12+ Reasons to Donate to ClusterFree

Why cluster headache mitigation should become your #1 effective giving priority this Season: impactful, novel, very alive, and with plausible fast results!

By Andrés Gómez Emilsson, ClusterFree Co-Founder & Member of Advisory Board

TL;DR: To motivate action and feel genuine internal alignment around a decision, sometimes we need to see it from many different angles. Even when a single reason should be enough, we need to motivate our entire internal coalition of subagents! Hence, all of these reasons to support ClusterFree in its mission:

Summary of the 12+ Reasons to Support This Cause

  1. Watch real people rapidly improveVideo testimonials of torture stopping in minutes
  2. Logarithmic scale of impact – Helping someone with this condition is potentially one of the highest-leverage interventions anyone can do as a gift to someone’s life
  3. Insurance against illegible suffering – Building a world that takes invisible pain seriously, including your own in the future! (crossing fingers you never experience such things!)
  4. Proof-of-concept for valence-first cost-effectiveness – This illustrates the corner cases where QALYs/DALYs fail catastrophically
  5. Intellectual coalition – Scott Alexander, Peter Singer, Anders Sandberg, Robin Carhart-Harris, etc. have seen the evidence and are convinced this is real
  6. Schelling point for suffering reduction – Network effects for future high-impact work, attracting genuine talent to focus on deep suffering reduction is its own value proposition
  7. It’s a strike against medical paternalism – Informed consent for known therapies, even when not officially approved, when it comes to extreme suffering, should always be an option on the table
  8. Actually tractable – Success looks like a 3-5 year timeline with a clear theory of change
  9. Speed cashes out in suffering prevented – 70,000 people in extreme agony right now, every day of delay matters greatly
  10. Works as an accelerant for an existing movement – Adding coordination to grassroots momentum that’s already underway (giving the psychedelic renaissance wings!)
  11. Psychospiritual merit (if you believe in “karma”) – Buddhist texts specifically highlight headache relief, “immeasurable merit” in store for you and your loved ones if you decide to help with clean intentions
  12. Bodhisattva vision – Practice looking into darkness without flinching
  13. Bonus – I’ll stop talking about Cluster Headaches in Qualia Computing!: Fund it so I can get back to core QRI research

Introduction: Why Multiple Reasons Actually Matter

In principle, deciding where to donate should be straightforward: calculate expected value, fund the highest-impact opportunity, done. In practice, we’re coalitions of subagents with different reward architectures, time horizons, epistemics, and thresholds for action.

At a neurobiological level, motivation doesn’t work the way we pretend. It’s not about “willpower” or “being convinced by good arguments.” Different brain regions make “bids” to the basal ganglia, using dopamine as the currency. Whichever region makes the highest bid gets to determine the next action. Scott Alexander explains this in Toward A Bayesian Theory Of Willpower (2021). What we call “motivation”, within this framework, is just whichever subsystem’s bid is currently winning. Whether the details are right or not, I think this tracks how I see people behave.

If you want to trigger high-effort action, giving just one reason may not be enough. That only raises one bid. Layer multiple kinds of reasons (emotional, moral, social, self-interest, narrative, identity-based), and you multiply the bidders in your internal parliament. Scott uses stimulants as an example: they “increase dopamine in the frontal cortex… This makes… conscious processes telling you to (e.g.) do your homework… artificially… more convincing… so you do your homework.”

Look, I’m being straightforwardly manipulative here. Giving you twelve reasons instead of one is designed to activate more of your subagents. But it’s prosocially manipulative – to help you integrate a truth you might already intellectually accept but haven’t acted upon yet. The bullet point approach can be misused when it obfuscates (think laundry list of complaints when there’s really just one big issue), so let me be meta-transparent: I genuinely believe ClusterFree is extremely high-impact, and I’m deliberately structuring this to get past your action threshold. If any one or even several of these reasons feel less convincing to you, ignore them. The robust core case stands on its own.

There’s also the threshold problem. In Guyenet On Motivation (2018), Scott discusses how higher dopamine makes the brain more likely to initiate any behavior. When dopamine is low, even strong reasons may not overcome inertia. Increased dopamine “makes the basal ganglia more sensitive to incoming bids, lowering the threshold for activating movements.” Sometimes what’s needed isn’t better arguments but enough energetic activation to allow any reason at all to push action over the threshold. Which is why you should read this while high on LSD and/or Adderall fully rested and energized.

Naturally, this connects to annealing. At QRI, we think of belief updating as requiring an energetic process. It’s not enough to know something matters; you need metabolic resources to actually integrate that knowledge and reconfigure your behavior accordingly. The REBUS (RElaxed Beliefs Under pSychedelics) framework applies here: people intellectually understand that cluster headaches are astronomically bad, that preventing them is extraordinarily high-leverage, and that this is one of the most intense forms of suffering you can and should urgently address. Yet this knowledge may remain compartmentalized and inert, unable to meaningfully shape action, resembling other “ongoing moral catastrophes” by which future generations may judge our society.

What breaks through? Multiple simultaneous channels of evidence that together cross energy thresholds. Emotional resonance. Social proof. Narrative coherence. Personal connection. These aren’t redundant: they join together as a gestalt that pushes forward the energetic budget needed for actual system-wide updating.

So here are the twelve reasons to support ClusterFree. Not because you need all twelve to “get it” intellectually, but because different reasons will activate different coalitions in your brain.

And if you’re not in a position to donate but still want to help – please keep reading. There are many high-impact ways to contribute at the end!


1. You Can Actually See People Rapidly Improving

Most charity is abstract. You send money into a statistical void and trust the meta-analyses.

With ClusterFree, you can watch video testimonials of actual people describing how psilocybin or DMT stopped “the worst pain imaginable” in minutes. The person who was screaming, punching walls, and contemplating suicide is suddenly calm, coherent, and alive again.

Watching someone’s face change like that hits you differently than reading a cost-effectiveness analysis. Your brain gets direct evidence of the state change. You see the suffering stop.

And strategically, patient testimonials are how this actually works. Raw video testimonials of “this stopped my torture” create demand that no institutional gatekeeping can fully suppress. People are already using this in advocacy. We’re just collecting the stories systematically and making them impossible to ignore. One major medical center sees enough of these, runs a supervised protocol, publishes clean results, and every other institution’s liability calculation flips.


2. On the Logarithmic Scale of Helping Another Human, This Is Unfathomably High

Preventing cluster headaches for life is plausibly one of the single largest “good deeds” a human can do for another human being. Yes, this is grandiose. But if something big IS true and you know it, pretending it’s not to avoid looking grandiose is fake humility that damages the cause.

Cluster headaches are called “suicide headaches” because the pain is so extreme that people actively contemplate ending their lives during attacks. Patients report “drilling through my eye socket,” “being stabbed in the brain,” “pain so bad I can’t think, can’t speak, can’t do anything but scream.”

Here’s a rough intuitive sketch of what the logarithmic scale of helping another person might look like (this isn’t rigorous math – it’s an illustration of what’s likely the case, directionally right[1]):

  • 10^0: holding a door open
  • 10^1: gifting a pen
  • 10^2: introducing them to someone useful
  • 10^3: helping them move places
  • 10^4: catching a major work or family mistake before it ruins their week
  • 10^5: teaching them a compounding skill (meditation, programming, emotional regulation)
  • 10^6: funding their higher education, changing their entire socioeconomic trajectory
  • 10^7: helping them escape a pathological family system
  • 10^8: preventing them from falling into a cult, deep addiction, or abusive relationship
  • 10^9: curing a chronic condition like treatment-resistant generalized anxiety disorder (GAD)
  • 10^10: saving their life while preserving psychological integrity
  • 10^11: giving them a permanent upward shift in baseline wellbeing and quality of consciousness, such as advanced contemplative practice can do over the course of decades
  • 10^12: preventing cluster headaches for life

Why 10^12? A single cluster headache attack is plausibly in the 10^9 to 10^11 range of negative valence – orders of magnitude worse than migraine, worse than childbirth, worse than even torture. A typical patient experiences thousands of these across their lifetime. The multiplication is straightforward.

We’ve done empirical work quantifying cluster headache intensity using patient self-reports, cross-condition comparisons, suicide attempt rates, and other methods. Full details in our EA Forum posts (Quantifying the Global Burden of Extreme Pain from Cluster Headaches, Logarithmic Scales of Pleasure and Pain) and our Nature: HSSC paper.

The theory of change for the open letters on ClusterFree is straightforward:

Patient testimonials – Raw evidence that DMT/psilocybin (even at subhallucinogenic doses) works for a large fraction of sufferers, spreading organically through desperate communities. This is already happening underground.

Reputation-Amplified Legitimization – Get enough credible voices (clinicians, researchers, policy experts) publicly acknowledging both the crisis and the evidence. We already have 800+ signatures, many from extremely prestigious people. This shifts what’s discussable. Journalists cover it differently. Clinicians stop whispering with fear of judgment and start preparing, even if quietly at first (I’m already seeing signs of this in some groups).

Clinical cascade – One major medical center runs a supervised protocol, publishes clean results, and every other institution’s liability math inverts. You don’t need consensus. You need one proof point, and the dominoes fall.


3. It’s Insurance Against Your Own Extreme Suffering Being Dismissed

Cluster headaches are invisible. No blood, no broken bones, nothing on medical imaging. Just someone screaming, rocking, punching walls while doctors tell them to “try reducing stress”, “have you considered yoga?”, or “maybe try an Ibuprofen?”.

This is what illegible suffering looks like. People don’t believe you. Institutions can’t help you. You’re trapped in a cage of agony that no one else can see.

Supporting work on illegible suffering means supporting the principle that intense subjective experience matters even when it can’t be measured easily. By supporting ClusterFree, you’re building the world where, if you ever wind up in incomprehensible pain (chronic illness, treatment-resistant conditions, novel syndromes medicine doesn’t understand yet, a hard-to-communicate and hard-to-alleviate pocket of deep biopsychosocial suffering), people will actually take it seriously. Where “I am in agony, and this helps” is treated as highly important data, the existence is safer and more dignified.

Medical, institutional, and social gatekeeping kills people. It traps them in years of unnecessary suffering because the safe and affordable tools that work aren’t “approved” yet. By supporting the patient-driven, evidence-based access to what actually helps, you’re contributing to practical moral betterment and making the world safer for everyone who might need it. Including you.


4. It’s a Proof-of-Concept for Valence-First Cost-Effectiveness

Most effective altruism uses QALYs (Quality-Adjusted Life Years) or DALYs (Disability-Adjusted Life Years) to evaluate interventions. These metrics have a major limitation: they systematically underweight extreme suffering. A QALY-based analysis of cluster headaches captures some utility loss but misses orders of magnitude of suffering because attacks are brief and non-lethal – even though they’re torture-level and recurring. The frequency distribution is also extremely skewed (some sufferers have 10+ attacks daily), which standard health economics frameworks struggle to properly account for.

ClusterFree evaluates interventions based on how bad things actually feel and what their actual prevalence is – not through the lens of reduced life expectancy or economic burden: “How much suffering are we preventing when measured by its actual intensity?”.

We’ve quantified cluster headache intensity and prevalence using patient self-reports, cross-condition comparisons, suicide attempt rates, and other complementary empirical methods. The result is clear: cluster headaches score astronomically high. This is why preventing them matters so much more than conventional metrics would suggest.

If you want a future where we optimize for the real reduction of suffering instead of metrics that structurally and systematically ignore its most intense forms, ClusterFree is the seed. We’re showing how you can make rigorous, evidence-based decisions by taking the actual experience seriously. This serves as a template for charity evaluation and ethical triage (not necessarily to replace current Effective Altruism methods, but to add a _critical_ missing evaluation angle to the ensemble model for how to help most effectively). 


5. You’ll Be in the Company of Intellectual Giants

Scott Alexander supports this. Anders Sandberg supports this. Peter Singer supports this. These are thought leaders with decades of track records in rigorous, scout-mindset thinking about doing good. They don’t endorse lightly. They’ve looked at the testimonials, the statistics and trends, the theory of change, and said: this is real.

If you trust their epistemics even a little, their endorsement is strong Bayesian evidence. These aren’t people chasing trends or optimizing for social approval.

And beyond the rationalist/EA sphere? Robin Carhart-Harris supports this – one of the leading psychedelic neuroscientists in the world. Shamil Chandaria supports this – doing serious work on meditation, predictive processing, and contemplative neuroscience. Christopher H. Gottschalk supports this – a neurologist who actually treats cluster headache patients and knows firsthand how devastating they are.

EA thinkers, psychedelic researchers, clinical neurologists, contemplative scientists – they’re all saying the same thing. That doesn’t happen often.

You get to join this coalition early. While it’s still underrecognized. While it requires actually engaging with the arguments instead of following the consensus. While supporting it means skin in the game.

Supporting ClusterFree now signals good taste (you can spot high-impact opportunities before they’re obvious), high reasoning capacity (you can evaluate complex arguments across disciplines), genuine compassion (you care about actual suffering, not just legible causes), and epistemic independence (you can disagree with the consensus when the evidence demands it).

When this becomes mainstream (and it will), you were there first.


6. It’s Creating a Schelling Point for Serious Suffering-Reduction Work

ClusterFree is reducing the coordination costs and bringing together people who can spot neglected pools of immense value early on.

Researchers who care about phenomenological intensity. Clinicians frustrated with institutional gatekeeping who want evidence-based psychedelic medicine. Policymakers who understand regulatory strategy. Patients with direct experience who want to help others. All working on the same thing with a clear theory of change.

Many causes tend to be either too vague (“reduce suffering”) or too narrow (“fund this one study”). ClusterFree hits the sweet spot – it is specific enough to be actionable, broad enough to matter at scale, and legible enough to attract serious supporters.

The network effects compound. When the next high-leverage suffering reduction project comes along, there’s already a group of competent people who know how to execute. The people showing up now will co-build what comes next. Rather than funding one project, you’re seeding a network that keeps generating high-impact work.


7. It’s a Strike Against Paternalistic Control Over Suffering Relief

Right now, people with cluster headaches are told they cannot officially access psilocybin or DMT – the interventions that consistently, rapidly, and reliably work for a large fraction of sufferers – because the institutions have decided they’re not allowed to make that informed choice. Even when they’re screaming in agony. Even when they’re suicidal. Even when nothing else helps.

Medical paternalism is at its most cruel when patients hear: “We know you’re suffering, but you can’t have the effective, affordable, and safe-to-manage thing that stops your agony, because we haven’t finished the proper studies yet, and/or because of the system’s inertia.” Never mind that converging evidence shows it works. Never mind that patients are already using it skilfully and reporting dramatic relief. Never mind that the risk profile is more than worth it given the suffering prevented.

ClusterFree, with your support, is building the legal, scientific, and social infrastructure to challenge that amoral status quo. We pave the way for informed consent, supervised access, and letting people make rational decisions about their own unbearable pain.

If you value bodily autonomy, participatory medicine, and the right to pursue relief from extreme suffering, this is the fight. And it’s winnable thanks to multiple predictors of success. 


8. This Is Actually Tractable

Most extreme suffering feels impossibly hard to address. Oftentimes, contemplating extreme suffering causes a sense of helplessness. It’s too big, too entrenched, and too complex. You can care deeply and still feel like there is nothing you can meaningfully do about it.

Cluster headaches are different. We have video testimonials. We have 800+ signatures from people with institutional power. We have a clear mechanism – psilocybin/DMT abort attacks rapidly and safely. We have willing clinicians ready to run supervised protocols. We have patient demand already creating the underground adoption.

The main barrier is coordination and legitimacy-building. That’s where ClusterFree steps in: we close the gap between common knowledge and the rollout of systemic solutions. 

And we’re going beyond mere advocacy. Bob Wold of ClusterBusters calls DMT a “breakthrough therapy” for its near-instant pain relief; we’re working to understand why it works, so we can foster next best steps. Our research includes exploring legal, non-hallucinogenic (or only mildly hallucinogenic) alternatives like 5-MeO-DALT, which one patient discovered in Shulgin’s TIHKAL and used to successfully treat 46 cluster headache patients. Developing targeted therapies based on understanding the mechanisms and testing new approaches translates into accessibility and effectiveness.

We (admittedly optimistically) believe this is doable within 3 to 5 years of focused and effective execution: build the coalition, get one major medical center to publish clean results, and watch the common knowledge cascade. Meanwhile, we’re already developing better treatments with maximally broad legal adoption.

Most things that matter this much take decades… or never even happen. This one is actually within reach.


9. Every Month of Delay Means Unnecessary Pits of Suffering

Right now, while you’re reading this, ~70,000 people are experiencing a cluster headache attack. More will start in the next few minutes. And more after that, like a global wave of agonizing pain.

Roughly 3 million people worldwide have cluster headaches in any given year. Many experience attacks daily or multiple times per week during the cluster periods. We estimate that globally, cluster headache patients spend approximately 70,670 person-years per year in pain, with about 8,570 person-years (about 3.1 million person-days) spent at extreme pain levels (≥9/10).

The math is brutal: with every month of delay, patients undergo millions of preventable torture-level attacks. While other cause areas and interventions may warrant dilemmas of donating now or later, the case of ClusterFree is urgently clear – donate now, and we will do our best at bringing unimaginable counterfactual relief to millions in 2026-2027. 

Our model is designed for speed – we are not waiting for perfect RCTs, commercial products, or stable institutional consensus. We are building the strategic legitimacy cascade that lets institutions act on what we already know.

The suffering is happening right now. The effective solution exists right now. We know how to connect the dots, and the only question is how fast we can do so.


10. ClusterFree Is Accelerating an Already Developing Movement

ClusterBusters has been doing heroic work for years, building community, sharing information, and giving people hope. The psychedelic renaissance has been shifting cultural and scientific attitudes. Various researchers and advocates have been pushing this forward through different channels.

ClusterFree adds a specific piece: demonstrating that this is a winnable fight right now.

We bring:

  • An explicit theory of change (testimonials lead to reputation-amplified legitimization, which leads to clinical cascade);
  • 800+ signatures from outstanding individuals, many with institutional power and cultural influence;
  • A straightforward narrative: “this is effective, safe, and urgent, and we can scale this legally” – and we’re not afraid to signal DMT as especially promising (due to its extremely fast pain relief profile when “vaped” at the onset of an attack);
  • Coordination infrastructure that connects patients, clinicians, researchers, and funders around a shared goal; and
  • A global but local-context-sensitive approach in both coverage and mindset: while ClusterBusters focuses on the U.S. and UK, we’re building parallel advocacy tracks across multiple jurisdictions (Canada, Europe, Latin America, etc.) to build the missing capacity.

This strategy acts synergistically with other approaches, de-risking them rather than obstructing them. When a major medical center decides to run a supervised protocol, they will do it in an environment where 800+ credible voices (as of December 13th 2025) have already confirmed that this is real, this matters, and the research must take place as soon as possible.

Our strategy is being developed and executed by uniquely talented individuals with a strong track record. Alfredo Parra leads the organization – he is exceptional at navigating the interface between institutions, has 7+ years of nonprofit management experience, and is provingly extremely conscientious and high-integrity (don’t take my word for it – look at all the work). The team and the community that seeded it concentrate people who simultaneously understand the importance of suffering reduction, psychedelic phenomenology, regulatory strategy, and movement building. They both care about the deep structure of consciousness and aren’t swayed by common narratives. This is a rare comparative advantage, and in our view, proves an excellent fit to push this cause forward.

The fruitful work has been happening already. Where we step in is providing leverage at a specific bottleneck: making the path to legitimacy visible and coordinated.


11. If You Take “Karma” Seriously, Look at What the Texts Say About Headache Relief

In the Bodhicaryāvatāra, Śāntideva teaches that “immeasurable merit” arises even from the simple thought: “Let me dispel the headaches of beings.” The tradition treats this literally. Not metaphorically. Relieving sharp, overwhelming pain generates outsized karmic effects because it interrupts some of the most intense forms of duḥkha in the human realm.

Why headaches specifically? Because they were considered the archetype of piercing, mind-breaking pain in the classical world. Cluster headaches exceed even that ancient benchmark. They represent some of the most unbearable moments a human mind can experience.

The logic of meritorious karmic logic is clear: if intention aligned with the relief of severe suffering produces merit that scales with the intensity of dukkha relieved, then work that prevents torture-level pain for thousands of people is not ordinary charity but a high-density, boutique, ultra-rare karmic investment.

For practitioners of the Bodhisattva path, karma constitutes a feedback loop shaping future clarity, opportunity, and awakening. Helping beings escape states of extreme pain is singled out across the Mahāyāna as one of the fastest ways to accumulate merit and purify obscurations.

If even contemplating the wish to relieve a single headache creates immeasurable merit, then actively supporting work that may end this class of suffering at scale plants karmic seeds that ripple across lifetimes.

