7 Recent Videos: Consciousness vs. Replicators, High Entropy Alloys of Experience, Sleep Paralysis Stories, Free-Wheeling Hallucinations, Zero Ontology, The Tyranny of the Intentional Object, And A Language for Psychedelic Experiences

[See: Previous 7-video package]

A Universal Plot – Consciousness vs. Pure Replicators: Gene Servants or Blissful Autopoietic Beings? (link)

What is the point of it all? What does it all mean?

In this talk I explain how we can meaningfully address these questions with the frame of “consciousness vs. pure replicators”. This framework allows us to re-interpret and unify all previous “scales of moral/conceptual development”. In turn, it makes solving disagreements in a principled way possible.

“Consciousness vs. Pure Replicators” is what I call “the universal plot of reality”; it is the highest level of narrative that determines what is “relevant to the plot” at any given point in time.

Whether consciousness succeeds at gaining control of its destiny and embarks on a collective journey of self-authorship, or whether we all end up being subservient cogs to a self-replicating mega-system whose one and only utility function is to self-perpetuate, is truly up in the air right now. So what can we do to support the interests of consciousness, then?

To aid consciousness we need more than good intentions (though those are still a key ingredient): I discuss how game theoretical considerations entail that in order for consciousness to succeed we will need to judiciously ally with specific replicator strategies. Being a “cooperatebot” towards anyone who claims to care about consciousness makes you liable to being resource-pumped. You need to verify that something makes sense also from the point of view of game theory; without a way to verify the ultimate values of others, coordinating with them at this level becomes extremely challenging. I suggest that a mature technology of intelligent bliss with objectively verifiable effects would be a game-changer. Once you’ve seen “it” (i.e. optimized bliss consciousness) you join everyone else in self-organizing around it.

If the world is to be taken over by something that cares about the wellbeing of consciousness, how this taking over process looks like may blindside us all. The power of “universal love” conquering all obstacles and creating a paradise for all may not be a New Age fantasy after all. Given the appropriate technology, it may turn out to be a live option…

Topics Covered: Kegan Levels of Development, Spiral Dynamics, Model of Hierarchical Complexity, Meta-Modernism, Qualia Formalism, Valence Structuralism, Pleasure Principle, Open Individualism, Universal Darwinism, Battle Between Good and Evil, Balance Between Good and Evil, Gradients of Wisdom, Consciousness vs. Pure Replicators, Wild Animal Suffering, Mistrusting DMT Entities, Super-Cooperator Cluster, Metta/Lovingkindness, State-Dependent Sexuality, Wireheading, Cooperation Technology, Game-Changing as a Strategy.

~Qualia of the Day: Kala Namak~

Further Readings:


High Entropy Alloys of Experience (link)

~Suggestion: Play a music album you like in the background while listening to this talk.~

How do we find the “gems” hidden in the state-space of consciousness?

In this talk I articulate why it is very likely that there is a huge number of undiscovered states of consciousness that are completely unique, irreducible, and wholistically “special”.

In metallurgy, a high-entropy alloy (HEA) is a mixture of five or more metals in high proportions, often giving rise to a single phase. Some HEAs have been found to have extremely desirable properties from the point of view of material science (such as being the best at both yield-strength and ultimate tensile strength at the same time). Given the huge space of possible mixtures of metals, finding these carefully balanced mixtures with unique emergent properties is both a science and an art. It calls for intelligent strategies to explore the state-space of possible alloys!

I suggest that in the realm of consciousness there are also states that would be appropriate to describe as “high entropy alloys of experience”. I go into how this framework can help us understand unique scents*. We then explore how the receptor affinity profiles of drugs, drug cocktails, and drug schedules can give rise to unique HEA-like states of mind. I then also discuss how memeplexes have various degrees of total complexity, and how this makes some more receptive to dealing with complexity in the world than others. I offer that I really appreciate the HEA-like memeplexes that get expressed in places like EAGlobal, The Science of Consciousness, and Psychedelic Science conferences. I conclude by reflecting on how a “productive mindset” or mood optimized for a specific intellectual job is likely to be HEA-like because it requires the careful balance between many different facets of the mind.

Topics you will master after seeing this talk for even just one time**: High Entropy Alloys, Bronze and Iron Age, Equiatomic Alloys, People Clusters in Parties, Scents, Sexual Orientation, Gay Fragrances, Memeplexes and Mindsets, Vibe of Groups, Energy Parameter, Frozen Food, Crystallites, Space Groups, The Science of Consciousness, EAGlobal, Psychedelic Science, Search Heuristics, DMT as “Competing Clusters of Synchrony”, Birthday Cake Flavor, Cellular Automata, Optimal Mood for Productivity.

*(HEAs: Le Male by JPG, Bleu de Chanel, Mitsouko by Guerlain. Non-HEAs: Tommy Girl by Tommy Hilfiger, Habit Rouge by Guerlain, Amazing Grace Ballet Rose by Philosophy)

**More like “topics barely touched upon”.

Further Readings:

Heterosexual males and females preferred odours from heterosexual males relative to gay males; gay males preferred odours from other gay males.

Source: Sense of smell is linked to sexual orientation, study reveals

If the goal is to avoid the formation of such phases, simply mixing together five or more elements in near-equiatomic concentrations is unlikely to be a useful approach. Even multi-component alloys that are initially single phase after solidification tend to separate into multiple metallic and intermetallic phases when annealed at intermediate temperatures.

Source: High-entropy Alloys (literature review)

Featured image source: @fractjack


6 Spooky Sleep Paralysis Stories (link)

I estimate that I have experienced between 100 and 200 sleep paralysis, many of which were lucid (meaning that I knew I was experiencing a sleep paralysis). In this video I articulate what I have learned from all of these experiences, share some particularly strange stories, and give you tips for how to get out of a sleep paralysis if you find yourself trapped in one.

Topics Covered: Hyperbolic curvature in pasta, dream music, phenomenal viscosity, DXM, imperfect sensory gating, “radio is playing” hallucinations, Dredg – Album: El Cielo · Song: Scissor Lock, taking psychedelics while dreaming, lucid dreams, dopaminergics, controlling the powerful vibrations of sleep paralysis, recursive depth, false awakenings, whimpering, noting meditation, and techniques for escaping a sleep paralysis.

~Qualia of the Day: Gigli/Campanelle Pasta~

Further Readings:

Niacinamide helps in sleep enhancement as evidenced in a 3-week study of six subjects with normal sleep patterns and two with insomnia using electroencephalograms, electromyograms, and electrooculograms to evaluate sleep patterns at baseline and after niacinamide treatment. There was a significant increase in REM sleep in all normal-sleeping subjects, but the two subjects with moderate to severe insomnia experienced significant increases in REM sleep by the third week; awake time was also significantly decreased (Robinson et al., 1977).

(source)

Free-Wheeling Hallucinations: Be the Free-Willed God of Your Inner World-Simulation (link)

Once you realize that you inhabit a world-simulation sustained by your neuronal soil it is natural to ask: why can’t I control its contents? Why can’t I make myself hallucinate whatever I want?

It can be frustrating to realize one lacks control over something that should be truly “ours” – our raw unmediated experience! We could, and perhaps should, be the rightful masters of our very own conscious experience, yet for the most part we remain powerless to explore its possible states at will.

In this video I discuss the existence of some states of consciousness in which you do own and control the contents of your experience. Think of it as acquiring an “experience editor”: an interface with your experience that enables you to modify it at will while keeping the modifications stable.

A lucid dream would be an example of a somewhat fluid and unreliable free-wheeling hallucination. The free-wheeling hallucinations I describe here are much more general, stable, reliable, intense, and hedonic than lucid dreams. More so, to spin up free-wheeling hallucinations could amount to far more than being just a fun activity. Doing so may come to be an extremely valuable tool for a new paradigm of consciousness research! All of the parameters of experience that remain outside of our control under normal circumstances can be studied (both from a first and third person point of view) while in a free-wheeling hallucination! One can conduct a sort of “qualia chemistry” and repeat experiments to get reliable accounts of the behavior of consciousness under exotic (yet controlled) circumstances. Artifacts such as the valence-symmetry correspondance can be inspected in detail. Ultimately, this paradigm may allow us to chart the state-space of consciousness in terms of “edit distances” or “sequence of symmetry breaking operations” away from “formless consciousness”.

I then go on to explain that “knowing everything about your world-simulation” does not entail that the experience will be boring. Hedonic tone can be dissociated from novelty, but we don’t even need to go that far. It suffices to point out that you can set up the parameters of your world-simulation so that it unfolds in a chaotic way, and thus is impossible to predict. Additionally, you cannot really predict what you yourself will think in the future, so the whole setup can continue to generate novelty almost indefinitely (up to one’s storage capacity/size of the state-space/heat death of the universe).

I conclude by exercising my free will.

Topics Covered: Energy Parameter, Predictive Coding, Free Energy Principle, Kolmogorov Complexity of Experience, Principia Qualia, Super Free Will, Quality Trip Reports, DXM + THC Combo, LSD + Ketamine + THC Combo, “Experience Editors”, Qualia Critters, Fire Kasina, Color Control, Qualia Chemistry, Agenthood, Coumarin, Chamomile Tea.

~Qualia of the Day: You Have to Watch the Video~

Further Readings:

Chamomile consists of several ingredients including coumarin, glycoside, herniarin, flavonoid, farnesol, nerolidol and germacranolide. Despite the presence of coumarin, as chamomile’s effect on the coagulation system has not yet been studied, it is unknown if a clinically significant drug-herb interaction exists with antiplatelet/anticoagulant drugs. However, until more information is available, it is not recommended to use these substances concurrently.

Source: Herbal medication: potential for adverse interactions with analgesic drugs

Why Does Anything Exist? Zero Ontology, Physical Information, and Pure Awareness (link)

Why is there something rather than nothing? In this video I take this question very seriously and approach it with optimism. I say (a) this is a meaningful and valid question, and (b) it has a real and satisfying answer. The overall explanation space I explore is that of David Pearce’s Zero Ontology, which postulates that the multiverse is implied by the preservation of “zero information”.

In order to understand Zero Ontology we need to do some conceptual groundwork. So I walk the listener (you, were you to accept this journey) through several concepts that make the question go from “impossible to answer” or even “meaningless” to something that at least conceivably seems possible to solve.

First, we need to sidesteps the common tropes of our habitual modes of thinking, such as expecting answers to come in the form of “causal explanations”. No matter how you look at it, whether the universe extends back forever or not, a causal explanation for the origin of the universe is logically impossible to derive. Instead, we have to think in a radically different way, which is by way of frameworks for implication rather than causation. This opens us up to the possibility that exotic modes of thinking capable of representing what is entailed by “nothing” will show in turn that “something” follows from it. This helps us make sense of Pearce’s argument: the “nothing” we are looking for is not the “common sense” view of the term, but rather a more refined post-theoretical concept that is ill-fitted to the human mind for the time being.

In particular, Pearce focuses on how “no information” may be “what nothing is”. Thus, Zero Ontology attempts to formalize the “fact of inexistence” by reconceptualizing information as “ruling out possibilities”. Based on this alternate concept we see that math, physics, and phenomenology share the common thread of being possible to “construct out of nothing”. In math, the empty set can be used to derive all of arithmetic. In physics the Standard Model is a surprisingly simple theory that can be derived from first principles by imposing the “need for symmetry”. The total energy, charge, momentum, etc. of the universe is zero! And in phenomenology, we encounter a lot of cases where apparently all of the possible flavors of a qualia variety seem to “cancel out” into “pure being” or “raw awareness”. The simplest example is how experiencing “all phenomenal colors at once” (a kind of rainbow effect, but including magenta) seems to be interchangeable with “colorless phenomenal light”.

I tie all of this together and talk about how Zero Ontology allows us to reconceptualize “God/Being” as “unconstrained reality” or “boundarylessness”. I discuss how we could perhaps even probe Zero Ontology empirically in a direct way if we were to train enough physicists, mathematicians, philosophers, computer scientists, etc. to go into high Jhana or 5-MeO-DMT states and then quantify the properties of the fundamental fields implementing these experiences.

I conclude with an analogy to Borges’ Library of Babel (or a quantum version thereof) and why we may be in it. In fact, “be it”.

David Pearce: “A theory that explains everything explains nothing”, protests the critic of Everettian QM. To which we may reply, rather tentatively: yes, precisely.

Topics Covered: The Concept of Nothing, Three Characteristics, Illusion, Limitations of the Medium of Thought, Amusing Ourselves to Death, Redefining Information, Empty Set Arithmetic, Preserved Quantities of Physics, Symmetry and Noether’s Theorem, QFT, Path Integrals, Jhanas, 5-MeO-DMT, Symmetries in Qualia, Quantum Library of Babel, Black Hole Information Paradox.

~Qualia of the Day: Thinking About Nothing~

Further Readings:


The Tyranny of the Intentional Object: Universal Addictions, Meaning Abuse, and Denied Self-Insights (link)

What is it that we truly want? Why do so many people believe that meaning is better than happiness?

In this talk I discuss what we call “the tyranny of the intentional object”, which refers to the tendency for the mind to believe that “what it wants” is semantically meaningful experiences. In reality, what we want under the surface is to avoid negative valence and achieve sustainable positive valence states of consciousness.

I explain that evolution has “hooked us” on particular sources of pleasure in such a way that this is not introspectively accessible to us. We often need specific semantic content to work as a “key” for the “lock” of high-valence states of consciousness. I explain how we are all born chronic (endogenous) opioid addicts, and how our reward architecture is so coercive that we often fail to recognize this because thinking about it makes us feel bad (and thus ironically confirming the situation we are trying to be in denial about!).

I go on to provide my current thoughts on the nature of meaning. Beyond “sense and reference” we find that “felt-sense” is actually what meaning is “made of”. But not any kind of felt-sense. I posit that the felt-senses that we describe as richly meaningful tend to have the following properties: high levels of intention, coherence of attention field lines, a “field syntax”, and a high level of “potential to affect valence”. Valence and meaning are deeply connected but are not identical: we can find corner cases of high-valence but meaningless states of mind and vice versa (though they rare).

Meaning is no less liable to be “abused” than hard drugs: we often find ourselves scratching the bottom of the barrel of our meaning-making structures when things go wrong. I advise against doing this, and instead endorse the use of equanimity when faced with the absurd and Chapman’s “Meaningness” approach: to think of meaning as a gradient rather than in black and white terms. Do take advantage of opportunities for high levels of meaning, but do not rely on them and think they are universal. Indeed “meaning abuse” is a recipe for broken hearts and misguided idealistic solutions to problems that can be easily addressed pragmatically.

Finally, I steelman the importance of “high-dimensional valence” and explain why in turn usually pursuing meaning is indeed much better than shallow pleasure.

~Qualia of the Day: Clean Air~

Further Readings:

[T]he heroin addict will do anything to get another fix: lie, cheat, steal and worse. Natural selection has stumbled on and harnessed Nature’s own version of heroin. Our endogenous opioid system ensures that biological life behaves in callous but genetically adaptive ways. […] All complex animal life is “paid” in junk: the addictive dribble of opioids in our hedonic hotspots released when we act in ways that tend to maximise the inclusive fitness of our genes in the environment of evolutionary adaptedness (EEA). The pleasure-pain axis is coercive. Barring self-deliverance, we can’t opt out. Our “reward” circuitry hardwires opioid addiction and the complex rationalisations it spawns. Human history confirms we’ll do anything to obtain more opioids to feed our habit. The mesolimbic dopamine system enables us to anticipate our next fix and act accordingly: an insidious interplay of “wanting” and “liking”. We enslave and kill billions of sentient beings from other species to gratify our cravings. We feed the corpses of our victims to our offspring. So the vicious cycle of abuse continues.

David Pearce: Quora Responses

A Language for Psychedelic Experiences: Algorithmic Reductions, Field Operators, and Dimensionality (link)

Psychedelic experiences are notoriously difficult to describe. But are they truly ineffable, or do we simply lack the words, syntax, and grammar to articulate them? Optimistically, groups who take seriously the exploration of exotic states of consciousness could create a common ground of semantic primitives to be independently verified and used as the building blocks of a language for the “psychedelic medium of thought”.

In this video I present some ideas for a possible “psychedelic language” based on QRI paradigms and recent experience reports. I go over the article “Algorithmic Reduction of Psychedelic States” and the value of breaking the psychedelic experience in terms of a minimal set of “basic effects” whose stacking and composition gives rise to the wild zoo of effects one observes. I point out that algorithmic reductions can have explanatory power even if they do not provide a clear answer about the nature of the substrate of experience. Importantly, since I wrote that article we have developed a far higher-resolution understanding of exotic states of consciousness:

We suggest that a remarkably fruitful strategy for pointing at a whole family of psychedelic effects comes in the form of “field operators” that change the qualitative properties of our experiential fields. I provide a detailed description of what we call the “world-sheet” of experience and how it encodes emotional and semantic content in its very structure. The world-sheet can have tension, relaxation, different types of resonance and buzzing entrainment, twisting, curling, divergence (with vortices and anti-vortices in the attention field-lines), dissonance, consonance, noise, release, curvature, holographic properties, and dimensionality. I explain that in a psychedelic state, you explore higher up regions in the “Hamiltonian of the field”, meaning that you instantiate field configurations with higher levels of energy. There, we observer interesting trade-offs between the hyperbolicity of the field and its dimensionality. It can instantiate fractals of many sorts (in polar, cartesian, and other coordinate systems) by multi-scale entrainment. Time loops and moments of eternity result from this process iterated over all sensory modalities. The field contains meta-data implicitly encoded in its periphery which you can use for tacit information processing. Semantic content and preferences are encoded in terms of the patterns of attraction and repulsion of the attention-field lines. And so much more (watch the whole video for the entire story).

I conclude by saying that a steady meditation practice can be highly synergistic with psychedelics. Metta/loving-kindness can manifest in the form of smooth, coherent, high-dimensional, and consonant regions of the world-sheet and make the experience way more manageable, wholesome, and enriching. Equanimity, concentration, and sensory clarity are all synergistic with the state, and I posit that using “high-dimensionality” as the annealing target may accelerate the development of these traits in everyday life.

Please consider donating to QRI if you want to see this line of research make waves in academia and expand the Overtone Window for the science of consciousness. Funds will allow us to carry out key scientific experiments to validate models and develop technologies to reduce suffering at scale: https://www.qualiaresearchinstitute.org/donate

~Qualia of the Day: The Phenomenal Silence of Each Field Modality~

Further Readings:


That’s it for now!

Until next time!

Infinite bliss!

– Andrés

7 Recent Videos: Rational Analysis of 5-MeO-DMT, Utility Monsters, Neroli, Phenomenal Time, Benzo Withdrawal, Scale-Specific Network Geometry, and Why DMT Feels So Real

5-MeO-DMT: A Rational Analysis at Last (link)

Topics covered: Non-Duality, Symmetry, Valence, Neural Annealing, and Topological Segmentation.

See also:


Befriending Utility Monsters: Being the Adult in the Room When Talking About the Hedonic Extremes (link)

In this episode I connect a broad variety of topics with the following common thread: “What does it mean to be the adult in the room when dealing with extremely valenced states of consciousness?” Essentially, a talk on Utility Monsters.

Concretely, what does it mean to be responsible and sensible when confronted with the fact that pain and pleasure follow a long tail distribution? When discussing ultra-painful or ultra-blissful experiences one needs to take off the glasses we use to reason about “room temperature consciousness” and put on glasses that actually take these states with the seriousness they deserve.

Topics discussed include: The partial 5HT3 antagonism of ginger juice, kidney stones from vitamin C supplementation, 2C-E nausea, phenibut withdrawal, akathisia as a remarkably common side effect of psychiatric medication (neuroleptics, benzos, and SSRIs), negative 5-MeO-DMT trips, the book “LSD and the Mind of the Universe”, turbulence and laminar flow in the “energy body”, being a “mom” at a festival, and more.

