write over every single facet of one’s model of reality and in turn making them part of a super-cluster of high-dimensional resonance that reflects itself seemingly infinitely, doing this does not entail that you are in fact about to destroy the universe. Though, admittedly, it will surely feel that way. Additionally, I would gather that were it possible to actually end the universe this way, somebody, somewhere, in some reality or another, would have already done so. Remember that if God could be killed, it’d be dead already.

1:52:01: “And I didn’t go there! As you can tell, since I’m still sitting here. I’m not there. I was too afraid to go there. And God was fine with it. It didn’t push me. But that’s not the end of the story! It’s still just the beginning.” He then goes on to explain that a part of him wanted to do it and another part of him didn’t want to. He says it got really loopy and weird; this really shook him. That God was beckoning him to go and be one forever, but he was still ambivalent and needed some time to think about it. He knew it would make no difference, but he still decided to ‘make preparations’ and tell his family and friends that he loves them before moving forward with a final decision to annihilate the universe. By the time he had done that… he had stopped taking 5-MeO-DMT: “The experiences had gotten so profound and so deep… this was roughly the 25th or 27th day of this whole 30 day process. I swore off 5-MeO-DMT and said ‘Ok I’m not doing any more of this shit. It’s enough'”. He explains that by this time the drug was making him feel infinite consciousness when waking up (from sleep) the next day. He felt the Singularity was sucking him into it. It felt both terrifying and irresistible. Every time he would go to sleep it would suck him in really strongly, and he kept resisting it. He would wake up sweaty and in a panic. He was tripping deeper in his sleep than in the bathtub. He couldn’t sleep without this happening, and it kept happening for about 5 days. “I just want to get back to normal. This is getting freaky now.” 

I’ve heard this from more than a couple people. That is, that when one does 5-MeO-DMT enough times, and especially within a short enough period of time, the “realizations” start to also happen during sleep in an involuntarily way. One can interpret this as the annealing process of 5-MeO-DMT now latching on to sleep (itself a natural annealing process meant to lessen the technical debt of the nervous system). Even just a couple strong trips can really change what sleep feels like for many days. I can’t imagine just how intense it must have been for Leo after 25 days straight of using this drug.

2:01:40 – Leo explains that when he was dozing off with a blanket on his living room (terrified of sleeping on his bed due to the effect just described) he experienced a “yet deeper awakening” which involved realizing that all of his previous awakenings were just like points and that the new one was like a line connecting many points. “Everything I’ve said up to this point were just a single dimension of awakening. And then what I broke through to is a second dimension. A second dimension of awakening opened up. This second dimension is completely unimaginable, completely indescribable, cannot be talked about, cannot be thought about. And yet it’s there. In it, are things that are completely outside of the physical universe that you cannot conceive or imagine.” He goes on to explain that there are then also a third, fourth, fifth, etc. dimensions. And that he believes there is an infinite number of them. He barely even began to explore the second dimension of awakening, but he realized that it goes forever. It kept happening, he had intense emotional distress and mood swings. But gradually after five more days it subsided, and he started to be able to sleep more normally. “And I’ve been working to make sense of all of this for the last couple of weeks. So that’s what happened.”

Alright, this is out of my depth and I do not have an interpretation of what this “second dimension of awakening” is about. If anyone has any clue, please leave a comment or shoot me an email. I’m as as confused as Leo is about this.

~2:05:00 – Leo confesses he does not know what would happen if he went through with joining the Singularity and mentions that it sounds a bit like Mahasamādhi. He simply has not answers at this point, but he asserts that the experience has made him question the extent of the enlightenment of other teachers. It also has made him more loving. But still, he feels frustration: “I don’t know what to do from here.”

And neither do I. Do you, dear reader?

Postscript: In the last 10 minutes of the video Leo shares a heart warming message about how reality is, deep down, truly, “just love” and that him saying this may be a seed that will blossom into you finding this out for yourself at some point in the future. He ends by cautioning his audience to not believe as a matter of fact that this is the path for everyone. He suggests that others should just use his examples from his own journey as examples rather than an absolute guide or how-to for enlightenment. He asks his audience to make sure to question the depth of their own awakening – to not believe that they have reached the ultimate level. He admits he has no idea whether there is an ultimate level or not, and that he still has some healing to do on himself. He remains dissatisfied with his understanding of reality.


Thank you for reading!

THE END

Geometry Through the Eyes of Felix Klein

Excerpt from Visual Complex Analysis (1997) by Tristan Needham (pgs. 30-34)

Geometry Through the Eyes of Felix Klein

Even with the benefit of enormous hindsight, it is hard to introduce complex numbers in a compelling manner. Historically, we have seen how cubic equations forced them upon us algebraically, and in discussing Cotes’ work we saw something of the inevitability of their geometric interpretation. In this section we will attempt to show how complex numbers arise very naturally, almost inevitably, from a careful re-examination of plane Euclidean geometry.[10]

[…]

Although the ancient Greeks made many beautiful and remarkable discoveries in geometry, it was two thousand years later that Felix Klein first asked and answered the question, “What is geometry?”

Let us restrict ourselves from the outset to plane geometry. One might begin by saying that this is the study of geometric properties of geometric figures in the plane, but what are (i) “geometric properties”, and (ii) “geometric figures”? We will concentrate on (i), swiftly passing over (ii) by interpreting “geometric figure” as anything we might choose to draw on an infinitely large piece of flat paper with an infinitely fine pen.

As for (i), we begin by noting that if two figures (e.g., two triangles), have the same geometric properties, then (from the point of view of geometry) they must be the “same”, “equal”, or, as one usually says, congruent. Thus if we had a clear definition of congruence (“geometric equality”) then we could reverse this observation and define geometric properties as those properties that are common to all congruent figures. How, then, can we tell if two figures are geometrically equal?