Even if you hold a weak, naturalized version of karma (something like “intentions to help tend to produce good outcomes proportional to the good intended”), the efficiency here is absurdly high. Instead of helping someone have a slightly better day, you’re preventing thousands of hours of above-torture-level pain per person.

And what if you don’t believe in karma at all? The consequentialist case is still clear. You’re preventing, say, ~10^12 units of negative valence per person.


12. You Get the Bodhisattva-Tier Vision

Most people, when they look into the true darkness of suffering (the worst pain imaginable, sustained for hours, recurring for decades), recoil. They look away. They rationalize (“someone else will handle it”), they cope (“well, suffering is just part of life”), and freeze (“I can’t do anything about this anyway”).

Such reactions are understandable given the limits of our agency and the scope of the challenge. Luckily, there’s another response possible and available today:

You see it, and you roll up your sleeves. Where others flinch or cope, you take intentional action.

That capacity to clearly perceive the worst of what’s real and respond with competence, care, direction, and focus – rather than despair, avoidance, denial, or freezing – is a rare gem. It separates people who talk about compassion from people who enact it. The “Bodhisattva move” is: “I see the suffering. I will not turn away. I will do what needs to be done.”

Supporting ClusterFree strengthens that moral muscle. It’s a practice for the kind of person you may want to be: someone who can look into the darkest abyss and respond with pragmatism, not platitudes.


And a bonus reason for Qualia Computing readers…

So I Can Stop Talking About Cluster Headaches in Qualia Computing

Look, I very deeply care about this work, and this is why ClusterFree needs to claim its own space. QRI has a complementary mission to fulfill – studying and utilizing coupling kernels, topological approaches to the boundary problem, neural annealing frameworks, and the deep structure of valence.

The more ClusterFree is funded and self-sufficient, the more I can get back to the core theoretical work for which I’m best suited. Which, by the way, is exactly how we identify the next high-leverage suffering reduction opportunities!.

If you want me to shut up about cluster headaches and get back to talking for hours about beam-splitter holography and DMT phenomenology, the fastest way to make that happen is to generously fund ClusterFree.

You’re welcome.


What We’re Specifically Asking For

ClusterFree is currently a two-person operation: Alfredo leading the day-to-day execution (coalition building, clinical coordination, policy navigation, the 800+ signature campaign), and me providing strategic direction, research frameworks, writeups like this one, and QRI infrastructure. The initial donations will let us hire additional top talent to manage critical workstreams, so that we can:

  • Pursue parallel regulatory tracks in different jurisdictions;
  • Optimize our media presence by talking to journalists, podcasters, and medical journals;
  • Build global partnerships with patient organizations, headache centers, psychedelic advocacy groups, and retreat centers that treat this and related conditions;
  • Coordinate with medical centers willing to run supervised trials;
  • Create high-quality topical resources for patients in multiple languages, which are scarce and difficult to find; and
  • Pursue other high-impact value streams we’re ready to launch with additional capacity.

If significant funding is obtained, it will allow us to personally visit retreat centers and bring people with cluster headaches to suitable settings where they can experiment with these therapies, and where we can study them thanks to the QRI approaches to systematic phenomenology mapping, including EEG and biorhythms monitoring. This might turn out to be really important, possibly allowing us to determine what aspect of psilocybin/DMT relieves the pain. Our working assumption, based on many interviews with sufferers, is that DMT’s “body vibration” effect is key for its pain relief – if true, this is something we could significantly optimize by developing more targeted therapies.

While our network of volunteers is growing (see Slack below), having dedicated paid staff accelerates our efforts dramatically. The faster we move, the louder we say “no” to overlooked suffering.


Can’t Donate But Want to Help?

There are many high-impact ways to contribute beyond financial support:

  • Sign the open letter – Adding your name increases our legitimacy and helps shift the Overton window.
  • Share patient testimonials – If you have cluster headaches and have used psychedelics, your story can help build the evidence base. We believe that video testimonials from sufferers, in particular, are especially powerful. Recordings showing the moment itself where psilocybin/DMT relieves the suffering in real time might have the most emotional resonance overall.
  • Join our Slack – We list simple but high-impact volunteer tasks (translations, social media, research assistance, essay feedback, etc).
  • Connect us with key people – Do you know journalists, podcasters, clinicians, policy makers, or potential donors? Introductions are greatly appreciated!
  • Spread the word – Share this essay, talk about cluster headaches with the right mood, and become the relieving change you want to see and experience in the world.

Conclusion

With all these reasons in mind, ClusterFree satisfies the utilitarian, the virtue ethicist, the long-term strategist, the person who wants meaning, the person who values courage, the person who wants to accumulate spiritual merit, the person who wants to bring these therapies to the FDA approval status, the person who just wants to see real humans stop screaming in pain, and the one who embodies all these motivations simultaneously.

Donate to ClusterFree

Donate to QRI (the incubator organization that made this possible, and conducts more aligned efforts)

Sign the open letter

Our internal coalitions can agree that this matters, and we can actually do it. Thank you.


Acknowledgments: Many thanks to Marcin Kowrygo for his generous edits of the draft. Thanks to Chris Percy, Roberto Goizueta, Hunter Meyer, and, of course, Alfredo Parra for relevant discussions and suggestions for this write-up. Huge thanks to the ClustersBusters team for their incredible and ethically urgent work (and generosity with their time to help people in need, as well as accepting being interviewed in a pinch at Psychedelic Science 2025). Thanks to Jonathan Leighton (OPIS) for inspiration, aligned work, and fighting the good fight! Thanks to Jessica Khurana (and her team) for founding Eleusina Retreat – the world’s only retreat center focused on using psychedelics, legally, for treating extreme pain conditions. Thanks to Maggie Wassinge for her copious emotional support, love, and motivation to keep doing the real work, even when it feels hopeless at times (seriously, THANK YOU). And to the spirit of Anders Amelin (RIP), who is always with us, encouraging and motivating, giving us strength and intelligence. May he rest in peace, knowing we’re pursuing our ambitious suffering-reducing goals <3 And thanks to the entire QRI team, as well as the broader qualia community at large, for creating a container where these ideas can be freely explored with curiosity and without stigma. And finally, thanks to all of the donors of QRI and ClusterFree: we will do what we can to make you proud of supporting us. Metta!


[1] On the 10^12 estimate: This is admittedly a back-of-the-envelope calculation, but here’s the reasoning. A cluster headache patient might experience anywhere from 3,000 attacks (conservative, successful treatment) to 30,000+ attacks (severe chronic cases) over their lifetime. Using a conservative estimate of 3,000 attacks averaging ~60 minutes (3,600 seconds) each gives us ~10^7 seconds of extreme pain. Now for the intensity ladder. Holding a door open might prevent ~0.1 units of discomfort, using a pinprick as 1 unit. Kidney stones, already rated 10/10 on standard pain scales, are plausibly ~1,000× more intense than a pinprick (10^3). Each second of cluster headache pain appears to be ~10× worse than kidney stones (10^4 relative to our baseline). Multiply by 10^7 seconds, and we get 10^11 from pure hedonic intensity alone. Additionally, cluster headaches impose a constant inter-ictal burden (meaning, the suffering between attacks), including PTSD, anticipatory anxiety, and a profound sense of doom between attacks (see interview with Cluster Busters founders at 53:10-53:40). This could add a 2-5X multiplier, bringing us to ~10^12. For severe cases with 10× more attacks, the calculation easily reaches 10^13 or higher. The true value likely ranges between 10^7 (very mild cases with effective treatment) and 10^16 (severe chronic cases accounting for peak intensities and suffering between attacks). Even at the conservative end, preventing cluster headaches for life remains one of the highest-impact interventions accessible to individuals. Similar back-of-the-envelope calculations can be done to put in perspective each of the steps on the “logarithmic scale of help you can provide to someone”.


Scott Alexander in “Links For December 2024” (Dec 24 2025):

13: Alfredo Parra of Qualia Research Institute on cluster headaches. Cluster headaches are plausibly the most painful medical condition. If you ask a cluster patient to rate their pain, they’ll almost always say 10/10. Does that mean the headaches are twice as painful as a 5/10 condition? There are some philosophical reasons to expect pain to be logarithmic, so plausibly cluster headaches could be orders of magnitude more painful than the average condition. Once you internalize that possibility, it throws a wrench into normal QALY ratings and suggests that, even though cluster headaches are pretty rare, they might cause a substantial portion of the global burden of disease (or even a substantial portion of the suffering in the world). Some psychedelics, especially psilocybin and DMT, seem to treat cluster headaches very effectively, so the more you believe this reanalysis, the more interested you should be in figuring out how to turn these into an accessible therapy (see clusterbusters for more information on this aspect).

And more recently in “Open Thread 409” (Nov 24 2025):

2: Qualia Research Institute announces their spinoff effort ClusterFree. Cluster headaches (aka “suicide headaches”) are probably the most painful medical condition known to science, which makes them a natural priority for some utilitarians. They seem to be extremely treatable by psychedelics like psilocybin and DMT (including sub-hallucinogenic doses), so ClusterFree is working on getting governments to research this further and maybe get these drugs into the medical pipeline (cf. ketamine for depression). There’s an open letter here, and you can contact them here. The information for patients is at the bottom of this page.

Peter Singer in his recent piece “The Best Treatment for the Most Painful Medical Condition Is Illegal” (Dec 11 2025)

A recent article in Nature: Humanities and Social Science Communications found the funding provided in the United Kingdom for research on cluster headaches to be “orders of magnitude” less than that provided for multiple sclerosis, a condition that affects a similar number of people. The authors conclude that, given that we regard the provision of anesthesia for surgery to be essential, we should also recognize relief for extreme pain as essential. Finding ways to do so should warrant the highest funding priority.

A new initiative called Clusterfree has launched global open letters calling on governments to provide legal access to psychedelics for people with cluster headache. I have signed, and I hope that you will, too.

Announcing ClusterFree: A cluster headache advocacy and research initiative (and how you can help)

[xposted in EA Forum]

Today we’re announcing a new cluster headache advocacy and research initiative: ClusterFree

Learn more about how you (and anyone) can help.

Our mission

ClusterFree’s mission is to help cluster headache patients globally access safe, effective pain relief treatments as soon as possible through advocacy and research.

Cluster headache (also known as ‘suicide headache’) is considered the most painful condition known to mankind. We believe it is one of the largest sources of preventable extreme suffering in humans today. Every year, about 3 million adults (and an unknown number of minors) suffer from this debilitating condition.

And yet, even in the EU, only 47% of the cluster headache population had unrestricted access to standard treatments (primarily oxygen and triptans) in 2019. Despite affecting a similar number of people as multiple sclerosis, global investment into cluster headache is minuscule.

At the same time, countless patients have reported previously unattainable relief using certain psychedelics, even at low doses. For example, psilocybin, LSD and 5-MeO-DALT can effectively prevent attacks, and N,N-DMT can abort attacks within seconds and also have some preventative effects. However, these life-saving treatments are inaccessible to the vast majority of patients.

We want to tackle these problems by:

  • Publishing open letters demanding that governments, regulatory bodies, and medical associations worldwide take action immediately, with a focus on easing restrictions around psychedelic use.
  • Providing patient groups with high-quality resources and supporting their advocacy efforts.
  • Engaging with policymakers globally to advocate for better access to treatments.
  • Publishing research on cluster headache and supporting other researchers in the field.
  • Collaborating with entrepreneurs and philanthropists motivated to bring new, effective treatments to market.

About us

ClusterFree is a non-profit initiative incubated by the Qualia Research Institute.[1] It is led by Alfredo Parra, with Andrés Gómez Emilsson (President, QRI) as co-founder. Bob Wold (Director, Clusterbusters) and Jonathan Leighton (Executive Director, OPIS) are members of our Advisory Board.

We will be collaborating closely with Clusterbusters, the largest and most well-known cluster headache advocacy organization, led and run by patients. For about 25 years, they have been at the forefront of cluster headache advocacy, especially in the US and the UK. We are excited to bring more capacity and new approaches to tackle other jurisdictions, and to show that patients are not alone in this fight.

How you (and anyone) can help

As our first project, we are publishing one global open letter and 11 country-specific open letters:[2]

Anyone can sign the global open letter. Additionally, if you live in or come from one of the countries above, you can sign that letter as well. Signatories include Prof. Peter Singer, Scott Alexander, Dr. Christopher Gottschalk (Yale), David Pearce, and Dr. Daniel Ingram.

Please share the letters widely within your network![3]

If your organization wants to show its support for ClusterFree’s mission, we can list it as a partner on our website.

A few other ways to help include:

  • Donating or putting us in touch with potential donors. Donations are tax deductible in the US.
  • Volunteering for various tasks (many of which are very simple but high-impact).
  • Connecting us with journalists, podcasters, or influencers.
  • Offering any pro-bono services that could help the cause.
  • Giving us feedback on the website.
  • For patients: Sharing your testimonial (which we can feature here).

You can get in touch any time.

Room for funding

We have been making good progress on a shoestring budget during the past few months. Among others, we:

  • Started an official collaboration with Clusterbusters.
  • Gained the support of a member of a US state legislature.
  • Started conversations with CH advocates in multiple countries (most recently India[4], Denmark, and New Zealand).
  • Are engaging with entrepreneurs and philanthropists interested in bringing DMT to market.
  • Developed a preliminary idea for a new, legal abortive treatment that could be highly effective (potentially also for migraines).
  • Have started developing phenomenology-based, patient-centric surveys to test various hypothesis for the underlying mechanism of action that psychedelics exert on this condition.

We recently raised seed funding from a private donor to cover our core operations for the coming months. Additional funding would allow us to hire a second teammate to work alongside Alfredo at this early stage, particularly on outreach and communications. We could absorb an additional $50k–$150k immediately.

At this very early stage, we are still evaluating different paths to impact, and will likely test various strategies simultaneously to identify the most promising opportunities.

We believe ClusterFree is a great donation opportunity for people who care about relieving the most intense human suffering today. Cluster headaches represent a major health crisis even in developing countries, and we are far from having effective treatments widely available. Help us change that.

Donate

Additionally, you can consider donating to Clusterbusters or OPIS, who have been at the forefront of cluster headache advocacy and research for years.

Work with us

If you’d like to help us reduce the global burden of cluster headache pain (beyond volunteering), we’d love to hear from you. Simply fill out our expression of interest form.

Further information


  1. We are considering incorporating a charity in the UK. In the meantime, ClusterFree is fiscally sponsored by QRI.
  2. We are very grateful to the various volunteers from the EA community who contributed to the translations.
  3. Asking people individually to sign the letters works much better than asking in groups.
  4. Many thanks to Jacob Woessner’s volunteering work on this front.
  5. Website and brand design by Lombaert Studio.

[Many thanks to Alfredo Parra for this writuep]

QRI Presents: Reverse Engineering DMT Phenomenology with Non-Linear Optics

This is more than a presentation. It’s an invitation to join the frontier of consciousness research 🙂

Spatiotemporal Coordinates: Thursday, November 20 – 4:00 PM – 10:00 PM PST – Frontier Tower (San Francisco, California)

Hello Qualia Community!

After a year of heads-down development (with glimpses shared on podcasts including Theories of Everything with Curt Jaimungal #1  #2) QRI is ready to reveal the full scope of our work mapping the state-space of consciousness, modeling phenomenology, and identifying the computational properties of consciousness. 

What We’ve Recently Accomplished In This Area:

​In 2023, QRI’s High Energy Awareness Research Team conducted two legal psychedelic retreats exploring mushroomsayahuasca and 5-MeO-DMT, by bringing together an interdisciplinary coalition ​of meditators, psychonauts, physicists, and mathematicians and working as a Think Tank for weeks at a time (see heart.qri.org).

Systematic DMT phenomenology reveals repeatable phase transitions and geometric transformations, including hyperbolic curvature, symmetrification effects, and computational properties that demand explanation. The QRI period 2024-2025 has been about developing conceptual frameworks and computational models to make sense of these patterns, and then putting them to empirical test. We’ve discovered how coupling kernels (the rules of interaction between oscillating systems) can simultaneously shape both neural activity and the topological structure of physical fields, providing a potential causal chain from neurochemistry to the structure of conscious experience. It’s a conceptual framework where the pieces of the puzzle finally seem to fit together: how psychedelics modify coupling dynamics at the neural level, how these changes cascade through neural architectures to modulate field topology, and how this field structure feeds back into neural activity, avoiding the trap of epiphenomenalism while grounding phenomenology in processes with computationally meaningful properties.

What’s Next:

​This event is divided into two parts.

  • We’ll present the core outputs of our research from the past year: methods, participants, results, and the theoretical frameworks we’ve developed. You’ll see interactive demonstrations and simulations that bring these concepts to life.​
    • 4:00 PM – Doors open, mingling with snacks and soft drinks​
    • 5:00-5:40 – Introductions and interactive demonstrations​
    • 5:40-6:40 – The Big Reveal: QRI’s psychedelic research over the last two years, including HEART retreat resultsinteractive simulations, and our theoretical breakthroughs
  • We’ll chart our path forward: In Q2 2026, we’re planning a legal psychedelic retreat where mathematicians, physicists, meditators, and visual artists will collaborate to test whether non-linear optics plays a role in psychedelic phenomenology (especially DMT). This generative framework, which we take seriously and can rigorously test with proper funding, will combine physics simulations, psychophysics studies, and rigorous phenomenological mapping to reverse engineer the medium of computation of consciousness itself.​
    • 7:00-8:00 – The Next Chapter: 2026 retreat plans, mathematical modeling of consciousness, and testing our generative frameworks​
    • 8:00-9:00 – Q&A and group discussions​
    • 9:00-10:00 – Mingling and winding down

We anticipate that once we recognize consciousness’s computational role, we will move from cognitive science to consciousness engineering: systematically exploring the state-space of possible experiences and recruiting new qualia varieties to enhance our (conscious) cognitive capabilities.

Presenters at this event:

Andrés Gómez-Emilsson: As QRI’s President and Director of Research, his work at QRI ranges from algorithm design, to psychedelic theory, to neurotechnology development, to mapping and studying the computational properties of consciousness. Andrés blogs at qualiacomputing.com.

Cube Flipper: With a deep understanding of wave dynamics and visual perception, Cube is dedicated to uncovering the intricacies of visual phenomena. In addition to their research at QRI, they also share their insights and findings on their personal blog smoothbrains.net.

What We’re Fundraising For:

To continue this groundbreaking work, we’re seeking support for:

  • Core operations: Salaries to keep QRI’s team intact for another year (and hopefully many more)​
  • Two major retreats: The 2026 DMT phenomenology retreat and a 5-MeO-DMT awakening retreat
  • Research outputs: Publishing papers and studies, including upcoming pain quantification research (currently private, soon to be released)​
  • Technology development: Bringing crowdsourced phenomenology visualization tools to a fully functional state to crowd-source the mapping of the state-space of consciousness​ (first batch to be released on November 20th)
  • Additional initiatives: Cluster Headache relief research and research in digital sentience (we will announce two QRI-incubated initiatives that further these two causes)

Whether you’re a researcher, artist, meditator, potential funder, or simply fascinated by the nature of consciousness, this event offers a rare opportunity to see cutting-edge phenomenological research as it unfolds. We’re also gauging interest for the 2026 retreat: if you have relevant expertise (mathematics, physics, meditation, visual arts), funding capacity, or alignment with this vision of consciousness research, we’d love to connect.

If you’re unable to make it but would still like to contribute to our research efforts, you can donate at qri.org/donate or with crypto on our Endaoment page.

RSVP to the Event

Technical Appendix: Recent Developments


​This year’s QRI-associated essays reveal multiple converging lines of investigation:

Non-Linear Optics Framework: A generative framework exploring how the brain might render world simulations using optical elements. Key metaphors include Laser Chess (where local classical moves set constraints, then holistic standing wave patterns emerge) and Cel Animation (describing how the world simulation is constructed with independent layers controlled by different modules that overlap and interact in a shared perceptual workspace). This includes work on beamsplitter holography to explain Indra’s Net phenomenology.

Fractional Fourier TransformRecent work explores how the brain may *utilize* the fractional Fourier transform, which is a generalization that smoothly interpolates between spatial and frequency domains. This could explain characteristic ringing artifacts in psychedelic visual fields and provide a biologically plausible mechanism for massively parallel pattern recognition.

