Healing Trauma with Neural Annealing

The folks at QRI have recently given a string of presentations. Before I jump to the main topic of this article, I will briefly mention a few of these presentations that are likely to be of interest to the reader. Quintin Frerichs recently presented about Neural Annealing at the Wellcome Center for Human Neuroimaging at UCL. I recently presented about Mapping the Heaven Realms at the SSC/ACX online meetup organized by Joshua Fox. Also, a few weeks ago I participated in the U.S. Transhumanist Party Virtual Enlightenment Salon (the live conversation was so engaging we ended up talking for four hours). And finally, as the main topic of this article, the talk I gave at the Oxford Psychedelic Society on May 6th, 2021:

Healing Trauma with Neural Annealing: Is Annealing the Key Condition for Successful Psychedelic Psychotherapy?

Abstract of the Talk:

Mystical-type experiences mediate the therapeutic benefit of psychedelic-assisted psychotherapy (Griffiths, 2016; Ross, 2016; Yaden, 2020). In this talk we will explore why this may be the case and how we might improve this effect. On the one hand we can interpret the effect of mystical-type experiences through the lens of belief and attitude change (Carhart-Harris and K. J. Friston, 2019). But beliefs that are not deeply felt are unlikely to have much of an effect. Why would mystical-type experiences in particular cause deeply felt belief changes? On the other hand, one can interpret the effect of these experiences to be healing at a low-level: they allow the reconfiguration of the microstructure of our experience in beneficial ways. The first lens suggests that these experiences change what we believe and think about, whereas the second lens suggests that the experiences change how we feel. In this talk we will unify these two lenses and argue that neural annealing (Johnson, 2019) underlies high-level changes in beliefs and attitudes as well as low-level microstructural healing of internal representations. This paradigm ties together the puzzling effects of mystical-type experiences by interpreting them as uniquely strong versions of neural annealing. We suggest that traumatic memories are indeed implemented with low-level microstructural dissonance in the internal representations (Gomez-Emilsson, 2017). Not only are they about something bad, they also feel bad. In turn, neural annealing targeted towards these internal representations can heal and transform them from dissonance-producing to consonance-producing. More so, neural annealing also enhances the information propagation fidelity of the nervous system, allowing the healed representations to update the state of the rest of the nervous system. This insight, along with careful study of annealing dynamics under psychedelics, can allow us to target the annealing process in order to heal these internal representations more effectively. We conclude with empirical predictions for what to look for in order to identify the signatures of successful neural annealing under psychedelics and suggest methods to piggyback on the natural well-trodden paths of beneficial annealing (e.g. meditation, yoga, music, creativity) to optimize such experiences.


Why This Is Important

There are two main reasons I think sharing this work as soon as possible with the world is very beneficial. The first is that it genuinely advances a new model for how to optimize psychedelic therapy. In particular, I think that being aware of this model can be very useful for people who intend to self-medicate with psychedelics. Although there is a vast literature for psychedelic psychotherapy, it is largely laced with metaphysical views, implicit background philosophical assumptions incompatible with science, and in my view, questionable ethics.

The second point is that this model can be used as an antidote to psychedelic brainwashing. If a friend of yours has been taking a lot of psychedelics (with or without a shaman) and now has a web of unfalsifiable beliefs that do not seem to help them, this presentation might work to help them understand what is going on in their mind. Additionally, once you understand how psychedelic annealing works, you can anticipate irrational belief changes based on the texture of the experience and proactively prevent them. Indeed, being showered with bliss consciousness by a DMT entity might be healing to your nervous system, but alas, it also anneals in you a conviction in the independent existence of such entities. With this presentation, the hope is that you can keep the healing while discarding the irrational beliefs (because you will now be able to see how they are implemented!). If we want to indeed create a truth-seeking psychonaut shanga (aka. a Super-Shulgin Academy) we *have to* have an adequate model of how exotic states of consciousness modify one’s belief networks. The penalty of not modeling this accurately leads to the loss of one’s critical faculties. I have seen it happen (see Appendix A & B), and I am not impressed. We can do better.

Without further ado, here is the video:

And here are the slides (with some light comments along the way on the topics that have not been previously discussed):


Many thanks to the Oxford Psychedelic Society for the invitation to give this talk. 🙂

Model (1) has the problem that the researchers themselves are not exposed to the exotic states of consciousness, and as such, what they write and theorize about comes from second-hand accounts. More so, the bulk of the direct phenomenological information the participants gain access to is generally discarded as it goes through the low-dimensional information filters of standardized questionnaires. There is no real buildup of phenomenological information or an effort to integrate it across participants (participants don’t generally talk to each other). The model does excel at generating copious high-quality neuroimaging data.

Model (2) suffers from the problem that the idiosyncratic beliefs of the psychonaut tend to “anneal more deeply” (see the next slide for a more through description of this) with each trip. Unless they were to focus on the phenomenal character of the experience rather than the intentional content, what tends to happen is that specific high-level beliefs become energy sinks and they dominate the exploration. Recall how DMT’s world-sheet “crystallizes” around objects and ideas you can recognize. Thus, as you take psychedelics over and over, the realms of experience one goes to will tend to follow recurring themes along the lines of what the most successful energy sinks from previous experiences have been. The explorer usually does not develop technical models of the phenomenological effects, but rather, tends to focus on the metaphysical or philosophical implications of the experiences.

Model (3) is like that of a think tank. Ever since writing articles like How to Secretly Communicate with People on LSD, we have received a lot of correspondence from pretty smart people who enjoy exploring exotic states of consciousness. The multi-year dialogue between us and them and each other has resulted in a lot of generative model building for which we can then get feedback. Grounded in common background philosophical assumptions and a drive towards phenomenological accuracy, the type of output of this model tends to look much more like The Hyperbolic Geometry of DMT Experiences than either a neuroscience paper (model 1) or a book about the Earth Coincidence Control Office (model 2).

Which of these information-processing architectures would you use if you were trying to figure out the truth of how psychedelics work? If they were diagrams for a neural network architecture, which one do you think would model and integrate information most effectively? Ultimately, we should think of these models as complementary. But since model 3 is novel and largely unexplored, it might be sensible to pay attention to what it outputs.

(H/T Quintin Frerichs for this slide)

This slides illustrates the sort of topics and problems that a “Good Annealing Manual” would need to cover. As an integrated “energy management” strategy, such a manual would describe how to raise energy, how to dampen it, how to translate it from one domain into another, how to stabilize a state, how to get knocked out of an unhelpful limit cycle, and so on.

(H/T Quintin Frerichs for this slide)

Note: I should have cited Michael Schartner’s work (and more generally the work coming out of Anil Seth‘s lab which applies the predictive processing paradigm and neural network feature visualization to model the effects of psychedelics). Apologies for this omission. Importantly, all of that work (in addition to REBUS and SEBUS) lives at the computational level of analysis. What QRI is bringing into the picture is how the implementation level based on principles of harmonic resonance and the Symmetry Theory of Valence underlie predictive processing. More on this below.

One of the interesting ideas of Steven Lehar is applying the duality between standing wave patterns and resonant modes of objects to the brain. A lot of psychedelic phenomenology suggests that there is a duality between the vibe of the state and the geometric layout of the multi-modal hallucinations. In other words, each phenomenal object has a corresponding way of vibrating, and this is experienced as a holistic signature of such objects. (cf. Resonance and vibration of [phenomenal] objects). (See also: Hearing the shape of a drum).

In the context of this presentation, the most important idea of this slide is that the duality between standing wave patterns and the vibe of the experience showcases how symmetry and valence are related. Blissful “heavenly realms” on DMT are constructed in ways where the resonance of the phenomenal objects with each other is consonant and their structure is symmetrical. Likewise, the screechy and painful quality of the DMT “hell realms” comes along with asymmetries, discontinuities, and missing components in the phenomenal objects that make up experiences. The overall vibe of the space is the result of the intrinsic vibratory modes of each phenomenal object in addition to each of the possible interactions between them (weighted by their phenomenal distance). An analogy readily comes to mind of an orchestra and the challenges that come with making it sound consonant.

From Mike’s Why we seek out pleasure:

A good algorithmic theory of cognition will collect, unify, and simplify a lot of things that look like odd psychological quirks, and recast them as deeply intertwined with, and naturally arising out of, how our brains process information. I’m optimistic that Symmetry Theory will be able to do just this- e.g.,

* Cognitive dissonance happens when two (or more) patterns in your head are battling for your neural real estate, and they’re incompatible– i.e., they’re collectively dissonant/asymmetrical.

* Denial is what happens when your brain attempts to isolate/quarantine such patterns, and is actively working to prevent this tug-of-war for neurons.

This model implies that your brain can evaluate the “internal consistency/harmony” of a neural pattern, and reject it if there’s a negative result- and also the “simulated relative compatibility/harmony” of two neural patterns, and try to keep them isolated if there’s a negative result. I’d suggest the best way to understand this is in terms of projective geometry, resonance, and symmetry: i.e., to evaluate a pattern’s “internal harmony” and whether it ‘runs well (is stable) on existing hardware’, the brain uses principles of resonance to apply certain geometric projections (high-dimensional-to-lower-dimensional transformations) to the pattern to see if the result is stable (unchanged, or predictably oscillating, or still strongly resonant) under these transforms. Stable patterns are allocated territory; unstable ones (=dangerous neural code) are not. The internal mechanics of this will vary across brain areas (based on the specific resonance profile of each area) and emotional states, which might contribute to how certain types of information tend to end up in certain brain regions. Likewise, this could explain how moods coordinate information processing– by changing the resonance landscape in the brain, thus preferentially selecting for certain classes of patterns over others. A core implication of this model is that different kinds of dissonance will drive different kinds of behavior (feel like different kinds of imperatives), and based on what action is needed, a mood may create (or be the creation of) a certain kind of dissonance.


Why we seek out pleasure: the Symmetry Theory of Homeostatic Regulation, Michael Johnson (2017)

Now applying annealing to the above, we hypothesize that: (1) On the one hand, at the implementation level neural annealing works as a method to reduce dissonance by escaping local minima. (2) On the other hand, at the computational level simulated annealing can be used as a method to reduce prediction errors (cf. message passing and belief propagation). We hypothesize that there is a kind of duality between these two levels of abstraction. We are very interested in cleanly formalizing it so it can be empirically tested. But the facts seem to suggest that there is something here. What this duality says is that for any transformation that you do to the resonance network there will be a corresponding effect on the belief network and vice versa. For example, in this light, you will always find that denial or cognitive dissonance will come along with the phenomenology of “resistance” in one of its many guises (such as muscle tension, feelings of viscosity, or hardness). If you can address the muscle tension directly with progressive relaxation (or yoga, massage, etc.) you will also be implicitly addressing the integration of information into your world-model. At the same time, you may use specific beliefs in order to relax specific muscles, and some aspects of meditation may involve doing this to an extent (e.g. “now is all there is” and “the self is illusory” are beliefs that would seem to result in particular patterns of mental and physical relaxation).

We might succinctly explain how a resonance network trying to minimize dissonance could implement the free energy principle. Namely, we could maximize “accuracy – complexity” in the following way: If complex models require complex networks of resonance to be implemented, then there might be an inherent dissonance cost to complexity. More symmetrical configurations lower this cost, which makes more compact and coherent models preferable. At the same time, to take care of the accuracy, prediction errors themselves might be implemented with dissonance (e.g. via out-of-phase communication between layers of the hierarchy). Together, these two effects favor both accurate and simple models.

An interesting contrast that illustrates this duality between the computational and implementational level of abstraction is that between the effects of DMT and 5-MeO-DMT. Particularly, DMT seems to give rise to the chaotic generation of information and this can be seen in something as simple as the style of the tracer effects it induces (richly-colored flip-flopping between positive and negative afterimages). 5-MeO-DMT’s tracer effects are generally monochromatic and the same color as that of the input. (See: Modeling Psychedelic Tracers with QRI’s Psychophysics Toolkit: The Tracer Replication Tool).

We hypothesize that DMT’s effects at the implementation level can be understood as the result of competing clusters of coherence across the hierarchy, whereas the main attractors of 5-MeO-DMT seem to involve global coherence. Modulating the average synaptic path length in a system of coupled oscillators can give rise to this sort of effect. By randomly adding connections to a network of coupled oscillators one first sees an emergent state of many competing patches of synchrony, and then, after a threshold is crossed, one starts seeing global synchrony emerge. Despite both drugs making the brain “more interconnected”, the slight difference in just how interconnected it makes it, may be the difference between the colorful chaos of DMT and the peaceful nothingness of 5-MeO-DMT.

The competing clusters of coherence across the hierarchy can evolve to adapt to each other. The DMT realm is more of an ecosystem than it is a state per se (ex: Hyperspace Lexicon). And due to the duality between dissonance minimization and prediction error minimization, avoiding updating one’s belief in the direction of these realms being real causes intense cognitive dissonance. Some level of belief updating to fit the content of the hallucinations might be very difficult to resist. Indeed, the forced coherence across the layers of the hierarchy would be bypassing one’s normal ability to resist information coming from the lower layers.

On peak experiences such as those induced by 5-MeO-DMT, global coherence will generally have the effect of dissolving internal boundaries. In turn, due to the duality proposed, belief updating in the direction of extreme simplicity is very difficult to resist. Global annealing without sensorial chaos results in the minimization of model complexity; high accuracy is taken care of thanks to the low information content of the state. As a consequence, one experiences very high-valence, high-energy, high-symmetry states of consciousness that come along with belief updating towards ideas with close to zero information content.

The high-valence nature of the state can be very useful to heal dissonance in the network, so therapeutic benefits seem very promising (notwithstanding the somewhat forced belief updates the state induces).

Unfortunately a nearby attractor of the globally coherent states is when there are two incompatible coherent states competing with one another. This can result in extremely negative valence and belief updating in the direction of “everything being bad”.

We now see how the typical belief changes caused by these two drugs have a dual counterpart in how they feel. I am of the opinion that a commitment towards truth and careful attention to one’s state of mind can prevent (or at least substantially lessen) the epistemological failure modes of these drugs. But since this kind of model is not known by the general population, for most people these drugs do tend to act as “epistemological hand grenades”.

See Appendix A & B at the bottom of this article for examples of each of these failure modes.

Now on to the therapeutic applications: practicing loving-kindness meditation consistently for weeks before a trip seems to substantially change its phenomenal character. It feels that metta practice over time anneals a consonant metronome which can become massively amplified during a psychedelic experience. In turn, a brightly shinning metta metronome emits “healing waves of energy” within one’s world-simulation (I know how crazy this sounds!), which impact the contents of one’s subconscious in ways that reduces their internal dissonance.

Similar benefits can be obtained from other meditation practices, as long as their emphasis is on high-valence and coherent states of mind. See also: Buddhist Annealing (video).

Importantly, you can “work smart” if you manage to use the seeds of consonance as the nucleation sources for alignment cascades. This can heal at a very deep level, and it is what people are talking about when they say things like “all is love”.

A secular Good Annealing Manual would ideally have very detailed information for how to move around in the state-space of consciousness.

Apparently, equanimity is also highly beneficial during psychedelic experiences. But rather than merely repeating the mantras that everyone in the psychedelic community chants (“just let go”, “surrender”, “accept”), we can use a More Dakka approach and aim to maximize equanimity rather than merely invoking it. Taking psilocybin during a meditation retreat in which you do a lot of equanimity exercises will allow you to “let go” with much greater skill than what you could do in normal everyday life. As a result, one is able to “learn one’s lessons” with much greater ease and a lot less resistance. This, I think, is generally good. After all, the point is not to punish oneself, but to learn from one’s mistakes.

In turn, Shinzen Young says that experiencing pleasure with equanimity is very healing. By not grasping, one is letting the consonant waves propagate freely throughout one’s nervous system, which results in positive annealing. So a possible therapeutic modality might be to combine peak states together with high levels of equanimity. If we want to bump the therapeutic effect sizes of psychedelic psychotherapy, this is the sort of thing I consider to be very promising.

I conclude by providing some annealing targets that are generically good for one’s mental health. Practice them consistently before a psychedelic experience so that they can be the nucleation points of sane and hedonically beneficial psychedelic annealing. Being bathed by love is good. Being bathed by love and equanimity at the same time is even better. Being bathed by love and all Seven Factors of Awakening at the same time might be still even better. The ceiling of wholesome happiness is not currently known by science. It is probably much higher than we can imagine.

If you found this talk inspiring, generative, or clarifying for your own work, please cite it! If you want to see more work like this and help us transform the alchemy of consciousness into a chemistry of the mind, please consider donating to QRI. Every dollar takes us closer to being able to empirically test these models and use them to develop technology to alleviate suffering in bulk.

Thank you!!!


Appendix A: What Happens When You Take Too Much DMT – What Does Overfitting Look Like?

  • A case study of a psychiatrist case who self-medicated his depression with a regiment of 1g of DMT (along with MAOIs) and 4mg of clonazepam a day:
    • “On arrival, the patient was nonverbal, combative, and required six security guards to restrain him. When less restrictive measures failed, he was given propofol 1,000 mg IV, ketamine 500 mg IM, midazolam 5 mg IV, diazepam 20 mg IV, and fentanyl 4 mg IV with minimal effect.”
    • “Psychiatry was consulted after the patient’s delirium resolved and he was medically stabilized as he exhibited symptoms of mania and psychosis. He was pressured in his speech, hyperreligious, and delusional. He believed that demons were leeching into his soul and asked the medical staff for an exorcism. It was recommended that the patient be admitted to the behavioral health unit for mood stabilization.”
  • How can I help my friend understand that what he is seeing is a side effect of smoking DMT on a daily basis? (from Quora – note: it is impossible for me to verify the accuracy of this report). From the comment thread:
    • “He has been smoking it every day and night for the past 3 months that I know of. He sees these little beings everywhere and says they are trying to destroy his house pushing it over. He also says they spray mace and fairy dust and little balls in his face and other peoples too. He doesn’t believe that nobody else sees this happening, he says we have all been compromised and can’t be trusted. I’m worried about him and also his girlfriend that has to deal with him and he’s delusional. His daughter is scared to come home, his parents want to have him committed, and he doesn’t believe it has anything to do with dmt! He absolutely believes it is real.”
    • “He is always under the influence of DMT, he smokes it all day every day. He says it no longer makes him hallucinate like when he first tried it, now it just takes away pain . NOT TRUE!! it’s like now he believes that this altered state of mind is reality and he’s losing everything. He is even destroying his own house to get them out from behind the walls.the other night he stood up and started stabbing his ceiling saying he was going to get them. It’s very disturbing to see him like this.”
    • “He’s doing about the same. Last time I went to see him he was showing me how the moon was following him into his back yard and then back to the front yard . He also sees a bunch of drones in the sky that I can’t see. He still doesn’t believe that we can’t see the walls and countertops moving, or feel the fairy dust being sprayed in our faces.”
  • The YouTube channel C.U.E. COMPREHENSIVELY UNCOVERING EVIDENCE seems to exemplify quite accurately what DMT-induced overfitting looks like (e.g. see his DMT-informed numerological musings)
  • Reddit user ClockJoule: see an interview with him about his daily DMT use and the beliefs that he developed as a consequence: Magic Mushroom Cloud – THE MAN WHO SMOKED DMT FOR 120 DAYS STRAIGHT.
  • [Report(s)] A warning to my fellow psychonauts regarding hyperspace entities (wall of text alert!) – excerpt:
    • “It all culminated in one long, elaborate, and highly dramatic visionary experience in which I was essentially ‘recruited,’ initiated in some grand ceremony alongside a large group of others presumably in my same situation (which may have just been “actors” ). It was all part of some kind of vast organization, which could best be described as ‘universal consciousness transcendental cosmic hippie space religion.’ [Read Lehar’s warning against believing what the DMT entities tell you]. It all had a very attractive but vaguely cult-like Scientology kind of feel to it. They even had their own music (which was actually pretty cool; see my comments on “the director” in part 4 for more details), propaganda, regular meetings and rituals, the whole works. They even seemed to revere a deity of some sort, their version of The Source (more detail on that in part 5), but this whole experience was so full of illusion and misdirection that I have no idea what their ‘deity’ really was, nor their true relation to it.”
    • “I’ve gone on way to long already and need to start wrapping things up here, but long story short, in light of their new demands of allegiance, and through a separate series of bizarre synchronicities in ‘real life’ (what that means to me now, I have no idea) that I still can’t quite explain, I began to have some serious doubts and questions that needed answers. As I reflected on all that they had taught me, I began to realize that there were some major gaps in my knowledge, and that I had unwittingly filled in a lot of the blanks with my own speculation while assuming the picture I was being given was much more complete than it actually was. To summarize, over a series of increasingly confrontational and unpleasant experiences, I became less and less satisfied with their vague and evasive answers to my direct (and I think perfectly reasonable) questions, and we had something of a falling out, to put it very mildly. They eventually dropped all pretenses and flat-out turned on me, beginning a long period of harsh punishment.”
    • “The results weren’t pretty. Their facade began to crumble as I saw through more and more of what I now recognized as deceptive illusions. What truly lay behind it was hideous, repulsive, monstrously evil, relentlessly manipulative, filled with petty malicious intent, and not nearly as righteous, enlightened, or omnipotent as they pretended to be. I’m actually still pretty uncomfortable with going into detail regarding what followed, but suffice it to say that I’ve basically been to hell and back. They did everything they could to ‘punish’ me, and some of the things they came up with were uniquely and creatively traumatic. If they had put half as much effort and sophistication into ‘teaching’ me as they did into attacking and tormenting me, I probably would still be happily and obliviously under their control today, a fresh new convert of their admittedly impressive sci-fi space religion.”
    • “It took all the willpower I had just to stay focused and not become a completely broken wreck through all of this. Most of the ‘abilities’ I had acquired under their guidance gradually faded away over the course of a few weeks, with the exception of a number of lucid dream skills that I had picked up along the way. As I began to approach something resembling recovery, all kinds of memories and perspective started coming back to me that I had lost along the way (which may have been intentionally withheld from me). I felt like a toxic fog had been lifted from me, and everything looked so different now. I looked back on the last couple years of my life, especially the preceding four months or so, and was shocked to find that it wasn’t what I thought it was.”
    • “I had seen some mind-blowingly incredible things and progressed in so many ways in what I thought represented cognitive and spiritual development, but the consequences were now apparent. Without realizing it, my personality had changed so much, and not for the better. I had alienated myself from many of my close friends, my romantic relationship had suffered, I had been much more depressed than I wanted to admit, and I had spent way too much of my free time alone and in the dark, becoming obsessed with progressively darker and weirder esoteric knowledge. I had been able to maintain a token amount of social interaction, just enough to convince myself I was still ‘normal,’ but it frequently left me feeling drained, and bored with the mere ‘meat puppets’ in this material plane who were but a pale reflection of what existed beyond it.”

