QRI Research Revealed: From Theory to Consciousness Engineering (2026 Fundraiser)

(link)

https://qri.org/donate

The Qualia Research Institute is fundraising $1.5M to carry out its 2026 research program. This is the video of our fundraiser presentation delivered on November 20th 2025 at the 16th floor of San Francisco’s Frontier Tower. We make the case that for cutting-edge consciousness research and suffering reduction initiatives, QRI is a top organization in terms of cost-effectiveness.

In this video, Cube Flipper presents on QRI’s think tank approach to psychedelic research over the past few years, including our work on modeling phenomenology using principles from non-linear optics and the launching of heart.qri.org. Andrés Gómez Emilsson then covers QRI’s current most promising research paradigms, recent empirical findings on characterizing dynamic system changes from pharmacological agents, and the vision for the organization’s strategic plan through 2026.

Endorsements of QRI

Scott Alexander: “I do think QRI is amazing. I’m proud to be here. If you’re going to understand consciousness, you need a very rare combination: being brilliant, erudite, focused — and extremely crazy. QRI sits exactly in that sweet spot. And if anyone is going to do it, they are.”

Shamil Chandaria: “QRI is a creative and first principles consciousness research group. Their original and pioneering approach is opening new territory in the field and is exactly the kind of fresh and insightful research that is needed. I always feel inspired by their ideas and have an intuition it will be these bold ideas that will help to make genuine progress in understanding the nature of consciousness.”

Daniel Ingram: “I flew in basically just to be here. I had this feeling that there was something really important with you all gathering — with this energy — for this incredible work, this foundational, fundamental work that QRI is doing. What absolutely blows my mind is how cleanly mathematics — topology, Fourier transforms, linear algebra, frequencies, phase — maps onto deep meditative and psychedelic experience. I’ve been dreaming of this for decades. To see this actually being done, to see real mathematical formalization applied to consciousness, is a dream come true for me. I really think this is how you reach the mainstream. The mainstream will appreciate this — even if it takes time — and it has to understand this if this work is going to scale. So please support QRI. Please support this work that they are doing.”

Christine Peterson: “It’s been my privilege to watch the Qualia Research Institute from very early on, and I’ve been astounded by the level of creativity in this research program. There is nobody else out there doing this kind of work, and it’s hard to imagine something more important. This is how we are going to learn to quantify consciousness, valence, emotional states — how to eliminate truly intense pain, and how to explore the highest levels of human happiness. What’s extraordinary is that QRI is doing this with a tiny team and an extraordinarily small budget. When you see the quality of this research and hear what the budget is, you honestly wonder how it’s even possible. This organization deserves at least a million dollars a year. They know how to squeeze every penny and generate enormous value. This is the great adventure — and this is the moment to step up.”

Chris Percy: “In the academic world I usually work in, people are lucky to have one or two big ideas a year. Andrés has one or two big ideas every month — and QRI now has an enormous backlog of ideas waiting to be developed.”

Matthew Baggott: “I’ve been interested in and working on psychedelics since the 1980s. When I was an undergrad, I didn’t understand why no one was studying these experiences seriously. What always struck me is that we need people who can do careful self-experimentation, observe very precisely, and then make formal models of what’s going on. That is the way forward. A lot of breakthroughs in science and medicine have come from self-experimentation — it’s overrepresented among Nobel Prize winners. So it’s been an honor and a pleasure to see the work at QRI develop over the months and years. Please give them all the support you can. It’s going to make a difference.”

Balázs Szigeti: “The way I came into psychedelics was through a project called the self-blinding microdose study. It was a citizen-science project, and the results showed that microdosing is not better than placebo. That made me extremely unpopular in psychedelic research. But the moral of the story — and how it relates to QRI — is that the self-blinding microdose study started as this weird, funky citizen-science initiative. It was outside of the system, but it tried to say something about what the system really cares about. And I see QRI as something similar: this weird, eclectic, outside-the-system thing. I’m not sure where it’s going, but it’s going somewhere — and I think it’s going to be awesome. What they are doing is really, really unique, and it is just the way forward for this field.”