Further readings on these topics:


Mapping State-Spaces of Consciousness: The Neroli Neighborhood (link)

What would it be like to have a scent-based medium of thought, with grammar, generative syntax, clauses, subordinate clauses, field geometry, and intentionality? How do we go about exploring the full state-space of scents (or any other qualia variety)?

Topics Covered in this Video: The State-space of Consciousness, Mapping State-Spaces, David Pearce at Oxford, Qualia Enrichment Kits, Character Impact vs. Flavors, Linalool Variants, Clusters of Neroli Scents, Neroli in Perfumes, Neroli vs. Orange Blossom vs. Petigrain vs. Orange/Mandarin/Lemon/Lime, High-Entropy Alloys of Scent, Musks as Reverb and Brown Noise, “Neroli Reconstructions” (synthetic), Semi-synthetic Mixtures, Winner-Takes-All Dynamics in Qualia Spaces, Multi-Phasic Scents, and Non-Euclidean State-Spaces.

Neroli Reconstruction Example:

4 – Linalool
3 – Linalyl Acetate
3 – Valencene
3 – Beta Pinene
2 – Nerolione
2 – Nerolidol
2 – Geraniol Coeur
2 – Hedione
2 – Farnesene
1 – D-Limonene
1 – Nerol
1 – Ambercore
1 – Linalool Oxyde
70 – Ethanol

Further readings:


What is Time? Explaining Time-Loops, Moments of Eternity, Time Branching, Time Reversal, and More… (link)

What is (phenomenal) time?

The feeling of time passing is not the same as physical time.

Albert Einstein discovered that “Newtonian time” was a special case of physical time, since gravity, relativity, and the constancy of the speed of light entails that space, time, mass, and gravity are intimately connected. He, in a sense, discovered a generalization of our common-sense notion of physical time; a generalization which accounts for the effects of moving and accelerating frames of reference on the relative passage of time between observers. Physical time, it turns out, could manifest in many more (exotic) ways than was previously thought.

Likewise, we find that our everyday phenomenal time (i.e. the feeling of time passing) is a special case of a far more general set of possible time-like qualities of experience. In particular, in this video I discuss “exotic phenomenal time” experiences, which include oddities such as time-loops, moments of eternity, time branching, and time reversal. I then go on to explain these exotic phenomenal time experiences with a model we call the “pseudo-time arrow”, which involves implicit causality in the network of sensations we experience on each “moment of experience”. Thus we realize that phenomenal time is an incredibly general property! It turns out that we haven’t even scratched the surface of what’s possible here… it’s about time we do so.

Further readings on this topic:


Benzos: Why the Withdrawal is Worse than the High is Good (+ Flumazenil/NAD+ Anti-Tolerance Action) (link)

Most people have low-resolution models of how drug tolerance works. Folk theories that “what goes up must come down” and theories in the medical establishment about how you can “stabilize a patient on a dose” and expect optimal effects long term get in the way of actually looking at how tolerance works.

In this video I explain why benzo withdrawal is far worse than the high they give you is good.

Core arguments presented:

  1. Benzos can treat anxiety, insomnia, palpitations, seizures, hallucinations, etc. If you use them to treat one of these symptoms, the rebound will nonetheless involve all of them.
  2. Kindling – How long-term use leads to neural annealing of the “withdrawal neural patterns”.
  3. Amnesia effects prevent you from remembering the good parts/only remembering the bad parts.
  4. Neurotoxicity from long-term benzo use makes it harder for your brain to heal.
  5. Arousal as a multiplier of consciousness: on benzos the “high” is low arousal and the withdrawal is high arousal (compared to stimulants where you at least will “sleep through the withdrawal”).
  6. Tolerance still builds up even when you don’t have a “psychoactive dose” in your body – meaning that the extremely long half-life of clonazepam and diazepam and their metabolites (50h+) entails that you still develop long-term tolerance even with weekly or biweekly use!

I then go into how the (empirically false) common-sense view of drug tolerance is delaying promising research avenues, such as “anti-tolerance drugs” (see links below). In particular, NAD+ IV and Flumazenil seem to have large effect sizes for treating benzo withdrawals. I AM NOT CONFIDENT THAT THEY WORK, but I think it is silly to not look into them with our best science at this point. Clinical trials for NAD+ IV therapy for drug withdrawal are underway, and the research to date on flumazenil seems extremely promising. Please let me know if you have any experience using either of these two tools and whether you had success with them or not.

Note: These treatments may also generalize to other GABAergic drugs like gabapentin, alcohol, and phenibut (which also have horrible withdrawals, but are far shorter than benzo withdrawal).

Further readings:

Epileptic patients who have become tolerant to the anti-seizure effects of the benzodiazepine clonazepam became seizure-free for several days after treatment with 1.5 mg of flumazenil.[14] Similarly, patients who were dependent on high doses of benzodiazepines […] were able to be stabilised on a low dose of clonazepam after 7–8 days of treatment with flumazenil.[15]”

Flumazenil has been tested against placebo in benzo-dependent subjects. Results showed that typical benzodiazepine withdrawal effects were reversed with few to no symptoms.[16] Flumazenil was also shown to produce significantly fewer withdrawal symptoms than saline in a randomized, placebo-controlled study with benzodiazepine-dependent subjects. Additionally, relapse rates were much lower during subsequent follow-up.[17]

Source: Flumazenil: Treatment for benzodiazepine dependence & tolerance

Scale-Specific Network Geometry (link)

Is it possible for the “natural growth” of a pandemic to be slower than exponential no matter where it starts? What are ways in which we can leverage the graphical properties of the “contact network” of humanity in order to control contagious diseases? In this video I offer a novel way of analyzing and designing networks that may allow us to easily prevent the exponential growth of future pandemics.

Topics covered: The difference between the aesthetic of pure math vs. applied statistics when it comes to making sense of graphs. Applications of graph analysis. Identifying people with a high centrality in social networks. Klout scores. Graphlets. Kinds of graphs: geometric, small world, scale-free, empirical (galactic core + “whiskers”). Pandemics being difficult to control due to exponential growth. Using a sort of “pandemic Klout score” to prioritize who to quarantine, who to vaccinate first. The network properties that made the plague spread so slowly in the Middle Ages. Toroidal planets as having linear pandemic growth after a certain threshold number of infections. Non-integer graph dimensionality. Dimensional chokes. And… kitchen sponges.

Readings either referenced in the video or useful to learn more about this topic:

Leskovec’s paper (the last link above):

Main Empirical Findings: Our results suggest a rather detailed and somewhat counterintuitive picture of the community structure in large networks. Several qualitative properties of community structure are nearly universal:

• Up to a size scale, which empirically is roughly 100 nodes, there not only exist well-separated communities, but also the slope of the network community profile plot is generally sloping downward. (See Fig. 1(a).) This latter point suggests, and empirically we often observe, that smaller communities can be combined into meaningful larger communities.

• At size scale of 100 nodes, we often observe the global minimum of the network community profile plot. (Although these are the “best” communities in the entire graph, they are usually connected to the remainder of the network by just a single edge.)

• Above the size scale of roughly 100 nodes, the network community profile plot gradually increases, and thus there is a nearly inverse relationship between community size and community quality. This upward slope suggests, and empirically we often observe, that as a function of increasing size, the best possible communities as they grow become more and more “blended into” the remainder of the network.

We have also examined in detail the structure of our social and information networks. We have observed that an ‘jellyfish’ or ‘octopus’ model [33, 7] provides a rough first approximation to structure of many of the networks we have examined.

Ps. Forgot to explain the sponge’s relevance: the scale-specific network geometry of a sponge is roughly hyperbolic at a small scale. Then the material is cubic at medium scale. And at the scale where you look at it as flat (being a sheet with finite thickness) it is two dimensional.


Why Does DMT Feel So Real? Multi-modal Coherence, High Temperature Parameter, Tactile Hallucinations (link)

Why does DMT feel so “real”? Why does it feel like you experience genuine mind-independent realities on DMT?

In this video I explain that we all implicitly rely on a model of which signals are trustworthy and which ones are not. In particular, in order to avoid losing one’s mind during an intense exotic experience (such as those catalyzed by psychedelics, dissociatives, or meditation) one needs to (a) know that you are altered, (b) have a good model of what that alteration entails, and (c) that the alteration is not strong enough that it breaks down either (a) or (b). So drugs that make you forget you are under the influence, or that you don’t know how to model (or have a mistaken model of) can deeply disrupt your “web of trusted beliefs”.

I argue that one cannot really import the models that one learned from other psychedelics about “what psychedelics do” to DMT; DMT alters you in a far broader way. For example, most people on LSD may mistrust what they see, but they will not mistrust what they touch (touch stays a “trusted signal” on LSD). But on DMT you can experience tactile hallucinations that are coherent with one’s visions! “Crossing the veil” on DMT is not a visual experience: it’s a multi-modal experience, like entering a cave hiding behind a waterfall.

Some of the signals that DMT messes with that often convince people that what they experienced was mind-independent include:

  1. Hyperbolic geometry and mathematical complexity; experiencing “impossible objects”.
  2. Incredibly high-resolution multi-modal integration: hallucinations are “coherent” across senses.
  3. Philosophical qualia enhancement: it alters not only your senses and emotions, but also “the way you organize models of reality”.
  4. More “energized” experiences feel inherently more real, and DMT can increase the energy parameter to an extreme degree.
  5. Highly valenced experiences also feel more real – the bliss and the horror are interpreted as “belonging to the vibe of a reality” rather than being just a property of your experience.
  6. DMT can give you powerful hallucinations in every modality: not only visual hallucinations, but also tactile, auditory, scent, taste, and proprioception.
  7. Novel and exotic feelings of “electromagnetism”.
  8. Sense of “wisdom”.
  9. Knowledge of your feelings: the entities know more about you than you yourself know about yourself.

With all of these signals being liable to chaotic alterations on DMT it makes sense that even very bright and rational people may experience a “shift” in their beliefs about reality. The trusted signals will have altered their consilience point. And since each point of consilience between trusted signals entails a worldview, people who believe in the independent reality of the realms disclosed by DMT share trust in some signals most people don’t even know exist. We can expect some pushback for this analysis by people who trust any of the signals altered by DMT listed above. Which is fine! But… if we want to create a rational Super-Shulgin Academy to really make some serious progress in mapping-out the state-space of consciousness, we will need to prevent epistemological mishaps. I.e. We have to model insanity so that we ourselves can stay sane.

[Skip to 4:20 if you don’t care about the scent of rose – the Qualia of the Day today]

Further readings:

“The most common descriptive labels for the entity were being, guide, spirit, alien, and helper. […] Most respondents endorsed that the entity had the attributes of being conscious, intelligent, and benevolent, existed in some real but different dimension of reality, and continued to exist after the encounter.”

Source: Survey of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine: Phenomenology, interpretation, and enduring effects

That’s it for now!

Please feel free to suggest topics for future videos!

Infinite bliss!

– Andrés

The Symmetry Theory of Valence: 2020 Presentation

Presentation Given at the Centre for Psychedelic Research at Imperial College London by Andrés Gómez Emilsson (December 8th 2020)

 www.qualiaresearchinstitute.org

Transcribed with otter.ai. Edited for grammar and clarity by Mackenzie Dion.

Watch the talk on our Youtube channel.


So, the Symmetry Theory of Valence. Just defining terms so that we’re all on the same page. There’s this thing called core affect which is basically what you get when you apply dimensionality reduction techniques to any one of many areas of psychology. There’s a surprisingly robust pair of dimensions that emerge in co-occurrences of words or even descriptions of behavior. These two axes, arousal and valence, seem to account for about 60% of the variance in terms of what information emotional words contain. And I mean, roughly speaking, arousal is the level of activation, how energetic you are, and valence is how good you feel. Most of what I’m going to be talking about is valence. That said, you need to also consider arousal in the picture to know what this is all about. Just a few examples: you have high arousal, high valence, so that would be kind of excitement and anticipation. But you also can have high energy, but not feeling really good, and that would be kind of anxiety or anger or irritation. Likewise, you have depression, which is low arousal, low valence, and serenity is peaceful, blissful calm, that would be low arousal, high valence. 

This is just one example of one of the ways in which you can recover these dimensions of valence and arousal. This was a little study we conducted years ago. We were studying people who have experiences with all kinds of substances online. We were giving them the survey, where they were going to describe a particular substance along something like 70 different dimensions. Then I conducted factor analysis on that data set. Interestingly, we have three core dimensions of valence or valence-related axes, which give you a sense of, okay, what is the space of possible effects that you can get from some substances. There were actually six dimensions that emerged, but three of them are valence-related:

We have slow euphoria, which is equivalent to low arousal, high valence with top terms like calming and relieving. The negative predictors of it would be something like anxiety, producing difficult bodily discomfort. Fast euphoria is the sort of thing you get with stimulants, you know, energizing, sociable, the opposite of feeling spaced out and confused.

The other axis that kind of emerged was this notion of spiritual euphoria. That’s the term I used back then. I also used the term significance, or saliency nowadays. Now I would actually use the term criticality for other reasons that we can go into. There’s this other kind of axis for how you can experience intense valence with substances, which is different from slow and fast euphoria, which would roughly correspond to the psychedelic space. And that, you know, gets marked with things such as mystical, incredible, life changing. The opposite of that is trivial, self-centered, or irrelevant or something like that. This is just to complete the cube. And, you know, in a sense…

This is just a kind of change of basis, where you still get, in a sense, the valence dimension emerging out of this dimensionality reduction analysis. If you were to apply just one dimension, you know, if you ask the factor analysis to just give you one factor, it is going to be the valence factor. That’s the axis that accounts for most of the variance for the effects of drugs.

I’ve got to say that I absolutely acknowledge that emotions are far more complex and intricate than just valence and arousal. This is the result of my master’s thesis where we were analyzing this thing called mood updates, how people feel over time, day after day. I was computing the transition probabilities between emotions, and you can do cluster analysis here and finding attractors. You’ll see that there’s additional information. That said, we concluded that a big chunk of the additional information that is not valence and arousal is actually information about your trajectory in the valence arousal space. For example, we found there would be emotions that because of what they tell you about your emotional dynamics we called gateway emotions, like feeling relieved and feeling hopeful. These terms contain information that you were in a negative, kind of depressive attractor, and you’re moving towards the positive high arousal attractor. In essence, the terms we use for emotions give you not only information about where you are in the valence-arousal space but also what is your trajectory in that space. But in a sense, valence and arousal still account for a very, very big chunk of what an emotion is. Okay, so hopefully I’ve convinced you of the importance of valence, at least in this context.

Now, let’s jump into the Symmetry Theory of Valence (STV). The overall hypotheses and the first explicit argument for it appeared in this really, really awesome work by my collaborator, Michael Johnson, Principia Qualia. He has a really interesting skeleton of an argument that points to a lot of research threads that are really worth getting into. I highly recommend digging into this work.

One of the things that it lays out is the kind of conceptual framework to make sense of what type of thing valence might be. I’ll just define a couple terms, which is, first qualia formalism. If there’s one thing at QRI we are married to, you could say, it would be qualia formalism. That is, for any conscious experience, there exists a mathematical object isomorphic to it. We can make an analogy here to something like electromagnetism where we used to have lightning, and electricity, and magnets, and all of that seemed sort of somehow thinly related. But, it turns out that there’s actually just four equations of electromagnetism that tie together all of that phenomena. And you can compare it to something like élan vital, the essence of life. People used to think that maybe there is some kind of a substance that determines whether you’re alive or not. And we would say that, well, that kind of fell through, you know, in the end there is molecular complexity under more molecular complexity. There doesn’t seem to be such a thing as “life itself”. Life is not formalizable in the same way as electromagnetism is, but something that we would claim at QRI or we could even say something that we assume at QRI, because we believe it is a very generative frame, is that yes, there will be a set of deep mathematical structures to consciousness. In particular, if you expand this into other areas, we also think this is going to apply to valence: that there is going to be a deep and rich mathematical structure to valence, and that notion is called valence structuralism.

In Principia Qualia by Mike Johnson, he has this argument for it, which I definitely recommend reading, especially if you have the aesthetic of a physicist. I think you’ll really like this work, because I think it’s really, really good in that sense. What I’m going to do now is try to give you a kind of intuition for it. And then the whole empirical argument.

Importantly, there are a lot of theories of what valence is. Mike looked at the literature, did a very deep dive into it, and realized that they’re usually unsatisfactory, or at the very least, they don’t get at the true core of what an explanation for valence should be like. So basically, you have these accounts of, for example, valence sees how the brain represents value. Ultimately, that’s just a correlation. Value is a fuzzy abstraction. Some people think valence is the presence of opioids in the brain. But if you inject opioids in different parts of the brain, it doesn’t always feel good. It actually needs to be injected in a very narrow range of stripes in the pleasure centers, and otherwise, it just causes strange feelings or wanting, but it’s not the signature of valence itself. Or, for example, the pleasure centers. Just because you’re calling something “the pleasure center”, and it’s correlated with feeling good, it doesn’t mean you have an explanation. It’s not a very insightful, illuminating, account of valence. 

So what could it be? I’ll focus to a large extent on what we are going to call bliss, which is just very positive valence. What is that? What is very positive valence? What is the sense of ecstasy, bliss, intense happiness? There’s a lot of intuitions. Definitely a lot of people think it’s some kind of spiritual signal, and I wouldn’t want to convince you out of that view. But the truth is that there are a lot of different spiritualities, and they sometimes say contradictory things. So it’s kind of strange to expect that there’s this underlying universal spiritual signal that whenever you’re doing something aligned with spirit, you feel good. Because sometimes you can do something very different than somebody else and still have that feeling. Also, the idea that it is “merely” chemical reactions in the brain, again, is not a super satisfactory explanation… same as with pleasure centers, health, few prediction errors, etc. Well, and in the end, I add, yes, symmetry and consciousness, which is what I will be arguing.

I also want to point out, and this is super important, that valence is not the same as healing, and it’s not the same as meaning. However, they’re correlated. I would also go as far as to say that high valence is necessary for healing and for meaning to a large extent. In a sense, you can have a lot of very high valence states that are actually very unhealthy for you. Just an example would be methamphetamine. It can feel great, but it’s unsustainable. To the extent that your nervous system is self-organizing around that high valence experience, it makes it kind of the center of your life. And, you know, it’s a dopamine releaser. It’s obviously unsustainable. You can’t actually do that long-term and expect good results. Whereas, something like meditation, or even psychedelics, because their tolerance mechanism is very, very different. You could say that, yeah, those might be high valence, highly meaningful, and also healing experiences.

So I just want to say that, you know, high valence doesn’t entail healing. And that in that sense, you might say, “Okay, why are we so interested in this?”, but I would say that high valence is a necessary condition for deep healing. And I would even go as far as to say that, for a psychedelic experience to be deeply healing, it has to involve high valence in one context or another. Of course, you may end up processing a lot of very difficult emotions. But ideally, it would be something that basically allows you to heal those difficult emotions and transform them into a state of mind that has many more of the positive qualities. 

And more so, high valence, even according to the Buddha, is an important factor for awakening. Of the seven factors for awakening, I would actually say about five of them are very connected to valence. Mindfulness, joy, relaxation, concentration, equanimity; they are kind of different flavors of high valence. They’re different ways in which a very high valence experience can manifest. The Buddha says that these are important things. Even if you only care about awakening, enlightenment, you may also care about the mathematics of valence. It might point you in the right direction as well.