Appendix B: What Happens When You Take Too Much 5-MeO-DMT – What Does Underfitting Look Like?

While I agree that oneness is really important (and indeed I have written extensively about philosophy of personal identity and I generally advocate for Open Individualism), I do not think that realizing we are God is going to solve everything. In particular, we still need ruthlessly pragmatic solutions to the problem of intense suffering.

Insofar as non-duality is used as a mood-enhancer, it seems to be unreliable. Oneness can lead to bad trips of loneliness, a fact that tends to be brushed off by its advocates. My assessment is that this effect is the result of negative valence rather than an inherent effect of the concept (or truth?) of oneness. Shaman Oak‘s Bad LSD Experience – NIRVANA SUCKS video is a rather typical version of this effect and it highlights its true underlying cause: since he took the LSD during a comedown from cocaine, his entire trip was colored by the negative valence of that state. The world “felt inherently lonely” because it had depression qualia all over it. Amplified and magnified through the kaleidoscopic funhouse of LSD’s annealing dynamics, such a feeling of loneliness can look universal and omniprevalent “no matter how you look at it”. But if you were to replace that feeling with something blissful, then the concept of oneness would be experienced as wonderful and enlightening. It is always important to remember the Tyranny of the Intentional Object: ideas and beliefs seem to us as having inherent goodness or badness, but how this is implemented under the surface relies on hedonic tone/valence “painting” those ideas. As David Pearce likes to say, “take care of happiness and the meaning of life will take care of itself”.

Counterexamples: We do know a number of people who have used these compounds extensively and who do not seem to exhibit noticeable underfitting or overfitting. In particular, we have interviewed someone who took 5-MeO-DMT in high doses everyday for six months and who does not seem to suffer from any serious epistemological issues (they contacted me because they had read my analysis of Gura’s month-long experiment and wanted to share their even more extreme experience). The same person has extensive experience (including daily use for months) with DMT, Salvia, DPT and their combinations. They can still hold a technically demanding job and sustain a family despite this. Needless to say, such a level of psychological robustness is exceedingly rare.

Appendix C: The Abstract of the Other Talks

DMTX as a 21st Century Mystery School

A talk by Carl Hayden Smith

This talk will focus on the prospects of being one of the first participants in the world to try DMTX (X=Extended) at Imperial College London (ICL). After being part of the DMT phase 1 and phase 2 trials (over the last 5 years) this research now moves into a whole new level of immersion. During this experiment the peak of the DMT state will be extended thanks to a continuous intravenous drip feeding of the entheogen. This arguably turns this ancient medicine into a new form of technology. Early findings of the research from Chris Timmerman (ICL) suggests that nnDMT produces the same brain signature as the dreaming state. During the extended state we may be better able to explore the hypothesis from Andrew Gallimore that nnDMT actually opens up an entirely novel, orthogonal reality.

The DMTX experiment potentially means that nnDMT could become the base layer of our subjective reality, being combined, exponentially, with everything in life. What are the implications of this? Is there a danger that the psychedelic state is being overly romanticised and that DMTX could be regarded as a new form of bio chemical VR? How will DMTX help with the integration problem? Maybe the problem of bringing our insight back from the liminal space isn’t that these experiences defy verbalization, but that our languages are not yet sufficient enough to describe these experiences.

Increased cortical signal diversity during psychedelic states and visually realistic neural network models of hallucinations

A talk by Michael Schartner

Global states of consciousness – such as general anaesthesia or REM sleep – can be characterised by metrics of signal diversity, showing that diverse cortical activity is a hallmark of consciousness. We found that signal diversity is elevated in classical psychedelic states, possibly explained by a larger repertoire of brain states – which would be in line with reports about openness, novel associations and levelled salience of all experiences during psychedelic states. This coarse description of the brain as a dynamical system with various degrees of diversity in activity is only one dimension to characterise such global states of consciousness. Neural network models of visual perception and its pharmacological perturbation may provide a more mechanistic model, showing how the balanced integration of prior and sensory information into conscious perception is regulated by serotonin.


Note: I am still open to e.g. the external reality of DMT beings. I find it unlikely, but evidence could convince me otherwise. We are not dogmatic about the models we present. Rather, they simply are the current “best fit” for the available evidence in conjunction with parsimony considerations (yes, we could even say that this model is what minimizes our free energy!). Cheers!


References (abstract & talk; Chicago Style):

Atasoy, S., Donnelly, I. and Pearson, J. (2016). Human brain networks function in connectome-specific harmonic waves. Nat Commun 7, 10340. https://doi.org/10.1038/ncomms10340

Atasoy, S., Roseman, L., Kaelen, M. et al. (2017). Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD. Sci Rep 7, 17661. https://doi.org/10.1038/s41598-017-17546-0

Carhart-Harris, R. L. (2018). The entropic brain -revisited. Neuropharmacology142, 167–178. doi:10.1016/j.neuropharm.2018.03.010.

Carhart-Harris, R. L., and Friston, K. J. (2019). REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics. Pharmacol. Rev.71, 316–344. doi:10.1124/pr.118.017160.

Gomez-Emilsson, A. (2017). Quantifying Bliss. https://qualiacomputing.com/2017/06/18/quantifying-bliss-talk-summary/ [Accessed April 30, 2021].

Gomez-Emilsson, A. (2020). Modeling Psychedelic Tracers with QRI’s Psychophysics Toolkit: The Tracer Replication Tool. Qualia Computing. https://qualiacomputing.com/2020/10/09/modeling-psychedelic-tracers-with-qris-psychophysics-toolkit-the-tracer-replication-tool/

Gomez-Emilsson, A. (2020). 5-MeO-DMT vs. N,N-DMT: The 9 Lenses. https://qualiacomputing.com/2020/07/01/5-meo-dmt-vs-nn-dmt-the-9-lenses/ [Accessed April 30, 2021].

Griffiths, R. R., Johnson, M. W., Carducci, M. A., Umbricht, A., Richards, W. A., Richards, B. D., Cosimano, M. P., and Klinedinst, M. A. (2016). Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. Journal of psychopharmacology (Oxford, England)30(12), 1181–1197. https://doi.org/10.1177/0269881116675513

Johnson, M. E. (2016). Principia Qualia. https://opentheory.net/PrincipiaQualia.pdf [Accessed April 30, 2021].

Johnson, M. E. (2017). Why we seek out pleasure: the Symmetry Theory of Homeostatic Regulation https://opentheory.net/2017/05/why-we-seek-out-pleasure-the-symmetry-theory-of-homeostatic-regulation [Accessed April 30, 2021].

Johnson, M. E. (2019). Neural Annealing: Toward a Neural Theory of Everything. https://opentheory.net/2019/11/neural-annealing-toward-a-neural-theory-of-everything/ [Accessed April 30, 2021].

Lehar, S. (1999). Harmonic Resonance Theory: An Alternative to the “Neuron Doctrine” Paradigm of Neurocomputation to Address Gestalt properties of perception. http://slehar.com/wwwRel/webstuff/hr1/hr1.html [Accessed April 30, 2021].

Luppi, A. I., Vohryzek, J., Kringelbach, M. L., Mediano, P. A. M., Craig, M. M., Adapa, R., Carhart-Harris, R. L., Roseman, L., Pappas, I., Finoia, P., Williams, G. B., Allanson, J., Pickard, J. D., Menon, D. K., Atasoy, S., & Stamatakis, E. A. (2020). Connectome Harmonic Decomposition of Human Brain Dynamics Reveals a Landscape of Consciousness [Preprint]. Neuroscience. https://doi.org/10.1101/2020.08.10.244459

Ross, S., Bossis, A., Guss, J., Agin-Liebes, G., Malone, T., Cohen, B., Mennenga, S. E., Belser, A., Kalliontzi, K., Babb, J., Su, Z., Corby, P., & Schmidt, B. L. (2016). Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial. Journal of psychopharmacology (Oxford, England)30(12), 1165–1180. https://doi.org/10.1177/0269881116675512

Safron, A. (2020). “Strengthened Beliefs Under Psychedelics (SEBUS)? A Commentary on “REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics”” PsyArXiv. November 30. doi:10.31234/osf.io/zqh4b.

Simler, K. (2013). Neurons Gone Wild. Melting Asphalt. https://meltingasphalt.com/neurons-gone-wild/ [Accessed April 30, 2021].

Wu, L., Gomez-Emilsson, A., and Zuckerman, A. (2020). QRI Psychophysics Toolkit, Qualia Research Institutehttps://psychophysics.qualiaresearchinstitute.org

Yaden, D., and Griffiths, R. R. (2020) The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects. CS Pharmacol. Transl. Sci. 2021, 4, 2, 568–572 https://doi.org/10.1021/acsptsci.0c00194

7 Recent Videos: Consciousness vs. Replicators, High Entropy Alloys of Experience, Sleep Paralysis Stories, Free-Wheeling Hallucinations, Zero Ontology, The Tyranny of the Intentional Object, And A Language for Psychedelic Experiences

[See: Previous 7-video package]

A Universal Plot – Consciousness vs. Pure Replicators: Gene Servants or Blissful Autopoietic Beings? (link)

What is the point of it all? What does it all mean?

In this talk I explain how we can meaningfully address these questions with the frame of “consciousness vs. pure replicators”. This framework allows us to re-interpret and unify all previous “scales of moral/conceptual development”. In turn, it makes solving disagreements in a principled way possible.

“Consciousness vs. Pure Replicators” is what I call “the universal plot of reality”; it is the highest level of narrative that determines what is “relevant to the plot” at any given point in time.

Whether consciousness succeeds at gaining control of its destiny and embarks on a collective journey of self-authorship, or whether we all end up being subservient cogs to a self-replicating mega-system whose one and only utility function is to self-perpetuate, is truly up in the air right now. So what can we do to support the interests of consciousness, then?

To aid consciousness we need more than good intentions (though those are still a key ingredient): I discuss how game theoretical considerations entail that in order for consciousness to succeed we will need to judiciously ally with specific replicator strategies. Being a “cooperatebot” towards anyone who claims to care about consciousness makes you liable to being resource-pumped. You need to verify that something makes sense also from the point of view of game theory; without a way to verify the ultimate values of others, coordinating with them at this level becomes extremely challenging. I suggest that a mature technology of intelligent bliss with objectively verifiable effects would be a game-changer. Once you’ve seen “it” (i.e. optimized bliss consciousness) you join everyone else in self-organizing around it.

If the world is to be taken over by something that cares about the wellbeing of consciousness, how this taking over process looks like may blindside us all. The power of “universal love” conquering all obstacles and creating a paradise for all may not be a New Age fantasy after all. Given the appropriate technology, it may turn out to be a live option…

Topics Covered: Kegan Levels of Development, Spiral Dynamics, Model of Hierarchical Complexity, Meta-Modernism, Qualia Formalism, Valence Structuralism, Pleasure Principle, Open Individualism, Universal Darwinism, Battle Between Good and Evil, Balance Between Good and Evil, Gradients of Wisdom, Consciousness vs. Pure Replicators, Wild Animal Suffering, Mistrusting DMT Entities, Super-Cooperator Cluster, Metta/Lovingkindness, State-Dependent Sexuality, Wireheading, Cooperation Technology, Game-Changing as a Strategy.

~Qualia of the Day: Kala Namak~

Further Readings:


High Entropy Alloys of Experience (link)

~Suggestion: Play a music album you like in the background while listening to this talk.~

How do we find the “gems” hidden in the state-space of consciousness?

In this talk I articulate why it is very likely that there is a huge number of undiscovered states of consciousness that are completely unique, irreducible, and wholistically “special”.

In metallurgy, a high-entropy alloy (HEA) is a mixture of five or more metals in high proportions, often giving rise to a single phase. Some HEAs have been found to have extremely desirable properties from the point of view of material science (such as being the best at both yield-strength and ultimate tensile strength at the same time). Given the huge space of possible mixtures of metals, finding these carefully balanced mixtures with unique emergent properties is both a science and an art. It calls for intelligent strategies to explore the state-space of possible alloys!

I suggest that in the realm of consciousness there are also states that would be appropriate to describe as “high entropy alloys of experience”. I go into how this framework can help us understand unique scents*. We then explore how the receptor affinity profiles of drugs, drug cocktails, and drug schedules can give rise to unique HEA-like states of mind. I then also discuss how memeplexes have various degrees of total complexity, and how this makes some more receptive to dealing with complexity in the world than others. I offer that I really appreciate the HEA-like memeplexes that get expressed in places like EAGlobal, The Science of Consciousness, and Psychedelic Science conferences. I conclude by reflecting on how a “productive mindset” or mood optimized for a specific intellectual job is likely to be HEA-like because it requires the careful balance between many different facets of the mind.

Topics you will master after seeing this talk for even just one time**: High Entropy Alloys, Bronze and Iron Age, Equiatomic Alloys, People Clusters in Parties, Scents, Sexual Orientation, Gay Fragrances, Memeplexes and Mindsets, Vibe of Groups, Energy Parameter, Frozen Food, Crystallites, Space Groups, The Science of Consciousness, EAGlobal, Psychedelic Science, Search Heuristics, DMT as “Competing Clusters of Synchrony”, Birthday Cake Flavor, Cellular Automata, Optimal Mood for Productivity.

*(HEAs: Le Male by JPG, Bleu de Chanel, Mitsouko by Guerlain. Non-HEAs: Tommy Girl by Tommy Hilfiger, Habit Rouge by Guerlain, Amazing Grace Ballet Rose by Philosophy)

**More like “topics barely touched upon”.

Further Readings:

Heterosexual males and females preferred odours from heterosexual males relative to gay males; gay males preferred odours from other gay males.

Source: Sense of smell is linked to sexual orientation, study reveals

If the goal is to avoid the formation of such phases, simply mixing together five or more elements in near-equiatomic concentrations is unlikely to be a useful approach. Even multi-component alloys that are initially single phase after solidification tend to separate into multiple metallic and intermetallic phases when annealed at intermediate temperatures.

Source: High-entropy Alloys (literature review)

Featured image source: @fractjack


6 Spooky Sleep Paralysis Stories (link)

I estimate that I have experienced between 100 and 200 sleep paralysis, many of which were lucid (meaning that I knew I was experiencing a sleep paralysis). In this video I articulate what I have learned from all of these experiences, share some particularly strange stories, and give you tips for how to get out of a sleep paralysis if you find yourself trapped in one.

Topics Covered: Hyperbolic curvature in pasta, dream music, phenomenal viscosity, DXM, imperfect sensory gating, “radio is playing” hallucinations, Dredg – Album: El Cielo · Song: Scissor Lock, taking psychedelics while dreaming, lucid dreams, dopaminergics, controlling the powerful vibrations of sleep paralysis, recursive depth, false awakenings, whimpering, noting meditation, and techniques for escaping a sleep paralysis.

~Qualia of the Day: Gigli/Campanelle Pasta~

Further Readings:

Niacinamide helps in sleep enhancement as evidenced in a 3-week study of six subjects with normal sleep patterns and two with insomnia using electroencephalograms, electromyograms, and electrooculograms to evaluate sleep patterns at baseline and after niacinamide treatment. There was a significant increase in REM sleep in all normal-sleeping subjects, but the two subjects with moderate to severe insomnia experienced significant increases in REM sleep by the third week; awake time was also significantly decreased (Robinson et al., 1977).

(source)

Free-Wheeling Hallucinations: Be the Free-Willed God of Your Inner World-Simulation (link)

Once you realize that you inhabit a world-simulation sustained by your neuronal soil it is natural to ask: why can’t I control its contents? Why can’t I make myself hallucinate whatever I want?

It can be frustrating to realize one lacks control over something that should be truly “ours” – our raw unmediated experience! We could, and perhaps should, be the rightful masters of our very own conscious experience, yet for the most part we remain powerless to explore its possible states at will.

In this video I discuss the existence of some states of consciousness in which you do own and control the contents of your experience. Think of it as acquiring an “experience editor”: an interface with your experience that enables you to modify it at will while keeping the modifications stable.

A lucid dream would be an example of a somewhat fluid and unreliable free-wheeling hallucination. The free-wheeling hallucinations I describe here are much more general, stable, reliable, intense, and hedonic than lucid dreams. More so, to spin up free-wheeling hallucinations could amount to far more than being just a fun activity. Doing so may come to be an extremely valuable tool for a new paradigm of consciousness research! All of the parameters of experience that remain outside of our control under normal circumstances can be studied (both from a first and third person point of view) while in a free-wheeling hallucination! One can conduct a sort of “qualia chemistry” and repeat experiments to get reliable accounts of the behavior of consciousness under exotic (yet controlled) circumstances. Artifacts such as the valence-symmetry correspondance can be inspected in detail. Ultimately, this paradigm may allow us to chart the state-space of consciousness in terms of “edit distances” or “sequence of symmetry breaking operations” away from “formless consciousness”.

I then go on to explain that “knowing everything about your world-simulation” does not entail that the experience will be boring. Hedonic tone can be dissociated from novelty, but we don’t even need to go that far. It suffices to point out that you can set up the parameters of your world-simulation so that it unfolds in a chaotic way, and thus is impossible to predict. Additionally, you cannot really predict what you yourself will think in the future, so the whole setup can continue to generate novelty almost indefinitely (up to one’s storage capacity/size of the state-space/heat death of the universe).

I conclude by exercising my free will.