What’s happening at QRI: We’re moving our theoretical work (Coupling Kernels, Neural Field Annealing, Valence Structuralism) into practical applications: consciousness engineering, incubating startups, and working on alignment problems. This video shows data-driven empirical validation of the Coupling Kernel paradigm with solid preliminary results. Expect QRI in 2026 to deliver peer reviewed papers validating core research threads and concrete technologies that ease pain, enhance baseline wellbeing, and facilitate access to therapeutic extremes of positive valence. Ideas that were on Qualia Computing back in 2016 are now appearing in philosophy-of-mind journals and making waves. This is just the beginning! 🙂


Video Timestamps:

  • 0:01 – Introduction & Christine Peterson
  • 5:08 – Scott Alexander
  • 6:34 – Matthew Baggott.
  • 8:32 – Cube Flipper
  • 1:08:52 – Daniel Ingram
  • 1:14:09 – Balázs Szigeti
  • 1:16:10 – Chris Percy
  • 1:30:22 – Andrés Gómez Emilsson
  • 3:00:11 – Q&A Session
  • 3:13:29 – Community Introductions

About QRI

QRI is a nonprofit think tank and R&D lab studying consciousness. We run retreats studying high-energy states (https://heart.qri.org) where we rapidly prototype experiments and tools. Our approach incorporates physics, phenomenology, philosophy of mind, and psychophysics.

Careers: https://qri.org/careers

HEART: https://heart.qri.org/get-involved

Oscilleditor: https://qri.org/oscilleditor

ClusterFree (Alfredo Parra) – Advocating for DMT as cluster headache treatment: https://clusterfree.org (see: 12+ Reasons to Donate to ClusterFree)

Computational Functionalism Debate (Chris Percy) – Digital sentience debate quiz: https://cf-debate.com/quiz/

Thank you to Taru Hirvonen, Till Holzapfel, Scry and Symmetric Vision for their work on prototypes of our Tactile Visualizer, and to Emil Hall, Taru Hirvonen, and Symmetric Vision for their development efforts on Oscilleditor.

https://QRI.orgDiscord

Blogs: https://qualiacomputing.com/ | https://smoothbrains.net/

X: @QualiaRI | @algekalipso | @cube_flipper | @qualiacomputer | @chris_percy | @alfredoparrah | @ClusterFree_

Substack: substack.com/@andrsgmezemilsson

12+ Reasons to Donate to ClusterFree

Why cluster headache mitigation should become your #1 effective giving priority this Season: impactful, novel, very alive, and with plausible fast results!

By Andrés Gómez Emilsson, ClusterFree Co-Founder & Member of Advisory Board

TL;DR: To motivate action and feel genuine internal alignment around a decision, sometimes we need to see it from many different angles. Even when a single reason should be enough, we need to motivate our entire internal coalition of subagents! Hence, all of these reasons to support ClusterFree in its mission:

Summary of the 12+ Reasons to Support This Cause

  1. Watch real people rapidly improveVideo testimonials of torture stopping in minutes
  2. Logarithmic scale of impact – Helping someone with this condition is potentially one of the highest-leverage interventions anyone can do as a gift to someone’s life
  3. Insurance against illegible suffering – Building a world that takes invisible pain seriously, including your own in the future! (crossing fingers you never experience such things!)
  4. Proof-of-concept for valence-first cost-effectiveness – This illustrates the corner cases where QALYs/DALYs fail catastrophically
  5. Intellectual coalition – Scott Alexander, Peter Singer, Anders Sandberg, Robin Carhart-Harris, etc. have seen the evidence and are convinced this is real
  6. Schelling point for suffering reduction – Network effects for future high-impact work, attracting genuine talent to focus on deep suffering reduction is its own value proposition
  7. It’s a strike against medical paternalism – Informed consent for known therapies, even when not officially approved, when it comes to extreme suffering, should always be an option on the table
  8. Actually tractable – Success looks like a 3-5 year timeline with a clear theory of change
  9. Speed cashes out in suffering prevented – 70,000 people in extreme agony right now, every day of delay matters greatly
  10. Works as an accelerant for an existing movement – Adding coordination to grassroots momentum that’s already underway (giving the psychedelic renaissance wings!)
  11. Psychospiritual merit (if you believe in “karma”) – Buddhist texts specifically highlight headache relief, “immeasurable merit” in store for you and your loved ones if you decide to help with clean intentions
  12. Bodhisattva vision – Practice looking into darkness without flinching
  13. Bonus – I’ll stop talking about Cluster Headaches in Qualia Computing!: Fund it so I can get back to core QRI research

Introduction: Why Multiple Reasons Actually Matter

In principle, deciding where to donate should be straightforward: calculate expected value, fund the highest-impact opportunity, done. In practice, we’re coalitions of subagents with different reward architectures, time horizons, epistemics, and thresholds for action.

At a neurobiological level, motivation doesn’t work the way we pretend. It’s not about “willpower” or “being convinced by good arguments.” Different brain regions make “bids” to the basal ganglia, using dopamine as the currency. Whichever region makes the highest bid gets to determine the next action. Scott Alexander explains this in Toward A Bayesian Theory Of Willpower (2021). What we call “motivation”, within this framework, is just whichever subsystem’s bid is currently winning. Whether the details are right or not, I think this tracks how I see people behave.