Coupling Kernels and CDNS and Field Topology: A breakthrough framework showing how systems of coupled oscillators can both tune into resonant modes and control the topological structure of fields. This provides a direct causal chain from molecular interactions (neurotransmitters, psychedelics) to the structure of conscious experience. The coupling kernel acts as a “field-shaping operator”, the same mathematical object simultaneously modulates neural dynamics and field structure, explaining how psychedelics produce such radically different yet structurally consistent effects across participants and experiences. We hypothesize that DMT effectively implements a Mexican-hat coupling profile (strong negative coupling at short distances, positive at medium distances) creating competing clusters of coherence, while 5-MeO-DMT drives systems toward global phase synchronization. This connects to the Consonance-Dissonance-Noise Signature (CDNS) approach, which describes valence in terms of spectral properties such as consonance tracking positive valence, dissonance negative valence, and noise neutral valence. We we will make the case for why this proof-of-concept demonstrations are compelling and point toward testable predictions.

Ongoing Foundational Work: QRI continues to develop frameworks including the CDNS approach, the Topological Solution to the Boundary Problem (explaining how unified experiences emerge with precise boundaries), liquid crystal dynamics as phenomenologically significant, and logarithmic scales of pleasure and pain for rigorous quantification of experiential quality.

Catch up on the latest:

Binding, Minds & the Platonic Realm: Michael Levin, Andres Gomez Emilsson & Elan Barenholtz

How Networks Vibrate: From Oscillators to Eigenmodes

A Salon on Consciousness, Holograms, and Digital Psychedelics

Different Types of Artificial Minds: Digital, Analogue, and Hybrid

The Future of Consciousness: Consciousness and What It Means to Continue to Be

DMT for Cluster Headaches: Aborting and Preventing Extreme Pain with Tryptamines and Other Methods

Learn more:

Indra’s Net via Nonlinear Optics: DMT Phenomenology as Evidence for Beamsplitter Holography and Recursive Harmonic Compression

[Epistemic Status: Speculating on a key implementation detail within the paradigm of the Brain as a Non-Linear Optical Computer (BaaNLOC) – specifically, how the optical function of beam splitting could be used to compose the contents of a conscious simulation scene with principles of cel animation and holography. In particular, this may explain both how local phenomenal binding is implemented as well as the uncanny sense of being a multitude that are common on DMT-induced states of consciousness; featured image source]

Alternative Title: One Screen, Many Contributors: Explaining the One + Many nature of Experience with Non-Linear Optical Circuits

Background Readings – and key takeaways of each:

  • The Constructive Aspect of Visual Perception (by Steven Lehar): We learn that vision is a constructive process that uses bottom-up and top-down resonance as its generator. Of special note: a gestalt (when features become “more than the sum of their parts”) has spectral properties: it resonates in a specific way as a combination of frequencies and can click with, interface with, and even drag other gestalts. Waves inside gestalts collide with each other in a way that conveniently (and efficiently) abstracts its symmetries (e.g. how the “reverse grassfire algorithm” can be used to abstract the symmetries of shapes).
  • The Brain as a Non-Linear Optical Computer: Reflections on a 2-Week Jhana Meditation Retreat: Where I introduce the overall picture of BaaNLOC based on phenomenological observations I gathered at a Jhana retreat. The core idea is that the world simulation is rendered using optical elements (cf. Ising Machines: Non-Von Neumann Computing with Non-linear Optics). I hypothesized that there is a trade-off between how much we can experience sensations in a localized way vs. experiencing frequency-domain information. Jhana absorption is akin to pushing all of the information to the frequency domain: you’re a vibration rather than a location. We can hypothesize that the sense of simultaneity and non-locality comes from us being a standing wave pattern trapped in Total Internal Reflection (TIR) in the brain. The quality of experience, especially pertaining to each of the Jhanas, can be described in terms of an optical circuit that modulate the consonance, dissonance, and noise signature of gestalts, each of which is an optical “soliton” within the larger TIR pocket that delimits a moment of experience. Jhana meditation involves, among other things, interacting with gestalts in such a way that you harmonize them, and eventually build up to a level of coherence that allows the entire world simulation to achieve (one of several types of) global coherence.
  • The Electrostatic Brain: How a Web of Neurons Generates the World-Simulation that is You (by Fakhri, Percy, Gómez-Emilsson): “We propose that objects in your world simulation are made of patches in the neuronal lattice with distinct electrostatic parameters. The interaction of light with matter is governed by the material’s electrostatic parameters permittivity and permeability. Light propagates undisturbed through a uniform medium but reflects and refracts when these properties vary spatially, which is the principle behind how lenses manipulate light.” In other words, a theory for how “phenomenal objects” (and gestalts more broadly) acquire their solidity and individuation at the implementation level. Waves inside each gestalt behave differently than “outside” (but still within the world simulation) of them, due to literal electrical properties modulating the speed of wave propagation.
  • DMT and Hyperbolic Geometry: The core ideas to import deal with how DMT hallucinations can be explained in terms of a field of experience with an energy function: the simultaneous maximization of how “recognizable” and how “symmetrical” (both being “energy sinks”) a gestalt is. DMT energizes the world simulation, and the hallucinations we experience are downstream of the system trying to get rid of this excess energy. A psychedelic trip, therefore, is explained in terms of thermodynamics and as an annealing process that may, along the way, favor hyperbolic (and non-Euclidean, broadly) geometry. The world becoming a kind of kale surface (cf. “worldsheet“) is the result of the system “stitching together” an excess number of gestalts (that fail to dissipate quickly; cf. tracer effects). The gestalts are all trying to predict each other in a process of energy minimization that may do some useful compute along the way if we figure out how to harness it properly (cf. Cub Flipper’s recent ideas on the matter).
  • From Neural Activity to Field Computing: The key takeaway here is that we can modulate the topology of a field by parametrizing a network of coupled oscillators in such a way that you can “tune into” the resonant modes of the system and in turn interact with the field in a coherent way. If the field responds to the oscillators in a physical way (e.g. interpreting the oscillators as electrical in nature, and the field as the shape of the magnetic field, as one of many possible examples) attractors of the system of coupled oscillators may in turn instantiate specific and predictable topological structures in the field. The way this is relevant to the current post is that we see how e.g. electric oscillations (in gestalts) can create genuine boundaries in a field and allow entire regions to “behave as one” in turn.
  • Cel Animation as a Key Metaphor to Model DMT Hallucinations: This may be the most important background read – it outlines how both Laser Chess and Cel Animations can be used as system metaphors for how a wave-like non-local experience can interface (and be part of) a system with “classical” local parts. In the case of Laser Chess, we have a game where there is a local “classical” step (moving a piece) and then a non-local “holistic” state (shining the laser and seeing what standing wave pattern emerges as a result). The brain’s “slow” neural activity might be “placing” the classical optical elements as constraints at millisecond-speed, for then a “global” and “near instantaneous” interference pattern that solves the path integral of all possible trajectories within the pocket to take over as a global ultra-parallel medium of compute. In turn, Cel Animation (the way cartoons used to be made; transparent sheets that depict what is changing and leave everything else intact) can be used as a metaphor to describe how “awareness wraps around and moves around” in a field of gestalts. Our world simulation is akin to a projector that shines on a 3D diorama populated with holograms. The experience is the emergent light-field that stabilizes when light is shined on this diorama. Typically our diorama has a clear center, but depending on the kind, alignment, vibration, and symmetries of the gestalts present, more than one, or even no, “phenomenal center” might emerge: the light does not need to converge at a point, even if it usually does.
  • The Emergence of Self-Awareness: Conscious Holography as an Evolved Hardware Accelerator: Finally, this recent video explains how dimensionality reduction implemented at a physical level (with e.g. holograms a quintessential example) could be associated with moments of experience via a precise computational role of consciousness. Namely, we’re conscious because dimensionality reduction in holograms feels like something, and evolution found really good use for this physical process. That is, coordinating information in sensory fields of different dimensionalities in order to construct a coherent internal state that efficiently and accurately encodes both information types. This is reasonable because holographic compressions, at a physical implementation level, are a kind of distributed spatial knowledge that uses path integrals and superposition to encode large amounts of information. We could make the case that at the point of dimensionality reduction is when “reality can meet itself” by collapse in on itself.

Putting it all together: we have a model of moments of experience as a standing wave pattern inside a non-linear optical system. It is conceptually elegant, but still widely unspecified. We have noted how this conceptual framework would solve many philosophical problems while articulating the nature of otherwise extremely puzzling phenomenology (e.g. DMT breakthroughs). What follows is further speculation, specifically on how beam splitters could play a role in this framework. In particular, I’m going to describe and then try to explain the phenomenology of DMT’s autonomous entities as well as Indra’s Net (at the extreme) and then explain how a non-linear optical circuit with the right characteristics could give rise to these corner cases. In fact, as we will see, it makes sense to think of every experience as a kind of Indra’s Net but with significant opaque components. More on this later.

Context

I recently had the chance to talk to Michael Levin and Elan Barenholtz (thanks to Ekkolapto at University of Toronto!) on the topic of phenomenal binding and the Platonic Realm (hear also the conversation I had with Levin last year):

I recommend listening to the whole conversation, but I figured I’d share what I presented at the beginning to establish some context for further discussions. The talk was an interesting challenge for me because I was given exactly 5 minutes to present a case at the beginning of the panel. In general, I love to be challenged to deliver a specific insight or argument on a time limit. Although a fun exercise, I also realize that there is quite a bit of background needed to really get what I’m talking about. So this post will go over both the content of my presentation as well as its further implications. There will be a lot more QRI content on the topic of non-linear optical circuits in relation to consciousness coming in the future.

What Needs to be Explained

Two key phenomenological realities need to be explained. No matter how weird and absurd they may sound (they do happen, as a phenomenon), we need to take them seriously if our theory of consciousness is any good. The key idea we will circle back to is that we can explain this exotic phenomenology using non-linear optics as a substrate (at least conceptually). So, what is it that we ought to explain?

First, is the sense of autonomous entities while on DMT. While 5-MeO-DMT tends to generate a sense of global coherence that hints at Open Individualism, DMT instead tends to feel as if you’re being thrown into a deep ecosystem of rogue mindforms. More so, it is often reported that these entities not only feel like they are _not you_ but they also feel controlled by a variety of different agencies with disparate goals. It is also not the case that these agencies are in agreement about how to interact with you, as oftentimes fierce competition for attention and other cognitive or energetic resources ensues. It is for this reason we like to say DMT pushes you to a “competing clusters of coherence” attractor. More so, each of these clusters seems to have its own agenda and objective function. It often takes quite a bit of negotiating between the “parts” of the organism can “pull together” in one direction during the otherwise fragmented state of DMT intoxication.

And if that wasn’t enough of a mystery, the second is an even stranger but certainly no less real phenomenon: Indra’s Net. This is the feeling and felt sense that “everything reflects everything else”. Many people use to term to refer to an implicit quality of reality: interdependence. But when I use the term in this context, I’m pointing to a very real, very vivid, and very computationally non-trivial state of consciousness. It is _true_ that the state gives you the feeling that it has a lesson, message, implicit insight, etc. to deliver, and that it is that we’re all connected at a deep fractal level somehow, but leaving aside this impression, the immediate phenomenology of Indra’s Net is really something worth exploring and explaining in its own right.

I believe that Indra’s Net is a window into how consciousness works at a fundamental level, and in this essay you will see how we might be able to explain it in terms of non-linear optical circuits. But the deeper insight (note: don’t take a twig from the Dharma Tree, says Rob Burbea, instead go for the big flowers, the big fruits, the jewels of the path) is that perhaps “everything reflects everything else” is not a strange corner case you have to work to arrive at. But on the contrary, the sense that each part of experience has a clear identity, location, and boundary relative to every other part of experience, is itself the strange corner case – you have to twist and torque Indra’s Net just right so that its projection _looks_ like a normal everyday life type of experience. By default, consciousness is profoundly interconnected in overt and explicit ways. If so, a lot of the energy the brain is spending is on keeping the illusion that non-Indra’s Net states are the default somehow.

Another problem is that Indra’s Net sounds so outlandish and incredible that it is easy to dismiss as “recollection or confabulation after the fact”. The epistemological poverty of our predicament is further exacerbated by the fact that people tend to confuse semantic content and phenomenal character, in turn delivering fantastically confused and knotted trip reports.

So, let’s cut to the chase, what is so special about Indra’s Net and how does it actually manifest? Here is the essence of it: any gestalt on your visual/tactile field (which can be synesthetic, and typically is) can be an expression of the whole experience after a certain kind of transformation or information processing pipeline. Let me elaborate. In the classic case where Indra’s Net is expressed as a web of water droplets, then what you will see is that the content of every reflection (the light emitted by each droplet) is itself the whole scene, but transformed. Indeed, it is _what the scene looks like_ from that point of view (more or less). In turn, this is happening to every one of the elements on the scene. Each element is itself expressing what the rest of the scene looks like from its point of view. Each element is taking the whole scene, applying a transformation to it, and then expressing it back into the field for everyone else to see.

This is agnostic to the specific semantic content of the scene (though perhaps not entirely orthogonal, as content and shape are ultimately correlated). You could have an Indra’s Net experience of countless heavenly Jewels reflecting on each other in beautiful ways. Or you could have an experience of looking at hundreds of demon eyes, each one reflecting every other one. Or you could experience something much more computationally crazy, like a maze of mirrors and diffraction rays, where everything reflects everything else in highly non-trivial ways in maze paths you didn’t even know were mathematically possible. The point is that the mind seems to have this attractor state we can broadly point to with the term Indra’s Net, which corresponds to a state in which the geometric content of every gestalt reflects/and is connected to the content of every other gestalt and of the scene as a whole.

The question that naturally arises here is: why do we experience this on DMT? Seriously, why is this a common attractor state? Importantly, the feature that “the whole scene hangs together as an irreducible whole” in which “moving any part results in the whole state shifting and adjusting” is not, predicted, by current computational models of the mind (or is?). What would a theory that predicts Indra’s Net look like?

The core insight I want to share for the time being is that if we allow the whole experience to somehow “project onto itself” a transformed version of itself after underlying non-linear optical filters, then some of these features start to emerge for free.

At the limit, both DMT autonomous entities and Indra’s Net become sort of one and the same (!). In effect, it is not uncommon for the sense of the multiple entities to coalesce into a gigantic god-like hivemind that incorporates many gestalts at multiple scales and it makes it very clear that it is “one and all of them at the same time”. Indeed, one can perhaps re-interpret a lot of classic iconography (e.g. the hundreds of arms of the Hindu Gods) as perhaps a pictographic representation of the phenomenology of Indra’s Net. (See also how the improper stitching together of the holograms can result in misaligned Cronenberg-like DMT Shoggoths, too).

Both deep in a DMT experience, and also at high levels of meditative concentration (cf. hard Jhanas) Indra’s Net is really common. I want to emphasize how this is not a vague poetic metaphor. It is a concrete structure, where the phenomenological “screen” that makes up access consciousness (the part of your experience you can report on) is filled with clusters of agentic constructs (“entities”) that seem to be mutually inspecting and modifying each other. They behave like holographic cel animation layers, arranged with depth and dynamically interacting subcomponents that reflect the whole.

What we want is a conceptual framework that would make DMT autonomous entities as well as Indra’s Net a perfectly natural outcome. Indeed, perhaps even expected and obvious in retrospect. To do this, I will introduce a number of core ideas, all of them orbiting a central one: perhaps our “screen of consciousness” is being “beamed” to multiple semi-independent modules at the same time, each specialized in different aspects of information processing. In turn, these modules transform the beamed image, and then pull it together with the other post-processed images by the other modules, and projects it back onto the original screen. This is reminiscent of recurrent neural networks, non-linear optical networks, but above all, the core idea that intelligent dimensionality reduction is central to a well behaved mind. Let’s dive in!

One Screen, Many Contributors: Explaining the One + Many nature of Experience with Non-Linear Optical Circuits

Non-Linear Optical Circuitry at the core of the current iteration of BaaNLOC. The central screen beams copies of its content to semi-independent modules. Then each module applies learned non-linear optical transformations such as birefringence, diffraction, refraction, etc. The post-processed images are then pulled together, and after a final symmetry group transform (to know how to fit it onto the screen), are re-projected back onto the original screen. The experience that emerges is the steady state standing-wave pattern of Total Internal Reflection (TIR) trapped in the loop. Key idea is that the images projected from each module back to the main screen can interact with each other in a quasi-physical way there.

I start by portraying the overall geometry of a moment of experience, as illustrated by Steven Lehar:

Source: Cartoon Epistemology by Steven Lehar

Consider this “diorama-like shape” that contains phenomenal properties we can point to and discuss. It is deeply interconnected. An experience is not “just” a 2.5D screen of pixels, because something is actively integrating and interrelated all of those pixels under a shared “umbrella”: a point of view, or subject of experience. Whatever the true mathematical object is that corresponds to a moment of experience (cf. qualia formalism), it must be able to connect variables in ways that produce the specific patterns of binding we observe. The patterns of binding must somehow allow us to reconstruct the geometry of the experience as a whole. But the patterns of binding are complex. A cup is not merely a blue object – it has intricate structures like a handle and a floor and perhaps liquid content, features which are all put together into a coherent multi-level representation for us to interact with. Indeed, we have to ultimately provide a mathematical structure rich enough to model and account for all types of phenomenal binding. Worth mentioning is QRI’s long-standing idea of modeling experiences as graphs with nodes that represent qualia values and edges that represents the flow of attention. In this case, the nodes you attend to are salient due to reasons having to do with graph centrality (cf. PageRank). Why? Because e.g. PageRank tracks the probability of landing on a given node if you are doing a kind of random walk from node to node using the directed edge weights as probability of transitioning. The nodes with high PageRank are those for which “the flow of attention” leads to lakes where it pools and concentrates.

As explained already, we suspect that the psychedelic sense that “everything is connected to everything else” may not be an anomaly, but rather a feature of experience that is always present, only rarely made explicit. This kind of PageRank of attention is always ongoing. The geometry of experience seems to be a kind of stable equilibria that results from systems observing each other and creating representations with relative distances to each other. Naturally, experience is “self-reflective” for this reason (and not only due to introspection!). But Indra’s Net is a deeper kind of structure that is still way more interconnected than e.g. PageRank would suggest. We need something new:

The core idea is that the non-linear optical circuit diagram above might capture some of the more exotic and intricate aspects of phenomenology (as mentioned: autonomous entities and Indra’s Net). The sketch you see at the start of this section (“One Screen, Many Contributors: Explaining the One + Many nature of Experience with Non-Linear Optical Circuits”), aims to capture key structural insights for the generation of moments of experience, which beam splitters, birefringence, and image-teleporting TV stones (cf. “How does Television Stone Work?“; Ulexite) feeding a recursive optical loop. This loop allows many “sub-agents” to see the same field, alter it independently, and feed their changes back into the whole in real time. The equilibrium state of this process is what we experience as a moment of consciousness.

In the recorded discussion, Michael Levin offered an elegant metaphor for how self-organizing systems can “pull” you toward them, where constraints in the medium act like attractors and make parts of the problem solve themselves once enough structure is in place. One of his example was a triangle: if the fittest shape for a given problem involves a certain triangle (e.g. a triangular alga needs to have three specific angles at its corners to succeed in certain navigation task), you evolve the first angle, then the second, and the third is automatically determined by the laws of geometry (a free gift from Euclidean geometry; or the geometry of the network of relationships between the parts, more broadly, when we talk about intrinsic geometry). This kind of regularity is an example case for how complex systems can bootstrap themselves, where knowing part of the whole lock in the rest: symmetry reduces degrees of freedom, and constraint propagation allows the global pattern to self-assemble without exhaustive search. In Levin’s framework and worldview, these “free lunches” live in pattern-space or morphogenesis space (as we’ll see), so that once your system points to the right place, the rest of the pattern ingresses “into the physical”.

Indra’s Net might be one of these patterns. The state of consciousness where everything _explicitly_ reflects everything else, from this point of view, does not have to be built in its entirety from the bottom up; once parts of it crystallize, and high-level symmetries are locked in place, the rest already knows how to relax into its attractor. It’s worth mentioning Levin also pointed out that in his work with Chris Fields he extends the logic of navigation in pattern-space, to “morphogenesis space”. That is, the configuration space in which cells navigate to build and repair anatomies. Applying least action laws (perhaps the true building blocks of reality? Or the true underlying laws of reality?) not to physical three-dimensional space (which may itself be emergent) but to the implicit geometries that shape biological growth and repair, may explain how an organism navigates its possible self-organization and converges on an energy minima that is very wholistic in nature.

In the toy model I presented, a non-linear optical circuit containing beam splitters, birefringence, and image-teleporting TV stones feeds a recursive loop that allows many “sub-agents” to see the same field, alter it independently, and feed their changes back into the whole. The equilibrium of this process corresponds to a moment of consciousness: it’s the topologically closed standing-wave pattern that emerges out of the non-linear optical circuit reaching a point of stability – and then what it is like to be it perhaps corresponding to “the superposition of all points of view” within it (see Cube Flipper’s recent efforts to describe this way of “reading off” an experience out of a physical system).