Topics Covered: Energy Parameter, Predictive Coding, Free Energy Principle, Kolmogorov Complexity of Experience, Principia Qualia, Super Free Will, Quality Trip Reports, DXM + THC Combo, LSD + Ketamine + THC Combo, “Experience Editors”, Qualia Critters, Fire Kasina, Color Control, Qualia Chemistry, Agenthood, Coumarin, Chamomile Tea.

~Qualia of the Day: You Have to Watch the Video~

Further Readings:

Chamomile consists of several ingredients including coumarin, glycoside, herniarin, flavonoid, farnesol, nerolidol and germacranolide. Despite the presence of coumarin, as chamomile’s effect on the coagulation system has not yet been studied, it is unknown if a clinically significant drug-herb interaction exists with antiplatelet/anticoagulant drugs. However, until more information is available, it is not recommended to use these substances concurrently.

Source: Herbal medication: potential for adverse interactions with analgesic drugs

Why Does Anything Exist? Zero Ontology, Physical Information, and Pure Awareness (link)

Why is there something rather than nothing? In this video I take this question very seriously and approach it with optimism. I say (a) this is a meaningful and valid question, and (b) it has a real and satisfying answer. The overall explanation space I explore is that of David Pearce’s Zero Ontology, which postulates that the multiverse is implied by the preservation of “zero information”.

In order to understand Zero Ontology we need to do some conceptual groundwork. So I walk the listener (you, were you to accept this journey) through several concepts that make the question go from “impossible to answer” or even “meaningless” to something that at least conceivably seems possible to solve.

First, we need to sidesteps the common tropes of our habitual modes of thinking, such as expecting answers to come in the form of “causal explanations”. No matter how you look at it, whether the universe extends back forever or not, a causal explanation for the origin of the universe is logically impossible to derive. Instead, we have to think in a radically different way, which is by way of frameworks for implication rather than causation. This opens us up to the possibility that exotic modes of thinking capable of representing what is entailed by “nothing” will show in turn that “something” follows from it. This helps us make sense of Pearce’s argument: the “nothing” we are looking for is not the “common sense” view of the term, but rather a more refined post-theoretical concept that is ill-fitted to the human mind for the time being.

In particular, Pearce focuses on how “no information” may be “what nothing is”. Thus, Zero Ontology attempts to formalize the “fact of inexistence” by reconceptualizing information as “ruling out possibilities”. Based on this alternate concept we see that math, physics, and phenomenology share the common thread of being possible to “construct out of nothing”. In math, the empty set can be used to derive all of arithmetic. In physics the Standard Model is a surprisingly simple theory that can be derived from first principles by imposing the “need for symmetry”. The total energy, charge, momentum, etc. of the universe is zero! And in phenomenology, we encounter a lot of cases where apparently all of the possible flavors of a qualia variety seem to “cancel out” into “pure being” or “raw awareness”. The simplest example is how experiencing “all phenomenal colors at once” (a kind of rainbow effect, but including magenta) seems to be interchangeable with “colorless phenomenal light”.

I tie all of this together and talk about how Zero Ontology allows us to reconceptualize “God/Being” as “unconstrained reality” or “boundarylessness”. I discuss how we could perhaps even probe Zero Ontology empirically in a direct way if we were to train enough physicists, mathematicians, philosophers, computer scientists, etc. to go into high Jhana or 5-MeO-DMT states and then quantify the properties of the fundamental fields implementing these experiences.

I conclude with an analogy to Borges’ Library of Babel (or a quantum version thereof) and why we may be in it. In fact, “be it”.

David Pearce: “A theory that explains everything explains nothing”, protests the critic of Everettian QM. To which we may reply, rather tentatively: yes, precisely.

Topics Covered: The Concept of Nothing, Three Characteristics, Illusion, Limitations of the Medium of Thought, Amusing Ourselves to Death, Redefining Information, Empty Set Arithmetic, Preserved Quantities of Physics, Symmetry and Noether’s Theorem, QFT, Path Integrals, Jhanas, 5-MeO-DMT, Symmetries in Qualia, Quantum Library of Babel, Black Hole Information Paradox.

~Qualia of the Day: Thinking About Nothing~

Further Readings:


The Tyranny of the Intentional Object: Universal Addictions, Meaning Abuse, and Denied Self-Insights (link)

What is it that we truly want? Why do so many people believe that meaning is better than happiness?

In this talk I discuss what we call “the tyranny of the intentional object”, which refers to the tendency for the mind to believe that “what it wants” is semantically meaningful experiences. In reality, what we want under the surface is to avoid negative valence and achieve sustainable positive valence states of consciousness.

I explain that evolution has “hooked us” on particular sources of pleasure in such a way that this is not introspectively accessible to us. We often need specific semantic content to work as a “key” for the “lock” of high-valence states of consciousness. I explain how we are all born chronic (endogenous) opioid addicts, and how our reward architecture is so coercive that we often fail to recognize this because thinking about it makes us feel bad (and thus ironically confirming the situation we are trying to be in denial about!).

I go on to provide my current thoughts on the nature of meaning. Beyond “sense and reference” we find that “felt-sense” is actually what meaning is “made of”. But not any kind of felt-sense. I posit that the felt-senses that we describe as richly meaningful tend to have the following properties: high levels of intention, coherence of attention field lines, a “field syntax”, and a high level of “potential to affect valence”. Valence and meaning are deeply connected but are not identical: we can find corner cases of high-valence but meaningless states of mind and vice versa (though they rare).

Meaning is no less liable to be “abused” than hard drugs: we often find ourselves scratching the bottom of the barrel of our meaning-making structures when things go wrong. I advise against doing this, and instead endorse the use of equanimity when faced with the absurd and Chapman’s “Meaningness” approach: to think of meaning as a gradient rather than in black and white terms. Do take advantage of opportunities for high levels of meaning, but do not rely on them and think they are universal. Indeed “meaning abuse” is a recipe for broken hearts and misguided idealistic solutions to problems that can be easily addressed pragmatically.

Finally, I steelman the importance of “high-dimensional valence” and explain why in turn usually pursuing meaning is indeed much better than shallow pleasure.

~Qualia of the Day: Clean Air~

Further Readings:

[T]he heroin addict will do anything to get another fix: lie, cheat, steal and worse. Natural selection has stumbled on and harnessed Nature’s own version of heroin. Our endogenous opioid system ensures that biological life behaves in callous but genetically adaptive ways. […] All complex animal life is “paid” in junk: the addictive dribble of opioids in our hedonic hotspots released when we act in ways that tend to maximise the inclusive fitness of our genes in the environment of evolutionary adaptedness (EEA). The pleasure-pain axis is coercive. Barring self-deliverance, we can’t opt out. Our “reward” circuitry hardwires opioid addiction and the complex rationalisations it spawns. Human history confirms we’ll do anything to obtain more opioids to feed our habit. The mesolimbic dopamine system enables us to anticipate our next fix and act accordingly: an insidious interplay of “wanting” and “liking”. We enslave and kill billions of sentient beings from other species to gratify our cravings. We feed the corpses of our victims to our offspring. So the vicious cycle of abuse continues.

David Pearce: Quora Responses

A Language for Psychedelic Experiences: Algorithmic Reductions, Field Operators, and Dimensionality (link)

Psychedelic experiences are notoriously difficult to describe. But are they truly ineffable, or do we simply lack the words, syntax, and grammar to articulate them? Optimistically, groups who take seriously the exploration of exotic states of consciousness could create a common ground of semantic primitives to be independently verified and used as the building blocks of a language for the “psychedelic medium of thought”.

In this video I present some ideas for a possible “psychedelic language” based on QRI paradigms and recent experience reports. I go over the article “Algorithmic Reduction of Psychedelic States” and the value of breaking the psychedelic experience in terms of a minimal set of “basic effects” whose stacking and composition gives rise to the wild zoo of effects one observes. I point out that algorithmic reductions can have explanatory power even if they do not provide a clear answer about the nature of the substrate of experience. Importantly, since I wrote that article we have developed a far higher-resolution understanding of exotic states of consciousness:

We suggest that a remarkably fruitful strategy for pointing at a whole family of psychedelic effects comes in the form of “field operators” that change the qualitative properties of our experiential fields. I provide a detailed description of what we call the “world-sheet” of experience and how it encodes emotional and semantic content in its very structure. The world-sheet can have tension, relaxation, different types of resonance and buzzing entrainment, twisting, curling, divergence (with vortices and anti-vortices in the attention field-lines), dissonance, consonance, noise, release, curvature, holographic properties, and dimensionality. I explain that in a psychedelic state, you explore higher up regions in the “Hamiltonian of the field”, meaning that you instantiate field configurations with higher levels of energy. There, we observer interesting trade-offs between the hyperbolicity of the field and its dimensionality. It can instantiate fractals of many sorts (in polar, cartesian, and other coordinate systems) by multi-scale entrainment. Time loops and moments of eternity result from this process iterated over all sensory modalities. The field contains meta-data implicitly encoded in its periphery which you can use for tacit information processing. Semantic content and preferences are encoded in terms of the patterns of attraction and repulsion of the attention-field lines. And so much more (watch the whole video for the entire story).

I conclude by saying that a steady meditation practice can be highly synergistic with psychedelics. Metta/loving-kindness can manifest in the form of smooth, coherent, high-dimensional, and consonant regions of the world-sheet and make the experience way more manageable, wholesome, and enriching. Equanimity, concentration, and sensory clarity are all synergistic with the state, and I posit that using “high-dimensionality” as the annealing target may accelerate the development of these traits in everyday life.

Please consider donating to QRI if you want to see this line of research make waves in academia and expand the Overtone Window for the science of consciousness. Funds will allow us to carry out key scientific experiments to validate models and develop technologies to reduce suffering at scale: https://www.qualiaresearchinstitute.org/donate

~Qualia of the Day: The Phenomenal Silence of Each Field Modality~

Further Readings:


That’s it for now!

Until next time!

Infinite bliss!

– Andrés

7 Recent Videos: Rational Analysis of 5-MeO-DMT, Utility Monsters, Neroli, Phenomenal Time, Benzo Withdrawal, Scale-Specific Network Geometry, and Why DMT Feels So Real

5-MeO-DMT: A Rational Analysis at Last (link)

Topics covered: Non-Duality, Symmetry, Valence, Neural Annealing, and Topological Segmentation.

See also:


Befriending Utility Monsters: Being the Adult in the Room When Talking About the Hedonic Extremes (link)

In this episode I connect a broad variety of topics with the following common thread: “What does it mean to be the adult in the room when dealing with extremely valenced states of consciousness?” Essentially, a talk on Utility Monsters.

Concretely, what does it mean to be responsible and sensible when confronted with the fact that pain and pleasure follow a long tail distribution? When discussing ultra-painful or ultra-blissful experiences one needs to take off the glasses we use to reason about “room temperature consciousness” and put on glasses that actually take these states with the seriousness they deserve.

Topics discussed include: The partial 5HT3 antagonism of ginger juice, kidney stones from vitamin C supplementation, 2C-E nausea, phenibut withdrawal, akathisia as a remarkably common side effect of psychiatric medication (neuroleptics, benzos, and SSRIs), negative 5-MeO-DMT trips, the book “LSD and the Mind of the Universe”, turbulence and laminar flow in the “energy body”, being a “mom” at a festival, and more.

Further readings on these topics:


Mapping State-Spaces of Consciousness: The Neroli Neighborhood (link)

What would it be like to have a scent-based medium of thought, with grammar, generative syntax, clauses, subordinate clauses, field geometry, and intentionality? How do we go about exploring the full state-space of scents (or any other qualia variety)?

Topics Covered in this Video: The State-space of Consciousness, Mapping State-Spaces, David Pearce at Oxford, Qualia Enrichment Kits, Character Impact vs. Flavors, Linalool Variants, Clusters of Neroli Scents, Neroli in Perfumes, Neroli vs. Orange Blossom vs. Petigrain vs. Orange/Mandarin/Lemon/Lime, High-Entropy Alloys of Scent, Musks as Reverb and Brown Noise, “Neroli Reconstructions” (synthetic), Semi-synthetic Mixtures, Winner-Takes-All Dynamics in Qualia Spaces, Multi-Phasic Scents, and Non-Euclidean State-Spaces.

Neroli Reconstruction Example:

4 – Linalool
3 – Linalyl Acetate
3 – Valencene
3 – Beta Pinene
2 – Nerolione
2 – Nerolidol
2 – Geraniol Coeur
2 – Hedione
2 – Farnesene
1 – D-Limonene
1 – Nerol
1 – Ambercore
1 – Linalool Oxyde
70 – Ethanol

Further readings:


What is Time? Explaining Time-Loops, Moments of Eternity, Time Branching, Time Reversal, and More… (link)

What is (phenomenal) time?

The feeling of time passing is not the same as physical time.

Albert Einstein discovered that “Newtonian time” was a special case of physical time, since gravity, relativity, and the constancy of the speed of light entails that space, time, mass, and gravity are intimately connected. He, in a sense, discovered a generalization of our common-sense notion of physical time; a generalization which accounts for the effects of moving and accelerating frames of reference on the relative passage of time between observers. Physical time, it turns out, could manifest in many more (exotic) ways than was previously thought.

Likewise, we find that our everyday phenomenal time (i.e. the feeling of time passing) is a special case of a far more general set of possible time-like qualities of experience. In particular, in this video I discuss “exotic phenomenal time” experiences, which include oddities such as time-loops, moments of eternity, time branching, and time reversal. I then go on to explain these exotic phenomenal time experiences with a model we call the “pseudo-time arrow”, which involves implicit causality in the network of sensations we experience on each “moment of experience”. Thus we realize that phenomenal time is an incredibly general property! It turns out that we haven’t even scratched the surface of what’s possible here… it’s about time we do so.

Further readings on this topic:


Benzos: Why the Withdrawal is Worse than the High is Good (+ Flumazenil/NAD+ Anti-Tolerance Action) (link)

Most people have low-resolution models of how drug tolerance works. Folk theories that “what goes up must come down” and theories in the medical establishment about how you can “stabilize a patient on a dose” and expect optimal effects long term get in the way of actually looking at how tolerance works.

In this video I explain why benzo withdrawal is far worse than the high they give you is good.

Core arguments presented:

  1. Benzos can treat anxiety, insomnia, palpitations, seizures, hallucinations, etc. If you use them to treat one of these symptoms, the rebound will nonetheless involve all of them.
  2. Kindling – How long-term use leads to neural annealing of the “withdrawal neural patterns”.
  3. Amnesia effects prevent you from remembering the good parts/only remembering the bad parts.
  4. Neurotoxicity from long-term benzo use makes it harder for your brain to heal.
  5. Arousal as a multiplier of consciousness: on benzos the “high” is low arousal and the withdrawal is high arousal (compared to stimulants where you at least will “sleep through the withdrawal”).
  6. Tolerance still builds up even when you don’t have a “psychoactive dose” in your body – meaning that the extremely long half-life of clonazepam and diazepam and their metabolites (50h+) entails that you still develop long-term tolerance even with weekly or biweekly use!

I then go into how the (empirically false) common-sense view of drug tolerance is delaying promising research avenues, such as “anti-tolerance drugs” (see links below). In particular, NAD+ IV and Flumazenil seem to have large effect sizes for treating benzo withdrawals. I AM NOT CONFIDENT THAT THEY WORK, but I think it is silly to not look into them with our best science at this point. Clinical trials for NAD+ IV therapy for drug withdrawal are underway, and the research to date on flumazenil seems extremely promising. Please let me know if you have any experience using either of these two tools and whether you had success with them or not.

Note: These treatments may also generalize to other GABAergic drugs like gabapentin, alcohol, and phenibut (which also have horrible withdrawals, but are far shorter than benzo withdrawal).

Further readings:

Epileptic patients who have become tolerant to the anti-seizure effects of the benzodiazepine clonazepam became seizure-free for several days after treatment with 1.5 mg of flumazenil.[14] Similarly, patients who were dependent on high doses of benzodiazepines […] were able to be stabilised on a low dose of clonazepam after 7–8 days of treatment with flumazenil.[15]”

Flumazenil has been tested against placebo in benzo-dependent subjects. Results showed that typical benzodiazepine withdrawal effects were reversed with few to no symptoms.[16] Flumazenil was also shown to produce significantly fewer withdrawal symptoms than saline in a randomized, placebo-controlled study with benzodiazepine-dependent subjects. Additionally, relapse rates were much lower during subsequent follow-up.[17]

Source: Flumazenil: Treatment for benzodiazepine dependence & tolerance

Scale-Specific Network Geometry (link)

Is it possible for the “natural growth” of a pandemic to be slower than exponential no matter where it starts? What are ways in which we can leverage the graphical properties of the “contact network” of humanity in order to control contagious diseases? In this video I offer a novel way of analyzing and designing networks that may allow us to easily prevent the exponential growth of future pandemics.

Topics covered: The difference between the aesthetic of pure math vs. applied statistics when it comes to making sense of graphs. Applications of graph analysis. Identifying people with a high centrality in social networks. Klout scores. Graphlets. Kinds of graphs: geometric, small world, scale-free, empirical (galactic core + “whiskers”). Pandemics being difficult to control due to exponential growth. Using a sort of “pandemic Klout score” to prioritize who to quarantine, who to vaccinate first. The network properties that made the plague spread so slowly in the Middle Ages. Toroidal planets as having linear pandemic growth after a certain threshold number of infections. Non-integer graph dimensionality. Dimensional chokes. And… kitchen sponges.

Readings either referenced in the video or useful to learn more about this topic:

Leskovec’s paper (the last link above):

Main Empirical Findings: Our results suggest a rather detailed and somewhat counterintuitive picture of the community structure in large networks. Several qualitative properties of community structure are nearly universal:

• Up to a size scale, which empirically is roughly 100 nodes, there not only exist well-separated communities, but also the slope of the network community profile plot is generally sloping downward. (See Fig. 1(a).) This latter point suggests, and empirically we often observe, that smaller communities can be combined into meaningful larger communities.

• At size scale of 100 nodes, we often observe the global minimum of the network community profile plot. (Although these are the “best” communities in the entire graph, they are usually connected to the remainder of the network by just a single edge.)

• Above the size scale of roughly 100 nodes, the network community profile plot gradually increases, and thus there is a nearly inverse relationship between community size and community quality. This upward slope suggests, and empirically we often observe, that as a function of increasing size, the best possible communities as they grow become more and more “blended into” the remainder of the network.

We have also examined in detail the structure of our social and information networks. We have observed that an ‘jellyfish’ or ‘octopus’ model [33, 7] provides a rough first approximation to structure of many of the networks we have examined.

Ps. Forgot to explain the sponge’s relevance: the scale-specific network geometry of a sponge is roughly hyperbolic at a small scale. Then the material is cubic at medium scale. And at the scale where you look at it as flat (being a sheet with finite thickness) it is two dimensional.


Why Does DMT Feel So Real? Multi-modal Coherence, High Temperature Parameter, Tactile Hallucinations (link)

Why does DMT feel so “real”? Why does it feel like you experience genuine mind-independent realities on DMT?

In this video I explain that we all implicitly rely on a model of which signals are trustworthy and which ones are not. In particular, in order to avoid losing one’s mind during an intense exotic experience (such as those catalyzed by psychedelics, dissociatives, or meditation) one needs to (a) know that you are altered, (b) have a good model of what that alteration entails, and (c) that the alteration is not strong enough that it breaks down either (a) or (b). So drugs that make you forget you are under the influence, or that you don’t know how to model (or have a mistaken model of) can deeply disrupt your “web of trusted beliefs”.

I argue that one cannot really import the models that one learned from other psychedelics about “what psychedelics do” to DMT; DMT alters you in a far broader way. For example, most people on LSD may mistrust what they see, but they will not mistrust what they touch (touch stays a “trusted signal” on LSD). But on DMT you can experience tactile hallucinations that are coherent with one’s visions! “Crossing the veil” on DMT is not a visual experience: it’s a multi-modal experience, like entering a cave hiding behind a waterfall.