I’ll also mention, there’s a big difference between the recipe of a state of consciousness and what you might call the review, or the description, of that state of consciousness. I’ll make an analogy with cooking: if you have cooking instructions for how to make a cake, sometimes it’s very counterintuitive what the cake is going to taste based on those instructions. Like “add yeast” for example. A lot of things in the recipe you may not know exactly how are going to actually affect the result. So, the recipe may look very different from the review of the state. I would say that for a lot of meditation states, or even just general life advice, this idea of don’t mindlessly chasing pleasure or trying to satisfy all of your existing desires compulsively gives counter-intuitive results. Yeah, chasing pleasure compulsively is not going to result in a sustainable high valence. To some extent, a lot of meditation instructions tell you to neither approach nor withdraw from emotions to develop equanimity. Since you are not engaging with your emotions, it sounds like the result is a fully neutral experience, right? It sounds like it’s unrelated to valence, almost cutting out the valence. But I would say: that’s just the recipe. Those are the instructions for how you manage your attention in order to eventually change your brain to actually generate these very healthy, sustainable, high valence states. So I definitely want to overcome this prejudice of thinking that high valence is unrelated to spirituality. No, I think they’re actually very deeply, intimately connected. 

Okay, so let’s go into the Symmetry Theory of Valence. I’ll just read these, but we will go into more depth into all of these. So, you know, we talked about qualia formalism, there is a mathematical object whose features are isomorphic to phenomenology. We believe that, yeah, harmony basically feels good because it’s symmetry over time. And basically, there’s kind of this duality between symmetry and space and synchrony in time. We will go over pleasure centers. The way we explain pleasure centers in this theory is that they are kind of tuning knobs (this was first proposed in Principia Qualia). They are there these bridges that, basically, when they get activated, they enable global large-scale synchrony in the brain. This is something that ultimately is very testable. Because if you can activate the pleasure centers, or inhibit whole brain harmony, we predict that’s going to actually negate the positive valence effects of the pleasure centers. Likewise, if we can induce large scale harmony, without activating the pleasure centers, or maybe even inhibiting the pleasure centers, we expect that to be a high valence state. So, it’s a cool, testable interpretation of what pleasure centers even are. 

Boredom is kind of an anti symmetry mechanism. So that’s why even if you look at a cathedral or something like that, you’re not going to be happy forever. You’re going to be happy for a little bit. Because your brain realizes that you’re not learning anything, and adds kind of this dissonance in order to make you move on to something else. We are wired in such a way that what helps us reproduce symmetrifies our consciousness. So, it’s not that high calorie food in and of itself is symmetrical, it’s not that it in and of itself is pleasant. It’s more that the way our nervous system is programmed is such that when you eat high calorie food, it triggers high valence. And that triggered high valence is what would be symmetrical, not necessarily the chemicals that you’re eating.

Importantly, valence, we think, has these three dimensions, which is positive, neutral, and negative. And you can actually have highly mixed experiences. You can have experiences, I don’t know, an example is you’re at a concert, enjoying yourself, but also you have to go to the bathroom, and you just broke up with your boyfriend. You can have these very complex mixed valence experiences, where parts of your experience are very pleasant, parts are very distressing, parts of those are very neutral, and that’s fine. At the same time, it still kind of collapses into this ultimately, “Hey, are you having a good time or not?”.

And something that the Symmetry Theory of Valence would say, and this is a pretty interesting kind of relationship, and I’ll explain it in a couple slides. This is just to kind of put it out there in your head to bounce around as we go on, which is that we expect there to be a very, very intimate relationship between information content, and basically the range of valence that you have access to. So in brief, for very, very high valence states of consciousness, we expect those to have very close to zero information. Whereas, when you have this state that is close to pure white noise, we expect that to be basically zero valence. Hopefully, this will make more sense as we go along.

These are just some illustrations of this principle. Actually, we expect that some of the most negative experiences out there will actually be pretty close to very, very highly symmetrical. I put this disjointed lattice at the bottom. And I would claim that something like a bad 5-MeO-DMT experience is actually something that is very regular, except for some strange disjoints, or imperfections, that cause profound dissonance. Whereas, if you’re in the pure noise kind of range, it all feels blah, it all feels really close to neutral.

When we say the state of consciousness is highly symmetrical and such, you know, let’s say, 5-MeO-DMT, or jhanas, or something like that, we expect these to actually show up in many ways. If you look at the biorhythms, like heart rate and breathing, that’s going to show up, symmetry is going to show up in some ways, being a different kind of projection of the latent state. I mean, ultimately, the formalism, you know, this mathematical object corresponds to consciousness is not observable directly, at least not right now. So we have to kind of rely on these projections, these interpretations of what’s going on, these ways of getting at this unobservable, underlying state. And EEG, connectome harmonics, biorhythms, and so on, are different ways of getting at it. I’ll show you at least empirically that it’s all so far consistent with the Symmetry Theory of Valence.

Here’s kind of the big plan. All of these different projections of this underlying state. So we have basically this stimulus. These are kind of visualized also to give you an intuition. So there’s stimuli, basically more symmetrical stimuli with higher valence, then there’s the endogenous bodily state, you know, biorhythms, as well. The CNS State, the actual, okay, what’s going on in your brain, then the formalism, and then the phenomenology of valence. When you have high valence, we expect (and what we see is) that there’s symmetry all across the board, in each of these different ways of looking at the state of consciousness. In each of these projections of the latent state.

So I’ll go on and start with phenomenology. I know that phenomenology is such a tricky thing. It’s so difficult to do, right. It’s so difficult to do. You make a lot of mistakes in phenomenology, get confused, and become self-deceived. So I mean, hopefully, the observation I’ll relate to you is going to show you that at least we’re taking care of some of the failure modes of phenomenology.

So, first of all, we distinguish between intentional content and phenomenal character. So, if you smoke DMT, and you experience, you know, you say something like “I saw a dragon with my own eyes” that doesn’t mean there was actually a mind-independent dragon out there. And, you know, I take seriously your report that you saw a dragon, but I don’t know how significant that is necessarily. On the other hand, if you describe “Oh, and by the way, the dragon had scales that had a symmetry group of what’s called the glide mirror symmetry group, and it had a 17 hertz strobing effect“. Okay, yes, so we’re getting more into the phenomenal character. You’re actually describing what it felt like, not only what it was about. I would make the claim that these observations of symmetry being related to valence are about the phenomenal character. I don’t care that much about, you know, “What was the journey? What was the content of the experience?” I care more about what it felt like, what are the features of it, and what we observe is that there’s a deep connection here.

So I’ll just give you some examples. Basically, introspect. You know, the difference between massage and bodily pain. Massage is kind of this very, very pleasant, harmonious, tactile pattern throughout your body that gives you these very nice waves of pleasure, as opposed to bodily pain. Bodily pain, if you introspect on it, it’s almost kind of like there’s like pinch points and discontinuities and fragmentations and deformations in your sense of self and the continuity of your skin or your felt sense of your inner organs. Basically, I would make the claim that bodily pain always manifests in one way or another as a kind of symmetry breaking operation. Now, definitely keep this in mind if you ever have a pain again, hopefully not.

Also, let’s say anxiety versus relaxation. Anxiety, you could almost describe it as, constant prediction errors. “Oh, did my heart do something strange? Is my leg positioned properly?”. It’s a state of mind where all of these little imperfections bubble up to your awareness. I would say it’s interrupting the flow of your attention and creating these pinch points and deformations in the way you experience the world. As opposed to relaxation, where you’re almost kind of just completely melted into it. And it’s so regular, you can almost filter out most of your bodily sensations. And in that sense I would argue it has a very symmetrical quality.

There’s also this whole argument Mike brings up which is the phenomenology concerning non-adaptiveness, the non-adaptiveness principle, which is that basically, there’s a bunch of things out there that feel really good, but that weren’t in our evolutionary environment. Those are hints; we consider those hints that hey, if something wasn’t in the African savanna but feels great, it probably means that it’s kind of directly hacking into the patterns of valence somehow. We didn’t evolve to filter those out or to not get absorbed by them. And yeah, here are some examples, but I’ll go deeper into those. 

Now, there’s also this exotic valence. Bodily pain, anxiety, relaxations: those would be examples of “normal valence”. It’s the valence that we’re all used to. But I would say that also in “strange valences”, like valences in weird states of consciousness, they also follow this pattern. That in some sense, symmetry explains their pleasantness. And I’ll give you some examples.

So, dream music. I’ve had the pleasure or displeasure, you could say, of having had a lot of sleep paralysis and lucid dreams, and this effect is something you can experience in either sleep paralysis or lucid dreams. If you’ve had a lucid dream, where you were making music, or you heard, you’re hallucinating that there was a radio playing, you will notice that, “Oh my gosh, the music can be beautiful, like… incredible”. And this music, maybe you have heard it before, maybe not. Maybe your brain is generating it on the fly. But it has a quality to it that is extraordinarily hedonic and pleasant. And I remember studying this on myself over many lucid dreaming experiences. At first, I thought, “Oh my gosh, my brain is just unlocking this ability to create awesome harmonies and melodies”. But then I ended up realizing that even if I just make a kind of an “om”, this meditation sound, even though that sound is extremely simple, the quality of the sound in the lucid dream is profound. I mean, it’s almost kind of a surround sound, like 360 surround sound, and stereoscopic and full of reverb and richness. 

I would claim that it’s actually because, during a dream state, your brain is more resonant. You can kind of enter into these very, very resonant attractors, and it’s that quality that makes the music so compelling, not the melody. If you transcribe the melody, the melody may not be very significant. It was how it sounded that was so profound in the music in the dream.

Then you have meditation. Even these images, maybe, I don’t know if this is cheating, but representations of meditation, like high attainments, and so on, they usually come with these beautiful symmetries and whatnot. If you examine the phenomenology of jhanas, how they’re described, there seems to be kind of this projection of less and less information content in your experience. Going from having all of your attention concentrated in one point to then the experience of completely perfectly smooth, boundless space to then just pure consciousness, and then the experience of neither nothing nor something. In a sense, that’s kind of approaching the limit of zero information. And then people report these jhana experiences, they’re not pleasant in a conventional sense. It’s not like eating ice cream or something like that, but they’re still very, very high valence. They’re blissful, in an exotic way. But, I do want to point out that there’s this fascinating, strange relationship here between low information content and the blissfulness and the healing quality of the state.

And then there is exotic valence from psychedelics. I mean, again, I don’t want you to focus on the intentional content, what was the experience about. What you thought, of course, can influence your valence, but it’s more about the phenomenal character. There’s this phenomena of tracers, you move your hand around, and you see copies laying around, and in a sense, it’s giving a temporal depth to your experience. It’s almost kind of adding a new dimension of time, where qualia can pile up. And usually, if the trip is good, you’ll notice that these tracers are in a harmonic relationship with each other. That is kind of the essence of what makes them feel so good.

Likewise, there’s a psychedelic texture repetition. You stare at a piece of grass on LSD, and it starts to symmetrify. And I would totally say this is exotic valence because you ask the person, and they will say “the ground was symmetrifying, and I don’t know why, but it was awesome”. There was something really cool about it, and why would that be? Our interpretation here is that psychedelics are, in a sense, unlocking the valence capacity of your visual cortex. It’s kind of transforming your cortex into a pleasure machine, basically allowing it to exhibit these profound symmetries, and that is what actually is making them feel so compelling. People will struggle to explain “Why were the visuals cool? Why were they interesting?”. When it comes down to it, I think it is the symmetry.

Interestingly, these are called the wallpaper symmetry groups. There’s 17 possible ways of tessellating a two dimensional space. From subjective reports, we know that any of these can be experienced on a psychedelic. The ground, kind of chaotically, will arrive at one attractor of symmetry. It could be any of these 17, and they all feel great. They’re all extremely aesthetic and beautiful and blissful in one way or another. But it’s kind of a testament to just how general this effect is.

I would make the claim, and this is obviously a strong claim, but it matters for something like therapy, psychedelic therapy. We recently saw this fascinating research on psilocybin for major depression, and that a lot of these effects are mediated by whether you had a mystical experience or not. I would say that if you did have a mystical experience, and it was healing, I would bet that while you were having that experience, the sense of space and time was basically extremely, extremely symmetrical. And here is kind of why it’s so confusing. Because you come back and you say, “Well, I saw Jesus”, and you think that you got healed because of Jesus. I don’t want to dissuade you from that view, but I would basically ask you “Okay, but when you experienced Jesus, what was the feeling of space and time?”. They might say something like, “Oh, it had a beautiful light. It had this beautiful harmony and rainbows”. And I’ll claim that if you introspect on them then that it’s actually the quality of phenomenal space and time that is healing and blissful. The meaning, the religious meaning, is something that is helping your mind basically concentrate on that space, and take it seriously as a way of propagating this negentropy in your nervous system.

Now, another place where this shows up super, super clearly, phenomenologically, is on DMT. I definitely recommend this article we wrote that basically charts the DMT space. You can know a lot about where you are in the DMT space by describing what is your energy level on the one hand, and then what is the information content on the other. I would say DMT states that have close to zero information content would be kind of these geometric, perfectly repeating, symmetry groups, either 2D or 3D. Whereas, more chaotic states would be kind of in the middle. The energy level would be a matter of dose. The “height” you reach is very, very dose-dependent. But then the valence, I think it’s very, very dependent on actually where in the axis of information content you find yourself in.

Here again, there’s this diagram that the most blissful experiences you may have on DMT are going to be on these kinds of honeycombs and perfectly symmetrical patterns. The most unpleasant experiences are going to be just right next to those, they are going to be kind of dissonant honeycombs. Whereas you know, when you get to complex narratives, like machine elves and alien realms and all of that stuff, those experiences would be very mixed in their valence. There’s both dissonance, consonance, symmetry, anti-symmetry; those are very complex experiences.

Now, the information content, we think of them as basically attractors in feedback systems. You may end up in a chaotic attractor, you may end up in a limit cycle or a fixed point. And that will determine how much information content the state has. 

Interestingly, this also can be used to describe the difference between DMT and 5-MeO-DMT. We think DMT tends to have a lot more information content. 

So you have these very rich patterns, and I would say competing synchronies. On DMT, there’s all of these slightly different frequencies that are competing for your attention and creating a narrative out of that. That is like a very mixed experience; it is both blissful and distressing at the same time.

Whereas 5-MeO-DMT, which is described as far more powerful emotionally, tends to give you this sense of pure space, like the feeling of the insight into emptiness, the feeling of infinite boundless consciousness, very little information content. Yet, it’s so emotionally impactful to such an extreme extent.

Interestingly, I would say, the reports do come out that on 5-MeO-DMT, you may have the best experience of your time, or you may have the worst experience of your life. It’s kind of bimodal. It’s either amazing or it’s extremely bad. Often, it starts out really bad and then it gets amazing. I would describe that in terms of kind of this annealing process where it basically starts with dissonance, and, over time, things synchronize, and you do end up where all of your nervous system is entrained to the same frequency, and that feels very, very blissful. Whereas DMT is always kind of in this mixed state. It is very difficult for DMT to be pure negative or pure positive. It’s always this mixed state. So I would say, yeah, this is kind of the phenomenological case for the Symmetry Theory of Valence.

I’m two thirds of the way through the presentation. I’m just gonna walk you through the empirical evidence. So we were talking about phenomenology; that’s one of the projections of this formalism and its symmetry. There’s symmetry in the formalism. It’s gonna manifest in some forms of phenomenological symmetry. Likewise, you know, if you use external stimuli in order to generate a state, like, let’s say, watching a movie, playing music, playing stroboscopic stimulation, there’s a lot of evidence that indicates that the symmetry of the stimuli is the leading factor for how pleasant or unpleasant the resulting state is. We have all of this research in vision.

These are just some examples. It’s so stunning, right? Even if you know the effect, you still get the valence response. You go to a cathedral and think “Okay, I’m not gonna get high valence, I’m not going to get high valence”. You still get the response. It’s pretty automatic. As long as it has this rich, deep symmetry, oftentimes, it’s going to be very beautiful. There’s something very compelling about this.

Just some random pictures to give you a sense of this.

Why does this feel good? It really has very little to do with our ancestral environment.

Anyway, this is such a robust effect that, with the symmetry of faces, for example, even face paint can be used to modify the valence. So, if you don’t have a perfectly symmetrical face, but you add symmetrical face paint with beautiful patterns, you’re going to be judged as more beautiful. It’s just such a strong effect, that it can actually modify your perception of how beautiful somebody is. Likewise, if you add asymmetrical patterns, you look less beautiful. Now, this, I wouldn’t say this is that strong of evidence because this actually does have an evolutionary reason. Symmetry in faces is a marker of mutational load. So I don’t put that much stock in, symmetry of faces being that relevant. But symmetry in other forms is where I think it’s so stunning. 

You also see this in symmetry in audio, basically, regular rhythms. Harmony is the leading predictor for whether a sound is going to be pleasant or unpleasant.

You know, this is Helmholtz’s big idea. He was the first one to figure out why playing two notes in a piano that are one semitone apart feels unpleasant. It’s because the harmonics are basically within what’s called the critical window. They generate beat patterns and the beat patterns can be described as basically symmetry breaking operations in the waveform. Those symmetry breaking operations, in essence, cause irritation. So basically, the more beating there is in sound, and the more beating across the spectrum, the more irritating and distracting and rough the sound is going to sound like. Whereas, when you have these harmonic relationships, you play one note, one piano note, and another at an octave of difference, the harmonics line up perfectly. Actually, the sound is very compressible because you don’t have this extra information of where all the other harmonics lie. They’re just the harmonic sequence. And that is universally described as a more pleasant sound.

When you add up all the harmonics, you get these interesting curves. The height here is the amount of dissonance. When you have a relationship of one to two, basically an octave, you have zero dissonance, and that feels really good. Now, music is very complicated. We have to factor in the boredom mechanism. If you just play the same octave over and over, you get bored, and there’s an inner sense of restlessness and dissonance. But if you just hear it for the first time, then there’s a super, super strong relationship between symmetry and valence.

These are just examples of a piano chord.

Dissonant sounds. I can send you a link to all of these sounds after the presentation*, but I have some links for a SoundCloud account where you can kind of get convinced that “Oh gosh, these are actually really bad sounds”. It’s not that I’m saying they’re bad. If you ask 100 people, like 99% of people will say they’re awful. 

Likewise, reverb basically symmetrifies any waveform. Reverb is almost kind of this hack that you take almost any dissonant sound and you add reverb to it and is going to sound a lot less bad, a lot less distracting, irritating, and so on. So this is comparing the sound of a baby crying, which by the way, like in our analysis, it shows that babies crying, it’s almost like their sound is optimized for dissonance. It’s almost kind of as dissonant as it gets for a sound made by a human. For good evolutionary reasons, it has to be distracting, and catch your attention, bring the desire to stop it. But you add reverb and to give you a sense, that’s like if the baby was in a huge cave, you get all these echoes averaging out the beat patterns. It sounds way better, way less distracting, probably not good from an evolutionary standpoint. But, it’s just a fascinating kind of transformation you can apply to any waveform.

And here, I just want to illustrate that valence can happen across the spectrum. So I also have this file**, and you’re welcome to listen to it after the presentation where you can have consonance anywhere in the spectrum, mixed in with dissonance anywhere in the spectrum, mixed in with noise anywhere in the spectrum. That ends up basically creating these very mixed states. 

So basically, when I say “Oh, I had a mixed experience, a mixed valence experience” that underdetermines what I experienced because we don’t know if the positive part was in the high frequencies or in the low frequencies. We don’t know that. That’s why the full picture of valence would also include the spectrum for positive, negative, and neutral valence. You can have high frequency pleasure, you can have low frequency pleasure, etc. So that kind of explains why there’s a tremendous diversity of possible mixed experiences even though ultimately they’d still come down to symmetry. Deep down, they can all still be explained with symmetry.

Now, endogenously generated symmetry, this is fascinating research. That when you have this “biorhythm coherence” you feel happier. And the way of computing biorhythm coherence is very related to musical consonance. Breathing entrained with heart rate variability is reported as giving rise to a just much, much better positive mood, and is one of the things that long-term meditation achieves. Meditation entrains these biorhythms and basically makes them interlock with one another. That is reported as giving rise to positive mood which is an interesting finding and very consistent with STV.