The energy function locally rewards gestalts that succeed at being explanatory, meaning they can anticipate, compress, and model the behavior of other gestalts. This generates an ecosystem in which gestalts compete and cooperate by predicting one another, and some develop the capacity to swallow the entire scene and then re-express it in transformed form. The medium where these interactions occur (the phenomenal screen) is not a passive display (common misconception) but an active site of computation, where interferences between gestalts are identified and workshopped. It also plays the role of being a “metric” or “gauge” for the other various gestalts. The screen gives gestalts a kind of “radar” so that by emitting waves they can find each other “in 3D”. From this perspective, experience involves lifting the content of the field into higher dimensions (internal states of the modules), applying transformations there, and then re-projecting it back as a coherent standing wave onto 3D (or 2.5D). In fact, several semi-independent modules doing this in parallel and then responding to each other’s transformations. The result is often deeply interdependent and “enmeshed”, irreducible-seeming, as the process transforms experiences recursively mid-flight and converges on gestalts that get along well with each other, are explanatory, and can predict sensory input.

Beam Splitters

Let’s try to imagine this more concretely. First, let’s talk about beam splitters. A beam splitter is typically a piece of glass or plastic that allows a certain percentage of the light through and reflects the rest. They’re one of the pieces in the game Khet 2.0 (a variant of Laser Chess), where the laser effectively splits in two and has more chances to do damage to the other’s Kind (or Pharaoh). This multiplies the number of beams, and at least in some arrangements, can lead to combinatorial explosions. Beam splitters, I suspect, are ubiquitous in our brain’s information processing pipeline. The ability to carbon-copy a gestalt so that you can work on it in multiple streams in parallel is extremely empowering, and no doubt a core step in any serious implementation of non-linear optical computation. Think about the phenomenology of shifting around the content of a working memory module. Doesn’t it feel like you’re copy/pasting information from one part of your field to another? Beam splitters are also, I reckon, a key optical component of our world simulation that allows for parallel processing streams to get unified into the coherent experience we mistake for a single “simple” witness.

Teleprompters allow you to have “split vision” so that you can look at the camera while you read your speech. (cf. DIY Teleprompter). They’re a kind of highly functional beam/image splitters.


In an effort to making the above more relatable, let’s talk about a really cool invention: the holographic broadcasting system. It doesn’t exist yet, but it could. It should, in fact. For aesthetic, social, and computational reasons,. What is this I’m talking about? Check this out:

The Holographic Broadcasting System

Imagine this: in front of you is a special table. A table that shows an image. There are hundreds of other tables like it and they are all connected to each other. When you place something on the table, it appears as a hologram in every other table like it. You can use this to play board games with people in other countries in real time, or for strategizing, delivering presentations, and even solving a maze as a team.

Here is the twist: the object that you place on the table can itself be an object that holds a transformed image of the table. Say, the object you place on the table is an iPad that shows what the table looks like from your point of view (e.g. your glasses have cameras that beam data to the iPad). You can even do projection mapping on the table and overlay a digitally transformed version of what it looks like on top of itself.

Projection mapping: you use a model of the 3D scene so that you can “paint it” with a projector that displays a video of the very scene it’s illuminating, after processing it with digital tools.

Each person with access to (a parallel version of) the table might specialize in a different kind of transformation: some specialize in adding edge detectors that highlight the corners and sharp angles of what’s in it. Others perhaps do color enhancement. Yet another one does shape rotation, where it overlays rotated images of the table (or a region thereof) on top of itself. The result is that the table is a live hologram that gets to be edited in real time by many different groups of people, each looking for something different, and capable of emphasizing different features of this collective work of art.

But here’s what makes this system truly extraordinary: each hologram carries its own unique spectral signature (remember how you can do analogue Fourier transforms in optical circuits!). From the point of view of the system, each gestalt/hologram is a kind of molecule with distinct “vibratory modes” that interact with other nearby gestalts that share such frequencies. When an edge detector sharpens a visual element, it doesn’t just change the shape, it also “stamps” a vibratory signature, so to speak, onto the hologram metadata for the system to work with. From the point of view of the system as a whole, may at first seem like a simple object carries rich spectral (i.e. frequency/vibration in addition to position) information. Whether holograms in the table “get along with each other” is a function of how they resonate together, as a group (with other gestalts), and as a whole (how the whole state can self-harmonize, or not, with the presence of such features). Collectively, the local and global vibrations define how the system “wants” to settle, and how each region interferes and interacts with neighboring holograms.

Importantly, I think this is happening all the time. What is different about high dose DMT or hard Jhanas with prominent Indra’s Net phenomenology is the extent to which individual gestalts express information about the whole experience. Consider the spectrum that goes from a completely dark and uninteresting room, to a room that is filled with parallel mirrors, beam splitters, diffraction gratings, polarizers, etc. What the room looks like doesn’t change very much as a function of lighting and head position in the first room. But in the second room, subtle changes in lighting can change the look and feel of the whole scene, as well as subtle changes in head positioning or even direction to which the eyes are pointed. In both cases the rooms are ultimately made of the same kind of “material” (atoms, physically speaking; qualia, subjectively speaking). But the second room has implicit connections and relationships that makes it highly sensitive to things like angle of lighting. The punch line, as it were, is that both physical systems are kinds of Indra’s Net, at least in a raw physical sense: every part of the dark room does indeed reflect every other part, it’s just that the information has been scrambled and largely lost. But just because the materials are not reflective or smooth doesn’t mean that on a deep physical level we don’t find a web of interdependent physical fields giving rise to the room as a whole as a “point of stability” of the system. This requires “everything reflecting everything else”. It’s just that many of these reflections aren’t very interesting or coordinated! Yet they are always there.

Likewise, even very boring and prosaic “contents of the visual field” (say, a banana, an orange… a stim toy) without any “trippiness”, I would argue, do implicitly contain the “everything reflects everything else” quality. When you see a banana contextualized by being next to an orange, the very _meaning_ of the banana changes. It becomes, in look and feel, a “banana next to an orange” rather than a “banana plain and simple”. More so, now that this contextual relationship has been established, we see the same is the case for the orange. And once more, with recursion, we find that the banana starts to look like a “banana that’s next to an orange, which is next to a banana” and so on. In principle this sounds redundant. But it is not. On DMT trips, this “transitivity of context” may in fact break down. So, for example, you might find yourself contextualizing the banana by an orange, but the orange might feel like it’s coming from a space that _is not_ contextualized by the banana. At least not directly. It’s often as if the various gestalts on DMT could exist in semi-independent geometric spaces that only with joint attention can actually interact with one another. Thus, the Indra’s Net quality of experience is in some sense much more robust in “normal everyday life” relative to the depths of an ayahuasca journey. And that is because under normal circumstances we do in fact have that our phenomenal objects properly contextualize each other in a way that achieves closure.

On high doses of DMT, it is possible for the entirety of one’s experience to be “compressed” into a triangle and then having that triangle projected onto our experience. You see how this would be a rather unusual and special kind of mathematical object, right? We’re dealing with a situation in which materializing a projection of the whole space onto a part of it radically changes the nature of the geodesics of the space. The triangle becomes a shortcut between various points that find their shortest distance by jumping into it. Now, in really exotic states, when multiple parallel streams are re-projecting the whole experience back onto itself after doing unique transformations to it (say, one “rolls up the experience into a tube”, another one “turns it into the surface of a sphere”, and yet another one “does this weird Hopf-fibration-like foliation of the space”) you have the emergence of phenomenal spaces that are extremely interconnected and will for the most part be a once-in-a-life-time encounter, as the combinatorial explosion of these feedback processes is so large we often have no hope of reconstructing specific and weird corner case.

Harmonic Simplification

Hundreds of spectral holograms can coexist in the shared screen at once. They do not need to collide directly. They are controlled by different modules, but they do “collapse” and get pushed into the same screen, which tries to reconcile/compile them into a single “point of view”. There are two steps. First the system tries to flatten all of the holograms in the main screen. Then the system lifts all of the subsystems that didn’t find a clear fit with each other into a higher-dimensional work space where the more fined-grained information is computed (and where many more kinds of rotations are available to do so). This way, the screen, in light of the multiple commenting parallel streams that “lift it”, can dynamically transform in much more general ways than what the screen itself could afford geometrically on its own. In that space their spectra interact more directly: modes beat against modes and compatible components find strange projections (along higher dimensional transformations) that allow them to click together. The screen’s own low frequency harmonics act as a constraint (they amplify the 2D and 3D symmetries found in among the gestalts as seen presented in the screen, cf. our computational model of cessation) and work as selection pressures for patterns that fit the logic of 3D space. Anything that persists must couple to, and be consistent with, the global modes of the screen (imposing familiar geometry), as well as the constraints being carried in/imported by each of the semi-independent modules.

When a stable configuration that ties together multiple other gestalts in a clean composition is found, the circuit produces a simplified gestalt that stands in for the group. In some cases it replaces it, but more typically the “summary representation” works as a kind of leader of the gestalts it’s summarizing. Alas, all gestalts are decaying, so the visible and impactful ones are only the most recent summaries. The summary gestalt also carries spectral content that matters for downstream coupling (how to “get along with the current screen as a whole”) and drops detail that would only introduce new conflicts. That surrogate then re-enters the loop as a new gestalt with its own spectral signature. The process is recursive, which makes most of experience be a strange process where summaries compose with other summaries, and the screen converges toward a coherent standing wave that is both globally coherent and locally consistent. The “infinite reflections in the eyes of beings” inside Indra’s Net e..g. “spider eyes” (eyes reflecting eyes, etc.) move in a way that is both consistent with the local geometry of the main screen (of access consciousness) as well as with the geometry of the network of connections and reflections. When you move an eye in an Indra’s Net, you move the _whole_ Net.

On ordinary mindstates gestalts have short half-lives, so the loop clears quickly and the screen doesn’t tend to have long-range temporal self-interactions. High-energy conditions such as high dose DMT or hard Jhanas extend those half-lives (cf. Tracer Effects). More gestalts remain in the screen for longer, more summaries are formed, and more couplings between gestalts become possible. The result is a scene where parts model each other and the whole and then re-express it in transformed form that interact with one another. This is the functional core of Indra’s Net phenomenology as I currently see it. And I believe we can have it come about naturally in such an optical circuit.

The Multitude Behind the Screen

We typically think the screen of consciousness is like this: you think you are just one witness looking at it. But what if it’s actually being broadcast to hundreds of different locations at once? And every one of those locations has a specialized intelligence that knows how to identify faces/mechanisms/connections on the screen and overlay that information on top of it for everyone else to see?

Neither recurrence nor resonance can solve the phenomenal binding problem, but if consciousness is a standing wave pattern trapped in a TIR pocket, then beam splitters that allow different modules to work simultaneously into a shared space just might.

From Lehar’s Cartoon Epistemology

Each of these specialized processing locations generates its own “interpretation of the scene”. Effectively, taking the shared space and applying specialized filters (try to resonate with it in a bunch of ways and see what sticks!), in turn modifying it in real time and contributing additional gestalts to the collective mix. Face recognition modules stamp facial harmonics onto visual patterns. Motion detection systems add their characteristic rhythms. Mood modules add jitter or laminar flow to attention. Memory systems contribute resonant modes that connect current perceptions to stored patterns. Emotional processing centers overlay affective spectral information that colors the entire scene (cf. citta).

The beam splitter is multimodal. The signal gets split and is sent simultaneously to somatic processing modules, auditory systems, and other sensory domains. Each domain receives the same fundamental holistic information (the _entire_ experience!) but processes it according to its own characteristic geometry, topology, and harmonic features. There’s likely a master screen that combines these three primary modalities (incl. visual, somatic, auditory) each contributing their own spectral signatures to the unified conscious experience.

Crucially, this conceptual framework might articulate the phenomenology we observer in how tactile-visual synesthesia works through spectral principles (cf. Roger Thisdell on Pure Perception). Synesthetic states can be thought of as “solitons” of the system: self-reinforcing wave packets that maintain their coherence while propagating their spectral information to the rest of the field across modalities. These solitons resonate with one another and with the broader spectral ecosystem in the screen, integrating interactions, and in turn lock together the gestalts contributed by different modules into stable multi-modal gestalts.

The sense of “Autonomous Entities”, and even more strikingly, the feeling of being a multitude on DMT might come from this mechanism becoming more “transparent”. The screen is always broadcast to many locations, but at baseline only a few have edit rights, with a strong and smart filter gating what reaches the authoritative version. On DMT many (perhaps most?) streams gain editing privileges at once, so an ecosystem of patterns grows in the shared space and coordinates through the screen without the intermediate central organizer (ego?) filtering who talks to who. This results in complex subagents interacting through the medium that can plot for and against you. Thus framework that accounts for Indra’s Net also explains Autonomous Entities: the competing clusters of coherence on DMT form hierarchical networks that bootstrap semi-parallel agency. As Steven Lehar hypothesizes (personal communication), these entities are facets of yourself: the central screen is being beamed to separate modules, each “witnesses” the whole scene, processes it, and then comments by beaming transformed gestalts back to the screen. Under normal conditions few streams are active; with DMT’s coupling kernel you may be “opening half the streams at once” (chaotically and hierarchically), creating literally “more witnesses of your experience.” Streams come together that usually don’t co-exist, and must thus negotiate how agency will be distributed among them.

A bit like the kid behind a reporter saying “mom! I’m on tv!” – many subagents can now broadcast their existence to the whole organism and seek like-minded shards to work on (artistic? political? cosmic?) projects with. Not all the shards understand each other’s communication style, so there is a lot of cross-talk that goes unrecognized by the whole yet is happening beneath the surface.

This way, the entities we encounter can be thought of as different parts of yourself gaining editing privileges on a shared space whose control room is usually locked and safeguarded. It is a multitude in the same way that you’re always already a multitude. But you’re usually following an algorithm that prevents “multiple parts talking at once”; with DMT that system is gone.

The Tracer Effect in Light of the Hologram Collective

As briefly touched upon already, on DMT (and other psychedelics/exotic states of consciousness), sensations (and gestalts) don’t decay at the same rate as normal. Every sensation you experience tends to flicker at a high frequency and linger for a while (depending on dose, could be over several seconds). These “tracers” hang around as afterimages that flicker characteristically fast at the 10-40hz range typically as they interact with one another. When the process that effectively works as a “compression engine” (gestalts summarizing pre-existing gestalts) tries to replace a cluster of gestalts with their simplified proxy, the older ones are still present and spectrally active (meaning, their vibrations still condition the screen and one another). The screen now contains both the compressed summary AND its constituent parents, so the next compression cycle captures the recursive echoes of patterns that should have vanished under normal circumstances (cf. don’t look at cauliflowers while on DMT!). It doesn’t take much imagination to see how this could lead to “fractal-like” patterns.

Overall, this creates a spectral feedback loop, where each new compression inherits more and more afterimages from previous cycles (until it reaches a dose-dependent homeostatic level). Instead of an orderly hierarchy of representations with conventional order, you get a sprawling pattern of self-referential holograms and time-loops, each quoting fragments (and partial impressions) of earlier generations, all resonating and cross-modulating each other. The compression engine, as it were, starts feeding on its own history, creating recursive patterns that reference themselves in increasingly complex ways. One of the key ingredients for the fractal quality of Indra’s Net!

Collective Harmony in Emergent Gestalts

Finally, any discussion of this process would be incomplete without at least mentioning valence. Individual holograms both float independently and they organize themselves into gestalt collectives. These collectives develop their own characteristic resonant modes, creating new spectral patterns that can influence the entire system from the top down. When you recognize a face, you are doing more than combining features such as eyes, nose, and mouth. Really, the face is a higher order gestalts: it is a collective interlocked “metagestalt” that has genuine causal power over how subsequent processing goes. The gestalts that make it up compromise a little on their own characteristic frequencies so that they can interlock as a group and genuinely form something more (and different) than the mere superposition of the parts. Importantly, each gestalt (of any order) tends to have both an intrinsic valence as well as a valence in relation to the other gestalts present. I would posit the intrinsic valence is the result of its internal consonance, dissonance, noise signature (CDNS) of the gestalt. Namely, how would this vibrate if it were the only element in the screen? Whereas valence in relation to other gestalts is the result of mutual consonance, dissonance, and noise between the gestalts.

Indra’s Net valence tends to be pretty extreme. Usually positive (or very positive), but at times negative or very negative. Yes, it is likely the case that if you want to pack as much consonance (mystical choruses, interdimensional massages, etc.) as possible in a finite volume like our screen of consciousness, probably creating a complex web of fractal connections allows you to maximize the number of pleasant relationships. Alas, be warned that fractal dissonances lurk in Indra’s Net too, and a “fractured” not quite complete Indra’s Net can be really disconcerting in some ways. It’s possible that peak positive valence resides in minimal-information-content experiences (as Michael Johnson’s Symmetry Theory of Valence posits), so high-energy high-symmetry states like 5-MeO-DMT are more likely to be leads for peak pleasure states that those catalyzed by DMT or similar. In either case, both the valence (and specifically aesthetic!) value as well as computational significance of Indra’s Net keeps it in the short list of most interesting states to study.

Discussion and Conclusions

Let’s recap. In our non-linear optical circuit, each iteration runs the same loop: the screen copies the whole scene to many modules, they transform their copies, the returns are then projected back onto the screen, and what fits with everything else stays. This iteration-by-iteration “handoff” from each of the modules and the screen as a whole gives continuity where small overlaps between iterations keep motion smooth. The system tends to a few stable objects because it keeps spectra that cooperate with each other and lets go of the rest. The screen is not (just!) a display (!), because it turns out to be where useful compute happens. Namely, where different modules can see the work of each other in real time, and negotiate together how to transform the scene in order to both fit the constraints of the screen as well as of each other.

Radical state changes affect how this loop behaves. With altered coupling dynamics, streams running at their own speed can lock to one another in the presence of strong kernel changes (e.g. when the “DMT coupling kernel” is applied indiscriminately to many systems at once). With tracers, the feedback intensifies across iterations and the negotiation becomes visible on the screen: edges, colors, textures, posture, points of view, trying to fit each with other. By default this tends towards hyperbolic geometry (as the gestalts drift into a more relaxed metric so that all of their idiosyncratic distances to one another can be embedded in some space and the gestalts get stitched together). But even more interestingly, when many modules hold the whole scene at once and write back versions that still predict it, you get Indra’s Net: each patch shows the whole through its own lens, and pulling on any part pulls on the rest too. When more streams get edit rights at the same time in tandem with the tracer effects, the modules negotiate domains of influence by both communicating through the screen and developing agent-like qualities. They all see the same broadcast, process it in their own way, and comment on it by projecting their gestalts back onto the screen. They feel alien because the usual gate that merges commentaries is relaxed, so their “signatures” stay distinct and you can watch them interact and develop new kinds of languages mid-flight.

We are in early days of BaaNLOC, but I am optimistic that it won’t take long for us to be able to code simulations of this optical circuit (and many variants) and then test whether they generate recognizably-DMT-like dynamics. From playing with toy models (to be released soon), I think we’re on track. But much remains to be done. Stay tuned 🙂

DMT for Cluster Headaches: Aborting and Preventing Extreme Pain with Tryptamines and Other Methods

“If we lived in a really sane society with a strong compassionate streak, every building would have something like a ‘Break in case of fire’ box… only this one would read ‘Break in case of cluster headache.’ Inside you’d find a pre‑charged DMT vape pen. That would be really nice.”

Announcement: Do you have experience using psychedelics to treat cluster headaches? Want to support science and advocacy in this area? Submit your personal and/or professional testimonial to our upcoming “ClusterFree” Open Letter initiative.


Sitting Down with Cluster Busters at Psychedelic Science 2025

One of the highlight moments for me at Psychedelic Science 2025 in Denver this June was conducting an interview for Bob Wold, founder of Cluster Busters, and Joe Stone, and Joe McKay who work alongside Bob in patient support and advocacy.  Our conversation covered a lot of ground, but I had one key strategic goal in mind: document, in their own words, why the humble DMT vape pen looks like a once‑in‑a‑generation breakthrough for the most painful condition that medicine has ever encountered.

“With a regular vape pen it’s usually one inhalation. Thirty seconds later the pain is gone. I hear a click in the middle of my brain and the attack is just off.” —Bob Wold

Their story plugs directly into QRI’s ongoing attempt to map the upper reaches of experience (QRI has the long-standing mission of mapping the state-space of consciousness, reverse engineer valence, and reduce suffering at scale). Our logarithmic scales of pleasure and pain shows that as one climbs up the pain (or pleasure) scales, phenomenal intensity rises far higher than common sense anticipates. The Heavy‑Tailed Valence hypothesis extends that insight to society at large and seeks to question the validity of current econometric approaches to collective wellbeing (cf. QALYs) in light of the fact that the extremes are not properly represented. From where we stand, it seems that a handful of wildly intense states do most of the moral damage (or good). Cluster headaches live in that fat tail, which is precisely why a 30‑second fix like DMT matters so much; perhaps as big of a collective hedonic breakthrough as, say, the discovery of anesthesia (in aggregate).