Consider the triangles in [fig 23], and imagine that they are pieces of paper you could pick up in your hand. To see if T is congruent with T’, you could pick up T and check whether it could be placed on top of T’. Note that it is essential that we be allowed to move in space: in order to place T on top of T˜ we must first flip it over; we can’t just slide T around within the plane. Tentatively generalizing, this suggests that a figure F is congruent to another figure F’ if there exists a motion of F through space that makes it coincide with F’. Note that the discussion suggests that there are two fundamentally different types of motion: those that involve flipping the figure over, and those that do no. Later, we shall return to this important point.fig_23

It is clearly somewhat unsatisfactory that in attempting to define geometry in the plane we have appealed to the idea of motion through space. We now rectify this. Returning to [fig 23], imagine that T and T’ are drawn on separate, transparent sheets of plastic. Instead of picking up just the triangle T, we now pick up the entire sheet on which it is drawn, then try to place it on the second sheet so as to make T coincide with T’. At the end of this motion, each point A on T‘s sheet lies over a point A’ of T’‘s sheet, and we can now define the motion M to be this mapping AA’ = M(A) of the plane to itself.

However, not any old mapping qualifies as a motion, for we must also capture the (previously implicit) idea of the sheet remaining rigid while it moves, so that distances between points remain constant during the motion. Here, then, is our definition:

A motion M is a mapping of the plane to itself such that the distance between any two points A and B is equal to the distance between their images A’ = M(A) and B’ = M(B). (22)

Note that what we have called a motion is often termed a “rigid motion”, or an “isometry”.

Armed with this precise concept of motion, our final definition of geometric equality becomes:

F is congruent to F’, written F ≅ F’, if there exists a motion M such that F’ = M(F). (23)

Next, as a consequence of our earlier discussion, a geometric property of a figure is one that is unaltered by all possible motions of the figure. Finally, in answer to the opening question of “What is geometry?”, Klein would answer that it is the study of these so-called invariants of the set of motions.

One of the most remarkable discoveries of the last century was that Euclidean geometry is not the only possible geometry. Two of these so-called non-Euclidean geometries will be studied in Chapter 6, but for the moment we wish only to explain how Klein was able to generalize the above ideas so as to embrace such new geometries.

The aim in (23) was to use a family of transformations to introduce the concept of geometric equality. But will this ≅-type of equality behave in the way we would like and expect? To answer this we must first make these expectations explicit. So as not to confuse this general discussion with the particular concept of congruence in (23), let us denote geometric equality by ~.

(i) A figure should equal itself: F ~ F’, for all F.

(ii) If F equals F’, then F’ should equal F: F ~ F’F’ ~ F.

(iii) If F and F’ are equal, and F’ and F” are equal, then F and F” should also be equal: F ~ F’ & F’ ~ F”F ~ F”.

Any relation satisfying these expectations is called an equivalence relation.

Now suppose that we retain the definition (23) of geometric equality, but that we generalize the definition of “motion” given in (22) by replacing the family of distance-preserving transformations with some other family G of transformations.

It should be clear that not any old G will be compatible with our aim of defining geometric equality. Indeed, (i), (ii), and (iii) imply that G must have the following very special structure, which is illustrated[11] in [fig 24].

(i) The family G must contain a transformation ε (called identity) that maps each point to itself.

(ii) If G contains a transformation M, then it must also contain a transformation M-1 (called the inverse) that undoes M. [Check for yourself that for M-1 to exist (let alone be a member of G) M must have the special properties of being (a) onto and (b) one-to-one, i.e., (a) every point must be the image of some point, and (b) distinct points must have distinct images.]

(iii) If and N are members of G then so is the composite transformation N ∘ M = (followed by N). This property of G is called closure.

We have thus arrived, very naturally, at a concept of fundamental importance in the whole of mathematics: a family G of transformations that satisfies these three[12] requirements is called a group.fig_24

Let us check that the motions defined in (22) do indeed form a group: (i) Since the identity transformation preserves distances, it is a motion. (ii) Provided it exists, the inverse of a motion will preserve distances and hence will be a motion itself. As for existence, (a) it is certainly plausible that when we apply a motion to the entire plane then the image is the entire plane — we will prove this later — and (b) the non-zero distance between distinct points is preserved by a motion, so their images are again distinct. (iii) If two transformations do not alter distances, then applying them in succession will not alter distances either, so the composition of two motions is another motion.

Klein’s idea was that we could first select a group G at will, then define a corresponding “geometry” as the study of the invariants of that G. [Klein first announced this idea in 1872 — when he was 23 years old! — at the University of Erlangen, and it has thus come to be known as his Erlangen Program.] For example, if we choose G to be the group of motions, we recover the familiar Euclidean geometry of the plane. But this is far from being the only geometry of the plane, as the so-called projective geometry of [fig 24] illustrates.

Klein’s vision of geometry was broader still. We have been concerned with what geometries are possible when figures are drawn anywhere in the plane, but suppose for example that we are only allowed to draw within some disc D. It should be clear that we can construct “geometries of D” in exactly the same way that we constructed geometries of the plane: given a group H of transformations of D to itself, the corresponding geometry is the study of the invariants of H. If you doubt that any such group exists, consider the set of all rotations around the center of D.

The reader may well feel that the above discussion is a chronic case of mathematical generalization running amuck — that the resulting conception of geometry is (to coin a phrase) “as subtle as it is useless”. Nothing could be further from the truth! In Chapter 3 we shall be led, very naturally, to consider a particularly interesting group of transformations of a disc to itself. The resulting non-Euclidean geometry is called hyperbolic or Lobachevskian geometry, and it is the subject of Chapter 6. Far from being useless, this geometry has proved to be an immensely powerful tool in diverse areas of mathematics, and the insights it continues to provide lie on the cutting edge of contemporary research.


[10] The excellent book by Nikulin and Shafarevich [1987] is the only other work we know of in which a similar attempt is made.

[11] Here G is the group of projections. If we do a perspective drawing of figures in the plane, then the mapping from the plane to the “canvas” plane is called a perspectivity. A projection is then defined to be any sequence of perspectivities. Can you see why the set of projections should form a group?

[12] In more abstract settings it is necessary to add a fourth requirement of associativity, namely, A∘ (B∘ C) = (A∘ B)∘ C. Of course for transformations this is automatically true.