Here are just some quotes. Cool.

And you know, the heart palpitations. I mean, it’s similar to anxiety in that if you have like this usually regular metronome, and it’s failing, is generating these imperfections, that gives rise to unpleasant states of mind. I’m sure heart disease is terrible for your valence. Likewise, meditation is a wonderful tool for heart disease because it allows you to overcome those imperfections and still feel good despite the problem.

In terms of other endogenously generated symmetry, I will mention orgasm and flow. Orgasm is a powerful generator of endogenous resonance. It’s the entrainment of motor systems to near hallucinations, to synchronizing feedback processes across multiple functional networks. With an orgasm, there’s a deep, deep level of synchrony and symmetry across the nervous system. I highly recommend introspecting on this (not to get into your sex life or anything, though). I mean, it’s something you can actually pay attention to, and it becomes very obvious once you notice it. 

Likewise with flow, there’s this evidence that symmetry is deeply related to flow. Two physiological metrics for measuring flow are cortical muscular coherence and a degree of coupling between neural EEG waves and EMG oscillations of muscle activity. So, there’s also these interlocking patterns, lower information content, more symmetry. Yeah, it’s a strong predictor of flow. So like, hey, go figure flow is also symmetrical.

Okay, let’s get into the symmetry in the brain. So this is kind of the other projection you could take of the latent state. If you look at the central nervous system of high valence states, how does the valence show up? And, you know, meditation, like all over the place, basically pretty much any kind of meditation, if done for a long enough time, leads to some kind of EEG coherence. Whether it’s gamma coherence, delta coherence, or alpha coherence, depends on which kind of meditation you do. But they all generate some form of coherence, and coherence in EEG is intimately related with symmetry. I mean, basically, two signals are coherent when they’re both reflections of a shared signal through a reverb pattern, meaning that they’re encoding the same information just through a different filter, which is, again, deeply, deeply connected to symmetry. 

Here’s a fascinating study from 2019 that I recommend reading which to me was really stunning. It was stunning in just how clear the connection with the Symmetry Theory of Valence was. The study is about the EEG recordings of the first and second jhanas and the interesting patterns that emerged in them. One of them is this seizure-like activity. Now, seizure-like activity is three to five hertz, and it doesn’t have harmonic structure. I mean most seizures don’t have their harmonics together with them. But the type of seizure-like activity you see on jhanas does have harmonic structure. And the picture here is basically the Fourier transform of the independent components of the EEG recordings. You can see there’s a very clean 5.6 hertz signal, together with its harmonic of 11.23 hertz. This is kind of stunning. Why would this happen? And jhanas feel really blissful. Without the Symmetry Theory of Valence, this is just super surprising and strange. With the Symmetry Theory of Valence it’s like, “Oh, yeah, you’re, feeling a really great symmetrical attractor of your brain and sustaining it”. So that’s going to feel good. 

Even you know, ketamine showing high levels of a gamma coherence.

For 5-MeO-DMT, the only dataset I’m aware of, of EEG and 5-MeO-DMT, shows coherence across the spectrum, not only gamma coherence, but also beta coherence, and especially delta coherence. Again, why on earth? The Symmetry Theory of Valence would explain this. It would say, “Yes, this is expected”. Other theories might struggle a bit. Now, I’ve got to say that just because you have high coherence doesn’t mean it’s going to be high valence. We expect also very negative valence could also be high coherence. Except that when you have total coherence, then we expect that to be always positive valence. Again, it’s going to have that relationship because you could still have a high average coherence, but have half of your channels coherent in a certain frequency and half of the other channels coherent in a slightly different frequency. That might actually maximize dissonance. So just average coherence is not enough. You also need to tell whether it’s in harmonic structure or not.

Pleasure in the brain seems to be kind of this distributed effect that also from our point of view would mean it’s actually a whole brain phenomena. 

This is about what I was mentioning about the pleasure centers from our point of view. I mean, there’s this research of if you tried to synchronize clocks, and you tried to synchronize neurons, and you put them in a geometric grid. If it’s large enough, you’re not going to usually get full scale synchrony. You might have emergent patches of synchrony or traveling waves of synchrony. But if you also add these random connections across the network and reduce the synaptic path length, then you can unlock the ability for the entire network to enter synchrony. So we think of the pleasure centers as kind of these bridges that are, in a sense, lowering the average synaptic path length across your brain, and therefore enabling similar synchrony across the brain. And that’s the reason why we think the pleasure centers generally feel good when you activate them. 

Okay, getting to the end of the presentation. So I’ll just talk about a few near “enemies”. I put “enemies” in quotes, because we actually admire these people. They’re part of our research lineages. I think they’re a very, very key component of any good theory of consciousness. But I think when it comes to valence itself, there’s some explanations in the space that are really close to the Symmetry Theory of Valence, but they’re not exactly what we’re getting at. So there’s this whole account of computational efficiency. The brain likes computational efficiency, but in a sense, you still have to explain why the brain likes computational efficiency- what does this liking manifest as? We use this argument of “passing the bucket” which ideally your theory of valence should avoid. The theory should explain what valence itself is, not only when it gets triggered. These theories of computational efficiency, energy efficiency, we would claim, they’re telling you under what conditions positive valence gets triggered, but they don’t tell you what positive valence itself is. And that’s what the Symmetry Theory of Valence is getting at. 

So yeah, these are some of the issues with those, at least as complete theories.

Finally, okay, counter examples. There’s this whole theory I recommend reading called Neural Annealing (by Mike Johnson). But even very neutral energy that neither has harmony or dissonance, can still give rise to very positive feelings because it can give rise to this annealing process. And that’s actually what we believe is going on with psychedelics. Psychedelics gives you what Mike would call semantically neutral energy. And that gives rise to basically this entropic disintegration, a term from Robin Carhart-Harris and the entropic brain hypotheses, which then gives rise to kind of this search, or self-reorganisation that basically will settle on these basins of symmetry. And it’s those that feel good, not the energy that feels good. It is the end result, the attractor that it takes you to.

And this explains, I think, why even somebody can like hot sauce. Hot sauce is kind of this unpleasant stimuli, but it can lead to euphoria. It can lead to this heightened state of energy. If you introspect on the euphoria of hot sauce, it’s not the unpleasant pain in the mouth, it’s that it raises all of your energy, your entire amount of the intensity of your consciousness. You can then notice these resonant waves, and it is those resonant waves that feel good, not the hot sauce itself. So there’s this kind of a step that basically separates one from the other.

I’ll just very quickly, briefly describe one way we’re trying to test the Symmetry Theory of Valence. It is not the only way to test it. I would even argue that, you know, the argument that I here presented is itself a potentially strong argument. But ideally, you know, we generate novel predictions. And this is one of them, which is that we basically expect that the very positive states of consciousness will have a harmonic relationship, basically a consonant relationship between the brain harmonics. Yeah, using the work of Selen Atasoy.

This algorithm of quantifying the amount of consonance in brain harmonics, which is something we were working with, and hopefully will get resolved soon.

We anticipate that, again, if this is true, the Symmetry Theory of Valence would be validated. If it’s not, it doesn’t invalidate it, because there’s many ways in which it can manifest. But when you have harmonics that are in a consonant relationship with each other, and those are the main drivers of your experience, we expect that to be pleasant.

That is, euphoric.

Whereas, when you have harmonics that are dissonant with each other, they generate these intense beating patterns. So we expect that to be described as unpleasant. Again, we don’t know, but we want to check if this is true. 

Just a couple testable predictions based on this, which is that we expect psychedelics to enhance the range of valence. Basically, psychedelics enhance energy across the board. Just all of the harmonics have more energy. We expect that some of those combinations will be just very consonant and reported to be very pleasant, some of those will be very dissonant, reported to be unpleasant. Then SSRIs, there’s a lot of research on SSRIs and their blunting effects. They cut the extremes of valence. So, we expect when it comes to harmonics that the SSRIs will be more noisy, less consonant, less dissonant. MDMA, we expect it to be a stable attractor of a few resonant modes that are very consonant with each other. Stimulants would be kind of high frequency consonance. Opiates would be low frequency consonance. Again, this idea that you can be in a good state leaves underdetermined whether there are symmetries in the high frequencies or the low frequencies, and this would disentangle these types of mixed experiences.

These are the last two or three slides which is kind of a case study which is SSRI’s. Roughly speaking, we interpret them as being noise inducers which is why things like orgasm on SSRIs are less intense. Crying is hard. I mean, crying itself is a kind of a dissonant and sometimes consonant, kind of resonant state. On SSRIs you feel kind of spaced out and music enjoyment goes down. So yeah, the way we think of SSRIs is that they’re almost kind of like listening to a white noise machine along your life, so it’s gonna cut off the extremes. It’s gonna blunt both very positive and very negative valence, and it’s gonna just kind of center you in neutral valence.

Whereas psychedelics, they basically kind of purify and intensify your harmonics. And in that sense, you get to have more pleasant and more unpleasant states and both extremes.

Just to remind you: introspect. I compel you, next time you’re on a psychedelic having a mystical experience, introspect on the quality of space and time. I suggest that you will probably be experiencing these kinds of beautiful ripples that are in a harmonic relationship to each other. Please email me if this is true or not true. But that’s the experience so far. And that’s the reason why this can feel so amazing. 

The future of mental health, ideally, would be that we can identify, “what are the sources of dissonance in your nervous system?” and then find the shortest path to the smallest change possible that will give rise to sustainable consonance in your nervous system. Whether this is going to be with meditation, a psychedelic session, or yoga, or biofeedback will be person-specific. There’s probably a shortest path from a highly dissonant dysfunctional state to a sustainable consonant state for each person.

And with that I just want to say thank you to other people in the team of QRI. And thank you, Robin, Shamil, and all of you guys for attending this presentation. And to the Centre for Psychedelic Research for hosting this presentation.

Thank you so much.


* BART sound, Baby Crying, Baby Crying w/ Reverb

** Consonance – Noise – Dissonance – Mixed Spectra


Special Thanks to: Mike Johnson who initiated this research direction and has been deeply involved in it for years. To Andrew Zuckerman, Quintin Frerichs, Kenneth Shinozuka, Sean McGowan, Jeremy Hadfield, and Ross Tieman for their contributions to the current work this year. To everyone in the team for their help, support, and love. To our donors for their incredible help. And to you, dear reader. Thank you!

The QRI Ecosystem: Friends, Collaborators, Blogs, Media, and Adjacent Communities

The Qualia Research Institute has the vision of a world free from involuntary suffering in which conscious agents are empowered to have full control over their lived experiences. Its mission tackles this objective by combining foundational research on consciousness with a focus on explaining the mathematical properties of pleasure and pain for a full, formal account of valence.

By relating our mission to existing memeplexes, we could perhaps accurately describe the ethos of QRI as “Qualia Formalist Sentientist Effective Altruism“. That’s a mouthful. Let’s break it down:

  • Qualia Formalism refers to the notion that experience has a precise mathematical description that ties it with physics (for a more detailed breakdown see the Formalism section of the glossary).
  • Sentientism refers to the claim that value and disvalue are entirely expressed in the nature and quality of conscious experiences. In other words, that the only reason why states of affairs matter is because of the way in which they impact experiences.
  • Effective Altruism refers to the view that we can aspire to do the most good we can rather than settle for less. If you examine the actual extent to which different interventions cash out in terms of reduction in suffering throughout the world, you will notice that they follow a long-tail distribution. Thus, research on how to prioritize interventions really pays off. Focusing on the top interventions (and being willing to spend extra time digging for even better ones) can multiply your positive impact by orders of magnitude.

We could thus say that people and organizations are more or less aligned with QRI to the extent that they are aligned with each of these notions and their combinations thereof. More so, QRI also values the practice of rational psychonautics and the study of one’s own mind with meditation – hence we also include lists of rational psychonauts and great dharma teachers.

Find below the list of people and organizations that have a significant degree of alignment with QRI on each front. We also include a list of blogs and websites from readers of our work, which is meant to incentivize community-building around the aforementioned core ideas.

Format:

Name of Person/Organization – Blog/Website/Media [if any] (Representative Post of the Author- Sometimes Not from Their Primary Site [if any])


QRI Canon

Qualia Research Institute – QRI (Glossary)

Michael Edward Johnson – Open Theory (Neural Annealing)

Andrés Gómez Emilsson – Qualia Computing (Wireheading Done Right)

Current and Former QRI Employees and Collaborators Who Write About QRI Topics

Romeo Stevens – Neurotic Gradient Descent (Core Transformation)

Quintin Frerichs – The Youtopia Project (Wada Test + Phenomenal Puzzles)

Andrew “Zuck” Zuckerman – andzuck.com (Super Free Will)

Kenneth Shinozuka – Blank Horizons (A Future for Humanity)

Wendi Yan – wendiyan.com (The Psychedelic Club)

Jeremy Hadfield – jeremyhadfield.com (How to Steal a Vibe)

Elin Ahlstrand – Mind Nomad (Floating Through First Fears)

Margareta Wassinge and Anders Amelin – Qualia Productions (When AI Means Advanced Incompetence)

List of current and former QRI collaborators and volunteers not listed above (in no particular order): Patrick Taylor, Hunter Meyer, Sean McGowan, Alex Zhao, Boian Etropolski, Robin Goins, Bence Vass, Brian Westerman, Jacob Shwartz-Lucas.


People and Organizations that Advocate for Sentientism and the Elimination of Suffering

David Pearce – Hedweb.com (The Hedonistic Imperative)

Manu Herrán – manuherran.com (Psychological Biases that Impede the Success in the Reduction of Intense Suffering Movement)

Jonathan Leighton – jonathanleighton.org (Why Access to Morphine is a Human Right)

Magnus Vinding – magnusvinding.com (Suffering-Focused Ethics: Defense and Implications)

Robert Daoust – robert.algosphere.org (Review of Precursor Works)

Jacob Shwartz-Lucas – Invincible Wellbeing (Pleasure in the Brain)

Algosphere Alliance – algosphere.org (Vision)

Organization for the Prevention of Intense Suffering (OPIS) – preventsuffering.org (Cluster Headaches and Potential Therapies)

Sentience Research – sentience-research.org (Algonomy)

People and Organizations Aligned with Qualia Formalism

Giulio Tononi – integratedinformationtheory.org (Phi: A Voyage from the Brain to the Soul)

Steven Lehar – slehar.com (Harmonic Resonance Theory)

Jonathan W. D. Mason – jwmason.net (Quasi-Conscious Multivariate System)

Johannes Kleiner – jkleiner.de (Mathematical Consciousness Science)

Dan Lloyd – Labyrinth of Consciousness (The Music of Consciousness)

Luca Turin – A Spectroscopic Mechanism for Primary Olfactory Reception (The Science of Scent)

William Marshall – Google Scholar (PyPhi)

Larissa Albantakis – Google Scholar (Causal Composition)

Models of Consciousness Conference – models-of-consciousness.org (YouTube channel)

People and Organizations Aligned with Effective Altruism

Nick Bostrom – nickbostrom.com (What is a Singleton?)

Anders Sandberg – aleph.se (Uriel’s Stacking Problem)

Toby Ord – tobyord.com (The Precipice)

80000 Hours – 80000hours.org (We Could Feed All 8 Billion People Through a Nuclear Winter)

Future of Humanity Institute – fhi.ox.ac.uk (Publications)

Future of Life Institute – futureoflife.org (AI Alignment Podcast: Identity and the AI Revolution with David Pearce and Andrés Gómez Emilsson)

Center on Long-Term Risk – longtermrisk.org (The Case for Suffering-Focused Ethics)

Rethink Priorities – rethinkpriorities.org (Invertebrate Welfare Cause Profile)

Happier Lives Institute – happierlivesinstitute.org (Cause Profile: Mental Health)

Effective Altruism Forum – forum.effectivealtruism.org (Logarithmic Scales of Pleasure and Pain)


Rational Psychonautics

Steven Lehar – slehar.com (The Grand Illusion)

James Kent – psychedelic-information-theory.com (The Control Interrupt Model of Psychedelic Action)

Alexander Shulgin – Shulgin Research Institute (Phenethylamines I Have Known And Loved)

Thomas S. Ray – Breadth and Depth (Psychedelics and the Human Receptorome)

Matthew Baggott – Beyond Fear: MDMA and Emotion (MDA and Contour Integration)

Psychonaut Wiki – psychonautwiki.org (Visual Effects)

Psychedelic Replications – reddit.com/r/replications (Best of All Times Replicationsspecific floor tile example)

Great Dharma Teachers

Daniel M. Ingram – Integrated Daniel (No-Self vs. True Self)

Leigh Brasington – leighb.com (Right Concentration)

Shinzen Young – shinzen.org (The Science of Enlightenment)

Culadasa – culadasa.com (Joy and Meditation)


QRI Friends and Supporters

Ryan Ferris and James Ormrod – The Good Timeline  (5-MeO-DMT, Paradise Engineering)

Adrian Nelson – Origins of Consciousness (Consciousness Blindness in Science Fiction)

Alex K. Chen – Quora (What are the long term effects of Adderall, Dexedrine, or Ritalin use?)

Andy Vargas – Neologos (Praxis for Open Individualism; Purpose Statement)

Tyger Gruber – tygergruber.com (The Show)

Jacob Lyles – Jacob ex machina (Building a Better Anti-Capitalism)

Adjacent Communities, Organizations, and Allies

Scott Alexander – Slate Start Codex (Relaxed Beliefs Under Psychedelics and the Anarchic Brain)

Geoffrey Miller – Primal Poly (The Mating Mind: How sexual choice shaped the evolution of human nature)

Zvi Mowshowitz – Don’t Worry About the Vase (More Dakka)

Sarah Constantin – Multiple websites: 12, 3 (More Dakka in Medicine)

Scott Aaronson – scottaaronson.com/blog/ (Why I Am Not An Integrated Information Theorist)

Gwern – gwern.net (Iodine and IQ Meta-Analysis)

Venkatesh Rao – Ribbonfarm (Why We Slouch)

David Chapman – meaningness.com (Romantic Rebellion)

Atman Retreat – atmanretreat.com (FAQ)

Foresight Institute – foresight.org (YouTube Channel)

Convergence Analysis – convergenceanalysis.org (List of Works)

Simulation Series – About (YouTube Channel)

Consciousness Hacking – cohack.org (blog posts)

HeartMath Institute – heartmath.org (Chapter on Coherence)

The Wider World of People Who are Friends and Acquaintances of the QRI Ecosystem

Note: I asked (on social media) our readers to share their blogs and personal sites with us. Some of these links are very aligned with QRI and some are not. That said, together they represent a good sample of the memetic ecosystem that surrounds QRI. Namely, these links can be taken as a whole to be suggestive of “the memetic ground upon which QRI is founded”. Please feel free to share your blog or personal site in the comment section of this post.

Jack Foust – Welcome to the Symbolic Domain

Scott Jackisch – Oakland Futurist (Art as a Superweapon)

Maurits Luyben – Energy and Structure

Anonymous – deluks917 (What does ‘Actually Trying’ look like?)

Sameer Halai – sameerhalai.com (Toilet Paper Shortage is Not Caused by Hoarding)

Yohan John – neurologism.com (Some Wild Speculation On Goodhart’s Law And Its Manifestations In The Brain)

Jamie Joyce – The Society Library (Deconstructing the Logic of “Plandemic”)

João Mirage – YouTube Channel (The Mirror of the Spirit)

Natália Mendonça – Axiomatic Doubts (What Truths are Worth Seeking?)