Put bluntly, if we care about total suffering, we need to care about cluster headaches. The time is now.


Interview Highlights Pertaining to DMT

  • DMT as an acute rescue
    One lungful (where the instructions typically say “three full breaths”) ends most attacks in under a minute. A second puff a minute later covers nearly all the rest. No tolerance shows up (acutely or chronically) which allows patients to repeat the dose whenever necessary.
  • Low psychedelic burden
    The dose is about a quarter of a psychedelic hit; enough to see some color enhancement but not enough for significant “trippiness”. Patients describe “a mild two‑beer buzz” or “the room takes on a golden tint” or “faint auras appear.” The mild level of psychedelia needed for this treatment makes bedside use practical, even for parents who need to stay functional the day after.
  • Why it beats psilocybin and LSD in the heat of battle
    Psilocybin and LSD still shine for cycle prevention, taken every five days, but they work on a timescale that makes them impractical for acute events. DMT is for the here‑and‑now (note Eleusinia founder says DMT also interrupt cycles according to her work at the retreat center). Joe Stone calls it “a game changer” because he can abort a 2AM ethical emergency (a cluster) and fall back asleep within 10 minutes. No need to have an expensive psychotherapy, a professional sitter, or trip killers on hand, let alone having to book a whole day to trip.
  • A hunch about endogenous DMT
    Bob’s shares his intuitive working model for how cluster headaches work (to be refuted or confirmed by science): an attack begins when natural DMT in the brain dips below a threshold (why do we even have DMT in our brains to begin with?). He hazards the guess that a quick DMT top‑up pulls the breaks and re‑establishes homeostasis. Others suggest that melatonin abnormalities in cluster patients add plausibility to his view, given the biochemical link between melatonin and endogenous tryptamine synthesis.
  • Pain drives the psychiatric condition, not the other way around
    One key insight I wanted to make sure to get on the record: chronic physical agony breeds depression, anxiety, and PTSD‑like flashbacks. Fix the pain and the mental distress often dissolves; no need for heroic doses or eight‑hour therapy sessions (as with e.g. psilocybin for depression specifically). Cultural over-emphasis on mental health as _the_ thing to treat with psychedelics might make sense from the point of view of a slowly expanding Overton Window; but the big hedonic payouts (freedom from hellish states of consciousness) are likely concentrated in their application to the reduction of extreme physical pain (see also).

Why This Matters

Alfredo Parra’s quantitative analysis suggests that cluster headaches may contribute more net misery than migraines, cancer pain, or even major depressive disorder once intensity is included (and a proper long-tail model and Monte Carlo simulations are taken into accont). Effective Altruist “pleasure-bean‑counters” (I say this affectionately!) please take note: extremely nasty but “rare” states can dominate the integral, and need urgent consideration.

From a consciousness‑research angle, the interview is another data point for why direct phenomenological investigation should guide ethics; here, patients, confronted with the reality of their own phenomenology, themselves have again clearly pioneered the treatment all the while mainstream research (unsurprisingly) slept through five decades of drug war.

Closing Thoughts

Imagine a fire‑alarm box on every hospital wall that reads “Break glass in case of cluster headache.” Inside we find a sober-looking, very boring but perfectly functional, pre‑filled DMT cartridge that delivers reliable 3mg hits (enough to feel a light buzz, not enough to trip significantly – certainly far short of any dose needed for entity contact or alien abduction experiences). This isn’t science fiction; it is what the data we’re seeing support.  Freedom from one of the most extreme demonic forces on Earth is, counterintuitively… Spice. Let’s shorten the path from patient innovation to standard‑of‑care and, in the process, erase one of the darkest corners of conscious experience forever. I believe we can achieve a Cluster-Free World within a few years if we put our minds and hearts to the task.

Hallucinations are not a problem at the doses we have people use and that seem to work the best, which are much smaller than a recreational dose. We aren’t recommending people take doses that will have them playing cards with a deer (you can’t trust them!). The doses are small (e.g. 1.5g of mushrooms). You’re supposed to get to about the “giggle”. Get to the “giggle point” and you’re good to go.Suicide or Psychedelics, Bob Wold at Horizons 2009


Resources and Further Reading:

How You Can Contribute:

  • Donate to Cluster Busters
  • Donate to QRI (earmark for “Cluster Headache Research and Advocacy”)
  • Donate to OPIS (Organization for the Prevention of Intense Suffering)
  • Share your testimonial if you’ve experienced relief through psychedelic therapy: Submit Here

Stay tuned for QRI’s upcoming Open Letter advocating for psychedelic access in treating severe pain conditions, the ClusterFree worldwide initiative.

Summer Travel Plans for 2025: Psychedelic Science, ASSC, Borderland

Hi everyone!

This week I’m in Denver for Psychedelic Science 2025 🙂

(the Psychedelic Science hero this year floating the relevance of non-linear optics as piece of the puzzle for psychedelic action? Perhaps see: 1, 2 – featured animation is from QRI collaborator Bijan Fakhri in the first link)

I’m going to be hosting a little get-together at The Dancers on Friday at noon, joined by Alien Insect (i.e. Andrew R Gallimore, writer of Alien Information Theory and Reality Switch Technologies) who will be eager to hear your entity contact stories (yes, even the unpleasant bits). 🙂

Call it a QRI Schelling Point: It’s for people interested in consciousness from a Qualia Research Institute angle. That is, efforts to map out the state-space of consciousness, algorithmically reduce psychedelic effects, describe the geometry of hallucinations, reverse engineering the correspondence between the shape and valence of an experience, and organizing Manhattan Projects of Consciousness-like gatherings with math, physics, meditation, and visual arts people to identify the equations behind psychedelic visuals, and so on; see also: psychedelic cryptography – secret messages only people high on LSD can read.

The Dancers are hard to miss. Find them right outside the convention center, between Champa str. and N. Speer blvd. They are gigantic.

Note: One of the key meetings I’m having at this conference will be with Bob Wold, the founder of Clusters Busters. When I was writing the Logarithmic Scales of Pleasure and Pain (see academic publication, h/t Chris Percy) in 2019 I stumbled upon various anecdotes that DMT at sub-hallucinogenic doses is capable of aborting (and then preventing) cluster headaches for a significant fraction of sufferers. Cluster headaches top the charts of painful conditions, and if aborting/preventing them can be safely and reliably done with DMT (and other psychedelics) then this might be one of the most promising directions for the suffering-focused wing of Effective Altruism (and anyone who cares about the true “amount of suffering” and how to reduce it). QRI collaborator and EA veteran Alfredo Parra has been working on quantifying the global burden of intense suffering, and concludes that there is a wide range of parameters for which cluster headaches turn out to cause more aggregate suffering than far more common conditions (e.g. migraines). Thus, along with a few other high-impact suffering-reduction interventions, at QRI we think that decriminalizing substances like DMT for painful conditions, and fostering education and access to them for cluster headache patients in particular, might be one of the most cost-effective ways of reducing the world’s suffering burden. That is, of course, alongside increasing the availability and adoption of other successful therapies (such as oxygen, for many). We are going to launch an Open Letter about this that we will disseminate strategically very soon, so stay tuned (I’ll ask you to sign it if you will!).

Importantly: if you or someone you know suffer from cluster headaches (or any other chronic pain condition that responds to psychedelic therapy) and want to share your testimonial with us in preparation for our launch, please fill out this form – ClusterFree Release Form.

See my interview with Jessica Khurana, founder of Eleusinia Retreat center in Mexico, the only psychedleic retreat center that specializes in offering its services to people who suffering from severe chronic pain of the sort that can be aided with psychedelic therapy.


In early July I’m traveling to Crete for ASSC, followed by the the ASSC Sattelite Event on ​Non-Ordinary States of Consciousness “QUALIUS“. And from there I plan to visit France for a couple of days (July 15-18) before I head to Sweden (to attend Borderland! I hope to see you there!) and finally will take a brief break in the UK early August on my way back. Please hit me up if you’d like to meet: will update this page with the corresponding QRI Schelling Point for each of my visits.

UPDATE: There will be a France QRI Meetup on the 16th of July, from noon to 6PM in Paris (8 Gal Saint-Marc, 75002). Then a Swedish QRI Meetup on the 18th at 6:30PM at Boulebar Rålambshov in Stockholm. Finally, UK Meetup will also be happening on August 3rd 5PM (until late) at Newspeak House: https://lu.ma/mmjwfq5e?tk=ydkN6X See you there! 🙂


Ps. I found this neat puzzle, see if you can figure it out 🙂

Presidential Inaugural Address of Andrés Gómez Emilsson

[Epistemic Status: fiction (in most timelines, that is); in my lane, having fun]

Place: The Equatorial Republic (pop. ~190M)

Time: 2032

My fellow citizens of this great Equatorial Republic,

Today, as I stand before you having accepted the solemn responsibility of the presidency, I am humbled by your trust and energized by the possibilities that lie before us. This administration marks not just a change in leadership, but a fundamental paradigm shift in how we approach governance, human welfare, and our collective future.

A New Era of Compassion Through Science

On this first day in office, I am announcing the formation of the National Hedonic Research Initiative. Let me be clear: extreme suffering can be worse than death itself. Nowhere is this more evident than in the case of cluster headaches—aptly named “suicide headaches” by medical professionals, a condition where the pain is rated significantly more severe than childbirth, kidney stones, or even gunshot wounds.

Through Executive Order 001, I am establishing the Cluster Headache Elimination Commission with an initial $2 billion in funding. The data is clear: approximately 3 million people worldwide suffer from this condition, spending nearly 5 million person-days annually in extreme suffering rated 9/10 or higher on pain scales. This Commission will:

  1. Create a nationwide tryptamine research and distribution network, prioritizing low-dose N,N-DMT, psilocybin, and LSD trials based on compelling evidence that these compounds can not only abort attacks but extend remission periods indefinitely for many patients
  2. Establish 200 specialized treatment facilities across the nation within 6 months with mandatory oxygen therapy and other proven abortive treatments
  3. Fund 50 research laboratories dedicated to advancing our understanding of pain relief mechanisms and developing targeted interventions for these conditions based on patient-reported outcomes

Additionally, I am directing the Department of Health to create the Pharmaceutical Innovation Directive focusing on anti-tolerance compounds for chronic pain patients, next-generation flumazenil analogs to reverse benzodiazepine dependence, and targeted solutions for other iatrogenic conditions that have been unconscionably neglected. These extreme forms of suffering represent the deepest moral emergency in our society, and their elimination is our highest priority.

Mapping the Hedonic Landscape: Beyond QALY

For too long, our policies have been guided by economic indicators and inadequate health metrics like Quality-Adjusted Life Years (QALY). The QALY framework fundamentally fails us by treating all human experiences as linearly equivalent and by capping wellbeing at an arbitrary “perfect health” that ignores the vast territory of heightened human potential.

The empirical evidence is compelling: our current metrics systematically undervalue both the depths of intense human experiences and the heights of human flourishing. As a result, we’ve created policies that address widespread but moderate challenges while neglecting concentrated instances of profound human experiences – both positive and negative.

Today, I am commissioning the first comprehensive Hedonic Landscape Observatory—a scientific assessment of the full spectrum of human experience that will:

  1. Develop more sensitive and accurate measurements of diverse human experiences across the wellbeing spectrum
  2. Map the neurological correlates of resilience and positive states to complement our understanding of health
  3. Create economic feedback loops that systematically reward businesses and institutions that demonstrably enhance quality of life
  4. Develop a new economic indicator—the Consciousness-Weighted Prosperity Index—that will appear alongside GDP in all government reporting

This initiative will ensure that governance decisions are evaluated not just by economic impact, but by their effect on the actual lived quality of conscious experience of our citizens—taking into account the true depth and breadth of human flourishing available to us.

Game Theory and Consciousness: A New Political Framework

We stand at an evolutionary crossroads. The old politics operated on outdated models that failed to recognize the fundamental relationship between consciousness and our collective future. Today, we begin the transition to a political framework that explicitly acknowledges the quality of conscious experience—as central to governance.

By Executive Order 002, I am establishing the Consciousness-Economy Integration Commission tasked with creating explicit feedback loops between consciousness research and economic selection pressures. This commission will:

  1. Develop metrics that quantify the wellbeing-enhancing potential of technologies, enabling investors to select for innovations that genuinely improve quality of life
  2. Create tax incentives for businesses that demonstrably improve the lived experiences of their employees and customers
  3. Establish a public research platform exploring the positive potential of consciousness, ensuring that discoveries about phenomenological wellbeing directly influence market forces

This systematic exploration of consciousness is not merely academic—it will fundamentally reshape our economic landscape by ensuring that technologies and policies that enhance human flourishing systematically outcompete those that merely optimize for shallow metrics. The implications for environmental policy, social welfare, and international relations are profound and far-reaching.

Transcending Tribal Politics Through Psychological Understanding

From this day forward, international diplomacy will operate with a new level of psychological sophistication. Through the newly formed Department of Psychological Architecture Analysis, we will explicitly model the subagent structure of world leaders and political movements, identifying when narcissism, psychopathy, or tribal thinking is driving decision-making.

International coalitions will be formed not just around shared interests, but around shared psychological awareness. This administration will not hesitate to name pathological dynamics when they appear on the world stage, while offering a path forward through a consciousness-centric yet pragmatic approach to governance.

I am also directing our diplomatic corps to explore new modalities for high-stakes negotiations. We will establish a Diplomatic Innovation Laboratory to research the application of empathy-enhancing protocols in negotiation settings where entrenched psychological barriers prevent resolution. When trillions of dollars and millions of lives hang in the balance of international agreements, we cannot afford to have negotiations hijacked by psychological defense mechanisms and tribal identification.

Just as we now understand that the pain of cluster headaches is objectively more severe than a migraine, despite superficially similar descriptions, we must develop precise language and metrics for the psychological architectures that drive international conflict. They are real, distortionary, and far from game-theoretically optimal. Only by seeing these structures clearly—and developing reliable methods to transform them—can we hope to address existential challenges that require genuine cooperation.

Longevity: The Right of Every Citizen

While extreme suffering can be worse than death, unnecessary death itself remains a profound tragedy and represents an incalculable loss of human potential. Today, I announce the formation of the National Longevity Institute with initial funding of $10 billion, coordinating research across public and private sectors to dramatically extend healthy human lifespan.

This institute will prioritize three areas:

  1. Senolytics and cellular reprogramming technologies to reverse biological aging
  2. Neural preservation techniques to maintain cognitive function
  3. Prevention of age-related suffering states through targeted interventions

The benefits of this research will not be reserved for the privileged few, but made available to every citizen as a basic right. Age-related suffering is not inevitable, and this administration will not accept it as such.

The Science of Awakening: Soteriology as a Research Target

Even as we pursue longevity, we must confront a fundamental truth: all things remain impermanent. Today, I am establishing the Institute for Contemplative Sciences with a mission to develop a rigorous scientific understanding of what traditions across time and cultures have called “awakening,” “enlightenment,” or “liberation.”

This research program will:

  1. Systematically study how humans throughout history have made peace with impermanence and transcended existential suffering
  2. Investigate the neurobiological and phenomenological correlates of awakening experiences across contemplative traditions
  3. Develop scalable, secular methods to help citizens process mortality, grief, and existential concerns within our scientific worldview
  4. Create interdisciplinary teams combining neuroscientists, contemplatives, philosophers, and clinicians to bridge ancient wisdom with modern scientific rigor

The ultimate human challenge is not merely to extend life, but to discover how to be fundamentally okay with the impermanent nature of existence. While various religious and philosophical traditions have offered paths to this goal for millennia, we now have the scientific tools to explore these states with unprecedented precision.

By creating a dialogue between contemplative wisdom and scientific method, we can forge new pathways for humanity to face its deepest existential challenges. This is not merely a spiritual pursuit—it is a practical necessity for a civilization grappling with the fundamental questions of meaning and mortality in an age of unprecedented technological power.

Understanding Exceptional States of Consciousness

The most profound states of human consciousness remain largely unexplored territory in scientific research. Today, I am directing the National Institutes of Health to establish the Center for Exceptional States of Consciousness (aka. The Super-Shulgin Academy) with a $5 billion initial investment, tasked with making sense of profoundly positive experiences across the full spectrum of chemically-facilitated and meditation-induced states.

This Center will:

  1. Create standardized protocols for psychedelic research, including 5-MeO-DMT with essential safeguards and contraindication screening, recognizing that while beneficial for many, it can induce challenging experiences in others—understanding these variables is crucial for responsible application
  2. Fund 25 dedicated research facilities specializing in Jhana acceleration techniques and other contemplative practices that achieve similar states without pharmacological intervention
  3. Develop a comprehensive empirical framework mapping the neural correlates of these heightened states while investigating both beneficial outcomes and adverse reactions to create predictive models for personalized approaches
  4. Prioritize sustainable MDMA production and research as a north star intervention, focusing on its potential for treating PTSD and enhancing empathetic connection while minimizing cardiovascular impact and developing protocols to mitigate tolerance and neurotoxicity concerns
  5. Translate findings into scalable interventions for depression, anxiety, and existential distress, ensuring that safety, accessibility, and individual neuropsychological differences guide all protocols

These states represent extraordinary territories of human wellbeing—regions of experience that offer not only therapeutic potential but a scientific window into the furthest reaches of human potential that we have barely begun to understand. Our commitment is to explore these states with both scientific rigor and ethical care, recognizing both their profound potential and the need for responsible stewardship.

Expanding Our Moral Circle: Non-Human Animal Consciousness

Our commitment to understanding consciousness and reducing suffering must extend beyond our own species. Today, I am establishing the Interspecies Consciousness Research Initiative with a dual mandate: rigorous scientific exploration and practical harm reduction.

This Initiative will:

  1. Develop objective metrics to quantify suffering in non-human animals, with immediate focus on factory-farmed animals where the concentration of suffering is most acute
  2. Allocate $3 billion annually to research and implement improved welfare standards for farmed animals while simultaneously investing in cultured meat technologies and plant-based alternatives
  3. Create a roadmap for the gradual, culturally sensitive phasing out of the most harmful animal agriculture practices over the coming decades, aligning economic incentives with ethical progress
  4. Establish the Wild Animal Welfare Research Program to cautiously explore the complex ethical landscape of wild animal suffering, acknowledging the immense scientific and ecological challenges involved

The ethical imperative is clear, but so is the need for careful, evidence-based approaches. We will neither rush interventions that could have unintended consequences nor hide behind complexity as an excuse for inaction when suffering is demonstrable and solutions are feasible. This balanced approach recognizes our ethical responsibilities without compromising scientific rigor or cultural realities.

Transforming Education: Experience, Don’t Memorize

A key pillar of this administration will be fundamentally reimagining education. Today, I announce the Consciousness Education Initiative that will transform how we develop young minds. This initiative rejects both outdated rote learning and any form of ideological indoctrination. Instead, it embraces a “see for yourself” approach where students:

  1. Learn meditation techniques alongside mathematics, building empirical skills for exploring internal states
  2. Study their own consciousness with the same rigor they apply to studying literature, using first-person methods complemented by third-person science
  3. Develop critical thinking by becoming aware of their own cognitive biases and subagent structures
  4. Understand the psychological architectures that drive political beliefs through evidence-based empirical investigations

The goal is not to tell students what to think about consciousness, but to give them the tools to explore their own minds with scientific precision and philosophical depth. This approach builds intellectual independence—teaching students to verify claims through direct experience rather than accepting them on authority, whether in consciousness studies or any other domain.

A Call to Action

My fellow citizens, I do not promise that these ambitious goals will be easy to achieve. They will require not just government action, but a transformation in how we approach science, governance, and our very understanding of what it means to be human.

But the stakes could not be higher. We have the opportunity to eliminate forms of suffering that have plagued humanity throughout history, to extend healthy life, to create social systems that support human flourishing, and to understand the very foundations of consciousness itself.

This is not a partisan agenda, but a human one. In fact, of consciousness itself. It transcends traditional political divisions and speaks to our shared desire for a world with less suffering and more joy, less confusion and more clarity, less conflict and more cooperation.

Let us begin this journey together, guided by compassion, informed by science, and dedicated to the proposition that the quality of conscious experience matters fundamentally—and that we have both the capability and the responsibility to improve it, in ourselves, our loved ones, and in the field at large.

Thank you, and may we move forward with wisdom, courage, and clear-eyed determination.

Infinite bliss!

[The crowd erupts in thunderous applause]

And now, ladies and gentlemen, please welcome the voted ‘most hedonic’ pop sensation of the year, performing their chart-topping anthem inspired by our vision for the future!