See also:

  1. The Hyperbolic Geometry of DMT Experiences (@Harvard Science of Psychedelics Club)
  2. Materializing Hyperbolic Spaces with Gradient-Index Optics and One-Way Mirrors
  3. An Intuitive Explanation of the Symmetry Theory of Valence
  4. Principia Qualia: Part II – Valence
  5. Problems you can solve just by looking at them: The meaning of Noether’s Theorem
  6. Quantifying Bliss

Note: QRI‘s Symmetry Theory of Valence (STV) refers to the claim that valence (the pleasure-pain axis) manifests in the symmetry of the mathematical object that corresponds to each experience such that the mathematical features of that object are isomorphic to the phenomenal character of that experience. Using the lens of Klein’s conception of geometry, one could in turn give to STV a strictly geometrical interpretation. Namely, that the shape of one’s experience will be of high valence when it contains geometric invariants. In addition, Noether’s theorem (one of QRI’s lineages, which states that “every differentiable symmetry of the action of a physical system has a corresponding conservation law”) along with physicalism of consciousness suggests that for every symmetry in the mathematical object that corresponds to consciousness there is a corresponding preserved quantity. Thus, one could posit– assuming that the STV is correct– high-valence states might be extremely energy-efficient in addition to feeling good.

We are currently preparing a paper that ties all of these threads together in a way that, we believe, may turn out to have tremendous explanatory power. In particular, this formal account of valence will be able to explain succinctly a wide range of disparate and exotic empirical phenomena such as:

  1. Why phenomenal symmetry during psychedelic experiences is correlated with more extreme valence values.
  2. How and why Jhanas present the way they do, namely, as having:
    1. Extremely positive valence,
    2. Profound phenomenal simplicity, and
    3. Unusually high levels of energy-efficiency all at once.
  3. The fact that moments of eternity are typically extremely blissful.
  4. Why the phenomenal character of MDMA and 5-MeO-DMT manifest as both extremely symmetrical and high-valence.
  5. Why intense regular stroboscopic stimulation has deep emotional effects.
  6. And so much more…

Stay tuned!


Thanks to Alfredo Valverde de Loyola for pointing me to this excerpt in the book Visual Complex Analysis.

Qualia Production Presents: “The Seven Seals of Security” (and Other Communications from QRI Sweden)

By Maggie Wassinge and Anders Amelin (now QRI Sweden and HR helpers; see previous letters)

CosmicImpact

Jewelry by Anders and Maggie (see: Quantifying Bliss for the reference to “C, D, N”)

Hi everyone!

It’s Anders and Maggie in Stockholm, Sweden, here. Volunteers in human resource coordination for the QRI.

We would like to hereby announce our commitment to donate fifty thousand dollars to the Qualia Research Institute for research related to the mathematical modeling of phenomenological valence.

We are pretty much just your ordinary Swedish transhumanist couple. With a passion for finding out from first principles how things work. We whole-heartedly agree with Elon Musk that at the end of the day, excellence is the only passing grade. Over the last couple of years we have arrived at the solid conclusion that the biggest bonanza in effective altruism could only be realized by first of all solving valence. Symbolically, in comedy form, this is like first spending the necessary computational resources to arrive at the conciseness of 42 as “the answer”, before it can be determined what the right questions must then be. In our book it is with no doubt the Qualia Research Institute which corresponds to “Deep Thought” in what Elon Musk has called “the best philosophy book ever”: The Hitch-Hiker’s Guide to the Galaxy. Seriously here, it is advisable to balance this with a bit of David Pearce also, but indeed we do believe an encouraging “Don’t Panic” is in fact compatible with the laws of nature in this universe. Immense reward is there for those who roll up their sleeves and start working systematically from first principles.

But again, excellence is the only passing grade. The universe is no picnic. It is a field of seemingly infinite potentialities, all of which are open to exploration and exploitation. It is still unknown what the proto-states of sentience are intrinsically like, but it is clear that biological evolution works as an optimization engine for valence polarization. A “passing grade” for a long-term sustainable and prospering technological civilization must involve a universally global first-principles solution to the horrific downside of this: suffering. That solution must be combined with optimal development of the state space of positive valence and intelligence. It seems plausible that experienced negative valence is a computationally economic way for evolution to drive behavior when the implementation is in biochemistry. However, information processing can also be done non-consciously, and it stands to reason that all the informational saliency achieved via negative valence experience can instead be had via non-conscious processes which would be available to future suitably modified embodiments of intelligence.

The QRI is the only real player in this game so far, as our civilization takes its first baby steps towards maturity. In the domain of effective altruism, the Qualia Research Institute today corresponds to what bitcoin was when first launched. The difference is that the QRI doesn’t just promise to be a novel medium of exchange, but a novel competence about the first principles of well-being!

During the couple of years it took for us to come to the above conclusions, we set aside every penny we could spare. That became the fifty thousand we are now committing to the QRI. If enough others with the same visions were to do the same thing, soon enough it could begin adding up to real money. Money which at this foundational stage stands at quite a favorable exchange rate with respect to the ultimate currency of the universe: positive emotional valence.

Infinite bliss to everyone from a couple of Scandinavian old-timers!HEA-2020-01-19

HEA-LENA

High Entropy Alloy (Al + Ti + Cr + Mo + W) and Low-Entropy Non-Alloy (Ti) – made by Anders and Maggie. If non-materialist physicalist idealism (i.e. panpsychism that respects physics) is true, what do these bundles of baryonic matter feel like from the inside?


Letter IV: On Psychonautics

Psychedelic trippers put effort into trying to interpret what it all means ontologically. Plant spirits may be at work, or one taps into the collective unconscious or is simulated by some alien superintelligence.

The QRI could perhaps guide interested psychonauts in the direction of writing more scientifically productive reports.

A scientifically minded tripper needs to start with the realization that human beings are perfect psychonauts because our brains have an enormous excess capacity over what is minimally required to perform any one of the tasks that we do in everyday waking life. The highly unusual aspect of human brains is that they can produce general intelligence. This is rare in nature but when you have it, you assume it to be the normal state of affairs.

Trippers are often in disbelief over the ability of human brains to produce the fantastic content of psychedelic experiences. As if there is suddenly a superpower there which one never uses when sober. How can that be? It must be something supernatural going on, right? Actually, no. Not that we should rule out the “supernatural” a priori but it is not necessary.

The human mind uses a superpower all the time. One which is hidden in plain view, we might say. It is the superpower of selecting from a huge range of possibilities for what the mind could be doing, and homing in on exactly the one choice in every moment that is most appropriate right then and there. When those tight constraints are relaxed the human brain becomes a system which can explore far and wide in qualia state-space.