Dustin Ali Francis Janatpour – Tales From Samarkand (The Inspector and the Crow)

Zarathustra Amadeus Goertzel – zarathustra.gitlab.io (Garden of Minds)

Duncan Sabien – Human Parts (In Defense of Punch Bug)

Brenda Esquivel – Abanico de Historias (La Reina Tamar y el Pájaro Condenado)

Vishnu Bachani – vishnubachani.com (Latent Possibilities of the Tonal System)

Martin Utheraptor Duřt – utheraptor.art (Psychedelic Series)

Qiaochu Yuan – Thicket Forte (Monist Nihilism)

Jedediah Logan – Medium Account (Coping with Death During the COVID-19 Crisis)

Eliezer da Silva – eliezersilva.blog (Prior Specification via Prior Predictive Matching)

Cassandra McClure – Lexicaldoll (On Save States)

Gaige Clark – mad.science.blog / Querky Science (The Phoenix Effect)

Ben Finn – optima.blog (Too much to do? Plan your day with Hopscotch [longer])

Michael Dello-Iacovo – michaeldello.com (How I Renounced Christianity and Became Atheist)

Robin Hanson – Overcoming Bias (What Can Money Buy Directly?)

Katja Grace – meteuphoric.com, Worldly Positions, AI Impacts

Mundy Otto Reimer – mundyreimer.github.io (On Thermodynamics, Agency, and Living Systems)

Khuyen Bui – Medium Account (Beyond Ambition)

Jessica Watson Miller – Autotranslucence (Art as the Starting Point; Becoming a Magician)

Aella – knowingless.com (The Trauma Narrative)

Jacob Falkovich – Put a Number on It (The Scent of Bad Psychology)

Javi Otero – iawaketechnologies.com (Fractal Entrainment: A New Psychoacoustic Technology Inspired by Nature)

José Luis Ricón – Nintil

Eliot Redelman – BearLamp

Tee Barnett – teebarnett.com (Are you a job search drone?)

Juan Fernandez Zaragoza – filosofiadelfuturo.com (Pandemia de Ideas)

Eric Layne – (The Antidote to a Global Crisis)

Kazi Adi Shakti – holo-poiesis.com (Beyond Affirmation and Negation)

Pushan Kumar Datta – kaiserpush1 (Ramayana and Cognition of Self)

Yan Liu – Inflection Point (Seeing a World Unshackled from Neoclassical Economics)

Joseph Kelly – (Entrepreneurship is Metaphysical Labor)

Logan Thrasher Collins – logancollinsblog.com

Malcolm Ocean – malcolmocean.com (Transcending Regrets, Problems, and Mistakes)

Jesse Parent – (Why ‘Be Yourself’ is Still Excellent Relationship Advice)

Milan Griffes – Flight From Perfection (Contemplative Practices, Optimal Stopping, Explore/Exploit)

Cody Kuiack – cosmeffect.com (The Holomorphic Self – Meditations)

Daniel Eth – thinkingofutils.com (Quantum Computing for Morons)

Brian P. Ellis – brianpellis.net (Refuting Dr. Erickson and Dr. Massihi)

John Greer – johncgreer.com (The Three Buckets)


Finally: List of Other Relevant Lists

Effective Altruism Blogs – eablogs.net

LessWrong Wiki – List of Rationalist Diaspora Blogs

Effective Altruism Hub – effectivealtruism.org (Resources)

Open Individualism Readings – r/OpenIndividualism (Wiki Reading List)

Phenomenal Binding Resources – binding-problem.com

Physicalist Hotlinks – physicalism.com/physicalist-hotlinks

QC Coronavirus Edition: Preventing Pandemics by Living on Toroidal Planets and Other Cocktail Napkin Ideas

Here is what we’ve gotta do.

I want every strategy we’ve got on Near Earth Object Collision, OK?

Any ideas, any programs, anything you’ve sketched on a pizza box or a cocktail napkin…

Armageddon (1998 film, when NASA realizes that there are 18 days left before the asteroid hits the Earth)

This Whole Thing

On January 20th someone shared, in a facebook group that I’m a part of, four facts about an emerging viral infection in China: (1) high death rate, (2) high contagion rate, (3) long incubation periods, and (4) the fact that it appeared uncontained. Despite the (at the time) relatively low number of cases, those four facts did not seem to paint a pretty picture of what was about to happen.

This was immediately alarming to a lot of people in my circles, and for good reason. Matthew Barnett, Justin Shovelain, Dony Christie, and Louis Francini sounded alarms as early as mid-January, and the rest of the EA and rationalist cluster followed suit. It makes sense people in this cluster would be concerned early on, as many of them have looked at global catastrophic risk scenarios for years, and were already well aware that the world was unequipped to deal with an infectious disease with all of the above four properties. Pandemic preparedness programs have so far relied on luck. For instance, in his 2015 TED talk “The next outbreak? We’re not readyBill Gates uses as an example the 2013 Ebola outbreak: “The problem wasn’t that there was a system that didn’t work well enough. The problem was that we didn’t have a system at all.” Accordingly, that particular outbreak didn’t become a disaster because of sheer luck: the disease only becomes contagious when you are already very sick and it didn’t hit a major urban area, so containing it was possible. But this time around we don’t seem to have the same luck.

Since, I’ve seen many thought leaders I respect succumb to focusing on this topic: Robin Hanson, Eliezer Yudkowsky, Paul Graham, Tyler Cohen, Sarah Constantine, Scott Alexander, Scott Aaronson, Joscha Bach, Ryan Carey, William EdenRobert Wilbin, etc. etc. Not to mention the way these people are publicly responding to each other and building a parallel narrative on a higher level of complexity than most everybody else****. These and many other well respected intellectuals have been going on and on about the situation for over a month now. An exponentially growing curve in its early stages may not be alarming to most people, but it certainly was to people like this (Ps. 3Blue1Brown, Kurzgezagt, and Mark Rober also recently joined the conversation).

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Image by Evan Gaensbauer (March 2020 Dank EA Memes banner)

This all adds up to a vibe of countdown to Armageddon: “X days until hospitals are overwhelmed, Y days until a million people die, Z days until a vaccine will be found”. In line with this perceived, if not frighteningly real, urgency, we’ve seen countless facebook groups, subreddits, and forums scouting for novel ideas and projects to help above and beyond what the governments of the world are already doing (e.g. Covid19RiskApp, Give Directly Response, Covid Accelerator [of technology to decelerate the spread [possibly a terrible or brilliant branding]], List of Predictors, and Corona Variolation).

march_19_2020_spread_pandemic

As of March 20 2020

I personally gave a lot of thought to pandemics several years ago (in college I was on the fence between working on pandemic prevention and consciousness research as a career), so my immediate thought when learning about the virus and its properties was “we are screwed, this can’t be contained with how the world is currently set up”. While containment might have been possible at the very beginning with some luck, it very quickly becomes unmanageable. That said, I’d like to explore here ways in which the world could be realistically modified in order to contain, mitigate, and ultimately reverse the spread of novel contagious diseases including this one. After all, the WHO director general said on March 9th: “The rule of the game is: never give up.” So, well, let’s give it some more thought. I hence offer my ‘sketches on a cocktail napkin’ type of ideas in case they find any application:

Introduction

Let us start by breaking down “social networks” into (1) contact networks, and (2) information networks:

  1. Contact networks are weighted undirected graphs where each node is a person and each edge encodes the frequency and intensity of the contact between the people it connects.*
  2. Information networks are weighted directed graphs that encode the amount of information transmission that there is between pairs of people. To a large extent, contact networks are subsets of information networks.**

Contact networks are what matters for modeling infectious disease transmission. Despite the constitutionally granted freedom of assembly, one can posit that if the risks to the public are high enough, it is justified to place some constraints on the nature and properties of contact networks. In a free society that truly grasps the danger of pandemics and is determined to squash them at the very beginning, contact networks might require some degree of top-down control. Perhaps, if we are serious about future pandemic prevention, we could re-conceptualize freedom of assembly as pertaining to information, rather than contact, networks.***d3297191270ea5bca8db652e977a6d57

So in what ways could a contact network be pandemic-safe? As an intuition pump for what I’ll be discussing further below, I’d like you to consider what it might be like to live in the original “HaloRingworld (and Ringworld too). Assume that unrestricted travel in Halo is limited to land roaming with a maximum speed, and that in order to use a spacecraft or tube across an arc of the circle, you need to be thoroughly tested and quarantined in-between. With these constraints, we would naturally infer that the structure of the contact network of the people in this world would be embedded in the ring itself. Meaning that if an infectious disease originates somewhere on the Ringworld, containing its spread would be as easy as blocking movement on two small fronts around the epicenter of the outbreak. This even allows you to control and ultimately fully suppress diseases with long incubation periods. It is a matter of estimating how long the incubation period is, and quarantining the entire region of “furthest possible transmissibility”.

More so, given the overall circular geometry of the world, after a brief period of quadratic growth of the epidemic (as concentric circles expand around the epicenter)  one would expect to see a threshold after which there is merely linear growth in the number of cases as a function of time!

Network Geometry as a Containment Strategy

To a first approximation, the single most important problem to overcome for containment is the exponential growth of the early stages of an outbreak. Of course in some cases an exponential growth is not itself the problem: and R0 = 1.001 leads to exponential growth, but it is still so slow that it can be easily dealt with. Likewise, a sub-exponential growth can still be unruly, as in a polynomial growth with an exponent of 20. But to a first approximation, I would argue that if you can get rid of exponential growth you can manage an outbreak. The example above of a Ringworld shows that exponential growth in contact networks can be slowed all the way down to linear growth at relatively early stages. Similarly, “thin” toroidal planets would also enable easy containment of outbreaks (Anders Sandberg‘s amazing work on the physics of toroidal planets finally pays off! It remains to be seen when his work on stacking high-dimensional polytopes finds real-world applications).

torusdonut2-thumb (1)

Toroidal World

But we don’t have to go all the way to high sci-fi scenarios to encounter sub-exponential growth of infections in human contact networks. You see, the black death happened at a time when the contact network of humanity had a quasi-quadratic structure at the largest of scales. Villages almost certainly had a scale-free structure (e.g. the priest touching everyone once a week and the lone serf perhaps only interacting with two people a week), but once you look at the structure at scales above the village, you would find routes between neighboring villages weaving a planar graph with a 2D Euclidean geometry. The trade routes, though, provided an exception, and in the end they turned out to be key for the spread of the plague. That said, in the absence of cars, trains, or airplanes, the maximum speed of transmission was seriously limited. Historians can tell when different parts of Europe got the plague because it really took a long time to spread; we are talking about years rather than weeks.1920px-1346-1353_spread_of_the_Black_Death_in_Europe_map.svg

So imagine having a contact network structure characteristic of the medieval times, but with an information network structure akin to the ones we currently have. Then controlling the black plague would be a piece of cake! You would simply need to close central trade routes, track down which villages are already infected, and put a perimeter around them.

Ok, so how do we generalize this idea to the modern times in a realistic way? I think we should perhaps think outside the box here. Remember, the core intention here is to make the spread of an infectious disease not behave in an exponential way at the beginning so that we can “segment out” the part of the network affected (i.e. quarantine) because the “surface area” of the region is not very large. Now, most analysis of disease spread on networks focus on analyzing how realistic-like network features affect disease spread. For example, clustering coefficients, the steepness of the slope of power law networks, the distribution of in-betweenness centrality of the nodes, and so on.

In a perhaps high-modernist style approach to network engineering, one can ask how the spread of a disease would change depending on alterations we could make to the network. The simplest real world case is the reasoning behind adding travel restrictions, which aim to block the spread between very large clusters (i.e. countries) and the closing of schools, universities, and large gatherings, which decrease the interconnectivity of each region of the network. A slightly more sophisticated version of this approach would be to come up with a “Pandemic Klout Score” for each person based on the their “network influence” and pay them to quarantine early on during an outbreak.

I actually worked at Klout as an intern in 2010, and my contributions were mostly on the (unfortunately slightly evil because it’s marketing) following problem: “How do you maximize the spread of a commercial campaign by giving free products to people?” Klout had what they called “perks” which was how they made money. They had contracts with other companies to give free products to “influencers” so that they talked about the perks on their social media accounts. To maximize the spread of a commercial campaign meant to distribute perks in such a way that the largest number of people made mentions of the campaign on their networks (including people who didn’t receive the free products). This is how they measured success- at least when I was there- and what the companies paid them for.

The “basic approach” would be simply to distribute the perks to people with the highest Klout scores, with the additional constraint that those people were influential on the relevant topic (e.g. if you had a popular Twitter account about “beauty and personal care” you might be a prime candidate to get a free “anti-aging sunscreen stick”, or whatever) . But since you can’t actually, you know, entice Justin Bieber (the person with the highest Klout score for several years) with a free Virgin America flight and expect him to either care or talk about it on his Twitter feed, the problem ends up being substantially more complex than just “give people with high Klout the free products”. I am under an NDA about the specific algorithms and research I conducted there. But I mention this because the problem of pandemic prevention could in some sense be thought of as the inverse of the problem Klout was trying to solve. Namely, how you use the node features of the network in order to minimize the spread of a contagious disease. The low-hanging fruit idea here can be to simply allot money to pay people with high Pandemic Klout Scores to stay home or cut their human touch in half whenever an outbreak arises. I would expect this to be significantly better at reducing the reproductive rate of a contagious disease than choosing people at random (or even just based on how many people they interact with on a daily basis).

That said, given the risks and costs involved with pandemics, especially in the long term in light of bioterrorism, we should not close off the possibility of making drastic changes to humanity’s contact network for the sake of our collective wellbeing. That is, merely asking some people to stay home may not be enough. We should contemplate what it would really take to be able to fully contain any future pandemic.

In terms of large-scale network geometry rather than just dealing with one node at a time, perhaps the key point to make is that we should really not fetishize and romanticize the “six degrees of separation” that results from the small world-like structure of the modern human contact network. Yes, “it’s a small world after all“, but you forgot to mention “and that’s what will get us all killed in the end.” Let’s not allow misguided network idealism to murder grandma. We need to make the contact network a large world, and save the small world exclusively for the information network.Screen-Shot-2012-04-05-at-19.26.38

Intuitively, it is precisely the small world-like property of our contact network that allows us to: meet many new people on a regular basis, collaborate with people around the world, be able to attend large gatherings, raves, and festivals, and travel care-free across the planet. Meaning, most people might think that changing the contact network structure to make it pandemic-proof would come at the cost of sacrificing what makes society so interesting and worth living in. I would disagree. I think that such a line of thinking is just the result of a failure of the imagination. We can, I posit, have contact networks that allow you to do all of that and yet be pandemic-proof. I will argue that with intelligent top-down network engineering you can in fact achieve this. Here is my case:

Scale-Dependent Geometry

The main concept that one needs to understand for my argument is that the options for large-scale network structure go far beyond the textbook examples of small worlds, scale-free, random, planar graphs, etc. In fact, one can create all kinds of fascinating hybrid networks where the properties vary by region and scale. The examples I am about to show you play with the notion of scale-dependent geometry. Meaning that the network properties depend on the number of interconnected nodes that you are considering. In particular, I’ll break down networks in terms of their micro (1 to 1,000 nodes), meso (1,000 to 1,000,000 nodes), and macro (1,000,000 to 1,000,000,000 or more nodes) structure:

QLE_ELQ

QLE and ELQ

QLE

The first example is one where the structure of the network leads to quadratic spread on the micro level, linear spread on the meso level, and exponential spread on the macro level. We achieve this by having the nodes arranged along a rectangular grid at the micro level. As one zooms out, the grid hits a limit on two fronts so that the advancement of an infection disease will start growing linearly as it only has two directions to grow in (for the sake of symmetry you can glue the two fronts to make a tube, for a meso network structure akin to that of a toroidal planet). Finally, at the largest scale this network looks like a binary tree, where the growth can reach an exponential rate.

The same scheme will apply to all of the following networks. That is, the letters indicate the ordering of the types of growth for the micro, meso, and macro scale. What I will instead focus on is explaining the advantages of these structures. In this case- the case of QLE- the primary advantage is that the spread can be entirely contained by cutting connections around the epicenter. And the best part is that even if you hit the exponential scale (i.e. you start spreading from “one arm to another”) you will still have long periods of linear growth as each “arm” will grow linearly, so cutting it will remain an option at any point. The “surface area of the spread” will remain tiny relative to the size of the network.

ELQ

A very nice property of this network is that you can have “villages” of up to 1,000 people where everyone can interact with and touch each other. Within each of these villages you have super efficient in-person information transmission and contact hedonism without restrictions. Then each of these villages would be connected to two neighboring villages, perhaps not unlike how kids in grade school often make friends with other kids in the grades immediately above and below (and only rarely with grades that are further apart). The spread of disease would very quickly engulf each village, but thankfully that would be it. After that you would have a very slow village-by-village take-over that could be stopped by ‘cutting’ the contact channels between two pairs of villages (or four if you started at an intersection of the macro structural grid). More so, you could conceive of a “conveyor belt” approach where every month half of the village moves in one direction while the other one stays put. This way over the course of years you would still be able to get to know tens of thousands of people, party like crazy in raves touching everybody, and be able to retain long-term friendships by coordinating with them to either move or stay. And you could do all of this while living in a pandemic-proof world!

LQE_EQL

LQE

This one is perhaps the least viable because it relies on most persons only having contact with two people. That said, the spread would start very, very slowly, and so it might be ideal for the worst possible pandemics. At the macro level the network looks like high-dimensional cardboard boxes, where each “cardboard side” is glued at the edge with one or multiple other sides.

A “continuous” version of LQE could use hyperbolic geometry at the macro level, such as what you get when you sneak a pentagon here and there in an otherwise rectangular grid so that locally you have a square spread, which slowly turns into an exponential spread as you begin swallowing pentagons. (Or a few heptagons in a grid of hexagons).

EQL

This one is pretty similar to ELQ, and you can do pretty much the same things I mentioned about ELQ. The main difference is that this structure is safer at the macro level but riskier at the meso level. So if you expect diseases to be really really contagious, then this structure might prevent “the end of the world” but it might be somewhat susceptible to “pretty bad scenarios”, while ELQ works the other way around.

LEQ_QEL

LEQ

I find this network very interesting because to build it I had to come up with the idea of connecting lots of cycles of different lengths with each other by having them share nodes. You can also easily construct a network like this by starting with a scale-free network and replacing the edges with long chains of nodes.

QEL

This would perhaps be the steel-manned version of the toroidal or ring world we discussed in the introduction. Here the infections would spread first slowly at a quadratic rate, then quickly accelerate once you reach the edges of the planar graph you start in, and finally there is a massive linear bottleneck at the macro scale. It’s like Ringworld, but where you interact with people in an interlaced braided mesh embedded inside the Ringworld rather than only in its meager inner surface.

Because each of these examples contain a “linear bottleneck” at some scale, an outbreak of a disease would be easy to contain at some scale. Which network is ideal for which kind of disease will depend on things like its incubation period and its contagion probability. But any of these examples is vastly safer pandemic-wise than our current contact network.

Is Biology Doing This Already?

One thing this exercise has made me wonder is if perhaps our bodies are already using this kind of strategy. I mean, looking at QLE reminds me of the structure of blood vessels in the kidney and liver. It would make sense that evolution would identify great micro, meso, and macro network structures in order to give each organ appropriate contact networks at the scale that matters to conduct its function, while creating network bottlenecks at other scales for protection against pathogens and the spread of cancer. In contrast, the immune system would have every reason to maximize spread at the largest scale while having compartmentalized spread at the micro scale (example: Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality). Finding the sub-exponential chokepoints in the human body would, I posit, give us a new angle for understanding it more deeply.

Creating a Global Human Organism

If this analysis pans out, we could perhaps think of the challenge being presented to us by SARS-CoV-2 and future pandemics as a wake up call to “scale up the network-protective measures our bodies are taking to combat disease while maintaining functionality” all the way up to the structure of all of human society. Indeed, wouldn’t it be amazing if we coordinated to be a harmonious large-scale global organism?