[Cue massive flashy fireworks as the stage transforms. Spotlights sweep across a diverse crowd of all ages beginning to dance as the music starts. Children, seniors, and everyone in between move to the rhythm. The singer emerges from beneath the stage on a rising platform surrounded by dancers in colorful neuron-patterned costumes, launching into their hit song about consciousness, wellbeing and the dawning of a new era of understanding…]

Conscious Dawn” – Presidential Lyrics

Ancient wisdom meets the future’s light
Through pain’s darkest valleys, we’ll find the heights
Mapping consciousness beyond what we’ve known
A nation where suffering won’t reign on the throne

Tribal boundaries dissolve in our sight
As senolytics set our cells aright
The hedonic landscape unfolds like a scroll
Where DMT whispers truths to the soul

From cluster headaches to enlightened minds
Transcending metrics that keep us blind
Our moral circle widens beyond human skin
Wild animal welfare, a new dawn begins

Science awakens what sages once taught
Not just to live long, but find what we’ve sought
A republic where bliss is more than a dream
Infinite consciousness—our birthright supreme

Announcing: QUALIUS Retreat in Crete (July 10-14, 2025)

I’m excited to announce QUALIUS, an upcoming post-ASSC retreat on the topic of non-ordinary states of consciousness, taking place July 10–14, 2025, in Ligres, Crete. Organized by the ALIUS and QRI, the retreat will bring together researchers working at the intersection of psychometrics, VR, computational modeling, and contemplative practice. It’s structured around four thematic tracks: measuring subjective effects, studying altered states using virtual reality, integrating lived experience into consciousness research, and formalizing the structure of non-ordinary states. QRI is helping with support for the retreat and by leading the fourth track, contributing our latest tools and frameworks for modeling the fine-grained structure of experience. Our approach emphasizes the phenomenal character of states of consciousness—the texture and structure of experience—over the intentional content, or what the experience is about. Conceptual tools like the Guide to Writing Rigorous Reports of Exotic States of Consciousness and software tools like the QRI’s Tracer Tool give a flavor of our methodology, but we’ll be showcasing more advanced, unpublished systems currently being integrated into active studies.

This post-ASSC 2025 satellite event will serve as an interdisciplinary workshop retreat to advance research on consciousness, altered states, and computational phenomenology. It will integrate perspectives from neuroscience, VR, computational modeling, and philosophy, fostering collaboration among researchers with a shared interest in non-ordinary conscious states. A key focus will be on the measurement of subjective effects in altered states research, exploring innovative experiential approaches using VR to induce and study these phenomena. The workshop will also highlight neurophenomenological methods that bridge first-person experience with third-person data, particularly at the intersections of art and neuroscience. Through focused discussions, cross-disciplinary talks, and collaborative sessions, participants will explore formal models of consciousness, including mathematical frameworks and neural modeling approaches. The workshop aims to establish a long-term research consortium, promoting sustainable partnerships and open collaboration to bridge empirical and theoretical perspectives in the study of altered states.
The retreat is designed as a smaller, more intimate gathering of around 35 researchers with a shared interest in altered states of consciousness. Unlike the main conference, which primarily focuses on published work, this retreat will emphasize ongoing and future research, fostering discussions that lead to new collaborations. The aim is to create a space where researchers can connect organically, exchange ideas, and explore potential synergies—whether intellectual, financial, or infrastructural—through a bottom-up approach driven by participant interactions and shared interests.
QUALIUS: ASSC Sattelite Event on Non-Ordinary States of Consciousness

Acknowledgements

Thanks to George Fejer for coming up with this initiative and offering to collaborate with QRI. Thanks to Till Holzapfel for introducing us and suggesting collaboration possibilities (and everyone who recently participated in the QRI Meetup in Amsterdam, many of whom will be joining this event!).

The retreat is made possible by the assembly of an extraordinary team across four research tracks:

Track 1 – Measuring Subjective Effects (organized by Timo Torsten Schmidt and Cyril Costines, see: CIRCE). This track develops open-science strategies for capturing and comparing altered states using validated psychometrics and large-scale data platforms.

Track 2 – Virtual Reality for Altered States (Curated by Keisuke Suzuki, Pawel Motyka, and George Fejer). This track explores how VR and cybernetic feedback systems can induce, modulate, and investigate non-ordinary experiences. Includes contributions from the Viscereality Project.

Track 3 – Lived Experience in Consciousness Research (by Mar Estaralles and Jonas Mago), which explores how introspection, contemplative practice, and lived first-person perspectives can be integrated into rigorous consciousness research.

And QRI collaborators working on Track 4 – Formalizing the Non-Ordinary State Space (full list of collaborators TBA soon). This fourth track focuses on computational and phenomenological modeling of non-ordinary states. We’ll explore how structural features of experience can be visualized, compared, and potentially modulated, and how to integrate these replications into rigorous studies.

We’re grateful to the ALIUS Research Group for setting up this event, ASSC for accepting the retreat as an official satellite event of the conference, and to the broader consciousness research community for cultivating a space where formal theory, lived experience, and empirical investigation can converge.

If your work lives in this space (or if you’d like it to) consider applying today.

Infinite bliss!
Andrés 🙂

Cel Animation as a Key Metaphor to Model DMT Hallucinations

Pieces of Khet, a popular laser chess-like game.

[Epistemic Status: Taking Phenomenology Seriously – Allowing Myself to Speculate Profusely]

Introduction: Laser Chess as a Metaphor for the Brain as a Non-Linear Optical Computer

In Laser Chess (a synecdoche for games of this sort), players arrange various kinds of pieces that interact with lasers on a board. Pieces have “optical features” such as mirrors and beam splitters. Some pieces are vulnerable to being hit from some sides, which takes them off the board, and some have sides which don’t interact with light but merely absorb it harmlessly (i.e. shields). You usually have a special piece which must not be hit, aka. the King/Pharaoh/etc. (or your side loses). And at the end of your turn (once you’ve moved one of your pieces) the laser of your color is turned on, and its light comes out of one of your pieces in a certain direction and then travels to wherever it must (according to its own laws of behavior). Usually when your laser hits an unprotected side of a piece (including one of your own pieces), the targeted piece is removed from the board. Your aim is to hit and remove the special piece of your opponent.

Example of a beam splitter optical element (source)

What makes this game conceptually more interesting than Chess isn’t just that its openings haven’t been thoroughly studied (something Bobby Fischer complained about with Chess), but rather that the light’s path depends on all pieces functioning together as a whole, adding a layer of physical embodiment to the game. In other words, Laser Chess is not akin to Chess 960, where the main feature is that there are so many openings that the player needs to rely less on theory and more on fluid visual reasoning. It’s more, at least at the limit, like the difference between a classical and a quantum computer. It has a “holistic layer” that is qualitatively different than the substrate upon which the game normally operates.

In Laser Chess, the “piece layer” is entirely local, in that pieces can only move around in hops that follow local contextual rules. Whereas the “laser layer” is a function of the state of the entire board. The laser layer is holistic in nature because it is a function of the entire board at once. It’s the result of, at the limit, letting the light go back and forth an infinite number of times and let it resolve whatever loop or winding path it may need to go through. You’re looking for the standing wave pattern the light wants to resolve on its own.

Online Laser Chess (source) – the self-own of the blue player is understandable given the counter-intuitive (at first) way the light ends up traveling.

In Laser Chess you move your piece to a position you thought was safe just to be hit by the laser because the piece itself was what was making that position safe! The beginner player is often startled by the way the game develops, which makes it fun to play for a while. The mechanic is clever and to play you need to think in ways perhaps a bit alien to a strict Chess player. But at the end of the day it’s not that different of a game. You do end up using a lot of calculations (in the traditional Chess sense of “mental motions” you keep track of to study possible game trees), and the laser layer only changes this slightly.

When the laser beam hits one of the mirrors, it will always turn 90 degrees, as shown in the diagrams. The beam always travels along the rows and columns; as long as the pieces are properly positioned in their squares, it will never go off at weird angles.
Khet: The Laser Game Game Rules

In Laser Chess, the behavior of light is not particularly impressive. After all, thinking about the laser layer in terms of simple local rules is usually enough (“advance forward until you hit a surface”, “determine the next move as a function of the type of surface you hit”, etc.). The game is quite “discretized” by design. Tracing a single laser path is indeed easy when the range of motion and possible modes of interaction are precisely constructed to make it easy to play. It’s uncomplicated by design. The calculations needed to predict the path of the light never becomes intractable: the angles are 45°/90° degrees, the surfaces cleanly double, reflect, absorb the light, etc.

Laser Chess, now with weird polygonal pieces and diffraction effects!

But in a more general possible version of Laser Chess the calculations can become easily intractable and far more interesting. If we increase the range of angles the pieces can be at relative to each other (or make them polygons) we suddenly enter states that require very long calculations to estimate within a certain margin of error. And if we bring continuous surfaces or are allowed to diffract or refract the light we will start to require using the mathematics that have been developed for optics.

Edge diffraction (source)

In a generalized Laser Chess, principles for the design of certain pieces could use specific optical properties, like edge diffraction:

If light passes near the edge of a piece (rather than hitting it directly), it could partially bend around the object instead of just stopping. Obstacles wouldn’t provide perfect shadows, allowing some light to “leak” around corners in a predictable but complex way. Example: A knight-like piece could have an “aura of vulnerability” where light grazing its edge still affects pieces behind it.

Instead of treating lasers as infinitely thin lines, beams could diffract when passing through narrow gaps or slits. This would allow for beam broadening, making it possible to hit multiple pieces even if they aren’t in a direct line. Example: If a piece has a slit or small hole, it could scatter the laser into a cone, potentially hitting multiple targets.

And so on. And there is a staggering number of optical properties to select from. From refraction, iridescence, polarization, birefringence, and total internal reflection, each offering unique strategic possibilities. And then there we also have their mutual interactions to consider. Taking all of this into account, a kind of generalized Laser Chess complexity hierarchy arises:

  • The simplest Laser Chess variants are mostly geometric, with straightforward ray tracing. They benefit from a physical laser or a computer, but don’t require it.
  • Intermediate complexity comes after adding diffraction, refraction, and wave optics, requiring Fourier transforms and wave equations to analyze the beam behavior. It requires a physical laser or a computer to be played, because mental calculation won’t do.
  • And high complexity variants come about when you take into account quantum-inspired effects like interference and path integrals, leading to both deterministic and probabilistic gameplay mechanics where players need to take into account complex superpositions and calculate probabilities. It requires either carefully designed cases for computers to be sufficient; physical embodiment might become necessary above a certain complexity.

The Self as King

Let’s start to draw the analogy. Imagine the special piece as your sense of self, the piece that must be protected, while the other pieces represent state variables tuning your world-model. In some configurations, they work together to insulate the King, diffusing energy smoothly across the board. In others, a stray beam sneaks through—an unexpected reflection, a diffraction at just the wrong angle—and suddenly, the self is pierced, destabilized, and reconfigured. The mind plays this game with itself, setting up stable patterns, only to knock them down with a well-placed shot.

The field of consciousness, poetically speaking, is a lattice of light shifting under the pressure of attention, expectation, and the occasional physiological shear. But whether or not the awareness that corresponds to the light is self-aware depends on the precise configuration of this internal light path: some ways of arranging the board allow for a story to be rendered, where a sense of self, alive and at the center of the universe, is interpreted as the experiencer of the scene. Yet the scene is always being experienced holistically even if without a privileged center of aggregation of the light paths. The sense of a separate, divided witness might be a peculiar sleight of hand of this optical system, a kind of enduring optical illusion generated by what is actually real: the optical display.

BaaNLOC

The Brain as a Non-Linear Optical Computer (BaaNLOC) proposes that something like this happens in the brain. The brain’s physical structure – its neural wiring, synaptic connections, and the molecular machinery of neurons – maps onto a set of “optical” properties. These properties shape how electromagnetic waves flow and interact in neural tissue.

Think of a sensory stimulus, within the Laser Chess analogy of the brain’s computational substrate, as akin to a brief blip from a laser. As the stimulus-triggered electrochemical signal propagates through neural circuits, its path is shaped by the brain’s “optical” configuration. Excitatory and inhibitory neurons, tuned to different features, selectively reflect and refract the signal. The liquid crystal matrix encoded in the molecular structure of intracellular proteins might also play a role, perhaps modulating the electromagnetic medium through which the signal must travel.

Where these signals meet, they interfere, their wave properties combining to amplify or cancel each other out. BaaNLOC posits that the large-scale interference pattern and the non-linear emergent topological structure of these interacting waves constitutes the contents of subjective experience.

Attention and expectation act as a steady pressure on this system, stabilizing certain wave patterns over others, like a piece the board influencing the path of the laser. What we perceive and feel emerges from the EM standing waves shaped by this top-down influence.

Psychedelics and BaaNLOC

Psychedelics, in this framework, temporarily alter the optical properties of the brain. Abnormal patterns of signaling elicited by drugs like DMT change how neural waves propagate and interact. The result is a radical reconfiguration of the interference patterns corresponding to conscious experience.

The BaaNLOC paradigm seeks to bridge the brain’s electrodynamics with the phenomenology of subjective experience by framing neural processes in terms of EM wave dynamics and electrostatic field interactions. While the precise mapping between neural activity and optical properties remains an open question (we have some ideas), the process of searching for this correspondence is already generative. The brain’s electrostatic landscape is not uniform; instead, it consists of regions with varying permittivity and permeability, which affect the way EM waves propagate, reflect, and interfere. Axonal myelination influences conduction velocity by altering the dielectric properties of neural pathways, shaping the timing and coherence of signals across brain regions. Dendritic arbor geometry sculpts synaptic summation, forming local electrostatic gradients that influence how waves superpose and propagate. Cortical folding affects field interactions by modulating the spatial configuration of charge distributions, altering the effective permittivity of different regions and creating potential boundaries for wave interference. These parameters suggest that experience may be structured not only by firing patterns but also by the electrostatic properties of the substrate itself. If perception is mediated by standing waves in an EM field shaped by the brain’s own internal dielectric properties, then the phenomenology of experience may correspond to structured resonances within this medium, much like how lenses manipulate light by controlling permittivity gradients. Investigating these interactions could illuminate the connection between the brain’s physical substrate and the emergent contours of conscious experience.

You can even do spectral filtering of images with analogue Fourier transforms using optical elements alone. Think about how this optical element could be used right now in your brain to render and manufacture your current reality:

Analogue Fourier transform and filtering of optical signals. (Gif by Hans Chiu – source).

Real-time analog Fourier decomposition of sensory information would be a powerful computational tool, and we propose that the brain’s optical systems leverage this to structure our world-simulation.

In this framework, certain gestalt patterns act as energy sinks, analogous to standing waves at resonant frequencies. These patterns serve as semantic attractors in the brain’s harmonic energy landscape, forming local minima where perceptual content naturally stabilizes. These attractor surfaces are often semi-transparent, refractive, diffractive, or polarizing, vibrating in geometry-dependent ways. “Sacred geometry” corresponds to vibratory patterns that are maximally coherent across multiple layers at once, representing low-energy states in the system’s configuration space. When the world-sheet begins to resemble these structures, it “snaps” into symmetry, as this represents an energy minimum. This aligns with Lehar’s field-theoretic model of perception, where visual processing emerges from extended spatial fields of energy interacting according to lawful dynamics. Given that such self-organizing optical behavior is characteristic of liquid crystals, it is worth considering whether the brain’s substrate exploits liquid-crystalline properties to facilitate these energy-minimizing transformations.

It is within this paradigm that the following idea is situated.

DMT Visuals as Holographic Cel Animation in a Nonlinear Optical Medium

DMT visuals (and to a lesser extent those induced by classic psychedelics in general) might be understood as semi-transparent flat surfaces in a non-linear optical medium, akin to the principles behind cel animation. Source: How It’s Made | Traditional Cel Animation*

Cel animation uses partially transparent layers to render objects in a way that allows them to move independent of each other. In cel animation the features of your world are parsed in a suspiciously anthropomorphic way. If you change a single element in an unnatural way, you find it rather odd. Like it breaks the 4th wall in a way. You can get someone to blink an eye or move their mouth in the absence of any other movement. What kind of physical system would do that? One that was specifically constructed for you as an interface.

Imagine a child flipping through a book of transparent pages, each containing a fragment of a jaguar, a palm, a tribal mask. As the pages overlay, the scene assembles itself — not as a static image, but as a living tableau (somebody please fire the Salesforce marketing department for appropriating such a cool word). Now imagine those transparencies aren’t merely stacked; they are allowed to be at odd angles relative to each other and to the camera:

This is the basic setup. The idea is that on DMT, especially during the come-up at moderate doses (e.g. reaching Magic Eye-level), the sudden appearance of 2D gestalts in 3D (which are then “projected” to a 2.5D visual field) is a key phenomenological feature. The rate of appearance and disappearance of these gestalts is dose-dependent, same as the kind of interactions they come enabled with. From here, we can start to generalize this kind of system to better capture visual (and somatic, as we will see) features of a DMT experience in its full richness and complexity. Just as in the case of Laser Chess, where we began with a basic setup and then explored how non-linear optics would massively complicate the system as we introduce interesting twists, here as well we begin with cel animation planes in a 3D space and add new features until they get us somewhere really interesting.

An important point is that DMT cel-animation-like phenomenology seems to have some hidden rules that are difficult to articulate, let alone characterize in full because it interacts with the structure of our attention and awareness. Unlike actual cel animation, the flat DMT gestalts don’t require a full semi-transparent plane to come along with them – they are “cut” already, and yet somehow can “float” just fine. Importantly, even when you have extended planes and they are, say, rotating, they can often intersect. Or rather, the fact that they overlap in their position in the visual field does not mean that they will interact as if they were occupying the same space. Whether two of these gestalts interact with each other or not depends on how you pay attention to them. There is a certain kind of loose and relaxed approach to attention where they all go through each other, as if entirely insubstantial. There is another kind of way of attending where you force their interaction. If you have seven 2D gestalts floating in your visual field, by virtue of the fact that you only have so many working memory slots / attention streams, it is very difficult to keep them all separate. At the same time, it is also very difficult to bring them all together. More typically, there is a constantly shifting interaction graph between these gestalts, where depending on how emergent attention dynamics of the mind go, clusters of these gestalts end up being simultaneously being payed attention to, and thus blend/unify/compete and constructively/destructively interfere with one another.

One remarkable property of these effects is that 2D gestalts can experience transformations of numerous kinds: shrinking, expanding, shearing, rotating, etc. Each of these planes implicitly drags along a “point of view”. And one of the ways in which they can interact is by “sharing the same point of view”.

Cels as Planes of Focus

One key insight is that the 2D surfaces that make up these cels in the visual field on a moderate dose of DMT seem to be regions where one can “focus all at once”. If you think of your entire visual field as an optical display that can “focus” on different elements on a scene, during normal circumstances it seems that we are constrained to focusing on scenes one plane at a time. Perhaps we have evolved to match as faithfully as possible the optical characteristics of a camera-like system with only one plane of focus, and thus we “swallow in” the optical characteristics of our eyes and tend to treat them as fundamental constraints of our perception. However, on DMT (and to a lesser extent other psychedelics) one can see multiple planes “in focus” at the same time. Each of these gestalts is typically perfectly “in focus” and yet with incompatible “camera parameters” to the other planes. This is what makes, in part, the state feel so unusual: there is a sense in which it feels as if one had multiple additional pairs of eyes with which to observe a scene.

A simple conceptual framework to explain this comes from our work on psychedelic tracers. DMT, in a way, lets sensations build up in one’s visual and somatic field: one can interpret the multiple planes of focus as lingering “focusing events” that stay in the visual field for much longer, accumulating sharply focused points of view in a shared workspace of visual perspectives.

Another overall insight here is that each 2D gestalt in 3D space that works as an animation cel is a kind of handshake between the feed from each of our eyes. Conceptually, our visual cortex is organized into two hierarchical streams with lateral connections. Levels of the hierarchy model different spatial scales, whereas left-vs-right model the eye from which the input is coming from. At a high-level, we could think of each 2D cel animation element as a possible “solution” for stable attractors in this kind of system: a plane through which waves can travel cuts across spatial scales and relative displacements between the image coming from each eye. In other words, the DMT world begins to be populated by possible discrete resonant mode attractors of a network like this:

The Physics of Gestalt Interactions

As the 2D cels accumulate, they interact with one another. As we’ve discussed before, our mind seems to have an energy function where both symmetrical arrangements and semantically recognizable patterns work as energy sinks. The cel animation elements drift around in a way that tries to minimize their energy. How energized a gestalt is manifests in various ways: brightness of the colors, speed of moment, number of geometric transformations applied to it per second, and so on. When “gestalt collectives” get close to each other, they often instantiate novel coupling dynamics and intermingle in energy-minimizing ways.