Intelligence is a phenomenon which uses multiple optimization points to converge on some invariance. At the theoretical efficiency maximum this takes surprisingly (to us) little raw processing power. A jumping spider does not display less strategic and tactical intelligence than a human does when hunting. The spider’s neural network is very much smaller than the human’s but the evolutionary fitness search available for evolving small, numerous and quickly reproducing creatures is much larger than for animals like us. For us it is not so much a question of evolution having optimized what every cell does, but one of having added more and more cells to increase overall performance.

The spider’s brain probably contains far less sub-optimal “spaghetti code” than the human’s. It is possible that the spider has access to exquisitely fine-tuned qualia for the crucial task of sneaking up on big, highly dangerous prey and bringing it down without botching the job. On the other hand, there might not be much opportunity for spiders to evolve general intelligence since they have already done away with everything that is “useless” for their sober everyday lives.

Friendly-jumping-spider-Thomas-Shahan-17exizc

“Does my brain contain less spaghetti code than yours?”

A human brain is a mass of excitation-inhibition “spaghetti” which defies belief. An almost ultimate jack of all trades but master of none which cannot quite produce the hunting skills of the spider but can instead do a billion other things that the spider could not even in principle learn how to do.

It is the billion other things that we could do but don’t, which is the human superpower, not the few things that we actually do on a sober basis. This is a power which can be harnessed for psychonautics. You’ve got an inner-space warp drive in your head. Aptly named. 🖖


Letter V: Exciting Research Leads

Here are some suggestions for titles of essays and research papers the QRI could write if we had the resources.

  1. “Alloy, anneal, quench and temper: Forging a blade to cut mind at the joints”
  2. “Play me like a violin: A compressibility analysis of neuro-acoustic patterns captured during person to person interaction”
  3. “Leadership and consonance: Aggregate neuro-acoustic compressibility as a proxy for computational efficiency of human group intelligence”
  4. “Neural annealing through laughter: Neuro-acoustics of humor as a factor for healthy mental adjustment”
  5. “The tree of music: An annealable branching tuning-fork model for nervous systems”
  6. “Same but different: Suggesting a qualia analogue for the comparative planetology of Earth and Titan”
  7. “Music of life: Consonance, dissonance, noise and symmetry as explanatory elements for evolution from single cells to human minds”
  8. “Compartments of harmony bounded by dissonance: A neuro-acoustic model of domain specificity in cognition”

The Seven Seals of Security or Safety Through Uncertainty – Transhumanist Satire

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Letter VI: Earth as an Engine of Qualia Diversity

Handwaving Johnson & Gómez-Emilsson’s law about the surprisingly large size of qualia state space:

Presume that consciousness and matter are interconnected information structures. Can any useful parallels be drawn from the matter domain of outer space to the consciousness domain of inner space? Consider that planets, as a group, are subject to variation and (anthropic) selection. An interconnection point is provided by observation selection: Certain planetary properties far from the universe median are going to be found by intelligent conscious observers for their own planet of origin. A small subset of conscious observers are the ones who, like humans, have general intelligence and broad curiosity. Those observers are the few who observe more and more aspects of their own planet as well as adjacent space and the state space of matter at large, and ultimately perhaps also of consciousness at large. The evolutionary reproductive selection of such observers is not the default condition of all life but rather it is conditional upon even more unusual properties of their planet of origin than for the average life-bearing planet.

Conclusion: Earth is likely to be a highly unusual planet, and human consciousness is likely to be a highly unusual seat of experience. They are causally linked. A structural property they share could be a high level of diversity but never reaching cosmically global extremes on any single parameter. A Jill of all trades planet is married to a Jack of all trades mind.

While fairly good at impressively many trades, Jack and Jill are master and mistress of none. For a tentative and very loose analogy which may be better than nothing, let’s say planet Earth is like the human mind. The other planets in the Solar System are like altered human minds and some animal minds. Some basic properties like gravity, roundness and rotation are common to all the planets. Corresponding to suggested basic features of biologically evolved sentience, such as valence and some sensory modalities.

Then we follow Slartibartfast to the fjords of Norway. Here we see how Earth differs in diversity compared with the other “animals”. The planet’s surface is an energetic 3-phase regime. Solid crust, liquid water and solid water under highly dynamic conditions. Not widely separated like on Europa but forming extended areas of contact where unusual complexity emerges. It’s worth an award, really. (No, not Belgium…).

Human cognition is like Earth with its’ coasts and mountain ranges. A “just right” quantity and proportionality of ingredients is what allowed self-organization of Earth’s environmental complexity and its’ endurance over time via the mechanism of prolonged core solidification and plate tectonics. An unusual state of affairs in nature. It’s not unexpected in principle, only rare in actual existence. The same may go for evolution of the general cognition accessible to human minds.

A type of mind which is generally competent over multiple domains of agency cannot function as such if not many crucial parameters in its’ architecture fall within a tight range of “just right and not too much nor too little”. Or, in Swedish, “lagom”. If you loosen that constraint, such as by ingesting 5 grams of mushrooms blindfolded, your mind will clearly no longer function on your job or even in your body. But in exchange for giving up on that functionality as agent, you can max out on stuff like… well, it’s beyond words.

General intelligence is not compatible with an easy achievement of extreme states of consciousness, though as a less frequently added mental ingredient for a group intelligence (like human hunter-gatherers) extreme states can be hypothesized to enhance abilities of that group intelligence.

But what does the current human “master of none” in qualia rendering imply for the future of consciousness, and what about cosmic matter beyond the neighboring planets?

Beyond the Solar System we find many types of stars, black holes, dark matter and various ultra-thin, ultra-dense, ultra-cold, or ultra-hot configurations of matter in the wider domain of spacetime. Nature usually has not developed nonliving matter into configurations with even remotely as high a complexity as for living matter, simply because of no evolutionary selection pressures. Some nonbiological matter objects could be strong qualia generators just by chance, though. The Sun comes speculatively and punlessly to mind. Doing an IIT and a CDNS analysis on its’ surface magnetized plasma wave patterns may not be entirely far-fetched. But the big promise for expanding the diversity of actualized sentience comes through engineering. Jack and Jill is the couple who can pull that off, and their offspring can then grow up in that fabulous new landscape of experience. For they can become masters and mistresses. Dominatrices, even. The reason being that while the parents are tightly constrained experientially, the kids need not be.

For an efficiently organized advanced technological civilization, the constraints of being a highly general and resilient intelligence can be placed high up on the group level. Individual seats of experience with the sizes of today’s human or animal brains, say, can then be allowed to render experiential states more specialized to feel meaningful, enjoyable and worthwhile. (A dystopian version could instead generate unimaginable suffering, of course. Need to watch out…).