Some of the signals that DMT messes with that often convince people that what they experienced was mind-independent include:

  1. Hyperbolic geometry and mathematical complexity; experiencing “impossible objects”.
  2. Incredibly high-resolution multi-modal integration: hallucinations are “coherent” across senses.
  3. Philosophical qualia enhancement: it alters not only your senses and emotions, but also “the way you organize models of reality”.
  4. More “energized” experiences feel inherently more real, and DMT can increase the energy parameter to an extreme degree.
  5. Highly valenced experiences also feel more real – the bliss and the horror are interpreted as “belonging to the vibe of a reality” rather than being just a property of your experience.
  6. DMT can give you powerful hallucinations in every modality: not only visual hallucinations, but also tactile, auditory, scent, taste, and proprioception.
  7. Novel and exotic feelings of “electromagnetism”.
  8. Sense of “wisdom”.
  9. Knowledge of your feelings: the entities know more about you than you yourself know about yourself.

With all of these signals being liable to chaotic alterations on DMT it makes sense that even very bright and rational people may experience a “shift” in their beliefs about reality. The trusted signals will have altered their consilience point. And since each point of consilience between trusted signals entails a worldview, people who believe in the independent reality of the realms disclosed by DMT share trust in some signals most people don’t even know exist. We can expect some pushback for this analysis by people who trust any of the signals altered by DMT listed above. Which is fine! But… if we want to create a rational Super-Shulgin Academy to really make some serious progress in mapping-out the state-space of consciousness, we will need to prevent epistemological mishaps. I.e. We have to model insanity so that we ourselves can stay sane.

[Skip to 4:20 if you don’t care about the scent of rose – the Qualia of the Day today]

Further readings:

“The most common descriptive labels for the entity were being, guide, spirit, alien, and helper. […] Most respondents endorsed that the entity had the attributes of being conscious, intelligent, and benevolent, existed in some real but different dimension of reality, and continued to exist after the encounter.”

Source: Survey of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine: Phenomenology, interpretation, and enduring effects

That’s it for now!

Please feel free to suggest topics for future videos!

Infinite bliss!

– Andrés

The Symmetry Theory of Valence: 2020 Presentation

Presentation Given at the Centre for Psychedelic Research at Imperial College London by Andrés Gómez Emilsson (December 8th 2020)

 www.qualiaresearchinstitute.org

Transcribed with otter.ai. Edited for grammar and clarity by Mackenzie Dion.

Watch the talk on our Youtube channel.


So, the Symmetry Theory of Valence. Just defining terms so that we’re all on the same page. There’s this thing called core affect which is basically what you get when you apply dimensionality reduction techniques to any one of many areas of psychology. There’s a surprisingly robust pair of dimensions that emerge in co-occurrences of words or even descriptions of behavior. These two axes, arousal and valence, seem to account for about 60% of the variance in terms of what information emotional words contain. And I mean, roughly speaking, arousal is the level of activation, how energetic you are, and valence is how good you feel. Most of what I’m going to be talking about is valence. That said, you need to also consider arousal in the picture to know what this is all about. Just a few examples: you have high arousal, high valence, so that would be kind of excitement and anticipation. But you also can have high energy, but not feeling really good, and that would be kind of anxiety or anger or irritation. Likewise, you have depression, which is low arousal, low valence, and serenity is peaceful, blissful calm, that would be low arousal, high valence. 

This is just one example of one of the ways in which you can recover these dimensions of valence and arousal. This was a little study we conducted years ago. We were studying people who have experiences with all kinds of substances online. We were giving them the survey, where they were going to describe a particular substance along something like 70 different dimensions. Then I conducted factor analysis on that data set. Interestingly, we have three core dimensions of valence or valence-related axes, which give you a sense of, okay, what is the space of possible effects that you can get from some substances. There were actually six dimensions that emerged, but three of them are valence-related:

We have slow euphoria, which is equivalent to low arousal, high valence with top terms like calming and relieving. The negative predictors of it would be something like anxiety, producing difficult bodily discomfort. Fast euphoria is the sort of thing you get with stimulants, you know, energizing, sociable, the opposite of feeling spaced out and confused.

The other axis that kind of emerged was this notion of spiritual euphoria. That’s the term I used back then. I also used the term significance, or saliency nowadays. Now I would actually use the term criticality for other reasons that we can go into. There’s this other kind of axis for how you can experience intense valence with substances, which is different from slow and fast euphoria, which would roughly correspond to the psychedelic space. And that, you know, gets marked with things such as mystical, incredible, life changing. The opposite of that is trivial, self-centered, or irrelevant or something like that. This is just to complete the cube. And, you know, in a sense…

This is just a kind of change of basis, where you still get, in a sense, the valence dimension emerging out of this dimensionality reduction analysis. If you were to apply just one dimension, you know, if you ask the factor analysis to just give you one factor, it is going to be the valence factor. That’s the axis that accounts for most of the variance for the effects of drugs.

I’ve got to say that I absolutely acknowledge that emotions are far more complex and intricate than just valence and arousal. This is the result of my master’s thesis where we were analyzing this thing called mood updates, how people feel over time, day after day. I was computing the transition probabilities between emotions, and you can do cluster analysis here and finding attractors. You’ll see that there’s additional information. That said, we concluded that a big chunk of the additional information that is not valence and arousal is actually information about your trajectory in the valence arousal space. For example, we found there would be emotions that because of what they tell you about your emotional dynamics we called gateway emotions, like feeling relieved and feeling hopeful. These terms contain information that you were in a negative, kind of depressive attractor, and you’re moving towards the positive high arousal attractor. In essence, the terms we use for emotions give you not only information about where you are in the valence-arousal space but also what is your trajectory in that space. But in a sense, valence and arousal still account for a very, very big chunk of what an emotion is. Okay, so hopefully I’ve convinced you of the importance of valence, at least in this context.

Now, let’s jump into the Symmetry Theory of Valence (STV). The overall hypotheses and the first explicit argument for it appeared in this really, really awesome work by my collaborator, Michael Johnson, Principia Qualia. He has a really interesting skeleton of an argument that points to a lot of research threads that are really worth getting into. I highly recommend digging into this work.

One of the things that it lays out is the kind of conceptual framework to make sense of what type of thing valence might be. I’ll just define a couple terms, which is, first qualia formalism. If there’s one thing at QRI we are married to, you could say, it would be qualia formalism. That is, for any conscious experience, there exists a mathematical object isomorphic to it. We can make an analogy here to something like electromagnetism where we used to have lightning, and electricity, and magnets, and all of that seemed sort of somehow thinly related. But, it turns out that there’s actually just four equations of electromagnetism that tie together all of that phenomena. And you can compare it to something like élan vital, the essence of life. People used to think that maybe there is some kind of a substance that determines whether you’re alive or not. And we would say that, well, that kind of fell through, you know, in the end there is molecular complexity under more molecular complexity. There doesn’t seem to be such a thing as “life itself”. Life is not formalizable in the same way as electromagnetism is, but something that we would claim at QRI or we could even say something that we assume at QRI, because we believe it is a very generative frame, is that yes, there will be a set of deep mathematical structures to consciousness. In particular, if you expand this into other areas, we also think this is going to apply to valence: that there is going to be a deep and rich mathematical structure to valence, and that notion is called valence structuralism.

In Principia Qualia by Mike Johnson, he has this argument for it, which I definitely recommend reading, especially if you have the aesthetic of a physicist. I think you’ll really like this work, because I think it’s really, really good in that sense. What I’m going to do now is try to give you a kind of intuition for it. And then the whole empirical argument.

Importantly, there are a lot of theories of what valence is. Mike looked at the literature, did a very deep dive into it, and realized that they’re usually unsatisfactory, or at the very least, they don’t get at the true core of what an explanation for valence should be like. So basically, you have these accounts of, for example, valence sees how the brain represents value. Ultimately, that’s just a correlation. Value is a fuzzy abstraction. Some people think valence is the presence of opioids in the brain. But if you inject opioids in different parts of the brain, it doesn’t always feel good. It actually needs to be injected in a very narrow range of stripes in the pleasure centers, and otherwise, it just causes strange feelings or wanting, but it’s not the signature of valence itself. Or, for example, the pleasure centers. Just because you’re calling something “the pleasure center”, and it’s correlated with feeling good, it doesn’t mean you have an explanation. It’s not a very insightful, illuminating, account of valence. 

So what could it be? I’ll focus to a large extent on what we are going to call bliss, which is just very positive valence. What is that? What is very positive valence? What is the sense of ecstasy, bliss, intense happiness? There’s a lot of intuitions. Definitely a lot of people think it’s some kind of spiritual signal, and I wouldn’t want to convince you out of that view. But the truth is that there are a lot of different spiritualities, and they sometimes say contradictory things. So it’s kind of strange to expect that there’s this underlying universal spiritual signal that whenever you’re doing something aligned with spirit, you feel good. Because sometimes you can do something very different than somebody else and still have that feeling. Also, the idea that it is “merely” chemical reactions in the brain, again, is not a super satisfactory explanation… same as with pleasure centers, health, few prediction errors, etc. Well, and in the end, I add, yes, symmetry and consciousness, which is what I will be arguing.

I also want to point out, and this is super important, that valence is not the same as healing, and it’s not the same as meaning. However, they’re correlated. I would also go as far as to say that high valence is necessary for healing and for meaning to a large extent. In a sense, you can have a lot of very high valence states that are actually very unhealthy for you. Just an example would be methamphetamine. It can feel great, but it’s unsustainable. To the extent that your nervous system is self-organizing around that high valence experience, it makes it kind of the center of your life. And, you know, it’s a dopamine releaser. It’s obviously unsustainable. You can’t actually do that long-term and expect good results. Whereas, something like meditation, or even psychedelics, because their tolerance mechanism is very, very different. You could say that, yeah, those might be high valence, highly meaningful, and also healing experiences.

So I just want to say that, you know, high valence doesn’t entail healing. And that in that sense, you might say, “Okay, why are we so interested in this?”, but I would say that high valence is a necessary condition for deep healing. And I would even go as far as to say that, for a psychedelic experience to be deeply healing, it has to involve high valence in one context or another. Of course, you may end up processing a lot of very difficult emotions. But ideally, it would be something that basically allows you to heal those difficult emotions and transform them into a state of mind that has many more of the positive qualities. 

And more so, high valence, even according to the Buddha, is an important factor for awakening. Of the seven factors for awakening, I would actually say about five of them are very connected to valence. Mindfulness, joy, relaxation, concentration, equanimity; they are kind of different flavors of high valence. They’re different ways in which a very high valence experience can manifest. The Buddha says that these are important things. Even if you only care about awakening, enlightenment, you may also care about the mathematics of valence. It might point you in the right direction as well.

I’ll also mention, there’s a big difference between the recipe of a state of consciousness and what you might call the review, or the description, of that state of consciousness. I’ll make an analogy with cooking: if you have cooking instructions for how to make a cake, sometimes it’s very counterintuitive what the cake is going to taste based on those instructions. Like “add yeast” for example. A lot of things in the recipe you may not know exactly how are going to actually affect the result. So, the recipe may look very different from the review of the state. I would say that for a lot of meditation states, or even just general life advice, this idea of don’t mindlessly chasing pleasure or trying to satisfy all of your existing desires compulsively gives counter-intuitive results. Yeah, chasing pleasure compulsively is not going to result in a sustainable high valence. To some extent, a lot of meditation instructions tell you to neither approach nor withdraw from emotions to develop equanimity. Since you are not engaging with your emotions, it sounds like the result is a fully neutral experience, right? It sounds like it’s unrelated to valence, almost cutting out the valence. But I would say: that’s just the recipe. Those are the instructions for how you manage your attention in order to eventually change your brain to actually generate these very healthy, sustainable, high valence states. So I definitely want to overcome this prejudice of thinking that high valence is unrelated to spirituality. No, I think they’re actually very deeply, intimately connected. 

Okay, so let’s go into the Symmetry Theory of Valence. I’ll just read these, but we will go into more depth into all of these. So, you know, we talked about qualia formalism, there is a mathematical object whose features are isomorphic to phenomenology. We believe that, yeah, harmony basically feels good because it’s symmetry over time. And basically, there’s kind of this duality between symmetry and space and synchrony in time. We will go over pleasure centers. The way we explain pleasure centers in this theory is that they are kind of tuning knobs (this was first proposed in Principia Qualia). They are there these bridges that, basically, when they get activated, they enable global large-scale synchrony in the brain. This is something that ultimately is very testable. Because if you can activate the pleasure centers, or inhibit whole brain harmony, we predict that’s going to actually negate the positive valence effects of the pleasure centers. Likewise, if we can induce large scale harmony, without activating the pleasure centers, or maybe even inhibiting the pleasure centers, we expect that to be a high valence state. So, it’s a cool, testable interpretation of what pleasure centers even are. 

Boredom is kind of an anti symmetry mechanism. So that’s why even if you look at a cathedral or something like that, you’re not going to be happy forever. You’re going to be happy for a little bit. Because your brain realizes that you’re not learning anything, and adds kind of this dissonance in order to make you move on to something else. We are wired in such a way that what helps us reproduce symmetrifies our consciousness. So, it’s not that high calorie food in and of itself is symmetrical, it’s not that it in and of itself is pleasant. It’s more that the way our nervous system is programmed is such that when you eat high calorie food, it triggers high valence. And that triggered high valence is what would be symmetrical, not necessarily the chemicals that you’re eating.

Importantly, valence, we think, has these three dimensions, which is positive, neutral, and negative. And you can actually have highly mixed experiences. You can have experiences, I don’t know, an example is you’re at a concert, enjoying yourself, but also you have to go to the bathroom, and you just broke up with your boyfriend. You can have these very complex mixed valence experiences, where parts of your experience are very pleasant, parts are very distressing, parts of those are very neutral, and that’s fine. At the same time, it still kind of collapses into this ultimately, “Hey, are you having a good time or not?”.

And something that the Symmetry Theory of Valence would say, and this is a pretty interesting kind of relationship, and I’ll explain it in a couple slides. This is just to kind of put it out there in your head to bounce around as we go on, which is that we expect there to be a very, very intimate relationship between information content, and basically the range of valence that you have access to. So in brief, for very, very high valence states of consciousness, we expect those to have very close to zero information. Whereas, when you have this state that is close to pure white noise, we expect that to be basically zero valence. Hopefully, this will make more sense as we go along.

These are just some illustrations of this principle. Actually, we expect that some of the most negative experiences out there will actually be pretty close to very, very highly symmetrical. I put this disjointed lattice at the bottom. And I would claim that something like a bad 5-MeO-DMT experience is actually something that is very regular, except for some strange disjoints, or imperfections, that cause profound dissonance. Whereas, if you’re in the pure noise kind of range, it all feels blah, it all feels really close to neutral.

When we say the state of consciousness is highly symmetrical and such, you know, let’s say, 5-MeO-DMT, or jhanas, or something like that, we expect these to actually show up in many ways. If you look at the biorhythms, like heart rate and breathing, that’s going to show up, symmetry is going to show up in some ways, being a different kind of projection of the latent state. I mean, ultimately, the formalism, you know, this mathematical object corresponds to consciousness is not observable directly, at least not right now. So we have to kind of rely on these projections, these interpretations of what’s going on, these ways of getting at this unobservable, underlying state. And EEG, connectome harmonics, biorhythms, and so on, are different ways of getting at it. I’ll show you at least empirically that it’s all so far consistent with the Symmetry Theory of Valence.

Here’s kind of the big plan. All of these different projections of this underlying state. So we have basically this stimulus. These are kind of visualized also to give you an intuition. So there’s stimuli, basically more symmetrical stimuli with higher valence, then there’s the endogenous bodily state, you know, biorhythms, as well. The CNS State, the actual, okay, what’s going on in your brain, then the formalism, and then the phenomenology of valence. When you have high valence, we expect (and what we see is) that there’s symmetry all across the board, in each of these different ways of looking at the state of consciousness. In each of these projections of the latent state.

So I’ll go on and start with phenomenology. I know that phenomenology is such a tricky thing. It’s so difficult to do, right. It’s so difficult to do. You make a lot of mistakes in phenomenology, get confused, and become self-deceived. So I mean, hopefully, the observation I’ll relate to you is going to show you that at least we’re taking care of some of the failure modes of phenomenology.

So, first of all, we distinguish between intentional content and phenomenal character. So, if you smoke DMT, and you experience, you know, you say something like “I saw a dragon with my own eyes” that doesn’t mean there was actually a mind-independent dragon out there. And, you know, I take seriously your report that you saw a dragon, but I don’t know how significant that is necessarily. On the other hand, if you describe “Oh, and by the way, the dragon had scales that had a symmetry group of what’s called the glide mirror symmetry group, and it had a 17 hertz strobing effect“. Okay, yes, so we’re getting more into the phenomenal character. You’re actually describing what it felt like, not only what it was about. I would make the claim that these observations of symmetry being related to valence are about the phenomenal character. I don’t care that much about, you know, “What was the journey? What was the content of the experience?” I care more about what it felt like, what are the features of it, and what we observe is that there’s a deep connection here.

So I’ll just give you some examples. Basically, introspect. You know, the difference between massage and bodily pain. Massage is kind of this very, very pleasant, harmonious, tactile pattern throughout your body that gives you these very nice waves of pleasure, as opposed to bodily pain. Bodily pain, if you introspect on it, it’s almost kind of like there’s like pinch points and discontinuities and fragmentations and deformations in your sense of self and the continuity of your skin or your felt sense of your inner organs. Basically, I would make the claim that bodily pain always manifests in one way or another as a kind of symmetry breaking operation. Now, definitely keep this in mind if you ever have a pain again, hopefully not.

Also, let’s say anxiety versus relaxation. Anxiety, you could almost describe it as, constant prediction errors. “Oh, did my heart do something strange? Is my leg positioned properly?”. It’s a state of mind where all of these little imperfections bubble up to your awareness. I would say it’s interrupting the flow of your attention and creating these pinch points and deformations in the way you experience the world. As opposed to relaxation, where you’re almost kind of just completely melted into it. And it’s so regular, you can almost filter out most of your bodily sensations. And in that sense I would argue it has a very symmetrical quality.

There’s also this whole argument Mike brings up which is the phenomenology concerning non-adaptiveness, the non-adaptiveness principle, which is that basically, there’s a bunch of things out there that feel really good, but that weren’t in our evolutionary environment. Those are hints; we consider those hints that hey, if something wasn’t in the African savanna but feels great, it probably means that it’s kind of directly hacking into the patterns of valence somehow. We didn’t evolve to filter those out or to not get absorbed by them. And yeah, here are some examples, but I’ll go deeper into those. 

Now, there’s also this exotic valence. Bodily pain, anxiety, relaxations: those would be examples of “normal valence”. It’s the valence that we’re all used to. But I would say that also in “strange valences”, like valences in weird states of consciousness, they also follow this pattern. That in some sense, symmetry explains their pleasantness. And I’ll give you some examples.

So, dream music. I’ve had the pleasure or displeasure, you could say, of having had a lot of sleep paralysis and lucid dreams, and this effect is something you can experience in either sleep paralysis or lucid dreams. If you’ve had a lucid dream, where you were making music, or you heard, you’re hallucinating that there was a radio playing, you will notice that, “Oh my gosh, the music can be beautiful, like… incredible”. And this music, maybe you have heard it before, maybe not. Maybe your brain is generating it on the fly. But it has a quality to it that is extraordinarily hedonic and pleasant. And I remember studying this on myself over many lucid dreaming experiences. At first, I thought, “Oh my gosh, my brain is just unlocking this ability to create awesome harmonies and melodies”. But then I ended up realizing that even if I just make a kind of an “om”, this meditation sound, even though that sound is extremely simple, the quality of the sound in the lucid dream is profound. I mean, it’s almost kind of a surround sound, like 360 surround sound, and stereoscopic and full of reverb and richness. 

I would claim that it’s actually because, during a dream state, your brain is more resonant. You can kind of enter into these very, very resonant attractors, and it’s that quality that makes the music so compelling, not the melody. If you transcribe the melody, the melody may not be very significant. It was how it sounded that was so profound in the music in the dream.