Now, I am not saying we should simply adopt one of these network structures. They are just proofs of concept to show it is possible to have humanly-desirable properties that come with highly interconnected networks along with a linear (or at least sub-exponential) bottleneck at some scale. The bottleneck does not even need to be visible or detectable from the point of view of each individual!

Even if we cannot construct an ideal world from scratch, we could still try to bootstrap it from within our current world. To do so we have a number of options. I will mention two and then dive into them in greater depth. The first is the strategy of “network modification” and it consists of developing gradient descent algorithms that point us to the modification of the network that would maximize a scale-specific sub-exponential bottleneck. Of course this could lead to local minima, but we don’t care about achieving the best configuration, just the closest one that is “good enough”. The second approach is that of “network nucleation” to bootstrap a pandemic-protected contact network by connecting with other people who can prove that they do not have the disease. They could all get to know each other, and then submit a list of “people they would like to hang out with on a regular basis”. An algorithm would then optimize the network so that each person can hang out with as many others as possible while making sure the overall geometry of the network is desirable for disease contention. If lucky, we could even bootstrap this system all the way up to the entire planet, starting from a mixture of people who’ve demonstrably been quarantined for a long time and people who have already recovered from the disease. And since, of course, people would eventually get sick of hanging out with a restricted list of friends, they could periodically re-submit another list and the algorithm would take into account this dynamic so that the geometry can be stable over time.

My prediction is that the current strategies that are being used to reduce the spread of disease would show up as a tiny subset of the set of possible effective strategies, many of which are currently invisible- and in some sense inconceivable- to us. This is because, in part (as far as I know) nobody is thinking in terms of scale-specific network geometry. Also, little is known about the actual empirical structure of the human contact network. In this sense, removing super-spreaders or closing schools may be re-conceptualized as pointing in this direction, and yet perhaps may not even make the Top 10 list of best cost-effective strategies. This is because just removing high-degree nodes in a scale-free network won’t automatically prevent exponential growth; since exponential growth is the killer, making strategies directly targeted at it will probably be vastly more effective. Let’s investigate these strategies in more detail:

Option 1: Network Modifications

The first thing we should do is find what actual contact networks look like, so that we can identify the smallest possible modifications to them in order to create sub-exponential bottlenecks on some scale. I have not found a good study on this, since there really aren’t public datasets of “who is physically hanging out with whom”. Though, if you were to combine, perhaps, the datasets of USA’s NSA, UK’s GCHQ, Russia’s KGB, China’s MSS, cellphone location information, census responses, and commercial surveillance camera data you might be able to get a very decent version of it. In fact, there is reason to believe Israel is already in the process of constructing this dataset.

In the absence of contact network data, we can nonetheless learn from other social and information networks. In particular, the best research I’ve read about the macro-structure of complex networks comes from the lab of Jure Leskovec (I recommend watching his CS224W lectures from past years, which are all available online):

We study over 100 large real-world social and information networks. Our results suggest a significantly more refined picture of community structure in large networks than has been appreciated previously. In particular, we observe tight communities that are barely connected to the rest of the network at very small size scales; and communities of larger size scales gradually “blend into” the expander-like core of the network and thus become less “community-like.” This behavior is not explained, even at a qualitative level, by any of the commonly-used network generation models.

Lescovec et al. 2008, “Community Structure in Large Networks: Natural Cluster Sizes and the Absence of Large Well-Defined Clusters

As you see, large-scale analysis of real-world networks indicate that they are not adequately described by the classic textbook structures that are most well known. Rather, there seems to be a kind of “galactic shape” at the more macro scale, where there is a highly connected giant core of overlapping communities surrounded by loosely connected superstructures (nicknamed ‘whiskers’):

Given this structure (and assuming it generalizes to contact networks), one could divide the problem into two rough components: (1) how to you deal with ‘whiskers’?, and (2) what do you do about the ‘galactic core’? I do not have answers here, but I do think that having more people who are good at math and computer science think about this would be very good. For what is worth, I have the hunch that in particular the following two network analysis techniques will be useful to tackle this problem:

  1. Spectral Graph Theory: This is a set of techniques that can help us ‘see diffusion bottlenecks in graphs’ at a glance. For instance, these techniques reveal the presence of network “chokepoints” that create insulation in heat flow. Clearly heat flow does not behave in the same way as the spread of disease, but the similarity makes it worth highlighting.
  2. Discrete Differential Geometry: An emerging field that blends differential geometry with network analysis and has shown amazing applications for graphics which can help us ‘see the curvature and dimensionality of a network around each of its nodes’ at a glance. Note: As much as I love hyperbolic spaces, I must admit that from the point of view of early pandemic prevention living in a contact network with hyperbolic geometry is a terrible idea.

Flatten the Network!

One additional interesting approach for Option 1 would be to apply topological clustering techniques to the contact network so that we can identify the hubs with the least desirable network geometry and try to “flatten them”. And policy-wise, I might imagine that in the long-run we could improve the flattening of the contact network by encouraging people to use things like the Bumble app for dating, where you find people physically near you with whom you could form a healthy relationship.

Option 2: Network Nucleation

Green and Red Countries

Countries_Recognizing(Green)_Not_recognizing(Red)_Kosovo

Imagine green are virus free, red are virus uncontrolled, and grey have unreliable statistics. (This actual map is about something unrelated I’m not going to name; it is just used as an example of what the world might look like).

Joscha Bach predicts that in a couple months there will be “green and red” countries, meaning that the outbreak will be completely under control in some countries, and completely out of control in others. I’d also add “grey” to refer to “unreliable statistics”, as many countries might just choose to not monitor the situation. You can imagine what the travel restrictions may be between green, red, and grey countries, as green countries would not find it worthwhile (or at least not politically viable) to accept the risk of reigniting the spread. Grey countries may end up also avoiding red countries while not being allowed to enter green countries.

Speculatively, this would perhaps lead to a worldwide Sakoku phenomenon, but where rather than just Japan, we would have all of the countries of each color becoming economic and cultural blocks.

What I’ll describe below is a kind of generalization of this possibility. Namely, that the blocks don’t need to be country-based.

A very interesting question to ask is “what possible partitions of humanity could create sets of people for whom a green/red/grey dynamic would successfully create clusters of wholly virus-free people?” The existence of at least some greens opens up the possibility of:

Reversing The Pandemic

I address you tonight, not as the president of the United States, not as the leader of a country, but as a citizen of humanity. We are faced with the very gravest of challenges. The Bible calls this day Armageddon. The end of all things. And yes, for the first time in the history of the planet, a species has the technology to prevent its own extinction. All of you praying with us need to know that everything that can be done to prevent this disaster is being called into service. The human thirst for excellence, knowledge, every step up the ladder of science, every adventurous reach into space, all of our combined technologies and imaginations, even the wars that we’ve fought, have provided us the tools to wage this terrible battle. Through all the chaos that is our history, through all of the wrongs and the discord, through all of the pain and suffering, through all of our times, there is one thing that has nourished our souls and elevated our species above its origins, and that is our courage. Dreams of an entire planet are focused tonight on those 14 brave souls traveling into the heavens. May we all citizens of the world over see these events through, Godspeed, and good luck to you.

– Armageddon (1998 film, when the president of the US announces the plans to avert an asteroid that would destroy the earth) [See also: what if they don’t come back?]

Nucleating Whole Virus-Free Communities

The simplest way to create a virus-free community would be to think of verifiable self- quarantining as an investment. If you can prove you’ve been physically disconnected from everyone for 30 days, you would be let into a club for people near you who have done the same already. This could become a large set of people, especially if it turns out that cash handouts are insufficient for millions of people who might end up needing to work in a month or two and defy any kind of large-scale quarantine. Those who can afford (and prove!) that they’ve been diligently quarantining would be allowed in. For a stricter “inner set” there might be stricter criteria where you would need to submit an unfakeable biosample to prove you are not infected (which would be tricky but not impossible given pre-existing DNA databases like 23andMe). Then the algorithm would group you with a subset that you can realistically physically meet, and then allow you to make friends with them. Finally, as you submit a list of people you do want to hang out with long-term, the algorithm would run an optimization process to make as many of the people happy and return the curated list of people you could hang out with so that the network as a whole has convenient scale-dependent sub-exponential chokepoints. I know this sounds like a lot. And it is. But again, pandemics can be really bad. And we have the technology, so why not try?

In a way this idea is the complementary problem to “keeping the virus out of the general population”. In the latter you start out in a fully virus-free situation and try to keep it that way, while the former starts out in a highly contaminated population and tries to “spread health” from the standpoint of a verifiably healthy core. That is, how you create pockets of health in a virus-saturated general population and grow them as much as possible.

Another approach in this vein I can think of is to seed a location with an excess of people who already have immunity and cannot transmit. The people there who haven’t gotten the disease would in a sense be lucky to find themselves around people who won’t transmit it, and thus be blessed with spontaneous herd immunity. That said, the key sacrifice here would be the potential damage elsewhere, where herd immunity would be reached later due to the removed group of immune people. This and the previous approach incur the cost of having to associate with new people, and the relocation challenges would be a logistical nightmare. But perhaps worth doing.

Finally, another approach to this problem would be to use an app with a personality test that is hard to fake, so that only healthy people who score in the top 2% of both introversion and conscientiousness could join the club. It would tell you where to go live with other people who meet the same criteria, and to get a comprehensive test of all major transmissible diseases and treat those you have before relocation. Given the temperament selected for, everyone who becomes part of the community would be extremely diligent about not physically meeting people outside the group and follow the contact network prescriptions dictated by the algorithm. If this sounds like hell to you, well, perhaps it is not for you. But at least this way there would be some pockets of fully healthy people, and that would have a lot of value. (Cf. Rat-free Alberta).

To Summarize:

What are your options for modifying a network in order to remove (or at least tame) exponential growth? The one’s I’ve considered are:

  1. Remove nodes with a high “Pandemic Klout Score”
  2. Creating sub-exponential chokepoints:
    1. Option 1: Gradient descent methods:
      1. You make piece-meal modifications to the contact network one connection at a time in order to improve the prospects of the entire network.
      2. Each person would receive a set of options for mild modifications to their contacts so that whichever they chose would lead to an improvement of the network geometry.
    2. Option 2: Network nucleation:
      1. You create a criteria for what constitutes “infection-free” such as:
        1. Self-enforced quarantine on one extreme, and
        2. Provable DNA-matched tests on the other extreme.
      2. Allow people who qualify to meet each other.
      3. Everyone submits a list of people they’d like to hang out with.
      4. The algorithm would optimize the connections to make everyone happy and at the same time maximize the sub-exponential chokepoints of the network (such as by making it a planar graph with a high clustering coefficient, etc.).

Now, perhaps if all of this sounds insane and like too much trouble, there is always the option of, er, becoming comfortable with no human touch…

Future Cultures

A Religion of Abstinence of Human Touch

I know how hard it is, what is being demanded of us.

Especially in times of needs such as these, we like to be close to one another.

We understand care and affection in terms of human closeness and human touch. 

But at the moment the exact opposite is the case, and everybody really must understand that.

At the moment, the only real way of showing you care is keeping your distance.

– German Chancellor Angela Merkel, at a Nationwide TV Address (March 18 2020)

Have you ever noticed that it is possible to reproduce without any human touch? Artificial insemination conducted with robotic arms is not a far-fetched prospect. A further question is: can we do away with human touch entirely for all functions of life?

You don’t need to be anywhere to be everywhere.

– John C. Lilly

You may say: wouldn’t a community of touch-free individuals somehow lack the most basic of human qualities, i.e. interpersonal intimacy? I reckon that you would be wrong on more than one account. First of all, insofar as touch-based intimacy is based on endorphin and oxytocin release in conjunction with nervous system entrainment under the hood, there is no reason why one couldn’t engineer a brain-stimulation technology ecosystem so that people receive the same kind of physically, psychologically, and spiritually rewarding feelings of connection by merely acknowledging each other’s presence or synchronizing with each other’s brainwaves. Perhaps even you could achieve this despite doing away with technology, as the power of deep metta meditation would suggest. Perhaps we could all cultivate a loving temperament that embraces all of the universe of sentient beings. Here, the commitment to each other’s physical wellbeing is possible without sacrificing the emotional richness of communion; in principle they could be simultaneously satisfied. Alas, the evolutionary roots of human touch are deep, and trying to mess with them with humans as they currently are is far fetched. But just wait until a virus with 0.98 fatality rate and R0 = 6 is discovered and see what people are willing to do to survive.

This concludes my presentation of the cocktail napkin ideas I’ve considered so far to deal with pandemics. But I still have a couple more things to say about this topic, so I’ll take advantage of the soap box I’m standing on and add:


Now That The World Is Paying Attention

consciousness_of_the_planet

From the 1998 film “Armageddon”

I’d like to draw your attention to the following highly relevant goals that the current crisis highlights:

1) We ought to recognize the existence of extreme suffering so that we focus our efforts on its prevention (asphyxiation is an example of extreme suffering, which is how people are dying of COVID-19).

2) Investigating what makes MDMA and 5-MeO-DMT so special and useful for treating PTSD (as people recover from the disease it will become apparent many experience PTSD associated with the episode – this will need to be addressed on a massive scale).

3) Get factory farms banned (for real, they are the breeding grounds of future pandemics – and they of course also cause the bulk of easily preventable suffering, so there is that too. Every animal product you put on your plate is a probabilistic pandemic on its way. Sorry!).

naval_common_enemy

Let’s make the best of this situation (More Dakka!)


A Few Final Thoughts

The Framing Effect

Recall the “Framing Effect” – the cognitive bias where we prefer an option when the problem is framed in a certain way, and a different option when it’s framed differently even though the corresponding options in each framing are of equal expected value.

I worry a lot of the people in my friend network, and in fact worldwide, might be falling prey to the framing effect for the coronavirus situation:

Here is how the “containment vs. mitigation” problem is being “framed” right now (assume 5 million people will die worldwide if nothing is done, but you can choose to invest your resources on ‘containment’ or ‘mitigation’):

Option A: 10% chance 0 people die (i.e. successful containment), and 90% chance 5 million people die.
Option B: 100% chance 4 million people die.

Clearly option A is more ‘heroic’. Alas, it is the one that leads to more expected deaths.

Now consider the alternate framing that might make you feel differently about the options:

Option A: 10% chance of saving 5 million people (i.e. successful containment) and 90% of saving nobody.
Option B: 100% chance of saving 1 million people (i.e. mitigation prevents many deaths).

In both cases option B is much better by a huge margin. In fact by an expected number of 500,000 people saved. Yet when framed in the first way option A seems a lot more attractive. Why? And should we try to get rid of this bias?

Of course in the real world you don’t have to choose between A and B entirely. You can try to do both containment and mitigation. But you *do* need to choose how to allocate resources, and I believe this framing issue does actually come up in our current situation.

I do want to say that, as Robin Hanson suggests, if we are doing the containment strategy we need buy-in from the population. Some personally costly and dramatic public display of commitment from many people would be useful. I am personally very happy to commit in public to hard-core quarantine if it’s ethically necessary.


Social Withdrawal and Behavioral Enrichment

Social distancing is painful because we are all opioid addicts, namely, addicts to the endogenous opioids released when socializing. With a quarantine in place, we can anticipate that people who are on the threshold of being depressed might cross that threshold as an effect of reduced in-person socializing. Likewise, we can anticipate collective health decline at a statistical level due to reduced exercise, sunlight exposure, and sensory diversity (cf. white torture).*****

Possible solutions? Besides being very bullish on at-home exercise routines and HEPA filters, I would also point out the following. I think that we should not be afraid of comparing ourselves with other animals. Bear with me. Humans, not unlike domestic dogs and cats, benefit from being exposed to a wide variety of novel sensory inputs. If you enjoy scents, for example, it would be advisable to order a set of essential oils or perfume samples in order to trick your brain into thinking you are exploring a larger area than you are. Apparently, for example, big cats in captivity are more engaged and less depressed when you spray Calvin Klein perfumes on their territory. Alternatively, if scent is not something you care about, think of perhaps increasing the repertoire of visual art, dance, food, touch, and music you are exposed to on a daily basis. This, I suggest, will help you keep depression away (for a while longer).

Caption: Just a little bit of behavioral enrichment for you! 🙂

Finally (self-promotion ahead), if you have time on your hands, and you’ve been meaning to dive deeper into Qualia Computing, this might be your chance. I’d suggest you start out with the following three resources:

  1. Top 10 Qualia Computing Articles
  2. Glossary of Qualia Research Institute Terms
  3. Every Qualia Computing Article Ever

And if you are really hard core, feel free to reach out to the Qualia Research Institute to help with volunteer work. Also we are going to be doing virtual internship cycles in April, May, and June, so you can stay home and safe and still collaborate with us. But shh! It’s a secret! (Wait, how come it’s a secret but you now know about it? Well, because you’ve scrolled all the way here, that’s some commitment!).

The End


* A more accurate representation might require the use of directed edges to encode asymmetrical contact relationships. For example: the cleaning crew of a hotel might be more exposed to the guests than the guests are exposed to the crew. Also, when two people who have very different habits of hygiene meet, the cleaner person is more likely to get the short end of the stick transmission-wise.

** It is worth pointing out for information networks the “degree of interaction” between nodes is extremely skewed. You may have a thousand friends on Facebook, but the number of people you are likely to interact on a daily basis will be a tiny subset of them, perhaps on the order of 0 to 20. And among the people you interact with, you are likely interacting much more word-count-wise with some than with the others. Indeed, if you plot the number of words exchanged in private messages between people in an information network, the distribution follows a long-tail.

*** In the long-run, this may also have to apply to information networks. Whether information networks will need also some level of top-down control will be a difficult question to answer that requires a complex cost-benefit analysis beyond the scope of this article. The most important variables being (a) what the benefits of fully-free communication are, and (b) the density and severity of memetic hazards in idea-space, in conjunction with the nature of intellectual selection pressures in future societies. If it turns out that people above a certain level of education and intelligence in a future with far more advanced science and engineering are extremely likely to encounter what Nick Bostrom calls “black balls”, there might be no way around developing tight controls on information networks for the safety of everyone. It this happens, we could also use many of the strategies outlined in this article for contact networks. After all, viruses are related to contact networks in the same way as meme hazards are related to information networks.

**** Of course, in some ways this is more about collective emotional processing than about object-level problem solving.

***** It is worth noting that the better air quality might buffer a bit against these negatives.

One for All and All for One

By David Pearce (response to Quora question: “What does David Pearce think of closed, empty, and open individualism?“)


Vedanta teaches that consciousness is singular, all happenings are played out in one universal consciousness and there is no multiplicity of selves.

 

– Erwin Schrödinger, ‘My View of the World’, 1951

Enlightenment came to me suddenly and unexpectedly one afternoon in March [1939] when I was walking up to the school notice board to see whether my name was on the list for tomorrow’s football game. I was not on the list. And in a blinding flash of inner light I saw the answer to both my problems, the problem of war and the problem of injustice. The answer was amazingly simple. I called it Cosmic Unity. Cosmic Unity said: There is only one of us. We are all the same person. I am you and I am Winston Churchill and Hitler and Gandhi and everybody. There is no problem of injustice because your sufferings are also mine. There will be no problem of war as soon as you understand that in killing me you are only killing yourself.

 

– Freeman Dyson, ‘Disturbing the Universe’, 1979

Common sense assumes “closed” individualism: we are born, live awhile, and then die. Common sense is wrong about most things, and the assumption of enduring metaphysical egos is true to form. Philosophers sometimes speak of the “indiscernibility of identicals”. If a = b, then everything true of a is true of b. This basic principle of logic is trivially true. Our legal system, economy, politics, academic institutions and personal relationships assume it’s false. Violation of elementary logic is a precondition of everyday social life. It’s hard to imagine any human society that wasn’t founded on such a fiction. The myth of enduring metaphysical egos and “closed” individualism also leads to a justice system based on scapegoating. If we were accurately individuated, then such scapegoating would seem absurd.