Earth is by far the most diverse planet in the Solar System, but it does not have the deepest ocean, the tallest mountain, the highest gravity, the hottest days, the most explosive volcanoes or the most intense thunderstorms. Human minds who have only experienced their evolved biologically functional mental states have not reached the consciousness state space equivalents of the extreme environments on the other planets. They have never snowboarded down the tellurobismutite condensate slopes on Maxwell Montes or been ejected on a ballistic trajectory by a sulfur dioxide plume from Tvashtar Patera. These things may be comparable to being a bat or taking psilocybin. As different from sober human experience as they are, they still merely hint at the range of possible experiences in the qualia state space opening up beyond. If all goes well, there will be psychonauts of the future who are children of Earth and able to engineer any form of matter and energy into conscious brain architectures. They would become what Max Tegmark has called “Life 3.0”.

Either that or, in a hopefully not terribly more likely scenario portrayed by imagined future historians, humanity stayed obsessed with the circulation of money to the detriment of all else.

This planet has – or rather had – a problem, which was this: most of the people living on it were unhappy for pretty much of the time. Many solutions were suggested for this problem, but most of these were largely concerned with the movement of small green pieces of paper, which was odd because on the whole it wasn’t the small green pieces of paper that were unhappy.” ― Douglas Adams, The Hitchhiker’s Guide to the Galaxy 🌎


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Earth as an Engine of Qualia Diversity

Neural Annealing: Toward a Neural Theory of Everything

QRI‘s co-founder Michael E. Johnson just posted a piece on neural annealing. This is one of QRI’s most important pieces of content to date. I’m very proud of Mike and the team for pulling this off. You can find the full piece here.



Mike writes:

This is QRI’s unified theory of music, meditation, psychedelics, depression, trauma, and emotional processing; the most challenging (and I think beautiful) thing I’ve written in the last three years. I would really appreciate careful comments.

A few takeaways:


  • Entering high-energy states (i.e., intense emotional states which take some time to ‘process’) is how the brain releases structural stress and adapts to new developments. This is similar to ‘annealing’ in metals, where heat allows atoms to break their bonds, then they search for more stable configurations as they cool.
  • Brains really do need to anneal regularly to pay down their ‘technical debt’, and if they don’t, they grow brittle and neurotic.
  • Meditation, music, psychedelics, exercise, dance, sex, tantric practices, EMDR, and breath work all share the same mechanism: a build-up of rhythmic neural resonance that can push the brain into these high-energy states which produce annealing.
  • Depression is a self-reinforcing perturbation from the natural annealing cycle.
  • Sometimes the brain needs to rapidly halt information propagation across regions to prevent cascading system failure … we call this ‘trauma’. This is a common and serious disruption of the annealing cycle.
  • The core psychological changes driven by psychedelics are best understood in terms of the amount and ‘statistical flavor’ of the energy (rhythmic firing) they add to the brain. Different psychedelics will ‘anneal’ different things.
  • Young brains (and lifelong learners) might not only be more plastic than average, but actually having experience that is objectively more visceral.
  • A unified theory of emotional updating, depression, trauma, meditation, and psychedelics may give us the tools to build a future that’s substantially better than the present.

(A unification of Robin Carhart-Harris and Karl Friston’s REBUS annealing model, with Selen Atasoy’s Connectome-Specific Harmonic Waves paradigm.)

Two Recent Presentations: (1) Hyperbolic Geometry of DMT Experiences, and (2) Harmonic Society

Here are two recent talks I gave. The first one is a talk about the Hyperbolic Geometry of DMT Experiences I gave at the Harvard Science of Psychedelics Club in mid-September (2019). And the second talk is about QRI‘s models of art, which took place in June (2019) at a QRI party in the Bay Area.


The Hyperbolic Geometry of DMT Experiences (@Harvard Science of Psychedelics Club)


Description

Andrés Gómez Emilsson from the Qualia Research Institute presents about the Hyperbolic Geometry of DMT Experiences.

At a high-level, this video presents an algorithmic reduction of DMT phenomenology which imports concepts from hyperbolic geometry and dynamic systems theory in order to explain the “weirder than weird” hallucinations one can have on this drug. Andrés describes what different levels of DMT intoxication feel like in light of a model in which experience has both variable geometric curvature and information content. The benefit of this model cashes out in a novel approach to design DMT experiences in order to maximize specific desired benefits.

See original article: The Hyperbolic Geometry of DMT Experiences: Symmetries, Sheets, and Saddled Scenes

And the Explain Like I’m 5 version: ELI5 “The Hyperbolic Geometry of DMT Experiences”

Presentation outline:

  • Thermometers of Experience
  • The Leaf Metaphor
  • Introduction to Hyperbolic Geometry
  • DMT Levels
  • Level 1: Threshold (& Symmetry Hotel)
  • Level 2: Chrysanthemum
  • Level 3: Magic Eye (& Crystal Worlds)
  • Level 4: Waiting Room
  • Level 5: Breakthrough
  • Level 6: Amnesia
  • Energy – Complexity Landscape
  • Dynamic Systems
  • Fixed Point
  • Limit Cycles
  • Chaos
  • Noise Driven Structures
  • Turbulence
  • Conclusion
  • Super-Shulgin Academy
  • Atman Retreat
  • Wrap-Up

About the speaker: Andrés studied Symbolic Systems at Stanford (and has a masters in Computational Psychology, also from Stanford). He has professional experience in data science engineering, machine learning, and affective science. His research at the Qualia Research Institute ranges from algorithm design, to psychedelic theory, to neurotechnology development, to mapping and studying the computational properties of consciousness. Andrés blogs at qualiacomputing.com.

The Qualia Research Institute (QRI) is a non-profit based in the Bay Area close to San Francisco which seeks to discover the computational properties of experience. QRI has a “full-stack approach” to the science of consciousness which incorporates philosophy of mind, neuroscience, and neurotechnology. For more information see: qualiaresearchinstitute.org

The Harvard Science of Psychedelics Club hosts events on psychedelic research, meditation, neuroscience, students sharing their own experiences, and much more.