Then you have meditation. Even these images, maybe, I don’t know if this is cheating, but representations of meditation, like high attainments, and so on, they usually come with these beautiful symmetries and whatnot. If you examine the phenomenology of jhanas, how they’re described, there seems to be kind of this projection of less and less information content in your experience. Going from having all of your attention concentrated in one point to then the experience of completely perfectly smooth, boundless space to then just pure consciousness, and then the experience of neither nothing nor something. In a sense, that’s kind of approaching the limit of zero information. And then people report these jhana experiences, they’re not pleasant in a conventional sense. It’s not like eating ice cream or something like that, but they’re still very, very high valence. They’re blissful, in an exotic way. But, I do want to point out that there’s this fascinating, strange relationship here between low information content and the blissfulness and the healing quality of the state.

And then there is exotic valence from psychedelics. I mean, again, I don’t want you to focus on the intentional content, what was the experience about. What you thought, of course, can influence your valence, but it’s more about the phenomenal character. There’s this phenomena of tracers, you move your hand around, and you see copies laying around, and in a sense, it’s giving a temporal depth to your experience. It’s almost kind of adding a new dimension of time, where qualia can pile up. And usually, if the trip is good, you’ll notice that these tracers are in a harmonic relationship with each other. That is kind of the essence of what makes them feel so good.

Likewise, there’s a psychedelic texture repetition. You stare at a piece of grass on LSD, and it starts to symmetrify. And I would totally say this is exotic valence because you ask the person, and they will say “the ground was symmetrifying, and I don’t know why, but it was awesome”. There was something really cool about it, and why would that be? Our interpretation here is that psychedelics are, in a sense, unlocking the valence capacity of your visual cortex. It’s kind of transforming your cortex into a pleasure machine, basically allowing it to exhibit these profound symmetries, and that is what actually is making them feel so compelling. People will struggle to explain “Why were the visuals cool? Why were they interesting?”. When it comes down to it, I think it is the symmetry.

Interestingly, these are called the wallpaper symmetry groups. There’s 17 possible ways of tessellating a two dimensional space. From subjective reports, we know that any of these can be experienced on a psychedelic. The ground, kind of chaotically, will arrive at one attractor of symmetry. It could be any of these 17, and they all feel great. They’re all extremely aesthetic and beautiful and blissful in one way or another. But it’s kind of a testament to just how general this effect is.

I would make the claim, and this is obviously a strong claim, but it matters for something like therapy, psychedelic therapy. We recently saw this fascinating research on psilocybin for major depression, and that a lot of these effects are mediated by whether you had a mystical experience or not. I would say that if you did have a mystical experience, and it was healing, I would bet that while you were having that experience, the sense of space and time was basically extremely, extremely symmetrical. And here is kind of why it’s so confusing. Because you come back and you say, “Well, I saw Jesus”, and you think that you got healed because of Jesus. I don’t want to dissuade you from that view, but I would basically ask you “Okay, but when you experienced Jesus, what was the feeling of space and time?”. They might say something like, “Oh, it had a beautiful light. It had this beautiful harmony and rainbows”. And I’ll claim that if you introspect on them then that it’s actually the quality of phenomenal space and time that is healing and blissful. The meaning, the religious meaning, is something that is helping your mind basically concentrate on that space, and take it seriously as a way of propagating this negentropy in your nervous system.

Now, another place where this shows up super, super clearly, phenomenologically, is on DMT. I definitely recommend this article we wrote that basically charts the DMT space. You can know a lot about where you are in the DMT space by describing what is your energy level on the one hand, and then what is the information content on the other. I would say DMT states that have close to zero information content would be kind of these geometric, perfectly repeating, symmetry groups, either 2D or 3D. Whereas, more chaotic states would be kind of in the middle. The energy level would be a matter of dose. The “height” you reach is very, very dose-dependent. But then the valence, I think it’s very, very dependent on actually where in the axis of information content you find yourself in.

Here again, there’s this diagram that the most blissful experiences you may have on DMT are going to be on these kinds of honeycombs and perfectly symmetrical patterns. The most unpleasant experiences are going to be just right next to those, they are going to be kind of dissonant honeycombs. Whereas you know, when you get to complex narratives, like machine elves and alien realms and all of that stuff, those experiences would be very mixed in their valence. There’s both dissonance, consonance, symmetry, anti-symmetry; those are very complex experiences.

Now, the information content, we think of them as basically attractors in feedback systems. You may end up in a chaotic attractor, you may end up in a limit cycle or a fixed point. And that will determine how much information content the state has. 

Interestingly, this also can be used to describe the difference between DMT and 5-MeO-DMT. We think DMT tends to have a lot more information content. 

So you have these very rich patterns, and I would say competing synchronies. On DMT, there’s all of these slightly different frequencies that are competing for your attention and creating a narrative out of that. That is like a very mixed experience; it is both blissful and distressing at the same time.

Whereas 5-MeO-DMT, which is described as far more powerful emotionally, tends to give you this sense of pure space, like the feeling of the insight into emptiness, the feeling of infinite boundless consciousness, very little information content. Yet, it’s so emotionally impactful to such an extreme extent.

Interestingly, I would say, the reports do come out that on 5-MeO-DMT, you may have the best experience of your time, or you may have the worst experience of your life. It’s kind of bimodal. It’s either amazing or it’s extremely bad. Often, it starts out really bad and then it gets amazing. I would describe that in terms of kind of this annealing process where it basically starts with dissonance, and, over time, things synchronize, and you do end up where all of your nervous system is entrained to the same frequency, and that feels very, very blissful. Whereas DMT is always kind of in this mixed state. It is very difficult for DMT to be pure negative or pure positive. It’s always this mixed state. So I would say, yeah, this is kind of the phenomenological case for the Symmetry Theory of Valence.

I’m two thirds of the way through the presentation. I’m just gonna walk you through the empirical evidence. So we were talking about phenomenology; that’s one of the projections of this formalism and its symmetry. There’s symmetry in the formalism. It’s gonna manifest in some forms of phenomenological symmetry. Likewise, you know, if you use external stimuli in order to generate a state, like, let’s say, watching a movie, playing music, playing stroboscopic stimulation, there’s a lot of evidence that indicates that the symmetry of the stimuli is the leading factor for how pleasant or unpleasant the resulting state is. We have all of this research in vision.

These are just some examples. It’s so stunning, right? Even if you know the effect, you still get the valence response. You go to a cathedral and think “Okay, I’m not gonna get high valence, I’m not going to get high valence”. You still get the response. It’s pretty automatic. As long as it has this rich, deep symmetry, oftentimes, it’s going to be very beautiful. There’s something very compelling about this.

Just some random pictures to give you a sense of this.

Why does this feel good? It really has very little to do with our ancestral environment.

Anyway, this is such a robust effect that, with the symmetry of faces, for example, even face paint can be used to modify the valence. So, if you don’t have a perfectly symmetrical face, but you add symmetrical face paint with beautiful patterns, you’re going to be judged as more beautiful. It’s just such a strong effect, that it can actually modify your perception of how beautiful somebody is. Likewise, if you add asymmetrical patterns, you look less beautiful. Now, this, I wouldn’t say this is that strong of evidence because this actually does have an evolutionary reason. Symmetry in faces is a marker of mutational load. So I don’t put that much stock in, symmetry of faces being that relevant. But symmetry in other forms is where I think it’s so stunning. 

You also see this in symmetry in audio, basically, regular rhythms. Harmony is the leading predictor for whether a sound is going to be pleasant or unpleasant.

You know, this is Helmholtz’s big idea. He was the first one to figure out why playing two notes in a piano that are one semitone apart feels unpleasant. It’s because the harmonics are basically within what’s called the critical window. They generate beat patterns and the beat patterns can be described as basically symmetry breaking operations in the waveform. Those symmetry breaking operations, in essence, cause irritation. So basically, the more beating there is in sound, and the more beating across the spectrum, the more irritating and distracting and rough the sound is going to sound like. Whereas, when you have these harmonic relationships, you play one note, one piano note, and another at an octave of difference, the harmonics line up perfectly. Actually, the sound is very compressible because you don’t have this extra information of where all the other harmonics lie. They’re just the harmonic sequence. And that is universally described as a more pleasant sound.

When you add up all the harmonics, you get these interesting curves. The height here is the amount of dissonance. When you have a relationship of one to two, basically an octave, you have zero dissonance, and that feels really good. Now, music is very complicated. We have to factor in the boredom mechanism. If you just play the same octave over and over, you get bored, and there’s an inner sense of restlessness and dissonance. But if you just hear it for the first time, then there’s a super, super strong relationship between symmetry and valence.

These are just examples of a piano chord.

Dissonant sounds. I can send you a link to all of these sounds after the presentation*, but I have some links for a SoundCloud account where you can kind of get convinced that “Oh gosh, these are actually really bad sounds”. It’s not that I’m saying they’re bad. If you ask 100 people, like 99% of people will say they’re awful. 

Likewise, reverb basically symmetrifies any waveform. Reverb is almost kind of this hack that you take almost any dissonant sound and you add reverb to it and is going to sound a lot less bad, a lot less distracting, irritating, and so on. So this is comparing the sound of a baby crying, which by the way, like in our analysis, it shows that babies crying, it’s almost like their sound is optimized for dissonance. It’s almost kind of as dissonant as it gets for a sound made by a human. For good evolutionary reasons, it has to be distracting, and catch your attention, bring the desire to stop it. But you add reverb and to give you a sense, that’s like if the baby was in a huge cave, you get all these echoes averaging out the beat patterns. It sounds way better, way less distracting, probably not good from an evolutionary standpoint. But, it’s just a fascinating kind of transformation you can apply to any waveform.

And here, I just want to illustrate that valence can happen across the spectrum. So I also have this file**, and you’re welcome to listen to it after the presentation where you can have consonance anywhere in the spectrum, mixed in with dissonance anywhere in the spectrum, mixed in with noise anywhere in the spectrum. That ends up basically creating these very mixed states. 

So basically, when I say “Oh, I had a mixed experience, a mixed valence experience” that underdetermines what I experienced because we don’t know if the positive part was in the high frequencies or in the low frequencies. We don’t know that. That’s why the full picture of valence would also include the spectrum for positive, negative, and neutral valence. You can have high frequency pleasure, you can have low frequency pleasure, etc. So that kind of explains why there’s a tremendous diversity of possible mixed experiences even though ultimately they’d still come down to symmetry. Deep down, they can all still be explained with symmetry.

Now, endogenously generated symmetry, this is fascinating research. That when you have this “biorhythm coherence” you feel happier. And the way of computing biorhythm coherence is very related to musical consonance. Breathing entrained with heart rate variability is reported as giving rise to a just much, much better positive mood, and is one of the things that long-term meditation achieves. Meditation entrains these biorhythms and basically makes them interlock with one another. That is reported as giving rise to positive mood which is an interesting finding and very consistent with STV.

Here are just some quotes. Cool.

And you know, the heart palpitations. I mean, it’s similar to anxiety in that if you have like this usually regular metronome, and it’s failing, is generating these imperfections, that gives rise to unpleasant states of mind. I’m sure heart disease is terrible for your valence. Likewise, meditation is a wonderful tool for heart disease because it allows you to overcome those imperfections and still feel good despite the problem.

In terms of other endogenously generated symmetry, I will mention orgasm and flow. Orgasm is a powerful generator of endogenous resonance. It’s the entrainment of motor systems to near hallucinations, to synchronizing feedback processes across multiple functional networks. With an orgasm, there’s a deep, deep level of synchrony and symmetry across the nervous system. I highly recommend introspecting on this (not to get into your sex life or anything, though). I mean, it’s something you can actually pay attention to, and it becomes very obvious once you notice it. 

Likewise with flow, there’s this evidence that symmetry is deeply related to flow. Two physiological metrics for measuring flow are cortical muscular coherence and a degree of coupling between neural EEG waves and EMG oscillations of muscle activity. So, there’s also these interlocking patterns, lower information content, more symmetry. Yeah, it’s a strong predictor of flow. So like, hey, go figure flow is also symmetrical.

Okay, let’s get into the symmetry in the brain. So this is kind of the other projection you could take of the latent state. If you look at the central nervous system of high valence states, how does the valence show up? And, you know, meditation, like all over the place, basically pretty much any kind of meditation, if done for a long enough time, leads to some kind of EEG coherence. Whether it’s gamma coherence, delta coherence, or alpha coherence, depends on which kind of meditation you do. But they all generate some form of coherence, and coherence in EEG is intimately related with symmetry. I mean, basically, two signals are coherent when they’re both reflections of a shared signal through a reverb pattern, meaning that they’re encoding the same information just through a different filter, which is, again, deeply, deeply connected to symmetry. 

Here’s a fascinating study from 2019 that I recommend reading which to me was really stunning. It was stunning in just how clear the connection with the Symmetry Theory of Valence was. The study is about the EEG recordings of the first and second jhanas and the interesting patterns that emerged in them. One of them is this seizure-like activity. Now, seizure-like activity is three to five hertz, and it doesn’t have harmonic structure. I mean most seizures don’t have their harmonics together with them. But the type of seizure-like activity you see on jhanas does have harmonic structure. And the picture here is basically the Fourier transform of the independent components of the EEG recordings. You can see there’s a very clean 5.6 hertz signal, together with its harmonic of 11.23 hertz. This is kind of stunning. Why would this happen? And jhanas feel really blissful. Without the Symmetry Theory of Valence, this is just super surprising and strange. With the Symmetry Theory of Valence it’s like, “Oh, yeah, you’re, feeling a really great symmetrical attractor of your brain and sustaining it”. So that’s going to feel good. 

Even you know, ketamine showing high levels of a gamma coherence.

For 5-MeO-DMT, the only dataset I’m aware of, of EEG and 5-MeO-DMT, shows coherence across the spectrum, not only gamma coherence, but also beta coherence, and especially delta coherence. Again, why on earth? The Symmetry Theory of Valence would explain this. It would say, “Yes, this is expected”. Other theories might struggle a bit. Now, I’ve got to say that just because you have high coherence doesn’t mean it’s going to be high valence. We expect also very negative valence could also be high coherence. Except that when you have total coherence, then we expect that to be always positive valence. Again, it’s going to have that relationship because you could still have a high average coherence, but have half of your channels coherent in a certain frequency and half of the other channels coherent in a slightly different frequency. That might actually maximize dissonance. So just average coherence is not enough. You also need to tell whether it’s in harmonic structure or not.

Pleasure in the brain seems to be kind of this distributed effect that also from our point of view would mean it’s actually a whole brain phenomena. 

This is about what I was mentioning about the pleasure centers from our point of view. I mean, there’s this research of if you tried to synchronize clocks, and you tried to synchronize neurons, and you put them in a geometric grid. If it’s large enough, you’re not going to usually get full scale synchrony. You might have emergent patches of synchrony or traveling waves of synchrony. But if you also add these random connections across the network and reduce the synaptic path length, then you can unlock the ability for the entire network to enter synchrony. So we think of the pleasure centers as kind of these bridges that are, in a sense, lowering the average synaptic path length across your brain, and therefore enabling similar synchrony across the brain. And that’s the reason why we think the pleasure centers generally feel good when you activate them. 

Okay, getting to the end of the presentation. So I’ll just talk about a few near “enemies”. I put “enemies” in quotes, because we actually admire these people. They’re part of our research lineages. I think they’re a very, very key component of any good theory of consciousness. But I think when it comes to valence itself, there’s some explanations in the space that are really close to the Symmetry Theory of Valence, but they’re not exactly what we’re getting at. So there’s this whole account of computational efficiency. The brain likes computational efficiency, but in a sense, you still have to explain why the brain likes computational efficiency- what does this liking manifest as? We use this argument of “passing the bucket” which ideally your theory of valence should avoid. The theory should explain what valence itself is, not only when it gets triggered. These theories of computational efficiency, energy efficiency, we would claim, they’re telling you under what conditions positive valence gets triggered, but they don’t tell you what positive valence itself is. And that’s what the Symmetry Theory of Valence is getting at. 

So yeah, these are some of the issues with those, at least as complete theories.

Finally, okay, counter examples. There’s this whole theory I recommend reading called Neural Annealing (by Mike Johnson). But even very neutral energy that neither has harmony or dissonance, can still give rise to very positive feelings because it can give rise to this annealing process. And that’s actually what we believe is going on with psychedelics. Psychedelics gives you what Mike would call semantically neutral energy. And that gives rise to basically this entropic disintegration, a term from Robin Carhart-Harris and the entropic brain hypotheses, which then gives rise to kind of this search, or self-reorganisation that basically will settle on these basins of symmetry. And it’s those that feel good, not the energy that feels good. It is the end result, the attractor that it takes you to.

And this explains, I think, why even somebody can like hot sauce. Hot sauce is kind of this unpleasant stimuli, but it can lead to euphoria. It can lead to this heightened state of energy. If you introspect on the euphoria of hot sauce, it’s not the unpleasant pain in the mouth, it’s that it raises all of your energy, your entire amount of the intensity of your consciousness. You can then notice these resonant waves, and it is those resonant waves that feel good, not the hot sauce itself. So there’s this kind of a step that basically separates one from the other.

I’ll just very quickly, briefly describe one way we’re trying to test the Symmetry Theory of Valence. It is not the only way to test it. I would even argue that, you know, the argument that I here presented is itself a potentially strong argument. But ideally, you know, we generate novel predictions. And this is one of them, which is that we basically expect that the very positive states of consciousness will have a harmonic relationship, basically a consonant relationship between the brain harmonics. Yeah, using the work of Selen Atasoy.

This algorithm of quantifying the amount of consonance in brain harmonics, which is something we were working with, and hopefully will get resolved soon.

We anticipate that, again, if this is true, the Symmetry Theory of Valence would be validated. If it’s not, it doesn’t invalidate it, because there’s many ways in which it can manifest. But when you have harmonics that are in a consonant relationship with each other, and those are the main drivers of your experience, we expect that to be pleasant.

That is, euphoric.

Whereas, when you have harmonics that are dissonant with each other, they generate these intense beating patterns. So we expect that to be described as unpleasant. Again, we don’t know, but we want to check if this is true. 

Just a couple testable predictions based on this, which is that we expect psychedelics to enhance the range of valence. Basically, psychedelics enhance energy across the board. Just all of the harmonics have more energy. We expect that some of those combinations will be just very consonant and reported to be very pleasant, some of those will be very dissonant, reported to be unpleasant. Then SSRIs, there’s a lot of research on SSRIs and their blunting effects. They cut the extremes of valence. So, we expect when it comes to harmonics that the SSRIs will be more noisy, less consonant, less dissonant. MDMA, we expect it to be a stable attractor of a few resonant modes that are very consonant with each other. Stimulants would be kind of high frequency consonance. Opiates would be low frequency consonance. Again, this idea that you can be in a good state leaves underdetermined whether there are symmetries in the high frequencies or the low frequencies, and this would disentangle these types of mixed experiences.

These are the last two or three slides which is kind of a case study which is SSRI’s. Roughly speaking, we interpret them as being noise inducers which is why things like orgasm on SSRIs are less intense. Crying is hard. I mean, crying itself is a kind of a dissonant and sometimes consonant, kind of resonant state. On SSRIs you feel kind of spaced out and music enjoyment goes down. So yeah, the way we think of SSRIs is that they’re almost kind of like listening to a white noise machine along your life, so it’s gonna cut off the extremes. It’s gonna blunt both very positive and very negative valence, and it’s gonna just kind of center you in neutral valence.

Whereas psychedelics, they basically kind of purify and intensify your harmonics. And in that sense, you get to have more pleasant and more unpleasant states and both extremes.

Just to remind you: introspect. I compel you, next time you’re on a psychedelic having a mystical experience, introspect on the quality of space and time. I suggest that you will probably be experiencing these kinds of beautiful ripples that are in a harmonic relationship to each other. Please email me if this is true or not true. But that’s the experience so far. And that’s the reason why this can feel so amazing. 

The future of mental health, ideally, would be that we can identify, “what are the sources of dissonance in your nervous system?” and then find the shortest path to the smallest change possible that will give rise to sustainable consonance in your nervous system. Whether this is going to be with meditation, a psychedelic session, or yoga, or biofeedback will be person-specific. There’s probably a shortest path from a highly dissonant dysfunctional state to a sustainable consonant state for each person.

And with that I just want to say thank you to other people in the team of QRI. And thank you, Robin, Shamil, and all of you guys for attending this presentation. And to the Centre for Psychedelic Research for hosting this presentation.

Thank you so much.