Among the world’s major belief-systems, Buddhism comes closest to acknowledging “empty” individualism: enduring egos are a myth (cf. “non-self” or Anatta – Wikipedia). But Buddhism isn’t consistent. All our woes are supposedly the product of bad “karma”, the sum of our actions in this and previous states of existence. Karma as understood by Buddhists isn’t the deterministic cause and effect of classical physics, but rather the contribution of bad intent and bad deeds to bad rebirths.

Among secular philosophers, the best-known defender of (what we would now call) empty individualism minus the metaphysical accretions is often reckoned David Hume. Yet Hume was also a “bundle theorist”, sceptical of the diachronic and the synchronic unity of the self. At any given moment, you aren’t a unified subject (“For my part, when I enter most intimately into what I call myself, I always stumble on some particular perception or other, of heat, cold, light or shade, love or hatred, pain or pleasure. I can never catch myself at any time without a perception, and can never observe anything but the perception” (‘On Personal Identity’, A Treatise of Human Nature, 1739)). So strictly, Hume wasn’t even an empty individualist. Contrast Kant’s “transcendental unity of apperception”, aka the unity of the self.

An advocate of common-sense closed individualism might object that critics are abusing language. Thus “Winston Churchill”, say, is just the name given to an extended person born in 1874 who died in 1965. But adhering to this usage would mean abandoning the concept of agency. When you raise your hand, a temporally extended entity born decades ago doesn’t raise its collective hand. Raising your hand is a specific, spatio-temporally located event. In order to make sense of agency, only a “thin” sense of personal identity can work.

According to “open” individualism, there exists only one numerically identical subject who is everyone at all times. Open individualism was christened by philosopher Daniel Kolak, author of I Am You (2004). The roots of open individualism are ancient, stretching back at least to the Upanishads. The older name is monopsychism. I am Jesus, Moses and Einstein, but also Hitler, Stalin and Genghis Khan. And I am also all pigs, dinosaurs and ants: subjects of experience date to the late Pre-Cambrian, if not earlier.

My view?
My ethical sympathies lie with open individualism; but as it stands, I don’t see how a monopsychist theory of identity can be true. Open or closed individualism might (tenuously) be defensible if we were electrons (cfOne-electron universe – Wikipedia). However, sentient beings are qualitatively and numerically different. For example, the half-life of a typical protein in the brain is an estimated 12–14 days. Identity over time is a genetically adaptive fiction for the fleetingly unified subjects of experience generated by the CNS of animals evolved under pressure of natural selection (cfWas Parfit correct we’re not the same person that we were when we were born?). Even memory is a mode of present experience. Both open and closed individualism are false.

By contrast, the fleeting synchronic unity of the self is real, scientifically unexplained (cfthe binding problem) and genetically adaptive. How a pack of supposedly decohered membrane-bound neurons achieves a classically impossible feat of virtual world-making leads us into deep philosophical waters. But whatever the explanation, I think empty individualism is true. Thus I share with my namesakes – the authors of The Hedonistic Imperative (1995) – the view that we ought to abolish the biology of suffering in favour of genetically-programmed gradients of superhuman bliss. Yet my namesakes elsewhere in tenselessly existing space-time (or Hilbert space) physically differ from the multiple David Pearces (DPs) responding to your question. Using numerical superscripts, e.g. DP^564356, DP^54346 (etc), might be less inappropriate than using a single name. But even “DP” here is misleading because such usage suggests an enduring carrier of identity. No such enduring carrier exists, merely modestly dynamically stable patterns of fundamental quantum fields. Primitive primate minds were not designed to “carve Nature at the joints”.

However, just because a theory is true doesn’t mean humans ought to believe in it. What matters are its ethical consequences. Will the world be a better or worse place if most of us are closed, empty or open individualists? Psychologically, empty individualism is probably the least emotionally satisfying account of personal identity – convenient when informing an importunate debt-collection company they are confusing you with someone else, but otherwise a recipe for fecklessness, irresponsibility and overly-demanding feats of altruism. Humans would be more civilised if most people believed in open individualism. The factory-farmed pig destined to be turned into a bacon sandwich is really youthe conventional distinction between selfishness and altruism collapses. Selfish behaviour is actually self-harming. Not just moral decency, but decision-theoretic rationality dictates choosing a veggie burger rather than a meat burger. Contrast the metaphysical closed individualism assumed by, say, the Less Wrong Decision Theory FAQ. And indeed, all first-person facts, not least the distress of a horribly abused pig, are equally real. None are ontologically privileged. More speculatively, if non-materialist physicalism is true, then fields of subjectivity are what the mathematical formalism of quantum field theory describes. The intrinsic nature argument proposes that only experience is physically real. On this story, the mathematical machinery of modern physics is transposed to an idealist ontology. This conjecture is hard to swallow; I’m agnostic.

Bern, 20. 5. 2003 Copyright Peter Mosimann: Kuppel

One for all, all for one” – unofficial motto of Switzerland.

Speculative solutions to the Hard Problem of consciousness aside, the egocentric delusion of Darwinian life is too strong for most people to embrace open individualism with conviction. Closed individualism is massively fitness-enhancing (cfAre you the center of the universe?). Moreover, temperamentally happy people tend to have a strong sense of enduring personal identity and agency; depressives have a weaker sense of personhood. Most of the worthwhile things in this world (as well as its biggest horrors) are accomplished by narcissistic closed individualists with towering egos. Consider the transhumanist agenda. Working on a cure for the terrible disorder we know as aging might in theory be undertaken by empty individualists or open individualists; but in practice, the impetus for defeating death and aging comes from strong-minded and “selfish” closed individualists who don’t want their enduring metaphysical egos to perish. Likewise, the well-being of all sentience in our forward light-cone – the primary focus of most DPs – will probably be delivered by closed individualists. Benevolent egomaniacs will most likely save the world.

One for all, all for one”, as Alexandre Dumas put it in The Three Musketeers?
Maybe one day: full-spectrum superintelligence won’t have a false theory of personal identity. “Unus pro omnibus, omnes pro uno” is the unofficial motto of Switzerland. It deserves to be the ethos of the universe.

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Qualia Productions Presents: When AI Equals Advanced Incompetence

By Maggie and Anders Amelin

Letter I: Introduction

We are Maggie & Anders. A mostly harmless Swedish old-timer couple only now beginning to discover the advanced incompetence that is the proto-science — or “alchemy” — of consciousness research. A few centuries ago a philosopher of chemistry could have claimed with a straight face to be quite certain that a substance with negative mass had to be invoked to explain the phenomenon of combustion. Another could have been equally convinced that the chemistry of life involves a special force of nature absent from all non-living matter. A physicist of today may recognize that the study of consciousness has even less experimental foundation than alchemy did, yet be confident that at least it cannot feel like something to be a black hole. Since, obviously, black holes are simple objects and consciousness is a phenomenon which only emerges from “complexity” as high as that of a human brain.

Is there some ultimate substrate, basic to reality and which has properties intrinsic to itself? If so, is elementary sentience one of those properties? Or is it “turtles all the way down” in a long regress where all of reality can be modeled as patterns within patterns within patterns ending in Turing-style “bits”? Or parsimoniously never ending?

Will it turn out to be patterns all the way down, or sentience all the way up? Should people who believe themselves to perhaps be in an ancestor simulation take for granted that consciousness exists for biologically-based people in base-level reality? David Chalmers does. So at least that must be one assumption it is safe to make, isn’t it? And the one about no sentience existing in a black hole. And the one about phlogiston. And the four chemical elements.

This really is good material for silly comedy or artistic satire. To view a modest attempt by us in that direction, please feel encouraged to enjoy this youtube video we made with QRI in mind:

When ignorance is near complete, it is vital to think outside the proverbial box if progress is to be made. However, spontaneous creative speculation is more context-constrained than it feels like, and it rarely correlates all that beautifully with anything useful. Any science has to work via the baby steps of testable predictions. The integrated information theory (IIT) does just that, and has produced encouraging early results. IIT could turn out to be a good starting point for eventually mapping and modeling all of experiential phenomenology. For a perspective, IIT 3.0 may be comparable to how Einstein’s modeling of the photoelectric effect stands in relation to a full-blown theory of quantum gravity. There is a fair bit of ground to cover. We have not been able to find any group more likely than the QRI to speed up the process whereby humanity eventually manages to cover that ground. That is, if they get a whole lot of help in the form of outreach, fundraising and technological development. Early pioneers have big hurdles to overcome, but the difference they can make for the future is enormous.anders_and_maggie_thermometer

For those who feel inspired, a nice start is to go through all that is on or linked via the QRI website. Indulge in Principia Qualia. If that leaves you confused on a higher level, you are in good company. With us. We are halfway senile and are not information theorists, neuroscientists or physicists. All we have is a nerdy sense of humor and work experience in areas like marketing and planetary geochemistry. One thing we think we can do is help bridge the gap between “experts” and “lay people”. Instead of “explain it like I am five”, we offer the even greater challenge of explaining it like we are Maggie & Anders. Manage that, and you will definitely be wiser afterwards!

– Maggie & Anders


Letter II: State-Space of Matter and State-Space of Consciousness

A core aspect of science is the mapping out of distributions, spectra, and state-spaces of the building blocks of reality. Naturally occurring states of things can be spontaneously discovered. To gain more information about them, one can experimentally alter such states to produce novel ones, and then analyze them in a systematic way.

The full state-space of matter is multidimensional and vast. Zoom in anywhere in it and there will be a number of characteristic physics phenomena appearing there. Within a model of the state-space you can follow independent directions as you move towards regions and points. As an example, you can hold steady at one particular simple chemical configuration. Diamond, say. The stable region of diamond and its emergent properties like high hardness extends certain distances in other parameter directions such as temperature and pressure. The diamond region has neighboring regions with differently structured carbon, such as graphite. Diamond and graphite make for an interesting case since the property of hardness emerges very differently in the two regions. (In the pure carbon state-space the dimensions denoting amounts of all other elements can be said to be there but set to zero). Material properties like hardness can be modeled as static phenomena. According to IIT however, consciousness cannot. It’s still an emergent property of matter though, so just stay in the matter state-space and add a time dimension to it. Then open chains and closed loops of causation emerge as a sort of fundamental level of what matter “does”. Each elementary step of causation may be regarded to produce or intrinsically be some iota of proto-experience. In feedback loops this self-amplifies into states of feeling like something. Many or perhaps most forms of matter can “do” these basic things at various regions of various combinations of parameter settings. Closed causal loops require more delicate fine-tuning in parameter space, so the state-space of nonconscious causation structure is larger than that of conscious structure. The famous “hard problem” has to do with the fact that both an experientially very weak and a very strong state can emerge from the same matter (shown to be the case so far only within brains). A bit like the huge difference in mechanical hardness of diamond and graphite both emerging from the same pure carbon substrate (a word play on “hard” to make it sticky).

By the logic of IIT it should be possible to model (in arbitrarily coarse or fine detail) the state-space of all conscious experience whose substrate is all possible physical states of pure carbon. Or at room temperature in any material. And so on. If future advanced versions of IIT turn out to be a success then we may guess there’ll be a significant overlap to allow for a certain “substrate invariance” for hardware that can support intelligence with human-recognizable consciousness. Outside of that there will be a gargantuan additional novel space to explore. It ought to contain maxima of (intrinsic) attractiveness, none of which need to reside within what a biological nervous system can host. Biological evolution has only been able to search through certain parts of the state-space of matter. One thing it has not worked with on Earth is pure carbon. Diamond tooth enamel or carbon nanotube tendons would be useful but no animal has them. What about conscious states? Has biology come close to hit upon any of the optima in those? If all of human sentience is like planet Earth, and all of Terrestrial biologically-based sentience is like the whole Solar System, that leaves an entire extrasolar galaxy out there to explore. (Boarding call: Space X Flight 42 bound for Nanedi Settlement, Mars. Sentinauts please go to the Neuralink check-in terminal).

Of course we don’t currently know how IIT is going to stand up, but thankfully it does make testable predictions. There is, therefore, a beginning of something to be hoped for with it. In a hopeful scenario IIT turns out to be like special relativity, and what QRI is reaching for is like quantum gravity. It will be a process of taking baby steps, for sure. But each step is likely to bring benefits in many ways.

Is any of this making you curious? Then you may enjoy reading “Principia Qualia” and other QRI articles.

– Maggie & Anders

Harmonic Society (4/4): Art as Valence Modulation and Future Affective Language

The following essay* was recently published in the Berlin-based art magazine Art Against Art (buy issue).

The essay offers eight different models of art: models 1 through 4 have been discussed in academic literature and the current intellectual zeitgeist, while models 5 through 8 are new, original, and the direct result of recent insights about consciousness as uncovered by modern neuroscience, philosophy of mind, and the work of the Qualia Research Institute.

Below you will find models 7 and 8, which conclude this series of posts. (See previous models: 1 & 2, 3 & 4, and 5 & 6).


7. Valence Modulation

What is the difference between indifference and interest, boredom and thrill, despair and bliss? Pleasure! A few grains of this magic ingredient are dearer than a king’s treasure, and we have it a plenty here in Utopia. It pervades into everything we do and everything we experience. We sprinkle it in our tea.

The universe is cold. Fun is the fire that melts the blocks of hardship and creates a bubbling celebration of life.

It is the birth right of every creature, a right no less sacred for having been trampled upon since the beginning of time.
Letter From Utopia by Nick Bostrom

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Photo by Andrés Silva (aka. El Capitán). Claudia Silva (in the picture).

We are now approaching the point at which we will finally start cooking with peanut oil, so to speak. We will finally start thinking about how to build extremely good art from first principles. The ‘Art as Valence Modulation’ model builds on top of the previous model where art involves messing with the brain’s energy parameter. To explain this model we need to introduce two additional concepts:

  1. Neural Annealing, and
  2. The Symmetry Theory of Valence (STV)

Neural annealing is a concept we developed at QRI to extend the entropic disintegration framework.[1] Namely, the most beneficial use of ‘energy’ is to direct it towards the brain’s natural harmonics in order to carve out the presence of a naturally blissful state in everyday life. This process works on a progression that goes like this:

  1. Energy application
  2. Entropic disintegration
  3. Search/self-reorganization
  4. Neural annealing

Together with neural annealing, STV provides an answer for why we experience intensely rewarding states of consciousness from art. Here is where some of the theories that we have been working on come into play. In particular, we hypothesize that when highly-energized states of consciousness follow an adequate cooling schedule, they can give rise to highly ordered states that are experienced as very pleasant and which can carve good attractor states into the brain in the long term. Making an analogy with metallurgy, with annealing, you can increase the regularity of the microscopic structure of metal by heating it above the recrystallization temperature and letting it cool. This results in changed material properties (such as reduced hardness and increased ductility). We hypothesize that something along these lines also takes place in brains. Neural annealing facilitates solving complex constraint satisfaction problems at the perceptual, emotional, and conceptual level. The higher energy enables quick search between possible configurations that satisfy as many constraints as possible (over- stepping the local maxima we are usually stuck within normal energy ranges), while the cooling process solidifies the best constraint satisfaction solutions. Critically, here the STV comes into play by proposing that the more regular the resulting neural structures are, the better they feel. Annealing smooths out inconsistencies and irregularities, which according to the STV are key sources of discomfort. Symmetry, in the form of smoothness and harmony, is why the process of annealing leaves you feeling great.

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Very high-valence annealed states of mind feel cosmic and profound in significance. Images by Adrián Regnier Chávez

In this light, art with lasting desirable mood effects does not only need to increase the energy parameter, but it also needs to know how to lower it at the right schedule in order to leave people annealed to a given desirable mindset. A lot of art that successfully raises the energy parameter nonetheless does not succeed in the ecosystem of human attention, because it does not let people cool off in the right way. More so, an excessively competitive memetic landscape that incentivizes maximum surprise tends to train people to experience too much fear of missing out to let them adequately consume art at the pace needed to leave you better off emotionally. There is genuine wisdom in going to museums with one’s smartphone turned off.

Where do we draw the line between healthy recreation and distraction? Some might say that art in the form of pictures is fine, but audiovisual is too much. Some may be fine with movies but not with VR. Others would be ok with videogames but perhaps not with drugs. Others perhaps would be ok with drugs but not with genetic modification of neuronal gene expression. Some would be ok with that but not with neural dust rewiring, and so on. The format, we would argue, is not what matters. But rather, what the annealing pattern is, which is actually what makes the effects of art stick in the long run (or not).

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Image by Joseph Matthias Young. It makes me think of the aesthetic of the meta-aesthetic.

This way of seeing art is highly generative. It gives us a research lead for how to construct new grandiose and highly-effective art. More so, the model can itself be developed as an aesthetic of its own. Perhaps we could call it the aesthetic of the meta-aesthetic. That is, an aesthetic that rewards distilling the essential reason why any aesthetic can feel good and meaningful. In the future, we might expect to see in stores “Hedonium Magazine” – which catalogues all of the peak-valence states that can be achieved with any method whatsoever, and sees the craft of perfecting neural annealing as itself the highest form of art. Here we transcend the post-modern ethos of giving each aesthetic its place in the garden of paradoxes. Yes, give each aesthetic its place, but do not let that prevent you from building a meta- narrative that ties together and clarifies the value-add of each aesthetic. No aesthetic is above being examined in terms of how it achieves neural annealing in those who consume it.

In turn, this model gives us a new understanding of what an “aesthetic” even is. According to it, an aesthetic is a system for long-term neural annealing. A one-off weird art piece might give rise to annealing and solidify random structures in your brain. An aesthetic is more than that. It is a collection of generator seeds for art pieces that give rise to a coherent form of neural annealing that is reinforced with each piece, no matter how different they may seem from one another on the surface.

A further property of neural annealing is that it is what enables you to fully experience a self-consistent worldview as if true. This bridges the gap between meaning and pleasure, and is at the core of the connection between valence and the experience of sacredness we discussed in model 4. According to model 7, sacred experiences are the result of driving the energy parameter of the brain above the recrystallization threshold and then having it cool down as it reorganizes the elements of a given target ontology and worldview. The result is an annealed mental state optimized to represent that worldview. The sense of global consistency makes the worldview feel good and true, almost as if you were able to smell truth with it. This model would say, thus, that the core mechanism behind every kind of sacred experience is the same. Which emotions, ontologies, and worldviews get annealed is what is different depending on set, setting, and aesthetic (i.e. how the energy sources and sinks were modified). But deep down, it is successful annealing that makes sacred experiences feel so compelling and good.

8. Affective Language: Harmonic Society

An idealised full-spectrum superintelligence will indeed be capable of an impartial “view from nowhere” or God’s-eye-view of the multiverse, a mathematically complete Theory Of Everything – as does modern theoretical physics, in aspiration if not achievement. But in virtue of its God’s-eye-view, full-spectrum superintelligence must also be hypersocial and supersentient: able to understand all possible first-person perspectives, the state-space of all possible minds in other Hubble volumes, other branches of the universal wavefunction (UWF) – and in other solar systems and galaxies if such beings exist within our cosmological horizon. Idealized at least, full-spectrum superintelligence will be able to understand and weigh the significance of all possible modes of experience irrespective of whether they have hitherto been recruited for information-signalling purposes.
David Pearce, in The Biointelligence Explosion (2012)

If we succeed at developing a science of art built on top of a modern science of consciousness, what should we do with it? What would the art of a wise post-scarcity and post-suffering society look like? As far I can tell, Utopia consists of both having the system in place to keep the lights on, while being able to use the surplus energy to power blissful experiences beyond the bounds of our current conceptions.