Credits:

– Wallpaper group 632 rotating along each symmetry element – Nick Xu

– Many of the images are by Paul Nylander: http://bugman123.com/

– The Hyperbolic Honeycomb images and 3D prints are by Henry Segerman, who also has an awesome Youtube channel where he shows 3D printed math. We used his design to print the Honeycombs we were passing around during the lecture: https://www.youtube.com/user/henryseg

– Space-Time Dynamics in Video Feedback: Jim Crutchfield, Entropy Productions, Santa Cruz (1984): https://youtu.be/B4Kn3djJMCE

Many thanks to Andrew Zuckerman and Kenneth Shinozuka for helping organize this event. And thanks to David Pearce, Michael Johnson, Romeo Stevens, Quintin Frerichs, the anonymous trippers, and many others for making this work real.


And here are the slides:

 

Dynamic Systems animations:



Harmonic Society: 8 Models of Art for a Scientific Paradigm of Aesthetic Qualia


Description

Andrés Gómez Emilsson from the Qualia Research Institute gives a presentation about how art works according to modern neuroscience and philosophy of mind.

The video discusses eight different models of art: models 1 through 4 have been discussed in academic literature and the current intellectual zeitgeist, while models 5 through 8 are new, original, and the direct result of recent insights about consciousness as uncovered by modern neuroscience, philosophy of mind, and the work of the Qualia Research Institute.

Abstract:

We start by assuming that there are real stakes in art. This motivates the analysis of this subject matter, and it focuses where we place our gaze. We examine a total of eight models for “what art might be about”, divided into two groups. The first group of four are some of the most compelling contemporary models, which derive their strength from fields such as philosophy of language, economics, evolutionary psychology, and anthropology. These models are: (1) art as a word only definable in a family resemblance way with no necessary or sufficient features, (2) art as social signaling of desirable genetic characteristics, (3) art as Schelling point creation, and (4) art as the cultivation of sacred experiences. These four models, however enlightening, nonetheless only account for what David Marr might describe as the computational level of abstraction while leaving the algorithmic and implementation levels of abstraction unexamined. They explain what art is about in terms of why it exists and what its coarse effects are, but not the nature of its internal representations or its implementation. Hence we propose a second group of four models in order to get a “full-stack” view of art. These models are: (5) art as a tool for exploring the state-space of consciousness, (6) art as a method for changing the energy parameter of experience, (7) art as activities that induce neural annealing (which implements novel valence modulation, i.e. surprising pain/pleasure effects), and (8) art as an early prototype of a future affective language that will allow diverse states of consciousness to make sense of each other. These frameworks address how art interfaces with consciousness and how its key valuable features might be implemented neurologically. We conclude with a brief look at how embracing these new paradigms could, in principle, lead to the creation of a society free from suffering and interpersonal misunderstanding. Such a society, aka. Harmonic Society, would be designed with the effect of guaranteeing positive valence interactions using principles from a post-Galilean science of consciousness.

———————–

The 8 models of art are:

1. Art as family resemblance (Semantic Deflation)

2. Art as Signaling (Cool Kid Theory)

3. Art as Schelling-point creation (a few Hipster-theoretical considerations)

4. Art as cultivating sacred experiences (self-transcendence and highest values)

5. Art as exploring the state-space of consciousness (ϡ☀♘🏳️‍🌈♬♠ヅ)

6. Art as something that messes with the energy parameter of your mind (ꙮ)

7. Art as puzzling valence effects (emotional salience and annealing as key ingredients)

8. Art as a system of affective communication: a protolanguage to communicate information about worthwhile qualia (which culminates in Harmonic Society).


The presentation is based on an essay published in the Berlin-based art magazine Art Against Art (see: Issue #6).

Article is posted online here: Models 1 & 2, 3 & 4, 5 & 6, 7 & 8.


See more about the Qualia Research Institute at: https://www.qualiaresearchinstitute.org/

Andrés blogs at Qualia Computing: Top 10 Qualia Computing Articles


Infinite bliss!!!


And here are the slides:

Kaleidoscopic Integration: Annealing, Symmetry, and the Information Theory of Experience

Symmetric_pattern_drifting

HP: What exactly is “symmetrical texture repetition”?

JE: Symmetrical texture repetition is just one of many complex visual distortions or alterations which consistently occur throughout psychedelic experiences on substances such as LSD, Psilocin, Ayahuasca, Mescaline, 2C-B, 2C-E and many others.

It can be described as the organization of rough textures within the external environment becoming mirrored repeatedly over its own surface in an extremely intricate and symmetrical fashion that is consistent across itself. This remains at an unchanging level of extremely high detail and visual clarity within both a person’s direct line of visual focus and peripheral vision.

 

As these repeating textures are generated they begin to give rise to a huge array of abstract forms, imagery, geometry and patterns that are perceived to be embedded within and across the symmetry.

 

Interview with Chelsea Morgan, a prolific and talented psychedelic replication artist

Towel (1)

Towel texture enhancement by Chelsea Morgan. Source.

Ice_by_Chelsea_Morgan

Ice symmetrical texture repetition by Chelsea Morgan. Source.

How it feels like to symmetry-unify from the inside, a case study:

Onion Article Headline 2016: Synesthetic Couch-Texture Not Quite Ready to Merge with Lamp Turned Space-Filling Line System, Says It Needs to Make Itself More Spiky First

 

Inside Alice’s acid-filled brain today, we are now about to experience for the 6th time or so how various blobs of textures are trying to merge into a coherent super structure. According to local sources, Alice is currently feeling a sense of awe and anticipation as the two big texture clusters in her field of vision are beginning to interact with each other. She is excited to notice that one of them is “calling” the other into it, and giving it ideas on how to “plug in geometrically” with it.

 

Alice, who reportedly took 160 micrograms of LSD roughly 3 hours ago, narrates how it felt like to make a super-symmetrical system in her visual-kinesthetic field for the 5th time:

 

“I don’t know if this was the result of alien intelligences messing up with my brain, perhaps a mystical vision about how my ancestors’ experiences connect to mine, or if it was just a strange quantum-entanglement phenomenon in consciousness currently undocumented in the scientific literature, but duude! That one time the couch texture blob made itself more spiky in order to merge with the the space-filling lamp… that was awesome. I look forward to it happening again, but now also including the carpet, walls, and my hands. Leave no texture behind – the resonant symmetry super-structure can make room for everyone.” – Said Alice, in closing.