* BART sound, Baby Crying, Baby Crying w/ Reverb

** Consonance – Noise – Dissonance – Mixed Spectra


Special Thanks to: Mike Johnson who initiated this research direction and has been deeply involved in it for years. To Andrew Zuckerman, Quintin Frerichs, Kenneth Shinozuka, Sean McGowan, Jeremy Hadfield, and Ross Tieman for their contributions to the current work this year. To everyone in the team for their help, support, and love. To our donors for their incredible help. And to you, dear reader. Thank you!

The QRI Ecosystem: Friends, Collaborators, Blogs, Media, and Adjacent Communities

The Qualia Research Institute has the vision of a world free from involuntary suffering in which conscious agents are empowered to have full control over their lived experiences. Its mission tackles this objective by combining foundational research on consciousness with a focus on explaining the mathematical properties of pleasure and pain for a full, formal account of valence.

By relating our mission to existing memeplexes, we could perhaps accurately describe the ethos of QRI as “Qualia Formalist Sentientist Effective Altruism“. That’s a mouthful. Let’s break it down:

  • Qualia Formalism refers to the notion that experience has a precise mathematical description that ties it with physics (for a more detailed breakdown see the Formalism section of the glossary).
  • Sentientism refers to the claim that value and disvalue are entirely expressed in the nature and quality of conscious experiences. In other words, that the only reason why states of affairs matter is because of the way in which they impact experiences.
  • Effective Altruism refers to the view that we can aspire to do the most good we can rather than settle for less. If you examine the actual extent to which different interventions cash out in terms of reduction in suffering throughout the world, you will notice that they follow a long-tail distribution. Thus, research on how to prioritize interventions really pays off. Focusing on the top interventions (and being willing to spend extra time digging for even better ones) can multiply your positive impact by orders of magnitude.

We could thus say that people and organizations are more or less aligned with QRI to the extent that they are aligned with each of these notions and their combinations thereof. More so, QRI also values the practice of rational psychonautics and the study of one’s own mind with meditation – hence we also include lists of rational psychonauts and great dharma teachers.

Find below the list of people and organizations that have a significant degree of alignment with QRI on each front. We also include a list of blogs and websites from readers of our work, which is meant to incentivize community-building around the aforementioned core ideas.

Format:

Name of Person/Organization – Blog/Website/Media [if any] (Representative Post of the Author- Sometimes Not from Their Primary Site [if any])


QRI Canon

Qualia Research Institute – QRI (Glossary)

Michael Edward Johnson – Open Theory (Neural Annealing)

Andrés Gómez Emilsson – Qualia Computing (Wireheading Done Right)

Current and Former QRI Employees and Collaborators Who Write About QRI Topics

Romeo Stevens – Neurotic Gradient Descent (Core Transformation)

Quintin Frerichs – The Youtopia Project (Wada Test + Phenomenal Puzzles)

Andrew “Zuck” Zuckerman – andzuck.com (Super Free Will)

Kenneth Shinozuka – Blank Horizons (A Future for Humanity)

Wendi Yan – wendiyan.com (The Psychedelic Club)

Jeremy Hadfield – jeremyhadfield.com (How to Steal a Vibe)

Elin Ahlstrand – Mind Nomad (Floating Through First Fears)

Margareta Wassinge and Anders Amelin – Qualia Productions (When AI Means Advanced Incompetence)

List of current and former QRI collaborators and volunteers not listed above (in no particular order): Patrick Taylor, Hunter Meyer, Sean McGowan, Alex Zhao, Boian Etropolski, Robin Goins, Bence Vass, Brian Westerman, Jacob Shwartz-Lucas.


People and Organizations that Advocate for Sentientism and the Elimination of Suffering

David Pearce – Hedweb.com (The Hedonistic Imperative)

Manu Herrán – manuherran.com (Psychological Biases that Impede the Success in the Reduction of Intense Suffering Movement)

Jonathan Leighton – jonathanleighton.org (Why Access to Morphine is a Human Right)

Magnus Vinding – magnusvinding.com (Suffering-Focused Ethics: Defense and Implications)

Robert Daoust – robert.algosphere.org (Review of Precursor Works)

Jacob Shwartz-Lucas – Invincible Wellbeing (Pleasure in the Brain)

Algosphere Alliance – algosphere.org (Vision)

Organization for the Prevention of Intense Suffering (OPIS) – preventsuffering.org (Cluster Headaches and Potential Therapies)

Sentience Research – sentience-research.org (Algonomy)

People and Organizations Aligned with Qualia Formalism

Giulio Tononi – integratedinformationtheory.org (Phi: A Voyage from the Brain to the Soul)

Steven Lehar – slehar.com (Harmonic Resonance Theory)

Jonathan W. D. Mason – jwmason.net (Quasi-Conscious Multivariate System)

Johannes Kleiner – jkleiner.de (Mathematical Consciousness Science)

Dan Lloyd – Labyrinth of Consciousness (The Music of Consciousness)

Luca Turin – A Spectroscopic Mechanism for Primary Olfactory Reception (The Science of Scent)

William Marshall – Google Scholar (PyPhi)

Larissa Albantakis – Google Scholar (Causal Composition)

Models of Consciousness Conference – models-of-consciousness.org (YouTube channel)

People and Organizations Aligned with Effective Altruism

Nick Bostrom – nickbostrom.com (What is a Singleton?)

Anders Sandberg – aleph.se (Uriel’s Stacking Problem)

Toby Ord – tobyord.com (The Precipice)

80000 Hours – 80000hours.org (We Could Feed All 8 Billion People Through a Nuclear Winter)

Future of Humanity Institute – fhi.ox.ac.uk (Publications)

Future of Life Institute – futureoflife.org (AI Alignment Podcast: Identity and the AI Revolution with David Pearce and Andrés Gómez Emilsson)

Center on Long-Term Risk – longtermrisk.org (The Case for Suffering-Focused Ethics)

Rethink Priorities – rethinkpriorities.org (Invertebrate Welfare Cause Profile)

Happier Lives Institute – happierlivesinstitute.org (Cause Profile: Mental Health)

Effective Altruism Forum – forum.effectivealtruism.org (Logarithmic Scales of Pleasure and Pain)


Rational Psychonautics

Steven Lehar – slehar.com (The Grand Illusion)

James Kent – psychedelic-information-theory.com (The Control Interrupt Model of Psychedelic Action)

Alexander Shulgin – Shulgin Research Institute (Phenethylamines I Have Known And Loved)

Thomas S. Ray – Breadth and Depth (Psychedelics and the Human Receptorome)

Matthew Baggott – Beyond Fear: MDMA and Emotion (MDA and Contour Integration)

Psychonaut Wiki – psychonautwiki.org (Visual Effects)

Psychedelic Replications – reddit.com/r/replications (Best of All Times Replicationsspecific floor tile example)

Great Dharma Teachers

Daniel M. Ingram – Integrated Daniel (No-Self vs. True Self)

Leigh Brasington – leighb.com (Right Concentration)

Shinzen Young – shinzen.org (The Science of Enlightenment)

Culadasa – culadasa.com (Joy and Meditation)


QRI Friends and Supporters

Ryan Ferris and James Ormrod – The Good Timeline  (5-MeO-DMT, Paradise Engineering)

Adrian Nelson – Origins of Consciousness (Consciousness Blindness in Science Fiction)

Alex K. Chen – Quora (What are the long term effects of Adderall, Dexedrine, or Ritalin use?)

Andy Vargas – Neologos (Praxis for Open Individualism; Purpose Statement)

Tyger Gruber – tygergruber.com (The Show)

Jacob Lyles – Jacob ex machina (Building a Better Anti-Capitalism)

Adjacent Communities, Organizations, and Allies

Scott Alexander – Slate Start Codex (Relaxed Beliefs Under Psychedelics and the Anarchic Brain)

Geoffrey Miller – Primal Poly (The Mating Mind: How sexual choice shaped the evolution of human nature)

Zvi Mowshowitz – Don’t Worry About the Vase (More Dakka)

Sarah Constantin – Multiple websites: 12, 3 (More Dakka in Medicine)

Scott Aaronson – scottaaronson.com/blog/ (Why I Am Not An Integrated Information Theorist)

Gwern – gwern.net (Iodine and IQ Meta-Analysis)

Venkatesh Rao – Ribbonfarm (Why We Slouch)

David Chapman – meaningness.com (Romantic Rebellion)

Atman Retreat – atmanretreat.com (FAQ)

Foresight Institute – foresight.org (YouTube Channel)

Convergence Analysis – convergenceanalysis.org (List of Works)

Simulation Series – About (YouTube Channel)

Consciousness Hacking – cohack.org (blog posts)

HeartMath Institute – heartmath.org (Chapter on Coherence)

The Wider World of People Who are Friends and Acquaintances of the QRI Ecosystem

Note: I asked (on social media) our readers to share their blogs and personal sites with us. Some of these links are very aligned with QRI and some are not. That said, together they represent a good sample of the memetic ecosystem that surrounds QRI. Namely, these links can be taken as a whole to be suggestive of “the memetic ground upon which QRI is founded”. Please feel free to share your blog or personal site in the comment section of this post.

Jack Foust – Welcome to the Symbolic Domain

Scott Jackisch – Oakland Futurist (Art as a Superweapon)

Maurits Luyben – Energy and Structure

Anonymous – deluks917 (What does ‘Actually Trying’ look like?)

Sameer Halai – sameerhalai.com (Toilet Paper Shortage is Not Caused by Hoarding)

Yohan John – neurologism.com (Some Wild Speculation On Goodhart’s Law And Its Manifestations In The Brain)

Jamie Joyce – The Society Library (Deconstructing the Logic of “Plandemic”)

João Mirage – YouTube Channel (The Mirror of the Spirit)

Natália Mendonça – Axiomatic Doubts (What Truths are Worth Seeking?)

Dustin Ali Francis Janatpour – Tales From Samarkand (The Inspector and the Crow)

Zarathustra Amadeus Goertzel – zarathustra.gitlab.io (Garden of Minds)

Duncan Sabien – Human Parts (In Defense of Punch Bug)

Brenda Esquivel – Abanico de Historias (La Reina Tamar y el Pájaro Condenado)

Vishnu Bachani – vishnubachani.com (Latent Possibilities of the Tonal System)

Martin Utheraptor Duřt – utheraptor.art (Psychedelic Series)

Qiaochu Yuan – Thicket Forte (Monist Nihilism)

Jedediah Logan – Medium Account (Coping with Death During the COVID-19 Crisis)

Eliezer da Silva – eliezersilva.blog (Prior Specification via Prior Predictive Matching)

Cassandra McClure – Lexicaldoll (On Save States)

Gaige Clark – mad.science.blog / Querky Science (The Phoenix Effect)

Ben Finn – optima.blog (Too much to do? Plan your day with Hopscotch [longer])

Michael Dello-Iacovo – michaeldello.com (How I Renounced Christianity and Became Atheist)

Robin Hanson – Overcoming Bias (What Can Money Buy Directly?)

Katja Grace – meteuphoric.com, Worldly Positions, AI Impacts

Mundy Otto Reimer – mundyreimer.github.io (On Thermodynamics, Agency, and Living Systems)

Khuyen Bui – Medium Account (Beyond Ambition)

Jessica Watson Miller – Autotranslucence (Art as the Starting Point; Becoming a Magician)

Aella – knowingless.com (The Trauma Narrative)

Jacob Falkovich – Put a Number on It (The Scent of Bad Psychology)

Javi Otero – iawaketechnologies.com (Fractal Entrainment: A New Psychoacoustic Technology Inspired by Nature)

José Luis Ricón – Nintil

Eliot Redelman – BearLamp

Tee Barnett – teebarnett.com (Are you a job search drone?)

Juan Fernandez Zaragoza – filosofiadelfuturo.com (Pandemia de Ideas)

Eric Layne – (The Antidote to a Global Crisis)

Kazi Adi Shakti – holo-poiesis.com (Beyond Affirmation and Negation)

Pushan Kumar Datta – kaiserpush1 (Ramayana and Cognition of Self)

Yan Liu – Inflection Point (Seeing a World Unshackled from Neoclassical Economics)

Joseph Kelly – (Entrepreneurship is Metaphysical Labor)

Logan Thrasher Collins – logancollinsblog.com

Malcolm Ocean – malcolmocean.com (Transcending Regrets, Problems, and Mistakes)

Jesse Parent – (Why ‘Be Yourself’ is Still Excellent Relationship Advice)

Milan Griffes – Flight From Perfection (Contemplative Practices, Optimal Stopping, Explore/Exploit)

Cody Kuiack – cosmeffect.com (The Holomorphic Self – Meditations)

Daniel Eth – thinkingofutils.com (Quantum Computing for Morons)

Brian P. Ellis – brianpellis.net (Refuting Dr. Erickson and Dr. Massihi)

John Greer – johncgreer.com (The Three Buckets)


Finally: List of Other Relevant Lists

Effective Altruism Blogs – eablogs.net

LessWrong Wiki – List of Rationalist Diaspora Blogs

Effective Altruism Hub – effectivealtruism.org (Resources)

Open Individualism Readings – r/OpenIndividualism (Wiki Reading List)

Phenomenal Binding Resources – binding-problem.com

Physicalist Hotlinks – physicalism.com/physicalist-hotlinks

QC Coronavirus Edition: Preventing Pandemics by Living on Toroidal Planets and Other Cocktail Napkin Ideas

Here is what we’ve gotta do.

I want every strategy we’ve got on Near Earth Object Collision, OK?

Any ideas, any programs, anything you’ve sketched on a pizza box or a cocktail napkin…

Armageddon (1998 film, when NASA realizes that there are 18 days left before the asteroid hits the Earth)

This Whole Thing

On January 20th someone shared, in a facebook group that I’m a part of, four facts about an emerging viral infection in China: (1) high death rate, (2) high contagion rate, (3) long incubation periods, and (4) the fact that it appeared uncontained. Despite the (at the time) relatively low number of cases, those four facts did not seem to paint a pretty picture of what was about to happen.

This was immediately alarming to a lot of people in my circles, and for good reason. Matthew Barnett, Justin Shovelain, Dony Christie, and Louis Francini sounded alarms as early as mid-January, and the rest of the EA and rationalist cluster followed suit. It makes sense people in this cluster would be concerned early on, as many of them have looked at global catastrophic risk scenarios for years, and were already well aware that the world was unequipped to deal with an infectious disease with all of the above four properties. Pandemic preparedness programs have so far relied on luck. For instance, in his 2015 TED talk “The next outbreak? We’re not readyBill Gates uses as an example the 2013 Ebola outbreak: “The problem wasn’t that there was a system that didn’t work well enough. The problem was that we didn’t have a system at all.” Accordingly, that particular outbreak didn’t become a disaster because of sheer luck: the disease only becomes contagious when you are already very sick and it didn’t hit a major urban area, so containing it was possible. But this time around we don’t seem to have the same luck.

Since, I’ve seen many thought leaders I respect succumb to focusing on this topic: Robin Hanson, Eliezer Yudkowsky, Paul Graham, Tyler Cohen, Sarah Constantine, Scott Alexander, Scott Aaronson, Joscha Bach, Ryan Carey, William EdenRobert Wilbin, etc. etc. Not to mention the way these people are publicly responding to each other and building a parallel narrative on a higher level of complexity than most everybody else****. These and many other well respected intellectuals have been going on and on about the situation for over a month now. An exponentially growing curve in its early stages may not be alarming to most people, but it certainly was to people like this (Ps. 3Blue1Brown, Kurzgezagt, and Mark Rober also recently joined the conversation).

89891338_10158153144883554_5533215167824789504_n

Image by Evan Gaensbauer (March 2020 Dank EA Memes banner)

This all adds up to a vibe of countdown to Armageddon: “X days until hospitals are overwhelmed, Y days until a million people die, Z days until a vaccine will be found”. In line with this perceived, if not frighteningly real, urgency, we’ve seen countless facebook groups, subreddits, and forums scouting for novel ideas and projects to help above and beyond what the governments of the world are already doing (e.g. Covid19RiskApp, Give Directly Response, Covid Accelerator [of technology to decelerate the spread [possibly a terrible or brilliant branding]], List of Predictors, and Corona Variolation).

march_19_2020_spread_pandemic

As of March 20 2020

I personally gave a lot of thought to pandemics several years ago (in college I was on the fence between working on pandemic prevention and consciousness research as a career), so my immediate thought when learning about the virus and its properties was “we are screwed, this can’t be contained with how the world is currently set up”. While containment might have been possible at the very beginning with some luck, it very quickly becomes unmanageable. That said, I’d like to explore here ways in which the world could be realistically modified in order to contain, mitigate, and ultimately reverse the spread of novel contagious diseases including this one. After all, the WHO director general said on March 9th: “The rule of the game is: never give up.” So, well, let’s give it some more thought. I hence offer my ‘sketches on a cocktail napkin’ type of ideas in case they find any application:

Introduction

Let us start by breaking down “social networks” into (1) contact networks, and (2) information networks:

  1. Contact networks are weighted undirected graphs where each node is a person and each edge encodes the frequency and intensity of the contact between the people it connects.*
  2. Information networks are weighted directed graphs that encode the amount of information transmission that there is between pairs of people. To a large extent, contact networks are subsets of information networks.**

Contact networks are what matters for modeling infectious disease transmission. Despite the constitutionally granted freedom of assembly, one can posit that if the risks to the public are high enough, it is justified to place some constraints on the nature and properties of contact networks. In a free society that truly grasps the danger of pandemics and is determined to squash them at the very beginning, contact networks might require some degree of top-down control. Perhaps, if we are serious about future pandemic prevention, we could re-conceptualize freedom of assembly as pertaining to information, rather than contact, networks.***d3297191270ea5bca8db652e977a6d57

So in what ways could a contact network be pandemic-safe? As an intuition pump for what I’ll be discussing further below, I’d like you to consider what it might be like to live in the original “HaloRingworld (and Ringworld too). Assume that unrestricted travel in Halo is limited to land roaming with a maximum speed, and that in order to use a spacecraft or tube across an arc of the circle, you need to be thoroughly tested and quarantined in-between. With these constraints, we would naturally infer that the structure of the contact network of the people in this world would be embedded in the ring itself. Meaning that if an infectious disease originates somewhere on the Ringworld, containing its spread would be as easy as blocking movement on two small fronts around the epicenter of the outbreak. This even allows you to control and ultimately fully suppress diseases with long incubation periods. It is a matter of estimating how long the incubation period is, and quarantining the entire region of “furthest possible transmissibility”.

More so, given the overall circular geometry of the world, after a brief period of quadratic growth of the epidemic (as concentric circles expand around the epicenter)  one would expect to see a threshold after which there is merely linear growth in the number of cases as a function of time!

Network Geometry as a Containment Strategy

To a first approximation, the single most important problem to overcome for containment is the exponential growth of the early stages of an outbreak. Of course in some cases an exponential growth is not itself the problem: and R0 = 1.001 leads to exponential growth, but it is still so slow that it can be easily dealt with. Likewise, a sub-exponential growth can still be unruly, as in a polynomial growth with an exponent of 20. But to a first approximation, I would argue that if you can get rid of exponential growth you can manage an outbreak. The example above of a Ringworld shows that exponential growth in contact networks can be slowed all the way down to linear growth at relatively early stages. Similarly, “thin” toroidal planets would also enable easy containment of outbreaks (Anders Sandberg‘s amazing work on the physics of toroidal planets finally pays off! It remains to be seen when his work on stacking high-dimensional polytopes finds real-world applications).

torusdonut2-thumb (1)

Toroidal World

But we don’t have to go all the way to high sci-fi scenarios to encounter sub-exponential growth of infections in human contact networks. You see, the black death happened at a time when the contact network of humanity had a quasi-quadratic structure at the largest of scales. Villages almost certainly had a scale-free structure (e.g. the priest touching everyone once a week and the lone serf perhaps only interacting with two people a week), but once you look at the structure at scales above the village, you would find routes between neighboring villages weaving a planar graph with a 2D Euclidean geometry. The trade routes, though, provided an exception, and in the end they turned out to be key for the spread of the plague. That said, in the absence of cars, trains, or airplanes, the maximum speed of transmission was seriously limited. Historians can tell when different parts of Europe got the plague because it really took a long time to spread; we are talking about years rather than weeks.1920px-1346-1353_spread_of_the_Black_Death_in_Europe_map.svg

So imagine having a contact network structure characteristic of the medieval times, but with an information network structure akin to the ones we currently have. Then controlling the black plague would be a piece of cake! You would simply need to close central trade routes, track down which villages are already infected, and put a perimeter around them.