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Harmonic Society by ALGE

The vision of Harmonic Society is that of a particular type of post-suffering utopia that resolves to optimize for good art. Referencing the models of art we’ve built upon so far: Harmonic Society (1) knows there are stakes in art and hence sidesteps the traps of semantic deflation, (2) avoids runaway signaling and Cool Kid gridlock, (3) utilizes Hipsters to explore promising new frontiers, (4) has mastery over a diverse range of conceptions of the sacred, (5) systematically explores the state-space of consciousness, (6) has a scientific and precise understanding of the energy parameter of experience, and (7) has deep knowledge of how to induce arbitrary types of neural annealing. In addition to all of this, Harmonic Society has (8) a map of all high-level aesthetics, knows what they are useful for, and can instantiate them at will.

In Harmonic Society there is always a way to smoothly transition between seemingly irreconcilable aesthetics. It deeply understands the pros and cons of different aesthetics and knows how to apply them optimally both for instrumental purposes and hedonic value.

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Image by Michael Aaron Coleman

Nowadays a lot of people who could benefit from, e.g. going to art festivals, taking acid, subpack cuddle parties, participating in plays (i.e. exposing themselves to high-end aesthetic experiences), find it hard to do so, because it is difficult to get back to work once the weekend is over after experiencing incredible bliss. A rough solution to avoid residual incompatibility between the state you annealed over on the weekend with the mindset you need today for work would be to develop a mood organ[2] that instantly puts you into any mindset you want. But perhaps a more elegant solution is to have such an advanced and detailed map of the state-space of mindsets that smooth, painless, and synergistic transitory states between arbitrary modes of being are discovered.

Thus, one could one minute be on a 5-MeO-DMT-type white light conscious void ultra-blissful state, the next minute be on a perfectly functional MDMA-like state useful for socializing, the minute after moving to a highly-focused nootropic-like systematizing state, and so on. The aesthetic to foster here is a meta-aesthetic of avoiding sharp discontinuities between mindsets, and allowing you to transition between all known awesome aesthetics. In Harmonic Society the entire state-space of consciousness is your oyster.

A further thought about Harmonic Society is that a sufficiently advanced understanding of aesthetic experience might even revolutionize our understanding of identity.
For instance, a non-trivial sense of personal diachronic identity could arise if everyone
starts to identify with e.g. a different person-specific song. If we truly understood how
valence works and we had full access to our neurocircuitry, we could in a way embody a
given work of art and interact with others in a way that is consistent with the artistic
degrees of freedom our identity allows. This way, people’s interactions could perhaps be guaranteed to be positive. The combinatorial space of possible back-and-forth interactions does not need to be small, since high-energy allows for incredibly varied states. But nonetheless we could get to a point of understanding how valence works such that we could provably demonstrate that two persons with the right neural implementations will always have positive-sum interactions no matter what.

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Identity in Harmonic Society: The aesthetic of understanding the valence of every possible state of consciousness and how to translate what matters between them. (Picture: Symbol of Open, Empty, Closed Individualism from Burning Man Theme-Camps of the Year 2029, Continuity Camp)

Conclusion

As the guiding premise of this essay we started out assuming that there are real and substantial stakes in art. It sure is all fun and games to think that anything goes in art until your landscape of cultural meaning is polluted with replicator strategies and attention-zapping exploits that lead to long-term neuropsychological problems and anneal false and neurotic metaphysics. Understanding art matters.

I would make the claim that a new science of valence, i.e. a new science of pleasure, pain, love, hate, and indeed transcendent bliss, can be a new rallying flag for cultural value. Rather than the messy consilience patchwork between different aesthetics we have today, we might in the future indeed find a true and real grounding for the meaning of beauty and bliss. Contrary to the conservative spirit often associated with calls to reinvigorate an objective sense of beauty, here we arrive at a theory of art that would very well appreciate experiences as outlandish as DMT breakthroughs. This theory of art appreciates such states not “just as much” as fine art, but indeed as far more valuable and implicated in what matters than most of everyday life. For art, meditation, psychedelics, and philosophy all share the fact that they are messing with the energy parameter of experience in powerful ways that can be used to achieve much better and globally-consistent brain states. Understanding that the effects of art can be very strong and life-changing is one thing, but knowing the mechanism of action behind those changes comes with entirely new possibilities and responsibilities. We invite you to consider what this entails, and to join us in envisioning a future Harmonic Society constructed with full knowledge of neural annealing.


[1] It is worth mentioning that Steven Lehar used annealing to describe the subjective progression of his ketamine experiences in his book The Grand Illusion: A Psychonautical Odyssey Into the Depths of Human Experience. [October 2019 – Edit: Carhart-Harris and Friston wrote a paper together in which they discussed annealing in the context of psychedelic research (see summary). The paper was published in July, two months after I submitted this essay to Art Against Art in May of 2019. We are delighted to see independent convergence on this concept and its importance.]

[2] The Penfield Mood Organ is a technology described in Do Androids Dream of Electric Sheep? by Philip K. Dick that allows the user to instantly tune into any of hundreds of possible moods via direct cerebral stimulation. Some example moods include “3. The desire to dial other moods”, “481. Awareness of the manifold possibilities open to me in the future”, “594. Pleased acknowledgment of husband’s superior wisdom in all matters”, and “888. The desire to watch TV, no matter what’s on it”.



Glossary

Cool Kids: Someone who is well-rounded and uses strategic mediocrity in order to entice people to show their peacock feathers. At its extreme, Cool Kids become the leaders of artistic gangs who corner the marketplace of aesthetic attention.

Hipster: Someone who enjoys art and media that seems too obscure to care about. Typically, the preferred aesthetics of a Hipster are highly detailed and focus on specific favored attributes at the expense of well-roundedness. A Hipster does not only have opinions about what is enjoyable, but also about how to enjoy it and why.

Nerd: Someone who wants to figure out what is true, especially as it applies to technical and formal systems. A philosophy nerd, for instance, compulsively tries to figure out ultimate truth.

Minimax art strategies: A strategy for making art that tries to be the best on a narrow set of attributes while neglecting well-roundedness. This is sometimes adaptive and some- times maladaptive.

L1/L2 normalization: Using mean absolute error (L1) favors minimax strategies vs. using mean squared error (L2) which favors well-rounded strategies.



Special thanks to: Michael Johnson, Romeo Stevens, Liam Brereton, Duncan Wilson, Victor Ochikubo, and David Pearce for their thoughts and feedback.



* The full essay’s title is: Harmonic Society: 8 Models of Art for a Scientific Paradigm of Aesthetic Qualia

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Stanley, J. (n.d.). Philosophy of Language in the Twentieth Century. Retrieved from http://thatmarcusfamily.org/philosophy/Course_Websites/Readings/Stanley%20 -%20Language%20in%2020th%20Century.pdf
Marr, D. (1982). Vision: A computational investigation into the human representation and processing of visual information. San Francisco: W.H. Freeman.
Wittgenstein, L. (1953). Philosophical investigations. Philosophische Untersuchungen. Oxford, England: Macmillan.
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Zizek, S. (2019). on #MeToo movement. How to Watch the News, episode 02. RT. Retrieved from https://www.youtube.com/watch?v=ai_UAPaoEW4
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Lilly, J. C. (1975). Simulations of God : the science of belief. Berkeley, Ca: Ronin. Lilly, J. C. (1974). [Programming and metaprogramming in the human biocomputer.] The human biocomputer. Theory and experiments. (2nd ed.). London: Abacus. Wilber, K. (2007). Integral spirituality : a startling new role for religion in the modern and postmodern world. Boston, Mass.: Integral Books.
Kegan, R. (2001). The evolving self : problem and process in human development. Cambridge Harvard University Press London.
Commons, M. (2008). Introduction to the Model of Hierarchical Complexity and Its Relationship to Postformal Action. World Futures. 64. 305-320. 10.1080/02604020802301105.
Falkenstein, E. (2010). Why Envy Dominates Greed. Retrieved May 16, 2019, from Blogspot.com website: https://falkenblog.blogspot.com/2010/03/why-envy-dominates-greed.html
Moji, K. (1998). The Qualia Manifesto. Retrieved May 16, 2019, from Qualia-manifesto.com website: http://www.qualia-manifesto.com/manifesto.html
Borges, J. L. (1944). The Library of Babel (La Biblioteca de Babel), Buenos Aires: Editorial Sur
SleepyE. (2016). DMT Trip: Jester Entity Occurrence From Viewer. Retrieved from https://www.youtube.com/watch?v=fmVA1755ffM
Gómez Emilsson, A. Burning Man Theme-Camps of the Year 2029: From Replicator to Rainbow God (2/2). (2019, April 9). Retrieved May 16, 2019, from Qualia Computing website: https://qualiacomputing.com/2019/04/08/burning-man-theme-camps- of-the-year-2029-from-replicator-to-rainbow-god-2-2/
Johnson, M. (2018). The Neuroscience of Meditation: Four Models | Opentheory.net. Retrieved May 16, 2019, from website: https://opentheory.net/2018/12/the-neuroscience-of-meditation/
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Carhart-Harris, R. L., Leech, R., Hellyer, P. J., Shanahan, M., Feilding, A., Tagliazucchi, E., … Nutt, D. (2014). The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs. Frontiers in Human Neuroscience, 8. https://doi.org/10.3389/fnhum.2014.00020
Atasoy, S., Roseman, L., Kaelen, M., Kringelbach, M. L., Deco, G., & Carhart-Harris, R. L. (2017). Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-17546-0
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The Psychobiology of Subcultures

Evolutionary qualia suggests our inner world-simulations are not merely painted with different colors, but have different soundtracks, aesthetics, narrative themes, and walk-on character status. Cilantro tasting like soap to ~10% of people is merely the canary in the coal-mine. Our differences in qualia (and consciousness more broadly) probably involve modes of experience you and I don’t even know exist.


Excerpt from Global Brain (2000) by Howard Bloom (Pgs. 143 – 146). [Emphasis mine]

Our brains differ as much as our bodies. Indeed, they may differ more. One part of the brain, the anterior commissure […] varies seven-fold in area between one person and the next. Another part, the massa intermedia […], is not found at all in one in four people. The primary visual cortex can vary three-fold in area. Something called our amygdala (it is responsible for our fears and loves) can vary two-fold in volume – as can something called our hippocampus (involved in memory). Most surprisingly, our cerebral cortex varies in non-learning impaired people nearly two-fold in volume.

 

– Dr. John Robert Skoyles

Thanks to Plato, we have what purport to be records of the conversations of a human Cuisinart of concepts, an eclectic sage whose roughly fifty-year-long intellectual life bracketed the Periclean Golden Age (443-429 B.C.). This all-purpose conceptual chopper and blender was that son of a socially high-placed family, Socrates. Experts and neophytes agree that it’s impossible to tell how many of the words Plato ascribes to this self-appointed gadfly were authentic and how many were simply Plato’s way of getting his own notions into the public eye. But one thing is generally accepted as accurate – the names of the folks from whom Socrates extracted opinions before shredding them with the quiz mastering which now bears his name (Socratic dialogue). The cast of characters palavering with Socrates in Plato’s Dialogs, says learned reasoning, was too well known in Athens for Plato to have fudged.

Just who were the fonts of learned conversation whose wisdom Socrates whipped and whirled? Socrates’ interlocutors were frequently famous thinkers from distant cities, each of which specialized in a different manner of plucking goods from its surroundings and injecting them into the circulatory system through which the trade of the Mediterranean and the Black Sea swirled. Socrates was a student of Anaxagoras, who came from the Ionian city of Clazomenae on the coast of today’s Turkey. He was also a disciple of Archelaus, another Ionian import. The Socratic dialogues Plato “chronicled” included those with Protagoras from the Balkan city of Abdera, Hippias from Peloponnesian Elis, Parmenides from Italy’s Elea, and Gorgias from Sicily’s Leontini. Each visiting intellect had been shaped by contact with a unique group of surrounding tribes, and by the exigencies imposed on city structure, domestic habit, and vested interest by distinctive forms of enterprise. One result: each arrival presented a philosophy which appealed to a very different configuration of the human mind.

To understand how philosophy couples with the mind’s biology, let’s track the complex adaptive system’s best-concealed constituent to its hiding place. The five elements of the complex adaptive system are conformity enforcers, diversity generators, inner-judges, resources shifters, and intergroup tournaments. Inner-judges may be the most unusual of the crew, for they are physiological built-ins which work deep inside the body to transform a bacterium, a lizard, a baboon, a me, or a you into a module of a larger learning machine. The basic rule of learning machines is one we’ve already seen: turn on the juice to components which have a grip on the problem at hand and turn off the power to those components which just can’t seem to understand. Inner-judges help decide whether the components in which they reside will be enriched or will be denied, then they aid in carrying out the sentence. The irony is that these evaluators, prize givers, and executioners are built into their victims biologically. On the microlevel, inner-judges work through “programmed cell death” – apoptosis – a molecular chain reaction deep within the genes which ends in cellular suicide. In higher animals the inner-judges dole out interior punishments which range from overdoses of stress hormones to emotional miseries. Or they grant internal bonuses of zest and confidence to those of us fulfilling our group’s needs.

When we feel like kicking ourselves around the block or curling up and disappearing, our condemnation comes from inner-judges like guilt and shame. What’s a good deal harder to realize is that behind the scenes our inner-judges sicken us and dumb us down quite literally. If they sense we’re a drag on the collective intelligence, inner-judges down shift our immune system and neurochemically cloud our ability to perceive. They induce a narcotic haze by swamping our system with endorphins, the body’s self-produced equivalent of morphine*. And they flood us with glucocorticoids which kill off both brain cells and lymphocytes – critical cells in our fight against disease.

Inner-judges measure our contribution to the social learning machine by two yardsticks: (1) our personal sense of mastery; and (2) the hints we get from those around us telling us whether they want us eagerly or couldn’t care less if we disappeared like a blackhead from the face of decent society.

Mastery is a useful gauge. It measures whether we’re coping with the trials tossed our way, and whether our example can help steer others in their trip through choppy seas. Popularity is an equally practical yardstick. It measures the extent to which we’re feeding others’ physical, organizational, and/or emotional needs.

Nestled deep within our neuroendocrine complex, inner-judges operate on a sliding scale. By adjusting our mix of neurotransmitters like serotonin, dopamine, norepinephrine, and acetylcholine, or the balance between the gloomy right and sunny left side of the brain, they shift us from fear to daring, from misery to happiness, from grouchiness to charm, from timid silence to expansive speech, from deflation to elation, from pain to ecstasy, from confusion to insight, and from listlessness to lust or to the resolute pursuit of goals.

Some of us are born with inner-judges whose verdicts are perpetually harsh. The result is depression, shyness, and heightened susceptibility to pain. Others arrive from the womb with inner-judges preset to treat us generously, endowing us with energy, few inhibitions, a deep sense of security, and little sense of guilt or shame. But most of us are in the middle – our inner-judges sentence us sternly or magnanimously depending on the snugness with which we fit our social network’s needs.

Those born with inner-judges excessively lenient or severe have taught us much about the secrets of mental and emotional diversity. Harvard University researcher Jerome Kagan has probably never heard the term “inner-judges,” yet he may have done more than any other psychologist to uncover their capabilities. To understand what Kagan hath wrought, a background briefing is in order.

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The early-twentieth-century psychoanalytic thinker Carl Jung, says Kagan, originated the concept of introverted and extroverted personalities. Jung also believed that each had a slightly different brain structure. Kagan feels that in his own way, he has proven Jung right. He’s found that 10 to 15 percent of infants are born with a tendency to be fearful and withdrawn, while another 10 to 15 percent are born with a flair for dauntless spontaneity. During the last few decades of the twentieth century, Kagan performed numerous experiments and accumulated large amounts of data demonstrating his concept’s validity.

He refers to facts like these:

  • In studies of Japanese and American newborns, some infants took the removal of the nipple from their mouths calmly, while others went into emotional fits. The babies as yet had had no opportunity to learn these reactions from their parents. The tendencies were those they’d brought with them from the isolation of the uterus. At fourteen months, the babies who’d been easily upset at birth were still so oversensitive that they often broke out crying when the sight of a stranger loomed. On another test, babies who became upset at birth when they were switched suddenly from water to a sugar solution squalled hysterically at the age of one or two when their mothers left the room, but babies who had taken the change in beverage casually did not. In addition, a study of 113 children showed that those who had a hard time handling the unexpected when they were one year old were still shy and withdrawn by the time they reached six.
  • This tendency toward variation in personality was not limited to human beings. According to Kagan, it appeared in dogs, mice, rats, wolves, cats, cows, monkeys, and paradise fish. Some of these animals were fascinated by novelty. Others were terrified by anything the least bit out of place.
  • Fifteen percent of cats steered clear of strangers and even avoided attacking rats. This was remarkably close to the percentage of humans frozen by anxiety attacks.

Kagan traces these differences to genes, which can help set off a lifelong domino effect in the brain. The production of key manufacturing enzyme for the stimulant norepinephrine, says Kagan, is controlled by a single pair of genes, making norepinephrine levels highly heritable. Norepinephrine – which is also a potent stress hormone – shows up very early in the development of the embryo, making the hippocampus oversensitive to the unfamiliar, and hyperactivating the amygdala, which jolts us with the warning signal we call fear. The hippocampus and amygdala – as we’ve seen earlier – are central shapers of the memory bank we call reality. They are also key to the inner-judges’ machinery.

[…]

Later in life the products of a prebirth norepinephrine cascade are timid children, who, in carefully controlled studies, are alert to slight changes in tones or brightness of light that other children miss. In other words, these children literally see and hear their world in ways others would not recognize. According to Kagan, the constitutionally frightened are endowed with a limbic system hair-triggered to curse them with a sense of imminent catastrophe. As a consequence, shy children attempt to escape punishment by hiding from everyday events which threaten to torment them hideously. Uninhibited children, on the opposite end of the scale, have underaroused limbic systems and demand a deluge of entertainment to dodge boredom’s intolerability. Their craving for excitement can sometimes wear their parents to a frazzle.

Kagan’s shy children are condemned to solitude and pain by hanging judges in their own biology. Kagan’s uninhibited kids are gifted with indulgent inner-judges predisposed by the limbic system to offer such unearned rewards as boldness and social dexterity. But most of the animals and humans Kagan has studied avoid these two extremes. Seventy percent remain in the middle, their inner-judges handing out positive and negative verdicts according to the rules of the learning machine.fflkm4309e031


*”Endorphin” is a contraption of the term “endogenous morphine.



See also:

Announcement: QRI Presentations at Harvard and NYU

The Qualia Research Institute is in Boston for the month of September.

Yesterday I gave a presentation about the Logarithmic Scales of Pleasure and Pain at the Harvard Effective Altruism student group (video coming soon! – slides).

I will be giving a presentation about The Hyperbolic Geometry of DMT Experiences at the Harvard Science of Psychedelics Club on September 17, at 8pm (Sever 113). The venue is apparently quite large so we are not going to run out of capacity for this talk. Feel free to amplify this as a Schelling point for smart rational psychonauts to meet one another.

Michael Johnson will also be giving a presentation at the Harvard Science of Psychedelics Club: 21st of September (7PM), at the Fong Auditorium in Boylston Hall.

Finally, I’ll be giving a presentation at Effective Altruism NYC (also about Logarithmic Scales) on September 23rd (7PM), at 334 E 30th St #3. See: facebook event.

Both Harvard talks are free and open to the public. The venues have a large number of seating spots, so all you need to do is show up. For the NYU talk the organizers of the event would like you to get a (free) ticket first in order to RSVP and secure a seat as the venue is not very large.

We will record these talks, share them online, and add them to the list of media appearances.

 


 

If you are in Boston, want to meet up with us, but can’t make it to any of the talks: I will show up to the SSC meetup on the 20th of September wearing a Qualia Research Institute shirt. Feel free to find me and say hi.


Many thanks to: Andrew Zuckerman, Kenneth Shinozuka, Jacob Shwartz-Lucas, and
Anisha Zaveri for organizing these events!