Psychedelic Symmetry: A Window Into the Information-Theoretic Properties of Experience?

My friend Tim who had not done LSD for many years, responded to this sudden 5 hit dose by going into a state of complete dissociation. He lay down on the forest floor with glassy eyes, muttering “It is TOO beautiful! It is TOO beautiful!” and he did not respond to me, even when I stared him straight in the face. He reported afterwards that he found himself in a giant Gothic cathedral with the most extravagantly elaborate and brightly painted ornamental decorations all around him. This too can be seen as an extreme form of the regularization discussed above. Under the influence of this powerful dose, Tim’s visual brain could no longer keep up with the massive irregularity of the forest around him, and therefore presented the forest in simplified or abbreviated form, as the interior of a Gothic cathedral. It captures the large geometry of a ground plane that supports an array of vertical columns, each of which fans out high overhead to link up into an over-arching canopy of branches. The only difference is that in the Gothic cathedral the trees are in a regular geometrical array, and each one is a masterpiece of compound symmetry, composed of smaller pillars of different diameters in perfectly symmetrical arrangements, and studded with periodic patterns of ribs, ridges, or knobby protuberances as a kind of celebration of symmetry and periodicity for their own sake. There is a kind of geometrical logic expressed in the ornamental design. If part of the cathedral were lost or destroyed, the pattern could be easily restored by following the same logic as the rest of the design. In information-theoretic terms, the Gothic cathedral has lots of redundancy, its pattern could be expressed in a very much simpler compressed geometrical code. In Tim’s drug-addled brain his visual system could only muster a simple code to represent the world around him, and that is why Tim saw the forest as a Gothic cathedral. Under normal conditions, the additional information of irregularity, or how each tree and branch breaks from the strict regularity of the cathedral model of it, creates the irregular world of experience that we normally see around us. This suggests that the beautiful shapes of ornamental art are not the product of the highest human faculty, as is commonly supposed, but rather, ornamental art offers a window onto the workings of a simpler visual system, whose image of the world is distorted by artifacts of the representational scheme used in the brain. The Gothic cathedral gives a hint as to how the world might appear to a simpler creature, a lizard, or a snake, to whom the world appears more regular than it does to us, because its full irregularity is too expensive to encode exhaustively in all its chaotic details. Of course the flip-side of this rumination is that the world that we humans experience, even in the stone-cold sober state, is itself immeasurably simpler, more regular and geometric, that the real world itself, of which our experience is an imperfect replica. In the words of William Blake, “If the doors of perception were cleansed, everything would appear to man as it is, infinite.”

– “The Grand Illusion” by Cognitive Scientist Steven Lehar

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What is the information content of a gothic cathedral? What percentage of it needs to burn down to make it impossible to reconstruct from the ruins alone?

Why Does Any of This Matter? The Deceptively Profound Implications of Psychedelic Symmetry According to Cognitive Scientist Steven Lehar

But there was one aspect of the LSD experience that had me truly baffled, and that was the fantastic symmetries and periodicities that were so characteristic of the experience. What kind of neural network model could possibly account for that? It was an issue that I grappled with for many months that stretched into years. In relation to Grossberg’s neural network, it seemed that the issue concerned the question of what happens at corners and vertices where contours meet or cross. A model based on collinearity alone would be stumped at image vertices. And yet a straightforward extension of Grossberg’s neural network theory to address image vertices leads to a combinatorial explosion. The obvious extension, initially proposed by Grossberg himself, was to posit specialized “cooperative cells” with receptive fields configured to detect and enhance other configurations of edges besides ones that are collinear. But the problem is that you would need so many different specialized cells to recognize and complete every possible type of vertex, such as T and V and X and Y vertices, where two or more edges meet at a point, and each of these vertex types would have to be replicated at every orientation, and at every location across the whole visual field! It just seemed like a brute-force solution that was totally implausible.

Then one day after agonizing for months on this issue, my LSD observations of periodic and symmetrical patterns suddenly triggered a novel inspiration. Maybe the nervous system does not require specialized hard-wired receptive fields to accomodate every type of vertex, replicated at every orientation at every spatial location. Maybe the nervous system uses something much more dynamic and adaptive and flexible. Maybe it uses circular standing waves to represent different vertex types, where the standing wave can bend and warp to match the visual input, and standing waves would explain all that symmetry and periodicity so clearly evident in the LSD experience as little rotational standing waves that emerge spontaneously at image vertices, and adapt to the configuration of those vertices. Thanks to illegal psychotropic substances, I had stumbled on a staggeringly significant new theory of the brain, a theory which, if proven right, would turn the world of neuroscience on its head! My heart raced and pounded at the implications of what I had discovered. And this theory became the prime focus of my PhD thesis (Lehar 1994), in which I did computer simulations of my harmonic resonance model that replicated certain visual illusions in a way that no other model could. I had accomplished the impossible. I had found an actual practical use and purpose for what was becoming my favorite pass-time, psychedelic drugs! It was a moment of glory for an intrepid psychonaut, a turning point in my life. Figure 2.6 shows a page from my notebook dated October 6 1992, the first mention of my new theory of harmonic resonance in the brain.

– “The Grand Illusion” by Cognitive Scientist Steven Lehar

lehar_2_6


Featured image credit: Simon Haiduk

Carhart-Harris & Friston 2019 – REBUS and the Anarchic Brain

Reposted from Enthea with permission from the writer: 


Drs. Robin Carhart-Harris and Karl Friston recently published a beautiful paper – REBUS and the Anarchic Brain (a).

It’s great for two reasons:

  1. It presents a plausible unified theory of how psychedelics work.
  2. It’s a wonderful jumping-off point into the literature. Every paragraph is full of pointers to research that’s come out in the last 5 years, and boy are there a lot of rabbit holes to go down – it’s filled out my reading list for the next several months.

Carhart-Harris is the director of Imperial College London’s newly minted Centre for Psychedelic Research; Friston is a famous neuroscientist.

REBUS is a (somewhat dubious) acronym for RElaxed Beliefs Under pSychedelics. The basic idea: psychedelics reduce the weight of held beliefs and increase the weight of incoming sensory input, allowing the beliefs to be more readily changed by the new sensory information.