Ok, so how do we generalize this idea to the modern times in a realistic way? I think we should perhaps think outside the box here. Remember, the core intention here is to make the spread of an infectious disease not behave in an exponential way at the beginning so that we can “segment out” the part of the network affected (i.e. quarantine) because the “surface area” of the region is not very large. Now, most analysis of disease spread on networks focus on analyzing how realistic-like network features affect disease spread. For example, clustering coefficients, the steepness of the slope of power law networks, the distribution of in-betweenness centrality of the nodes, and so on.

In a perhaps high-modernist style approach to network engineering, one can ask how the spread of a disease would change depending on alterations we could make to the network. The simplest real world case is the reasoning behind adding travel restrictions, which aim to block the spread between very large clusters (i.e. countries) and the closing of schools, universities, and large gatherings, which decrease the interconnectivity of each region of the network. A slightly more sophisticated version of this approach would be to come up with a “Pandemic Klout Score” for each person based on the their “network influence” and pay them to quarantine early on during an outbreak.

I actually worked at Klout as an intern in 2010, and my contributions were mostly on the (unfortunately slightly evil because it’s marketing) following problem: “How do you maximize the spread of a commercial campaign by giving free products to people?” Klout had what they called “perks” which was how they made money. They had contracts with other companies to give free products to “influencers” so that they talked about the perks on their social media accounts. To maximize the spread of a commercial campaign meant to distribute perks in such a way that the largest number of people made mentions of the campaign on their networks (including people who didn’t receive the free products). This is how they measured success- at least when I was there- and what the companies paid them for.

The “basic approach” would be simply to distribute the perks to people with the highest Klout scores, with the additional constraint that those people were influential on the relevant topic (e.g. if you had a popular Twitter account about “beauty and personal care” you might be a prime candidate to get a free “anti-aging sunscreen stick”, or whatever) . But since you can’t actually, you know, entice Justin Bieber (the person with the highest Klout score for several years) with a free Virgin America flight and expect him to either care or talk about it on his Twitter feed, the problem ends up being substantially more complex than just “give people with high Klout the free products”. I am under an NDA about the specific algorithms and research I conducted there. But I mention this because the problem of pandemic prevention could in some sense be thought of as the inverse of the problem Klout was trying to solve. Namely, how you use the node features of the network in order to minimize the spread of a contagious disease. The low-hanging fruit idea here can be to simply allot money to pay people with high Pandemic Klout Scores to stay home or cut their human touch in half whenever an outbreak arises. I would expect this to be significantly better at reducing the reproductive rate of a contagious disease than choosing people at random (or even just based on how many people they interact with on a daily basis).

That said, given the risks and costs involved with pandemics, especially in the long term in light of bioterrorism, we should not close off the possibility of making drastic changes to humanity’s contact network for the sake of our collective wellbeing. That is, merely asking some people to stay home may not be enough. We should contemplate what it would really take to be able to fully contain any future pandemic.

In terms of large-scale network geometry rather than just dealing with one node at a time, perhaps the key point to make is that we should really not fetishize and romanticize the “six degrees of separation” that results from the small world-like structure of the modern human contact network. Yes, “it’s a small world after all“, but you forgot to mention “and that’s what will get us all killed in the end.” Let’s not allow misguided network idealism to murder grandma. We need to make the contact network a large world, and save the small world exclusively for the information network.Screen-Shot-2012-04-05-at-19.26.38

Intuitively, it is precisely the small world-like property of our contact network that allows us to: meet many new people on a regular basis, collaborate with people around the world, be able to attend large gatherings, raves, and festivals, and travel care-free across the planet. Meaning, most people might think that changing the contact network structure to make it pandemic-proof would come at the cost of sacrificing what makes society so interesting and worth living in. I would disagree. I think that such a line of thinking is just the result of a failure of the imagination. We can, I posit, have contact networks that allow you to do all of that and yet be pandemic-proof. I will argue that with intelligent top-down network engineering you can in fact achieve this. Here is my case:

Scale-Dependent Geometry

The main concept that one needs to understand for my argument is that the options for large-scale network structure go far beyond the textbook examples of small worlds, scale-free, random, planar graphs, etc. In fact, one can create all kinds of fascinating hybrid networks where the properties vary by region and scale. The examples I am about to show you play with the notion of scale-dependent geometry. Meaning that the network properties depend on the number of interconnected nodes that you are considering. In particular, I’ll break down networks in terms of their micro (1 to 1,000 nodes), meso (1,000 to 1,000,000 nodes), and macro (1,000,000 to 1,000,000,000 or more nodes) structure:

QLE_ELQ

QLE and ELQ

QLE

The first example is one where the structure of the network leads to quadratic spread on the micro level, linear spread on the meso level, and exponential spread on the macro level. We achieve this by having the nodes arranged along a rectangular grid at the micro level. As one zooms out, the grid hits a limit on two fronts so that the advancement of an infection disease will start growing linearly as it only has two directions to grow in (for the sake of symmetry you can glue the two fronts to make a tube, for a meso network structure akin to that of a toroidal planet). Finally, at the largest scale this network looks like a binary tree, where the growth can reach an exponential rate.

The same scheme will apply to all of the following networks. That is, the letters indicate the ordering of the types of growth for the micro, meso, and macro scale. What I will instead focus on is explaining the advantages of these structures. In this case- the case of QLE- the primary advantage is that the spread can be entirely contained by cutting connections around the epicenter. And the best part is that even if you hit the exponential scale (i.e. you start spreading from “one arm to another”) you will still have long periods of linear growth as each “arm” will grow linearly, so cutting it will remain an option at any point. The “surface area of the spread” will remain tiny relative to the size of the network.

ELQ

A very nice property of this network is that you can have “villages” of up to 1,000 people where everyone can interact with and touch each other. Within each of these villages you have super efficient in-person information transmission and contact hedonism without restrictions. Then each of these villages would be connected to two neighboring villages, perhaps not unlike how kids in grade school often make friends with other kids in the grades immediately above and below (and only rarely with grades that are further apart). The spread of disease would very quickly engulf each village, but thankfully that would be it. After that you would have a very slow village-by-village take-over that could be stopped by ‘cutting’ the contact channels between two pairs of villages (or four if you started at an intersection of the macro structural grid). More so, you could conceive of a “conveyor belt” approach where every month half of the village moves in one direction while the other one stays put. This way over the course of years you would still be able to get to know tens of thousands of people, party like crazy in raves touching everybody, and be able to retain long-term friendships by coordinating with them to either move or stay. And you could do all of this while living in a pandemic-proof world!

LQE_EQL

LQE

This one is perhaps the least viable because it relies on most persons only having contact with two people. That said, the spread would start very, very slowly, and so it might be ideal for the worst possible pandemics. At the macro level the network looks like high-dimensional cardboard boxes, where each “cardboard side” is glued at the edge with one or multiple other sides.

A “continuous” version of LQE could use hyperbolic geometry at the macro level, such as what you get when you sneak a pentagon here and there in an otherwise rectangular grid so that locally you have a square spread, which slowly turns into an exponential spread as you begin swallowing pentagons. (Or a few heptagons in a grid of hexagons).

EQL

This one is pretty similar to ELQ, and you can do pretty much the same things I mentioned about ELQ. The main difference is that this structure is safer at the macro level but riskier at the meso level. So if you expect diseases to be really really contagious, then this structure might prevent “the end of the world” but it might be somewhat susceptible to “pretty bad scenarios”, while ELQ works the other way around.

LEQ_QEL

LEQ

I find this network very interesting because to build it I had to come up with the idea of connecting lots of cycles of different lengths with each other by having them share nodes. You can also easily construct a network like this by starting with a scale-free network and replacing the edges with long chains of nodes.

QEL

This would perhaps be the steel-manned version of the toroidal or ring world we discussed in the introduction. Here the infections would spread first slowly at a quadratic rate, then quickly accelerate once you reach the edges of the planar graph you start in, and finally there is a massive linear bottleneck at the macro scale. It’s like Ringworld, but where you interact with people in an interlaced braided mesh embedded inside the Ringworld rather than only in its meager inner surface.

Because each of these examples contain a “linear bottleneck” at some scale, an outbreak of a disease would be easy to contain at some scale. Which network is ideal for which kind of disease will depend on things like its incubation period and its contagion probability. But any of these examples is vastly safer pandemic-wise than our current contact network.

Is Biology Doing This Already?

One thing this exercise has made me wonder is if perhaps our bodies are already using this kind of strategy. I mean, looking at QLE reminds me of the structure of blood vessels in the kidney and liver. It would make sense that evolution would identify great micro, meso, and macro network structures in order to give each organ appropriate contact networks at the scale that matters to conduct its function, while creating network bottlenecks at other scales for protection against pathogens and the spread of cancer. In contrast, the immune system would have every reason to maximize spread at the largest scale while having compartmentalized spread at the micro scale (example: Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality). Finding the sub-exponential chokepoints in the human body would, I posit, give us a new angle for understanding it more deeply.

Creating a Global Human Organism

If this analysis pans out, we could perhaps think of the challenge being presented to us by SARS-CoV-2 and future pandemics as a wake up call to “scale up the network-protective measures our bodies are taking to combat disease while maintaining functionality” all the way up to the structure of all of human society. Indeed, wouldn’t it be amazing if we coordinated to be a harmonious large-scale global organism?

Now, I am not saying we should simply adopt one of these network structures. They are just proofs of concept to show it is possible to have humanly-desirable properties that come with highly interconnected networks along with a linear (or at least sub-exponential) bottleneck at some scale. The bottleneck does not even need to be visible or detectable from the point of view of each individual!

Even if we cannot construct an ideal world from scratch, we could still try to bootstrap it from within our current world. To do so we have a number of options. I will mention two and then dive into them in greater depth. The first is the strategy of “network modification” and it consists of developing gradient descent algorithms that point us to the modification of the network that would maximize a scale-specific sub-exponential bottleneck. Of course this could lead to local minima, but we don’t care about achieving the best configuration, just the closest one that is “good enough”. The second approach is that of “network nucleation” to bootstrap a pandemic-protected contact network by connecting with other people who can prove that they do not have the disease. They could all get to know each other, and then submit a list of “people they would like to hang out with on a regular basis”. An algorithm would then optimize the network so that each person can hang out with as many others as possible while making sure the overall geometry of the network is desirable for disease contention. If lucky, we could even bootstrap this system all the way up to the entire planet, starting from a mixture of people who’ve demonstrably been quarantined for a long time and people who have already recovered from the disease. And since, of course, people would eventually get sick of hanging out with a restricted list of friends, they could periodically re-submit another list and the algorithm would take into account this dynamic so that the geometry can be stable over time.

My prediction is that the current strategies that are being used to reduce the spread of disease would show up as a tiny subset of the set of possible effective strategies, many of which are currently invisible- and in some sense inconceivable- to us. This is because, in part (as far as I know) nobody is thinking in terms of scale-specific network geometry. Also, little is known about the actual empirical structure of the human contact network. In this sense, removing super-spreaders or closing schools may be re-conceptualized as pointing in this direction, and yet perhaps may not even make the Top 10 list of best cost-effective strategies. This is because just removing high-degree nodes in a scale-free network won’t automatically prevent exponential growth; since exponential growth is the killer, making strategies directly targeted at it will probably be vastly more effective. Let’s investigate these strategies in more detail:

Option 1: Network Modifications

The first thing we should do is find what actual contact networks look like, so that we can identify the smallest possible modifications to them in order to create sub-exponential bottlenecks on some scale. I have not found a good study on this, since there really aren’t public datasets of “who is physically hanging out with whom”. Though, if you were to combine, perhaps, the datasets of USA’s NSA, UK’s GCHQ, Russia’s KGB, China’s MSS, cellphone location information, census responses, and commercial surveillance camera data you might be able to get a very decent version of it. In fact, there is reason to believe Israel is already in the process of constructing this dataset.

In the absence of contact network data, we can nonetheless learn from other social and information networks. In particular, the best research I’ve read about the macro-structure of complex networks comes from the lab of Jure Leskovec (I recommend watching his CS224W lectures from past years, which are all available online):

We study over 100 large real-world social and information networks. Our results suggest a significantly more refined picture of community structure in large networks than has been appreciated previously. In particular, we observe tight communities that are barely connected to the rest of the network at very small size scales; and communities of larger size scales gradually “blend into” the expander-like core of the network and thus become less “community-like.” This behavior is not explained, even at a qualitative level, by any of the commonly-used network generation models.

Lescovec et al. 2008, “Community Structure in Large Networks: Natural Cluster Sizes and the Absence of Large Well-Defined Clusters

As you see, large-scale analysis of real-world networks indicate that they are not adequately described by the classic textbook structures that are most well known. Rather, there seems to be a kind of “galactic shape” at the more macro scale, where there is a highly connected giant core of overlapping communities surrounded by loosely connected superstructures (nicknamed ‘whiskers’):

Given this structure (and assuming it generalizes to contact networks), one could divide the problem into two rough components: (1) how to you deal with ‘whiskers’?, and (2) what do you do about the ‘galactic core’? I do not have answers here, but I do think that having more people who are good at math and computer science think about this would be very good. For what is worth, I have the hunch that in particular the following two network analysis techniques will be useful to tackle this problem:

  1. Spectral Graph Theory: This is a set of techniques that can help us ‘see diffusion bottlenecks in graphs’ at a glance. For instance, these techniques reveal the presence of network “chokepoints” that create insulation in heat flow. Clearly heat flow does not behave in the same way as the spread of disease, but the similarity makes it worth highlighting.
  2. Discrete Differential Geometry: An emerging field that blends differential geometry with network analysis and has shown amazing applications for graphics which can help us ‘see the curvature and dimensionality of a network around each of its nodes’ at a glance. Note: As much as I love hyperbolic spaces, I must admit that from the point of view of early pandemic prevention living in a contact network with hyperbolic geometry is a terrible idea.

Flatten the Network!

One additional interesting approach for Option 1 would be to apply topological clustering techniques to the contact network so that we can identify the hubs with the least desirable network geometry and try to “flatten them”. And policy-wise, I might imagine that in the long-run we could improve the flattening of the contact network by encouraging people to use things like the Bumble app for dating, where you find people physically near you with whom you could form a healthy relationship.

Option 2: Network Nucleation

Green and Red Countries

Countries_Recognizing(Green)_Not_recognizing(Red)_Kosovo

Imagine green are virus free, red are virus uncontrolled, and grey have unreliable statistics. (This actual map is about something unrelated I’m not going to name; it is just used as an example of what the world might look like).

Joscha Bach predicts that in a couple months there will be “green and red” countries, meaning that the outbreak will be completely under control in some countries, and completely out of control in others. I’d also add “grey” to refer to “unreliable statistics”, as many countries might just choose to not monitor the situation. You can imagine what the travel restrictions may be between green, red, and grey countries, as green countries would not find it worthwhile (or at least not politically viable) to accept the risk of reigniting the spread. Grey countries may end up also avoiding red countries while not being allowed to enter green countries.

Speculatively, this would perhaps lead to a worldwide Sakoku phenomenon, but where rather than just Japan, we would have all of the countries of each color becoming economic and cultural blocks.

What I’ll describe below is a kind of generalization of this possibility. Namely, that the blocks don’t need to be country-based.

A very interesting question to ask is “what possible partitions of humanity could create sets of people for whom a green/red/grey dynamic would successfully create clusters of wholly virus-free people?” The existence of at least some greens opens up the possibility of:

Reversing The Pandemic

I address you tonight, not as the president of the United States, not as the leader of a country, but as a citizen of humanity. We are faced with the very gravest of challenges. The Bible calls this day Armageddon. The end of all things. And yes, for the first time in the history of the planet, a species has the technology to prevent its own extinction. All of you praying with us need to know that everything that can be done to prevent this disaster is being called into service. The human thirst for excellence, knowledge, every step up the ladder of science, every adventurous reach into space, all of our combined technologies and imaginations, even the wars that we’ve fought, have provided us the tools to wage this terrible battle. Through all the chaos that is our history, through all of the wrongs and the discord, through all of the pain and suffering, through all of our times, there is one thing that has nourished our souls and elevated our species above its origins, and that is our courage. Dreams of an entire planet are focused tonight on those 14 brave souls traveling into the heavens. May we all citizens of the world over see these events through, Godspeed, and good luck to you.

– Armageddon (1998 film, when the president of the US announces the plans to avert an asteroid that would destroy the earth) [See also: what if they don’t come back?]

Nucleating Whole Virus-Free Communities

The simplest way to create a virus-free community would be to think of verifiable self- quarantining as an investment. If you can prove you’ve been physically disconnected from everyone for 30 days, you would be let into a club for people near you who have done the same already. This could become a large set of people, especially if it turns out that cash handouts are insufficient for millions of people who might end up needing to work in a month or two and defy any kind of large-scale quarantine. Those who can afford (and prove!) that they’ve been diligently quarantining would be allowed in. For a stricter “inner set” there might be stricter criteria where you would need to submit an unfakeable biosample to prove you are not infected (which would be tricky but not impossible given pre-existing DNA databases like 23andMe). Then the algorithm would group you with a subset that you can realistically physically meet, and then allow you to make friends with them. Finally, as you submit a list of people you do want to hang out with long-term, the algorithm would run an optimization process to make as many of the people happy and return the curated list of people you could hang out with so that the network as a whole has convenient scale-dependent sub-exponential chokepoints. I know this sounds like a lot. And it is. But again, pandemics can be really bad. And we have the technology, so why not try?

In a way this idea is the complementary problem to “keeping the virus out of the general population”. In the latter you start out in a fully virus-free situation and try to keep it that way, while the former starts out in a highly contaminated population and tries to “spread health” from the standpoint of a verifiably healthy core. That is, how you create pockets of health in a virus-saturated general population and grow them as much as possible.

Another approach in this vein I can think of is to seed a location with an excess of people who already have immunity and cannot transmit. The people there who haven’t gotten the disease would in a sense be lucky to find themselves around people who won’t transmit it, and thus be blessed with spontaneous herd immunity. That said, the key sacrifice here would be the potential damage elsewhere, where herd immunity would be reached later due to the removed group of immune people. This and the previous approach incur the cost of having to associate with new people, and the relocation challenges would be a logistical nightmare. But perhaps worth doing.

Finally, another approach to this problem would be to use an app with a personality test that is hard to fake, so that only healthy people who score in the top 2% of both introversion and conscientiousness could join the club. It would tell you where to go live with other people who meet the same criteria, and to get a comprehensive test of all major transmissible diseases and treat those you have before relocation. Given the temperament selected for, everyone who becomes part of the community would be extremely diligent about not physically meeting people outside the group and follow the contact network prescriptions dictated by the algorithm. If this sounds like hell to you, well, perhaps it is not for you. But at least this way there would be some pockets of fully healthy people, and that would have a lot of value. (Cf. Rat-free Alberta).

To Summarize:

What are your options for modifying a network in order to remove (or at least tame) exponential growth? The one’s I’ve considered are:

  1. Remove nodes with a high “Pandemic Klout Score”
  2. Creating sub-exponential chokepoints:
    1. Option 1: Gradient descent methods:
      1. You make piece-meal modifications to the contact network one connection at a time in order to improve the prospects of the entire network.
      2. Each person would receive a set of options for mild modifications to their contacts so that whichever they chose would lead to an improvement of the network geometry.
    2. Option 2: Network nucleation:
      1. You create a criteria for what constitutes “infection-free” such as:
        1. Self-enforced quarantine on one extreme, and
        2. Provable DNA-matched tests on the other extreme.
      2. Allow people who qualify to meet each other.
      3. Everyone submits a list of people they’d like to hang out with.
      4. The algorithm would optimize the connections to make everyone happy and at the same time maximize the sub-exponential chokepoints of the network (such as by making it a planar graph with a high clustering coefficient, etc.).