Holographic Cel Animation

Since each of the cels in a certain sense corresponds to a “plane of focus” for the two eyes, they come with an implicit sense of depth. As strange as it may sound, I think it is both accurate and generative (or at the very least generative!) to think of each cel animation element as a holographic display.

(source)

I think this kind of artifact of our minds (i.e. that we get 2D hologram-like interacting hallucinations on DMT) ultimately sheds light on the medium of computation our brain is exploiting for information processing more generally. Our mind computes with entire “pictures” rather than with ones and zeros. And the pictures it computes with are optical/holographic in nature in that they integrate multiple perspectives at once and compress entire complex scenes into manageable lower dimensional projections of them.

Each cel animation unit can be conceptualized as a holographic window into a specific 3D scene. This connects to one of the striking characteristics of these experiences. In the DMT state, this quality manifests as a sense that the visualized content is “not only in your mind” but represents access to information that exists beyond the confines of personal consciousness. The different animated elements appear to be in non-local communication with one another, as if they can “radio each other” across distances. At the very least their update function seems to rely both on local rules and global “all-at-once” holistic updates (much akin to the way the laser path changes holistically after local changes in the location of individual pieces).

This creates the impression that multiple simultaneous narratives or “plots” can unfold at “maximum speed” concurrently. Each element seems capable of filtering out specific signals from a broader field of information, tuning into particular frequencies while ignoring others. The resulting 2.5D/3D interface serves as a shared context where gestalts that communicate through different “radio channels” can nonetheless interact coherently with each other in a shared geometric space.

Credit: @smallfly (read more)

The above VR application being developed by Hugues Bruyere at DPT (interesting name!) reminded me of some of the characteristic visual computation that can take place on DMT with long-lasting holographic-like scenes lingering in the visual field. By paying attention to a group of these gestalts all at once, you can sort of “freeze” them in space and then look at them from another angle as a group. You can imagine how doing this recursively could unlock all kinds of novel information processing applications for the visual field.

Visual Recursion

Each cel animation element can have a copy of other cel animation elements seen from a certain perspective within it.

Because each animation cel can display an entire scene in a hologram-like fashion, it often happens that the scenes may reference each other. This is in a way much more general than typical video feedback. It’s video feedback but with arbitrary geometric transformations, holographic displays, and programmable recursive references from one feed to another.

The Somatic Connection

(Source)

One overarching conceptual framework we think can help explain a lot of the characteristics of conscious computation is the way in which fields with different dimensionalities interact with one another. In particular, we’ve recently explored how depth in the visual field seems to be intimately coupled with somatic sensations (see: What is a bodymind knot? by Cube Flipper, and On Pure Perception by Roger Thisdell). This has led to a broad paradigm of neurocomputation we call “Projective Intelligence“:

The projective intelligence framework offers a conceptual foundation for how to make sense of the holographic cels. Our brains constantly map between visual (2.5D) and tactile (3D) fields through projective transformations, with visual perceptions encoding predictions of tactile sensations. This computational relationship enables the compression of complex 3D information into lower dimensions while highlighting patterns and symmetries (think about how you rotate a cube in space in order to align it with the symmetries of our visual field: a cube contains perfect squares, which becomes apparent when you project it onto 2D in the right way).

In altered states like DMT experiences, these projections multiply and distort, creating the characteristic holographic windows we’re discussing: multiple mappings occur between the same tactile regions and different visual areas. This explains the non-local communication between visual elements, as the visual field creates geometric shortcuts between tactile representations using the visual field. It’s why separated visual elements appear to “radio each other” across distances: they can be referencing the same region of the body!

The recursive qualities of these holographic cels emerge when the “branching factor” of projections increases, creating Indra’s Net-like effects where everything reflects everything else. The binding relationships that arise in those experiences can generate exotic topological spaces: you can wire your visual and somatic field together in such a way that the geodesics of attention find really long loops involving multiple hops between different sensory fields.

In brief, consciousness computes with “entire pictures” which can interact with each other even if they have different dimensionalities – this alone is one of the key reasons I’m bullish on the idea that carefully depicting psychedelic phenomenology will open up new paradigms of computation.

Collective Intelligence Through Transformer-like Semantics

In addition to the geometric holographic properties of these hallucinations, the semantic energy sink also operate in remarkably non-trivial ways. When two DMT patterns interact, they don’t just overlap or blend like watercolors. They transform each other in ways that look suspiciously like large language models updating their attention vectors. A spiral might encounter a lattice, and suddenly both become a spiral-lattice hybrid that preserves certain features while generating entirely new ones. If you’ve played with AI image generators, you’ve seen how combining prompt elements creates unexpected emergent results. DMT visuals work similarly, except they’re computing with synesthetic experiential tokens instead of text prompts. A hyperbolic jewel structure might “attend to” a self-dribbling basketball, extracting specific patterns that transform both objects into something neither could become alone.

Some reports suggest that internalizing modern AI techniques before a DMT trip (e.g. spending a week studying and thinking about the transformer architecture) can power-up the intellectual capacities of “DMT hive-minds”. If your conceptual scheme can only make sense of the complex hallucinations you’re witnessing on ayahuasca through the lens of divine intervention or alien abductions, the scenes that you’re likely to render will be restricted to genre-conforming semantic transformations that minimize narrative free energy. But if you come in prepared to identify what is happening through the lens of non-linear optics and let the emergent subagents (clusters of gestalts that work together as agentive forces) self-organize as an optical machine learning system, you may end up summoning novel (if still very raw and elemental) kinds of conscious superintelligences.

Conclusion: The Gestalt Amphitheater

In ordinary consciousness, we meticulously arrange our perceptual pieces to protect the King (our sense of self) ensuring that the laser of awareness follows predictable, habitual paths. The optical elements of our world-simulation are carefully positioned to maintain the stable fiction that we are unified subjects navigating an objective world.

DMT radically rearranges these pieces, creating optical configurations where “the light of consciousness” reflects, refracts, and diffracts in unexpected ways. The laser no longer follows familiar paths but moves along a superposition of paths through the system in patterns that reveal the constructed nature of the central self and of the simulation as a whole. The King (that precious sense of being a singular perceiver) stands exposed as what it always was: not an ontological primitive but an emergent property of a particular configuration where “attention field lines converge.”

The projective intelligence framework helps us understand this phenomenology. Our brains constantly map between visual (2.5D) and tactile (3D) fields through transformations that encode predictions and compress complex information. In DMT states, these projections multiply and distort, creating “holographic windows” where multiple mappings occur simultaneously. This explains the non-local communication between visual elements: separated gestalts appear to “radio each other” across distances because multiple tactile sensations can use the visual field as a shortcut to resonate with each other and vice versa.

The emergent resonant attractors of the whole system involve many such shortcuts. When the recursive projections find an energy minima they lock in place, at least temporarily: the complex multi-sensory gestalts one can experience in these states capture layers of recursive symmetry as information in sensory fields is reprojected back and forth, each time adapting to the intrinsic dimensionality of the field onto which it is projected. “Sacred geometry” objects on DMT are high-valence high-symmetry attractors of this recursive process.

The DMT state doesn’t “scramble consciousness” (well, not exactly); rather, it reconfigures its optical properties, allowing us to witness the internal machinery that normally remains hidden in our corner of parameter space. These visuals aren’t “hallucinations” in any conventional sense. That would imply they’re distortions of some more fundamental reality. Instead, I think they’re expressions of our brain’s underlying optical architecture when highly energized and fragmented, temporarily freed from the sensory constraints that normally restrict our perceptual algorithms.

By understanding the brain as a kind of non-linear optical computer, and consciousness as a topologically closed standing wave pattern emergent out of this optical system, we may develop more sophisticated models of how the brain generates world simulations. And perhaps one day (soon!) even discover new computational paradigms inspired by the way our minds naturally process information through multiple holographic dimensional interfaces at once. Stay tuned!


*animations made with the help of Claude 3.7, when otherwise not specified.

From Neural Activity to Field Topology: How Coupling Kernels Shape Consciousness

This post aims to communicate a simple yet powerful idea: if you have a system of coupled oscillators controlled by a coupling kernel, you can use it to not only “tune into resonant modes” of the system, but also as a point of leverage to control the topological structure of the fields interacting with the oscillators.

This might be a way to explain how topological boundaries are mediated by neuronal activity, which in turn can be modulated by drugs/neurotransmitter concentrations, and in this way provide a link between neurochemistry and the topological structure of experience. Two things fall out of this: First, we might have the conceptual tools to link the creation of global topological boundaries (which at QRI we postulate are what separates a moment of experience from the rest of the universe) and neural activity. And second, in turn, we might have the ability to explain as well the way changes in oscillator/neural activity give rise to differently internally structured topologies (which together with a way of interpreting the mapping between topology of a field and its phenomenology) can help us explain things like the phenomenological differences between states of consciousness triggered by the ingestion of drugs as different as DMT and 5-MeO-DMT. In other words, this post is pointing at how we can get topological structure out of oscillatory activity – and thus explain how conscious boundaries (both local and global) are modulated both natively and through neuropharmacological interventions. It’s an algorithmic reduction with potentially very large explanatory power in the realm of consciousness research that only now is becoming conceptually accessible thanks to years of research and development at QRI.

Let’s start with a Big Picture Summary of the framework:

QRI aims to develop a holistic theoretical framework for consciousness. This latest iteration aims to integrate electromagnetic field theories of consciousness, connectome-specific harmonic waves, coupling kernels, and field topology in a way that might be capable of providing both explanatory and predictive power in the realm of phenomenology and its connection to biology. While this is an evolving framework, I see a lot of value in sharing the general idea (the “big picture”) we have at the moment to start informing the community and collaborators about how we’re thinking about unifying frameworks for understanding consciousness at the moment. The core elements of the Big Picture are:

  • Coupling Kernels as Neural-Global Bridge: The coupling kernel serves as a critical bridge between local neural circuitry and global brain-wide behavior. As demonstrated in Marco Aqil‘s work, when scaling up from neural microcircuits, the power distribution across different system harmonics can be modulated through coupling kernel parameters. This is something we arrived at independently last year in a very empirical and hands-on way, but Marco’s precise mathematical framework provides a solid theoretical foundation for this connection.
  • Geometric Constraints on Coupling Effects: The underlying geometry of a system fundamentally shapes how coupling kernels manifest their effects: resonant modes accessible through coupling kernels differ significantly between scale-free and geometric networks. Within geometric networks, specific geometries and dimensionalities generate characteristic resonant patterns. Thus, a single “high level” effect like a change in coupling kernel can have a wide range of different effects depending on the type of network/system to which it is applied.
  • Network Geometry Interactions and Projective Intelligence: A fundamental computational principle emerges from the interaction between networks of different geometries/topologies. This underlies “projective intelligence” (or more broadly, mapping/functional intelligence) – as exemplified by the interaction between the 2D visual field and 3D somatic field.
  • Topological Solution to the Boundary Problem: The topological solution to the boundary problem elucidates how physically “hard” boundaries with causal significance and holistic behavior could explain the segmentation of consciousness into discrete experiential moments.
  • Internal Topology and Phenomenology: The internal topological complexity within a globally segmented topological field pocket may determine its phenomenology – specifically, the field’s topological defects might establish the boundary conditions.
  • 5-MeO-DMT and Topological Simplification: 5-MeO-DMT experiences demonstrate phenomenological topological simplification as documented by Cube Flipper and other HEART members.
  • Coupling Kernels and Field Topology: Coupling kernels applied to electric oscillators can modulate field topology (observable in the vortices and anti-vortices of the magnetic field containing the electric oscillators, which you can see in the simulations below).
  • DMT vs 5-MeO-DMT Effects: This framework offers an explanation for the characteristic effects of DMT and 5-MeO-DMT: DMT generates competing coherence clusters and multiple simultaneous observer perspectives – interpretable as topological complexification within the pocket. Conversely, 5-MeO-DMT induces simplification where boundaries mutually cancel, ultimately producing experiences characterized by a single large pinwheel and the dissolution of topological defects (as in cessation states).
  • Paths and Experience: The Path Integral of Perspectives – The final theoretical component suggests that the subjective experience of a topological pocket emerges from “the superposition of all possible paths” within it. The topological simplicity of 5-MeO-DMT states may generate an “all things at once” quality due to the absence of internal boundaries constraining the state. In contrast, DMT’s complex internal topology results in each topological defect functioning as an observer, creating the sensation of multiple entities.

We’re currently developing empirical paradigms to test these frameworks, including psychophysics studies and simulations of brain activity to reconstruct behavior observed through neuroimaging. These ideas are fresh and need a lot of work to be validated and integrated into mainstream science, but we see a path forward and we’re excited to get there.

Now let’s dive into these components and explain them more fully:

0. What’s a Coupling Kernel?

The core concept vis-à-vis QRI was introduced in Cessation states: Computer simulations, phenomenological assessments, and EMF theories (Percy, Gómez-Emilsson, & Fakhri, 2024), where we provided a novel conceptual framework to make sense of meditative cessations (i.e. brief moments at high levels of concentration where “everything disappears”). Coupling kernels was part of the conceptual machinery that allowed us to propose a model for cessations, but it is worth mentioning that it stands on its own as a neat tool that bridges low-level connectivity and high-level resonance in systems of coupled oscillators. The core concept is: in a system of coupled oscillators with a distance function for each pair of oscillators, a coupling kernel is a set of parameters that tells you what the coupling coefficient should be as a function of this distance. I independently arrived at this idea (which others have explored in the past to an extent) during the Canada HEART retreat in order to explain a wide range of phenomenological observations derived from meditative and psychedelic states of consciousness. In particular, we wanted to have a simple algorithmic reduction to be able to explain the divergent effects of DMT and 5-MeO-DMT: the former seems to trigger “competing clusters of coherence” in sensory fields, whereas the latter seems to pull the entire system to a state of global coherence (in a dose-dependent way). Thinking of systems of coupled oscillators, I hypothesized that perhaps DMT induces a sort of alternative coupling kernel (where immediate neighbors want to be as different as possible from each other, whereas neighbors a little further apart want to be similar) while 5-MeO-DMT might instantiate a general “positive kernel” where oscillators all want to be in phase regardless of relative distance. We are in the process of developing empirical paradigms to validate this framework, so please take this with a grain of salt; the paradigm is currently in early developmental stages, but it is nonetheless worth sharing for the reasons I mentioned already (bringing collaborators up to speed and getting the community to start thinking in this new way).

As demonstrated in our work “Towards Computational Simulations of Cessation“, see how a flat “coupling kernel” triggers a global attractor of coherence across the entire system, whereas an alternating negative-positive (Mexican hat-like) kernel produces competing clusters of coherence. This is just a very high-level and abstract demonstration of a change in the dynamic behavior of coupled oscillators by applying a coupling kernel. What we then must do is to see how such a change would impact different systems in the organism as a whole.
Source

It is worth mentioning that in all of our simulations we also add a “small world” lever. The way this one is constructed is as follows: at the start of the simulation, for each oscillator we select two other oscillators at random and wire them to it. The lever controls the coupling constant between each oscillator and the two randomly chosen oscillators assigned to it. In graph theory, this kind of network architecture is often called a “small-world network” because the diameter of the graph quickly collapses as you add more random connections (and in our case, the system synchronizes as you add a positive coupling constant in for these connections). In practice, while the distance-based coupling kernel tunes into resonant modes (traveling waves, checkerboard patterns, etc. as we will see below), the small-world coupling constant adds a kind of geometric noise (when negative) and a global phase to which all oscillators can easily synchronize to (when positive). In effect, we suspect that small-world network-like neural wiring might be responsible for things like dysphoric seizures (due to high level of synchrony coupled with geometric irregularity causing intense dissonance) and disruption of consonant traveling waves (e.g. as a way to modulate anxiety). The phenomenology of being hungover or of experiencing benzo withdrawal might have something to do with an overactive negative small world network coupling constant.

1. Coupling Kernels as Neural-Global Bridge

One of the early simulations that I coded would analyze in real time the Discrete Cosine Transform that the effect of coupling kernels have on a 2D system of oscillators. Intuitively, I knew that the shape of the kernel clearly selected for specific resonant modes of the entire system, but seeing in real time how robust this effect was made me think there probably was a deep mathematical reason behind it. Indeed, as you can see in the below animations, the kernel shape can select checkerboard patterns, traveling waves, and even large pinwheels, all of which have characteristic spatial frequencies that are easily noted in the DCT of the plate of oscillators.

The animations above show: coupling kernel for a 2D system of coupled oscillators, shown on the top-left quadrant. Top-right quadrant is the Discrete Cosine Transform of the 2D plate of oscillators. Bottom-left is a temporal low-pass filter on the DCT. Bottom-right is a temporal high-pass filter on the DCT. Source: Internal QRI tool (public release forthcoming)

In November of last year at a QRI work retreat we stumbled upon two key frameworks that directly address these concepts in the research of Marco Aqil. Namely, CHAOSS (Connectome-Harmonic Analysis Of Spatiotemporal Spectra) and Divisive Normalization. In those works we find how the coupling kernel serves as the critical bridge between local neural activity and global brain-wide behavior. This connection emerges from deep mathematical principles explored in the CHAOSS framework. As we scale up from individual neural circuits to larger networks, the distribution of power across different harmonics of the system becomes accessible through modulation of the coupling kernel. CHAOSS reveals how the eigenmodes (in this case corresponding to “connectome harmonics”) of our structural wiring give rise to global patterns of brain activity. When provided appropriate coupling parameters, neural systems resonate with specific structural frequencies, producing macroscopic standing waves that unify and reorganize local activation patterns.

The link between molecular mechanisms and coupling kernels becomes particularly clear through divisive normalization. This canonical neural computation principle describes how a neuron’s response to input is modulated by the activity of surrounding neurons through specific molecular pathways. Different receptor systems (like 5-HT2A and 5-HT1A) can alter these normalization circuits in characteristic ways (perhaps ultimately explaining the implementation-level effects discussed in Serotonin and brain function: a tale of two receptors (2017, Carhart-Harris, Nutt)). When we map this to our coupling kernel framework, we see that changes in divisive normalization directly translate to changes in the coupling kernel’s shape. For instance, 5-HT2A activation might enhance local inhibition while simultaneously strengthening medium-range excitation, creating the alternating positive-negative coupling pattern characteristic of DMT states. Conversely, 5-HT1A activation might promote more uniform positive coupling across distances, explaining 5-MeO-DMT’s tendency toward global coherence. This provides a concrete mechanistic bridge from receptor activation to field topology: receptor binding → altered divisive normalization → modified coupling kernel → changed field topology. It’s a beautiful example of how a relatively simple molecular change can propagate through multiple scales to create profound alterations in consciousness.

In the CHAOSS framework, each brain region and pathway is represented as a node and edge on a distance-weighted graph. The framework applies spatiotemporal graph filters that act as coupling kernels, encoding how each node influences and is influenced by its neighbors across multiple time scales. By systematically adjusting parameters for excitatory and inhibitory interactions, we can effectively “scan” the connectome’s harmonic space: certain configurations produce stable resonance, others generate traveling waves or chaotic patterns, and some configurations may induce boundary-dissolving states that might prevent the formation of gestalts, and so on. The point being that it can be rigorously shown that in a system of coupled oscillators, a spatial (or temporal) coupling kernel can effectively “tune into” global resonant modes of the entire system.

At the very lowest-level, Marco’s work on Divisive Normalization suggests that there is a mode of canonical neural computation, where the response from a population of neurons to a given input signal is mediated by the surrounding context, a circuit that involves neurons that respond to different neurotransmitter systems. In particular, here we have a bridge that links the very low-level neural circuits to the coupling kernels, which in turn excites specific harmonic resonant modes of the entire system. In other words, the coupling kernel is a sort of intermediate “meso-level” structure that provides system-wide dynamic control of resonance and can be derived as a function of the balance between different neuronal populations that respond to specific neurotransmitters (learn more).

The result of encountering this research is that we now have a crisp conceptual explanation for how coupling kernels might arise (and be controlled by) low-level circuitry, and also why (in a mathematically rigorous way) such kernels can tune into global resonant modes. It therefore starts to look like there is a potentially highly rigorous link between the insights that come from QRI’s Think Tank “taking phenomenology seriously” approach and the current leading academic theories of how drugs affect perception.

2. Geometric Constraints on Coupling Effects

With the above said, the human organism is really complex, and so it is natural to ask: where exactly does the coupling kernel apply to? As argued recently we propose that it would be highly parsimonious if the coupling kernel applied to a range of systems at the same time: the visual cortex, the auditory cortex, the somatosensory cortex, the peripheral nervous system, and even the vasculature. Here the conceptual framework would say that a given drug might change the way low-level circuitry results in divisive normalization with specific constants, and that this change is applied to a wide range of systems. When you take LSD you get a characteristic “vibrational pattern” that might be present in, say, both the vascular system and the visual cortex at the same time. The underlying change is very simple, but the resulting effect is system-dependent due to the characteristic geometry and topology of each subsystem that is affected.