REBUS pulls together Carhart-Harris’ Entropic Brain theory and Friston’s Free Energy Principle, both of which relate to the hierarchical predictive coding model of cognition. There’s a lot of jargon & nuance here, but the essential idea of hierarchical predictive coding is pretty straightforward:

  • The brain generates mental models that predict upcoming sensory inputs. (The predictions are called “priors,” as in “prior beliefs.”)
  • These predictive models are layered on top of each other in a hierarchy – the higher levels send predictions down the hierarchy; the lower levels report sense data upwards.
  • In cases where the model’s top-down predictions do not match the bottom-up sensory input, the model either (a) updates its priors based on the new sense data, or (b) ignores the sense data and maintains its priors.

(Scott Alexander’s review of Surfing Uncertainty has a lot more on predictive coding.)

Carhart-Harris & Friston theorize that the main thing psychedelics are doing is relaxing the weight of the brain’s top-down prediction-making (“REBUS”) and increasing the weight of the bottom-up sense information (“the Anarchic Brain”). This allows bottom-up information to have more influence on our conscious experience, and also on the configuration of the hierarchy overall.

Carhart-Harris & Friston analogize this process to annealing – heating up a metal dissolves its crystalline structure, then a new structure recrystallizes as the metal cools:

The hypothesized flattening of the brain’s (variational free) energy landscape under psychedelics can be seen as analogous to the phenomenon of simulated annealing in computer science – which itself is analogous to annealing in metallurgy, whereby a system is heated (i.e., instantiated by increased neural excitability), such that it attains a state of heightened plasticity, in which the discovery of new energy minima (relatively stable places/trajectories for the system to visit/reside in for a period of time) is accelerated (Wang and Smith, 1998).

Subsequently, as the drug is metabolized and the system cools, its dynamics begin to stabilize – and attractor basins begin to steepen again (Carhart-Harris et al., 2017). This process may result in the emergence of a new energy landscape with revised properties.

Psychedelics “heat up” the brain, increasing plasticity and weakening the influence of prior beliefs. As the psychedelic stops being active, the brain “cools” – the hierarchy re-forms, though perhaps in a different configuration than the pre-psychedelic configuration.

This explains how psychedelic trips can cause changes that last long after the substance has exited the body – in those cases, the psychedelic facilitated a change in the organization of the brain’s cognitive hierarchy.

Psychedelic therapy is showing promise for mental disorders associated with too-rigid thought patterns – depression, anxiety, addictions, maybe OCD, maybe eating disorders. In predictive-coding lingo, “disorders that may rest on particularly rigid high-level priors that dominate cognition.”

In these disorders, new information can’t revise the existing story of how things are, because strong priors suppress the new info before it can update anything.

The REBUS model straightforwardly explains how psychedelics help with disorder like this – by relaxing the strong top-down priors and boosting the bottom-up inputs, bottom-up inputs have more ability to effect the system. Here’s an illustration from the paper:

rebus-schema

The top sketch is a brain where strong top-down priors dominate. New sensory inputs are suppressed and can’t update the hierarchy. The bottom sketch is the same brain while on a psychedelic – the top-down priors have been relaxed and bottom-up sensory information flows more freely through the system, causing a bigger impact.

Okay, nice theory, but can we observe this in the brain? Is there any evidence for it?

Carhart-Harris & Friston place the default mode network at top of the brain’s predictive hierarchy. The default mode network is the network of brain regions that’s most active when the brain isn’t engaged with any specific task. It also appears to be the seat of one’s sense of self. The default mode network is intensely relaxed by strong psychedelic experiences – this is subjectively felt as ego dissolution, and allows for the propagation of bottom-up sense data (which are also boosted by psychedelics).

Carhart-Harris & Friston identify two mechanisms by which psychedelics may relax the default mode network – activation of 5-HT2AR serotonin receptors (there are lots of these receptors in the default mode network), and disruption of α and βwave patterns, which seem to propagate top-down expectations through the brain (and are correlated with default mode network activity).

In addition to the brain-scan-style evidence they cite throughout the paper, Carhart-Harris & Friston dedicate a long section to behavioral evidence (“Behavioral Evidence of Relaxed Priors under Psychedelics”). Briefly, there are several studies showing that surprise & consistency-making responses to sensory stimuli are reduced while on psychedelics, which is what we’d expect if the influence of top-down priors was lessened.

To sum up, REBUS and the Anarchic Brain places psychedelics in a predictive coding framework to give a unified theory of what psychedelics do – they decrease the influence of top-down prediction-making and increase the influence of bottom-up sense data. The theory has the nice quality of tying many disparate psychedelic phenomena together with an underlying explanation of what’s going on. Plus, it gives a brain-based explanation for why psychedelic therapy is helpful for disorders like depression, anxiety, and addiction.



See also: Mike Johnson’s pieces A Future for Neuroscience and The Neuroscience of Meditation which summarize a lot of the research by the Qualia Research Institute (QRI) on this topic. In particular, much like this paper by Carhart-Harris and Friston, at QRI we’ve been working on integrating the neuroscientific paradigms of Entropic Brain, Connectome-Specific Harmonic Waves, Predictive Coding, and our own contribution of Neural Annealing into a unified theory of psychedelic action for a number of years.

Our first mention of Neural Annealing in relation to psychedelics was in Algorithmic Reduction of Psychedelic States in 2016, and we are pleased to see that the concept is becoming a live idea in academic neuroscience in 2019.*

From our point of view, an extremely promising area of research that mainstream neuroscience has yet to explore is the Symmetry Theory of Valence. In particular, we claim that the very reason why Neural Annealing improves not only global control, belief, and behavioral consistency, but also mood and sense of wellbeing is because it smooths and symmetrifies your neural patterns of activation. Will this turn out to become part of mainstream neuroscience in the future? Well, since QRI was calling Neural Annealing years in advance, perhaps in retrospect you’ll also see that we were on the money when it came to the mathematics of valence. Only time (and funding) will tell.


*It should be noted that unbeknownst to us Steven Lehar might be the first person to discuss neural annealing in the context of psychedelic states of consciousness. In his 2010 book “The Grand Illusion” he talks about annealing on LSD and ketamine. Here are some key articles about it: Free-Wheeling Hallucinations, The Resonance and Vibration of [Phenomenal] Objects, The Phenomenal Character of LSD + MDMA, and From Point-of-View Fragmentation to Global Visual Coherence: Harmony, Symmetry, and Resonance on LSD.


Featured image credit: Michael Aaron Coleman