Now, perhaps if all of this sounds insane and like too much trouble, there is always the option of, er, becoming comfortable with no human touch…

Future Cultures

A Religion of Abstinence of Human Touch

I know how hard it is, what is being demanded of us.

Especially in times of needs such as these, we like to be close to one another.

We understand care and affection in terms of human closeness and human touch. 

But at the moment the exact opposite is the case, and everybody really must understand that.

At the moment, the only real way of showing you care is keeping your distance.

– German Chancellor Angela Merkel, at a Nationwide TV Address (March 18 2020)

Have you ever noticed that it is possible to reproduce without any human touch? Artificial insemination conducted with robotic arms is not a far-fetched prospect. A further question is: can we do away with human touch entirely for all functions of life?

You don’t need to be anywhere to be everywhere.

– John C. Lilly

You may say: wouldn’t a community of touch-free individuals somehow lack the most basic of human qualities, i.e. interpersonal intimacy? I reckon that you would be wrong on more than one account. First of all, insofar as touch-based intimacy is based on endorphin and oxytocin release in conjunction with nervous system entrainment under the hood, there is no reason why one couldn’t engineer a brain-stimulation technology ecosystem so that people receive the same kind of physically, psychologically, and spiritually rewarding feelings of connection by merely acknowledging each other’s presence or synchronizing with each other’s brainwaves. Perhaps even you could achieve this despite doing away with technology, as the power of deep metta meditation would suggest. Perhaps we could all cultivate a loving temperament that embraces all of the universe of sentient beings. Here, the commitment to each other’s physical wellbeing is possible without sacrificing the emotional richness of communion; in principle they could be simultaneously satisfied. Alas, the evolutionary roots of human touch are deep, and trying to mess with them with humans as they currently are is far fetched. But just wait until a virus with 0.98 fatality rate and R0 = 6 is discovered and see what people are willing to do to survive.

This concludes my presentation of the cocktail napkin ideas I’ve considered so far to deal with pandemics. But I still have a couple more things to say about this topic, so I’ll take advantage of the soap box I’m standing on and add:


Now That The World Is Paying Attention

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From the 1998 film “Armageddon”

I’d like to draw your attention to the following highly relevant goals that the current crisis highlights:

1) We ought to recognize the existence of extreme suffering so that we focus our efforts on its prevention (asphyxiation is an example of extreme suffering, which is how people are dying of COVID-19).

2) Investigating what makes MDMA and 5-MeO-DMT so special and useful for treating PTSD (as people recover from the disease it will become apparent many experience PTSD associated with the episode – this will need to be addressed on a massive scale).

3) Get factory farms banned (for real, they are the breeding grounds of future pandemics – and they of course also cause the bulk of easily preventable suffering, so there is that too. Every animal product you put on your plate is a probabilistic pandemic on its way. Sorry!).

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Let’s make the best of this situation (More Dakka!)


A Few Final Thoughts

The Framing Effect

Recall the “Framing Effect” – the cognitive bias where we prefer an option when the problem is framed in a certain way, and a different option when it’s framed differently even though the corresponding options in each framing are of equal expected value.

I worry a lot of the people in my friend network, and in fact worldwide, might be falling prey to the framing effect for the coronavirus situation:

Here is how the “containment vs. mitigation” problem is being “framed” right now (assume 5 million people will die worldwide if nothing is done, but you can choose to invest your resources on ‘containment’ or ‘mitigation’):

Option A: 10% chance 0 people die (i.e. successful containment), and 90% chance 5 million people die.
Option B: 100% chance 4 million people die.

Clearly option A is more ‘heroic’. Alas, it is the one that leads to more expected deaths.

Now consider the alternate framing that might make you feel differently about the options:

Option A: 10% chance of saving 5 million people (i.e. successful containment) and 90% of saving nobody.
Option B: 100% chance of saving 1 million people (i.e. mitigation prevents many deaths).

In both cases option B is much better by a huge margin. In fact by an expected number of 500,000 people saved. Yet when framed in the first way option A seems a lot more attractive. Why? And should we try to get rid of this bias?

Of course in the real world you don’t have to choose between A and B entirely. You can try to do both containment and mitigation. But you *do* need to choose how to allocate resources, and I believe this framing issue does actually come up in our current situation.

I do want to say that, as Robin Hanson suggests, if we are doing the containment strategy we need buy-in from the population. Some personally costly and dramatic public display of commitment from many people would be useful. I am personally very happy to commit in public to hard-core quarantine if it’s ethically necessary.


Social Withdrawal and Behavioral Enrichment

Social distancing is painful because we are all opioid addicts, namely, addicts to the endogenous opioids released when socializing. With a quarantine in place, we can anticipate that people who are on the threshold of being depressed might cross that threshold as an effect of reduced in-person socializing. Likewise, we can anticipate collective health decline at a statistical level due to reduced exercise, sunlight exposure, and sensory diversity (cf. white torture).*****

Possible solutions? Besides being very bullish on at-home exercise routines and HEPA filters, I would also point out the following. I think that we should not be afraid of comparing ourselves with other animals. Bear with me. Humans, not unlike domestic dogs and cats, benefit from being exposed to a wide variety of novel sensory inputs. If you enjoy scents, for example, it would be advisable to order a set of essential oils or perfume samples in order to trick your brain into thinking you are exploring a larger area than you are. Apparently, for example, big cats in captivity are more engaged and less depressed when you spray Calvin Klein perfumes on their territory. Alternatively, if scent is not something you care about, think of perhaps increasing the repertoire of visual art, dance, food, touch, and music you are exposed to on a daily basis. This, I suggest, will help you keep depression away (for a while longer).

Caption: Just a little bit of behavioral enrichment for you! 🙂

Finally (self-promotion ahead), if you have time on your hands, and you’ve been meaning to dive deeper into Qualia Computing, this might be your chance. I’d suggest you start out with the following three resources:

  1. Top 10 Qualia Computing Articles
  2. Glossary of Qualia Research Institute Terms
  3. Every Qualia Computing Article Ever

And if you are really hard core, feel free to reach out to the Qualia Research Institute to help with volunteer work. Also we are going to be doing virtual internship cycles in April, May, and June, so you can stay home and safe and still collaborate with us. But shh! It’s a secret! (Wait, how come it’s a secret but you now know about it? Well, because you’ve scrolled all the way here, that’s some commitment!).

The End


* A more accurate representation might require the use of directed edges to encode asymmetrical contact relationships. For example: the cleaning crew of a hotel might be more exposed to the guests than the guests are exposed to the crew. Also, when two people who have very different habits of hygiene meet, the cleaner person is more likely to get the short end of the stick transmission-wise.

** It is worth pointing out for information networks the “degree of interaction” between nodes is extremely skewed. You may have a thousand friends on Facebook, but the number of people you are likely to interact on a daily basis will be a tiny subset of them, perhaps on the order of 0 to 20. And among the people you interact with, you are likely interacting much more word-count-wise with some than with the others. Indeed, if you plot the number of words exchanged in private messages between people in an information network, the distribution follows a long-tail.

*** In the long-run, this may also have to apply to information networks. Whether information networks will need also some level of top-down control will be a difficult question to answer that requires a complex cost-benefit analysis beyond the scope of this article. The most important variables being (a) what the benefits of fully-free communication are, and (b) the density and severity of memetic hazards in idea-space, in conjunction with the nature of intellectual selection pressures in future societies. If it turns out that people above a certain level of education and intelligence in a future with far more advanced science and engineering are extremely likely to encounter what Nick Bostrom calls “black balls”, there might be no way around developing tight controls on information networks for the safety of everyone. It this happens, we could also use many of the strategies outlined in this article for contact networks. After all, viruses are related to contact networks in the same way as meme hazards are related to information networks.

**** Of course, in some ways this is more about collective emotional processing than about object-level problem solving.

***** It is worth noting that the better air quality might buffer a bit against these negatives.

One for All and All for One

By David Pearce (response to Quora question: “What does David Pearce think of closed, empty, and open individualism?“)


Vedanta teaches that consciousness is singular, all happenings are played out in one universal consciousness and there is no multiplicity of selves.

 

– Erwin Schrödinger, ‘My View of the World’, 1951

Enlightenment came to me suddenly and unexpectedly one afternoon in March [1939] when I was walking up to the school notice board to see whether my name was on the list for tomorrow’s football game. I was not on the list. And in a blinding flash of inner light I saw the answer to both my problems, the problem of war and the problem of injustice. The answer was amazingly simple. I called it Cosmic Unity. Cosmic Unity said: There is only one of us. We are all the same person. I am you and I am Winston Churchill and Hitler and Gandhi and everybody. There is no problem of injustice because your sufferings are also mine. There will be no problem of war as soon as you understand that in killing me you are only killing yourself.

 

– Freeman Dyson, ‘Disturbing the Universe’, 1979

Common sense assumes “closed” individualism: we are born, live awhile, and then die. Common sense is wrong about most things, and the assumption of enduring metaphysical egos is true to form. Philosophers sometimes speak of the “indiscernibility of identicals”. If a = b, then everything true of a is true of b. This basic principle of logic is trivially true. Our legal system, economy, politics, academic institutions and personal relationships assume it’s false. Violation of elementary logic is a precondition of everyday social life. It’s hard to imagine any human society that wasn’t founded on such a fiction. The myth of enduring metaphysical egos and “closed” individualism also leads to a justice system based on scapegoating. If we were accurately individuated, then such scapegoating would seem absurd.

Among the world’s major belief-systems, Buddhism comes closest to acknowledging “empty” individualism: enduring egos are a myth (cf. “non-self” or Anatta – Wikipedia). But Buddhism isn’t consistent. All our woes are supposedly the product of bad “karma”, the sum of our actions in this and previous states of existence. Karma as understood by Buddhists isn’t the deterministic cause and effect of classical physics, but rather the contribution of bad intent and bad deeds to bad rebirths.

Among secular philosophers, the best-known defender of (what we would now call) empty individualism minus the metaphysical accretions is often reckoned David Hume. Yet Hume was also a “bundle theorist”, sceptical of the diachronic and the synchronic unity of the self. At any given moment, you aren’t a unified subject (“For my part, when I enter most intimately into what I call myself, I always stumble on some particular perception or other, of heat, cold, light or shade, love or hatred, pain or pleasure. I can never catch myself at any time without a perception, and can never observe anything but the perception” (‘On Personal Identity’, A Treatise of Human Nature, 1739)). So strictly, Hume wasn’t even an empty individualist. Contrast Kant’s “transcendental unity of apperception”, aka the unity of the self.

An advocate of common-sense closed individualism might object that critics are abusing language. Thus “Winston Churchill”, say, is just the name given to an extended person born in 1874 who died in 1965. But adhering to this usage would mean abandoning the concept of agency. When you raise your hand, a temporally extended entity born decades ago doesn’t raise its collective hand. Raising your hand is a specific, spatio-temporally located event. In order to make sense of agency, only a “thin” sense of personal identity can work.

According to “open” individualism, there exists only one numerically identical subject who is everyone at all times. Open individualism was christened by philosopher Daniel Kolak, author of I Am You (2004). The roots of open individualism are ancient, stretching back at least to the Upanishads. The older name is monopsychism. I am Jesus, Moses and Einstein, but also Hitler, Stalin and Genghis Khan. And I am also all pigs, dinosaurs and ants: subjects of experience date to the late Pre-Cambrian, if not earlier.

My view?
My ethical sympathies lie with open individualism; but as it stands, I don’t see how a monopsychist theory of identity can be true. Open or closed individualism might (tenuously) be defensible if we were electrons (cfOne-electron universe – Wikipedia). However, sentient beings are qualitatively and numerically different. For example, the half-life of a typical protein in the brain is an estimated 12–14 days. Identity over time is a genetically adaptive fiction for the fleetingly unified subjects of experience generated by the CNS of animals evolved under pressure of natural selection (cfWas Parfit correct we’re not the same person that we were when we were born?). Even memory is a mode of present experience. Both open and closed individualism are false.

By contrast, the fleeting synchronic unity of the self is real, scientifically unexplained (cfthe binding problem) and genetically adaptive. How a pack of supposedly decohered membrane-bound neurons achieves a classically impossible feat of virtual world-making leads us into deep philosophical waters. But whatever the explanation, I think empty individualism is true. Thus I share with my namesakes – the authors of The Hedonistic Imperative (1995) – the view that we ought to abolish the biology of suffering in favour of genetically-programmed gradients of superhuman bliss. Yet my namesakes elsewhere in tenselessly existing space-time (or Hilbert space) physically differ from the multiple David Pearces (DPs) responding to your question. Using numerical superscripts, e.g. DP^564356, DP^54346 (etc), might be less inappropriate than using a single name. But even “DP” here is misleading because such usage suggests an enduring carrier of identity. No such enduring carrier exists, merely modestly dynamically stable patterns of fundamental quantum fields. Primitive primate minds were not designed to “carve Nature at the joints”.

However, just because a theory is true doesn’t mean humans ought to believe in it. What matters are its ethical consequences. Will the world be a better or worse place if most of us are closed, empty or open individualists? Psychologically, empty individualism is probably the least emotionally satisfying account of personal identity – convenient when informing an importunate debt-collection company they are confusing you with someone else, but otherwise a recipe for fecklessness, irresponsibility and overly-demanding feats of altruism. Humans would be more civilised if most people believed in open individualism. The factory-farmed pig destined to be turned into a bacon sandwich is really youthe conventional distinction between selfishness and altruism collapses. Selfish behaviour is actually self-harming. Not just moral decency, but decision-theoretic rationality dictates choosing a veggie burger rather than a meat burger. Contrast the metaphysical closed individualism assumed by, say, the Less Wrong Decision Theory FAQ. And indeed, all first-person facts, not least the distress of a horribly abused pig, are equally real. None are ontologically privileged. More speculatively, if non-materialist physicalism is true, then fields of subjectivity are what the mathematical formalism of quantum field theory describes. The intrinsic nature argument proposes that only experience is physically real. On this story, the mathematical machinery of modern physics is transposed to an idealist ontology. This conjecture is hard to swallow; I’m agnostic.

Bern, 20. 5. 2003 Copyright Peter Mosimann: Kuppel

One for all, all for one” – unofficial motto of Switzerland.

Speculative solutions to the Hard Problem of consciousness aside, the egocentric delusion of Darwinian life is too strong for most people to embrace open individualism with conviction. Closed individualism is massively fitness-enhancing (cfAre you the center of the universe?). Moreover, temperamentally happy people tend to have a strong sense of enduring personal identity and agency; depressives have a weaker sense of personhood. Most of the worthwhile things in this world (as well as its biggest horrors) are accomplished by narcissistic closed individualists with towering egos. Consider the transhumanist agenda. Working on a cure for the terrible disorder we know as aging might in theory be undertaken by empty individualists or open individualists; but in practice, the impetus for defeating death and aging comes from strong-minded and “selfish” closed individualists who don’t want their enduring metaphysical egos to perish. Likewise, the well-being of all sentience in our forward light-cone – the primary focus of most DPs – will probably be delivered by closed individualists. Benevolent egomaniacs will most likely save the world.

One for all, all for one”, as Alexandre Dumas put it in The Three Musketeers?
Maybe one day: full-spectrum superintelligence won’t have a false theory of personal identity. “Unus pro omnibus, omnes pro uno” is the unofficial motto of Switzerland. It deserves to be the ethos of the universe.

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Qualia Productions Presents: When AI Equals Advanced Incompetence

By Maggie and Anders Amelin

Letter I: Introduction

We are Maggie & Anders. A mostly harmless Swedish old-timer couple only now beginning to discover the advanced incompetence that is the proto-science — or “alchemy” — of consciousness research. A few centuries ago a philosopher of chemistry could have claimed with a straight face to be quite certain that a substance with negative mass had to be invoked to explain the phenomenon of combustion. Another could have been equally convinced that the chemistry of life involves a special force of nature absent from all non-living matter. A physicist of today may recognize that the study of consciousness has even less experimental foundation than alchemy did, yet be confident that at least it cannot feel like something to be a black hole. Since, obviously, black holes are simple objects and consciousness is a phenomenon which only emerges from “complexity” as high as that of a human brain.

Is there some ultimate substrate, basic to reality and which has properties intrinsic to itself? If so, is elementary sentience one of those properties? Or is it “turtles all the way down” in a long regress where all of reality can be modeled as patterns within patterns within patterns ending in Turing-style “bits”? Or parsimoniously never ending?

Will it turn out to be patterns all the way down, or sentience all the way up? Should people who believe themselves to perhaps be in an ancestor simulation take for granted that consciousness exists for biologically-based people in base-level reality? David Chalmers does. So at least that must be one assumption it is safe to make, isn’t it? And the one about no sentience existing in a black hole. And the one about phlogiston. And the four chemical elements.

This really is good material for silly comedy or artistic satire. To view a modest attempt by us in that direction, please feel encouraged to enjoy this youtube video we made with QRI in mind:

When ignorance is near complete, it is vital to think outside the proverbial box if progress is to be made. However, spontaneous creative speculation is more context-constrained than it feels like, and it rarely correlates all that beautifully with anything useful. Any science has to work via the baby steps of testable predictions. The integrated information theory (IIT) does just that, and has produced encouraging early results. IIT could turn out to be a good starting point for eventually mapping and modeling all of experiential phenomenology. For a perspective, IIT 3.0 may be comparable to how Einstein’s modeling of the photoelectric effect stands in relation to a full-blown theory of quantum gravity. There is a fair bit of ground to cover. We have not been able to find any group more likely than the QRI to speed up the process whereby humanity eventually manages to cover that ground. That is, if they get a whole lot of help in the form of outreach, fundraising and technological development. Early pioneers have big hurdles to overcome, but the difference they can make for the future is enormous.anders_and_maggie_thermometer

For those who feel inspired, a nice start is to go through all that is on or linked via the QRI website. Indulge in Principia Qualia. If that leaves you confused on a higher level, you are in good company. With us. We are halfway senile and are not information theorists, neuroscientists or physicists. All we have is a nerdy sense of humor and work experience in areas like marketing and planetary geochemistry. One thing we think we can do is help bridge the gap between “experts” and “lay people”. Instead of “explain it like I am five”, we offer the even greater challenge of explaining it like we are Maggie & Anders. Manage that, and you will definitely be wiser afterwards!

– Maggie & Anders


Letter II: State-Space of Matter and State-Space of Consciousness

A core aspect of science is the mapping out of distributions, spectra, and state-spaces of the building blocks of reality. Naturally occurring states of things can be spontaneously discovered. To gain more information about them, one can experimentally alter such states to produce novel ones, and then analyze them in a systematic way.

The full state-space of matter is multidimensional and vast. Zoom in anywhere in it and there will be a number of characteristic physics phenomena appearing there. Within a model of the state-space you can follow independent directions as you move towards regions and points. As an example, you can hold steady at one particular simple chemical configuration. Diamond, say. The stable region of diamond and its emergent properties like high hardness extends certain distances in other parameter directions such as temperature and pressure. The diamond region has neighboring regions with differently structured carbon, such as graphite. Diamond and graphite make for an interesting case since the property of hardness emerges very differently in the two regions. (In the pure carbon state-space the dimensions denoting amounts of all other elements can be said to be there but set to zero). Material properties like hardness can be modeled as static phenomena. According to IIT however, consciousness cannot. It’s still an emergent property of matter though, so just stay in the matter state-space and add a time dimension to it. Then open chains and closed loops of causation emerge as a sort of fundamental level of what matter “does”. Each elementary step of causation may be regarded to produce or intrinsically be some iota of proto-experience. In feedback loops this self-amplifies into states of feeling like something. Many or perhaps most forms of matter can “do” these basic things at various regions of various combinations of parameter settings. Closed causal loops require more delicate fine-tuning in parameter space, so the state-space of nonconscious causation structure is larger than that of conscious structure. The famous “hard problem” has to do with the fact that both an experientially very weak and a very strong state can emerge from the same matter (shown to be the case so far only within brains). A bit like the huge difference in mechanical hardness of diamond and graphite both emerging from the same pure carbon substrate (a word play on “hard” to make it sticky).