I think that a key insight we ought to work with is that the geometry of the system on which a coupling kernel operates fundamentally determines its high-level effects. A particularly striking example of how geometry shapes coupling kernel effects can be seen in the contrast between the visual cortex and the vasculature system. The visual cortex, organized as a hierarchical geometric network with distinct layers and columnar organization, responds to coupling kernels in ways that reflect its structural hierarchy. When a DMT-like kernel (alternating positive-negative coupling constants) is applied, it generates competing clusters of coherence at different scales of the hierarchy. This manifests phenomenologically as the characteristic layered, fractal-like visual patterns reported in DMT experiences, where similar motifs appear nested at multiple scales. In contrast, a 5-MeO-DMT-like kernel (uniformly positive coupling) drives the hierarchical network toward global synchronization, potentially contributing to the reported dissolution of visual structure in 5-MeO-DMT experiences.

Simulation comparing coupling kernels across a hierarchical network of feature-selective layers (16×16 to 2×2), showing how different coupling coefficients between and within layers affect pattern formation. The DMT-like kernel (-1.0 near-neighbor coupling) generates competing checkerboard patterns at multiple spatial frequencies, while the 5-MeO-DMT-like kernel (positive coupling coefficients) drives convergence toward larger coherent patches. These distinct coupling dynamics mirror how these compounds might modulate hierarchical neural architectures like the visual cortex.
Source: Internal QRI tool (public release forthcoming)

The vasculature system, on the other hand, exemplifies a scale-free network with its branching architecture. Here, the same coupling kernels produce markedly different effects. In the vasculature, a DMT-like kernel would tend to create competing clusters of coherence primarily at bifurcation points, where vessels branch. This could explain some of the characteristic bodily sensations reported during DMT experiences, such as the feeling of energy concentrating at specific points in the body. When a 5-MeO-DMT-like kernel is applied to this scale-free network, it drives the entire system toward global phase synchronization, potentially contributing to the reports of profound bodily dissolution and unity experiences (cf. when you experience a dysphoric 5-MeO-DMT response oftentimes this can be traced to a mostly coherent but slightly off pattern of flow, where “energy” strongly aggregates in a specific point, cf. Arataki’s Guide to 5-MeO-DMT).

Simulation comparing different coupling kernels (DMT-like vs 5-MeO-DMT-like) applied to a 1.5D fractal branching network, showing how modified coupling parameters affect phase coherence and signal propagation. The DMT-like kernel produces competing clusters of coherence at bifurcation points, while the 5-MeO-DMT kernel drives the system toward global phase synchronization – patterns that could explain how these compounds differently affect branching biological systems like the vasculature or peripheral nervous system.
Source: Internal QRI tool (public release forthcoming)

This framework helps explain how a single pharmacological intervention, by modifying coupling kernels through changes in divisive normalization, can produce such diverse phenomenological effects across different biological systems. The geometry of each system acts as a filter, transforming the same basic change in coupling parameters into system-specific resonant patterns. This provides a unified explanation for how psychedelics can simultaneously affect visual perception, bodily sensation, and cognitive processes, while maintaining characteristic differences between compounds based on their specific coupling kernel signatures.

The notion of a continuous graph-based system dissolves traditional distinctions between regional oscillator networks and global wave phenomena into a single multifaceted gem of coupled states. By shaping coupling kernels, we effectively tune into specific connectome harmonics, instantiating global resonant modes that underlie everything from coherent sensory integration to altered states of consciousness.

3. Network Geometry Interactions and Projective Intelligence

A fundamental computational principle emerges from the interaction between networks of different geometries and topologies. This principle underlies what we might call “projective intelligence” or more broadly, mapping/functional intelligence. The interaction between the 2D visual field and 3D somatic field provides a prime example of this principle in action.

Consider how we understand a complex three-dimensional object like a teapot. Our visual system receives a 2D projection, but we comprehend the object’s full 3D structure through an intricate dance between visual and somatic representations. As we observe the teapot from different angles, our visual system detects various symmetries and patterns in the 2D projections: perhaps the circular rim of the spout, the elliptical body, the handle’s curve. These 2D patterns, processed through the visual cortex’s hierarchical geometric network, generate characteristic resonant modes. Simultaneously, our somatic system maintains a 3D spatial representation where we can “map” these detected symmetries. The brain effectively “paints” the symmetries found in the 2D visual field onto the 3D somatic representation, creating a rich multi-modal representation of the object.

This process involves multiple parallel mappings between sensory fields, each governed by its own coupling kernel. The visual field might have one kernel that helps identify continuous contours, while another kernel in the somatic field maintains spatial relationships. These kernels can synchronize or “meet in resonance” when the mappings between fields align correctly, giving rise to stable multimodal representations. When we grasp the teapot, for instance, the tactile feedback generates somatic resonant modes that match our visually-derived expectations, reinforcing our understanding of the object’s structure (many thanks to Wystan, Roger, Cube Flipper, and Arataki for many discussions on this topic and their original contributions thereof – the fact that visual sensations devoid of somatic coupling have a very different quality in particular was a brilliant observation by Roger that fomented a lot of insights in our sphere).

The necessity of interfacing between spaces of different dimensionality (e.g. 3D somatic space and 2.5D visual space) creates interesting constraints. In systems exhibiting resonant modes emergent from coupled oscillator wiring, energy minimization occurs precisely where waves achieve low-energy configurations in both interfacing spaces simultaneously. This requires finding both an optimal projection between spaces and appropriate coupling kernels that allow the resulting space to behave as if it were unified.

Remarkably, this framework suggests that our cognitive ability to understand complex objects and spaces emerges from the brain’s capacity to maintain multiple concurrent mappings between sensory fields of different dimensionalities. Each mapping can be thought of as a kind of “cross-modal resonance bridge,” where coupling kernels in different sensory domains synchronize to create stable, coherent representations. When this level of coherence is achieved, the waves cannot detect the underlying projective dynamic: there simply is no “internal distinction” to be found in an otherwise complex system that typically maintains many differences between the spaces it maps. At the limit, the perfect alignment between the various mappings and coupling kernels of all sensory fields is what we hypothesize explains meditative cessations.

This multiple-mapping approach might explain phenomena like the McGurk effect, where visual and auditory information integrate to create a unified perception, or the rubber hand illusion, where visual and tactile fields can be realigned to incorporate external objects into our body schema. In each case, coupling kernels in different sensory domains synchronize to create new stable configurations that bridge dimensional and modal gaps.

The framework also provides insight into how psychedelics might affect these cross-modal mappings. DMT, for instance, might introduce competing clusters of coherence across different sensory domains, leading to novel and sometimes conflicting cross-modal associations. In contrast, 5-MeO-DMT might drive all mappings toward global synchronization, along which characteristic system-wide synchronization effects manifest, potentially explaining the reported dissolution of distinctions between sensory modalities and the experience of unified consciousness.

Understanding consciousness as a system of interacting dimensionally-distinct fields, each with their own coupling kernels that can synchronize and resonate with each other, offers a powerful new way to think about both ordinary perception and altered states. It suggests that our rich experiential world emerges from the brain’s ability to maintain and synchronize multiple parallel mappings between sensory domains of different dimensionalities, creating a unified experience from fundamentally distinct representational spaces.

4. Topological Solution to the Boundary Problem

Here’s where the framework really starts to come together: if we identify fields of physics with fields of qualia (a field-based version of panpsychism), then the boundaries between subjects could be topological in nature. Specifically, where magnetic field lines “loop around” to form closed pockets, we might find individual moments of experience. These pockets aren’t arbitrary or observer-dependent: they’re ontologically real features of the electromagnetic field that naturally segment conscious experience (note: I will leave aside for the time being the discussion about the ontological reality of the EM field, but suffice to say that even if the EM field is an abstraction atop the more fundamental ontology of reality, we believe topological segmentation could then apply to that deeper reality).

This provides a compelling solution to the boundary problem: what stops phenomenal binding from expanding indefinitely? The answer lies in the topology of the field itself. When field lines close into loops, they create genuine physical boundaries that can persist and evolve as unified wholes. These boundaries are frame-invariant (preserving properties under coordinate transformations), support weak emergence without requiring strong emergence, and explain how conscious systems can exert downward causation on their constituent parts through resonance effects.

5. Electromagnetic Field Topology and its Modulation

To demonstrate how coupling kernels create and control these field boundaries, we’ve developed three key simulations showing electric oscillators embedded in magnetic fields. By visualizing the resulting field configurations across different geometries – 2D grids, circular arrangements, and branching structures – we can directly observe how coupling kernels shape field topology.

When we apply a DMT-like kernel (alternating positive-negative coupling constants at different distances), we see an explosion of topological complexity in which multiple vortices and anti-vortices emerge, creating a diverse patterns of nested field structures. The same kernel creates characteristic patterns in each geometry, but always tends toward complexification. In contrast, applying a 5-MeO-DMT-like kernel (uniformly positive coupling) causes these complex structures to simplify dramatically, often collapsing into a single large vortex or even completely smooth field lines.

Coupled oscillators in a 2D space whose phase is interpreted as electric oscillations are embeded in a magnetic field whose topology becomes mediated by the coupling kernel. Source: Internal QRI tool (public release forthcoming)

[Note: These are still 2D simulations – a full 3D electromagnetic simulation is in development and will likely reveal even richer topological dynamics. However, even these simplified models provide striking evidence for how coupling kernels can control field topology.]

6. 5-MeO-DMT and Topological Simplification

The remarkable alignment between our theoretical predictions and actual psychedelic experiences becomes clear when we examine 5-MeO-DMT states. As documented in Cube Flipper’s “5-MeO-DMT: A Crash Course in Phenomenal Field Topology” (2024), these experiences frequently involve the systematic disentangling or annihilation of local field perturbations (“topological defects”) over time. Subjects report a progressive dissolution of boundaries and eventual sense of absolute unity or “oneness.” Significantly, recent EEG analysis of 5-MeO-DMT experiences also reveal remarkable topological properties, which we’re currently trying to derive from a 3D model of the brain in light of altered coupled kernels.

Source: Cube Flipper’s HEART essay on 5-MeO-DMT and field topology.

This phenomenology maps really well onto what our electromagnetic simulations predict: a 5-MeO-DMT-like coupling kernel transforms networks of swirling singularities into simplified field configurations. The effect isn’t limited to any particular neural subsystem: it appears to drive global topological simplification across multiple scales and geometries, explaining both the intensity and the consistency of the experience across subjects. In turn, a lot of the characteristic phenomenological features of 5-MeO-DMT might find their core generator as the interaction between a very positive coupling kernel and the interesting relationships between different sensory fields as they try to map onto each other to minimize dissonance. At the peak of a breakthrough experience, typically this culminates in what appears as a global multimodal coherent state, where presumably all the sensory fields have found a mapping to each other such that the waves in each look exactly the same: the recipe for a zero informational state of consciousness. A whiteout.

What’s particularly fascinating is that this framework suggests normal waking consciousness might represent a sweet spot of topological complexity. It carries enough structure to maintain a stable sense of self and world, but not so little as to dissolve completely (as in 5-MeO-DMT states). Each topological defect could be thought of as a kind of “perspectival anchor” in the field. As these defects systematically dissolve under 5-MeO-DMT, we would expect exactly what subjects report: a progressive loss of distinct perspectives culminating in a state of pure unity. Perhaps sleep and dreaming could be also interpreted through this lens: during periods of wakefulness we slowly but surely accumulate topological defects; sleep and dreaming might be a process of topological simplification where the topological defects aggregate and cancel out. Notice next time you find yourself in a hypnagogic state how it feels like to “let go of the central grasping to experience” and the subsequent fast “unraveling” of the field of experience. Much more to say about this in the future (a topological simplification theory of sleep).

7. Coupling Kernels and Field Topology

The mechanism by which coupling kernels control field topology reveals something really deep, abstract, and yet applied about consciousness: the same mathematical object (the coupling kernel) can simultaneously modulate both neural dynamics and electromagnetic field structure. This isn’t just correlation: we are talking about a direct causal chain from molecular interaction to conscious experience and back. Precisely the sort of structure we want in order to both ground the topological boundary problem solution in neurophysiology and avoid epiphenomenalism (since the field topology feeds back into neural activity, cf. local field potentials).

Consider how this works: when we apply a coupling kernel to a network of electric oscillators, we’re not just changing their relative phases. We’re also sculpting the magnetic field they generate. Each oscillator contributes to the local magnetic field, and the coupling kernel determines how these contributions interfere. Positive coupling between nearby oscillators tends to align their fields, creating smooth, continuous field lines. Negative coupling creates discontinuities and vortices. The resulting field topology emerges from these collective interactions, yet acts back on the system as a unified whole through electromagnetic induction.

What’s particularly elegant about this mechanism is its scale-invariance. Whether we’re looking at ion channels in a single neuron or large-scale brain networks, the same principles apply. The coupling kernel acts as a kind of “field-shaping operator” that can be applied at any scale where electromagnetic interactions matter. This helps explain why psychedelics, which presumably modify coupling kernels through receptor activation, can have such profound and coherent effects across multiple levels of brain organization.

8. DMT vs 5-MeO-DMT Effects

With this mechanism in hand, we can now understand the radically different effects of DMT and 5-MeO-DMT in a new light. The key insight is that these compounds don’t just change what we experience. They transform the very structure of the field that gives rise to bound experiences.

DMT appears to implement a coupling kernel with a characteristic Mexican-hat profile: strong negative coupling at short distances combined with positive coupling at medium distances. When applied to neural networks, this creates competing clusters of coherence. But more fundamentally, it generates a field topology rich in stable vortices and anti-vortices. Each of these topological features acts as a semi-independent center of field organization – a kind of local “observer” within the larger field.

This helps explain one of the most striking aspects of DMT experiences: the encounter with apparently autonomous entities or beings. If each major topological defect in the field functions as a distinct locus of observation, then the DMT state literally creates multiple valid perspectives within the same field of consciousness. The geometric patterns commonly reported might reflect the larger-scale organization of these topological features – the way they naturally arrange themselves in space according to electromagnetic field dynamics.

The bizarre yet consistent nature of DMT entity encounters takes on new meaning in this framework. These entities often seem to exist in spaces with impossible geometries, yet interact with each other and the observer in systematic ways. This is exactly what we’d expect if they represent stable topological features in a complexified electromagnetic field: they would follow precise mathematical rules while potentially violating our usual intuitions about space and perspective. Even our notion of a central observer and object of observation; the DMT space has many overlapping “points of view” derived from the complex topology of the field.

These insights stand in stark contrast to 5-MeO-DMT’s effects, but they emerge from the same underlying mechanism. They also suggest new research directions. For instance, we might be able to predict specific patterns of field organization under different compounds by analyzing their receptor binding profiles in terms of their implied coupling kernels. This could eventually allow us to engineer specific consciousness-altering effects by designing molecules (or drug cocktails) that implement particular coupling kernel shapes.

9. Paths and Experience: The Path Integral of Perspectives

Here’s where we get to be both mathematically precise and delightfully speculative: I propose that the mapping between field topology and phenomenology is best understood through the path integral of all possible perspectives within a topological pocket. This isn’t just mathematical fancy – it’s a necessary move once we realize that consciousness doesn’t always have a center.

Think about it: we’re used to consciousness having a kind of “screen” quality, where everything is presented to a singular point of view. But this is just one possible configuration(!). On DMT, for instance, experiencers often report accessing topological extrema instantaneously, as if consciousness could compress or tunnel through its own geometry to find patterns and symmetries. This suggests our usual centered experience might be more of a special case – perhaps we’re too attached (literally, in terms of field topology) to a central vortex that geometrizes experience in a familiar way.

When we consider the full range of possible field topologies, things get wonderfully weird (but also kind of eerie to be honest). The “screen of consciousness” starts looking like just one possible way to organize the field, corresponding to a particular kind of stable vortex configuration. But there are so many other possibilities! The path integral approach lets us understand how a completely “centerless” state could still be conscious – it’s just integrating over all possible perspectives simultaneously, without privileging any particular viewpoint.

This framework helps explain why 5-MeO-DMT can produce states of “pure consciousness” without content – when the field topology simplifies enough, the path integral becomes trivial. There’s literally nothing to distinguish one perspective from another. In a perfectly symmetrical manifold, all points of view are exactly the same. This ultimately ties in to the powerful valence effects of 5-MeO-DMT, seen through the lens of a field-theoretic version of the Symmetry Theory of Valence (Johnson 2016). We’re currently developing valence functions for field topologies, though we don’t yet have concrete results worth showing (but writeup about it forthcoming). Conversely, if this framework is accurate, then DMT’s complex topology creates many local extrema, each serving as a kind of perspectival anchor point, leading to the sensation of multiple observers or entities. This would be predicted to have generically highly mixed valence, with at times highly dissonant states and at times highly consonant states, yet always rich in internal divisions and complex symmetries rather than the “point of view collapse” characteristic of 5-MeO-DMT.

Our electromagnetic field visualizations make this particularly concrete. When we observe the magnetic field configurations in our simulations, we’re essentially seeing snapshots of the space over which these path integrals are computed. In the DMT-like states, the field is rich with vortices and anti-vortices – each one representing a potential perspective from which to “view” the field. The path integral must account for all possible paths through this complex topology, including paths that connect different vortices. This creates a kind of “quantum tunneling of perspective” (I know how this sounds, but bear with me) where consciousness can leap between different viewpoints, perhaps explaining the characteristically bizarre spatial experiences reported on DMT. In contrast, when we apply the 5-MeO-DMT-like kernel, we watch these vortices collapse and merge. The topology simplifies until there’s just one global structure – or sometimes none at all. At this point, the path integral becomes trivial because all paths through the field are essentially equivalent. There’s no longer any meaningful distinction between different perspectives because the field has achieved a kind of perfect symmetry.

Conclusion: A Network of Insights

This theoretical framework – connecting coupling kernels, field topology, and conscious experience – emerged from years of collaborative work and inspiration. While the specific insights about coupling kernels and their effects on field topology are my contributions, they stand atop a mountain of brilliant work by the extended QRI family.

I’m deeply grateful to Chris Percy for his rigorous development of these ideas, particularly in understanding their philosophical implications in the context of the current literature of consciousness studies, Michael Johnson for years of fruitful collaboration (and his great contribution to the field via the Symmetry Theory of Valence and formalization of Neural Annealing), as well as really helpful QRI advisors like Shamil Chandaria, Robin Carhart-Harris, and Luca Turin. Also special thanks to the great long-time doers in QRI like Hunter Meyer, Marcin Kowrygo, Margareta Wassinge and Anders Amelin (RIP). Cube Flipper’s phenomenological investigations of 5-MeO-DMT have been invaluable, as have the insights from Roger Thisdell, Wystan Bryan-Scott, Asher Arataki, and others. Everyone on the HEART team’s dedication to careful exploration has provided crucial empirical grounding for these theoretical developments.

I’m also excited about ongoing work with our academic collaborators (to be announced soon – we’re currently designing studies to test these ideas rigorously). In particular I want to thank Till Holzapfel for his awesome research and collaborations (and help with the QRI Amsterdam meetup!), Taru Hirvonen for her visual intuitions and work, Emil Hall for his amazing programming and conceptual development help, Symmetric Vision for his incredible visual work and intuitions, Ethan Kuntz for his insights on spectral graph theory, Scry for his retreat replications, and Marco Aqil for his ground-breaking research (and for giving a presentation at the recent Amsterdam meetup), and many more people who have recently been delightful and helpful for the mission (special shoutout to Alfredo Parra). This emerging research program promises to put these theoretical insights to empirical test, and we’re working at a team to bridge phenomenology and hard neuroscience. It’s happening! 🙂

Also, none of this would have been possible without the broader QRI community and its supporters – a group of fearless consciousness researchers willing to take both mathematical rigor and subjective experience seriously. Together, we’re building a new science of consciousness that respects both the precision of physics and the richness of lived experience.

The path ahead is clear (well, at least in my head): we need to develop more sophisticated simulations of field topology, particularly in three dimensions, and devise clever ways to test these ideas experimentally through psychophysics and microphenomenology. The coupling kernel paradigm offers a concrete mathematical handle on consciousness – one that might let us not just understand but eventually engineer specific states of consciousness. It’s an exciting time to be working on this hard problem!

Thanks for coming along on this wild ride through field topology, psychedelic states, and the mathematics of consciousness. Stay tuned – there’s much more to come!

– Andrés 🙂