If you want to trigger high-effort action, giving just one reason may not be enough. That only raises one bid. Layer multiple kinds of reasons (emotional, moral, social, self-interest, narrative, identity-based), and you multiply the bidders in your internal parliament. Scott uses stimulants as an example: they “increase dopamine in the frontal cortex… This makes… conscious processes telling you to (e.g.) do your homework… artificially… more convincing… so you do your homework.”

Look, I’m being straightforwardly manipulative here. Giving you twelve reasons instead of one is designed to activate more of your subagents. But it’s prosocially manipulative – to help you integrate a truth you might already intellectually accept but haven’t acted upon yet. The bullet point approach can be misused when it obfuscates (think laundry list of complaints when there’s really just one big issue), so let me be meta-transparent: I genuinely believe ClusterFree is extremely high-impact, and I’m deliberately structuring this to get past your action threshold. If any one or even several of these reasons feel less convincing to you, ignore them. The robust core case stands on its own.

There’s also the threshold problem. In Guyenet On Motivation (2018), Scott discusses how higher dopamine makes the brain more likely to initiate any behavior. When dopamine is low, even strong reasons may not overcome inertia. Increased dopamine “makes the basal ganglia more sensitive to incoming bids, lowering the threshold for activating movements.” Sometimes what’s needed isn’t better arguments but enough energetic activation to allow any reason at all to push action over the threshold. Which is why you should read this while high on LSD and/or Adderall fully rested and energized.

Naturally, this connects to annealing. At QRI, we think of belief updating as requiring an energetic process. It’s not enough to know something matters; you need metabolic resources to actually integrate that knowledge and reconfigure your behavior accordingly. The REBUS (RElaxed Beliefs Under pSychedelics) framework applies here: people intellectually understand that cluster headaches are astronomically bad, that preventing them is extraordinarily high-leverage, and that this is one of the most intense forms of suffering you can and should urgently address. Yet this knowledge may remain compartmentalized and inert, unable to meaningfully shape action, resembling other “ongoing moral catastrophes” by which future generations may judge our society.

What breaks through? Multiple simultaneous channels of evidence that together cross energy thresholds. Emotional resonance. Social proof. Narrative coherence. Personal connection. These aren’t redundant: they join together as a gestalt that pushes forward the energetic budget needed for actual system-wide updating.

So here are the twelve reasons to support ClusterFree. Not because you need all twelve to “get it” intellectually, but because different reasons will activate different coalitions in your brain.

And if you’re not in a position to donate but still want to help – please keep reading. There are many high-impact ways to contribute at the end!


1. You Can Actually See People Rapidly Improving

Most charity is abstract. You send money into a statistical void and trust the meta-analyses.

With ClusterFree, you can watch video testimonials of actual people describing how psilocybin or DMT stopped “the worst pain imaginable” in minutes. The person who was screaming, punching walls, and contemplating suicide is suddenly calm, coherent, and alive again.

Watching someone’s face change like that hits you differently than reading a cost-effectiveness analysis. Your brain gets direct evidence of the state change. You see the suffering stop.

And strategically, patient testimonials are how this actually works. Raw video testimonials of “this stopped my torture” create demand that no institutional gatekeeping can fully suppress. People are already using this in advocacy. We’re just collecting the stories systematically and making them impossible to ignore. One major medical center sees enough of these, runs a supervised protocol, publishes clean results, and every other institution’s liability calculation flips.


2. On the Logarithmic Scale of Helping Another Human, This Is Unfathomably High

Preventing cluster headaches for life is plausibly one of the single largest “good deeds” a human can do for another human being. Yes, this is grandiose. But if something big IS true and you know it, pretending it’s not to avoid looking grandiose is fake humility that damages the cause.

Cluster headaches are called “suicide headaches” because the pain is so extreme that people actively contemplate ending their lives during attacks. Patients report “drilling through my eye socket,” “being stabbed in the brain,” “pain so bad I can’t think, can’t speak, can’t do anything but scream.”

Here’s a rough intuitive sketch of what the logarithmic scale of helping another person might look like (this isn’t rigorous math – it’s an illustration of what’s likely the case, directionally right[1]):

  • 10^0: holding a door open
  • 10^1: gifting a pen
  • 10^2: introducing them to someone useful
  • 10^3: helping them move places
  • 10^4: catching a major work or family mistake before it ruins their week
  • 10^5: teaching them a compounding skill (meditation, programming, emotional regulation)
  • 10^6: funding their higher education, changing their entire socioeconomic trajectory
  • 10^7: helping them escape a pathological family system
  • 10^8: preventing them from falling into a cult, deep addiction, or abusive relationship
  • 10^9: curing a chronic condition like treatment-resistant generalized anxiety disorder (GAD)
  • 10^10: saving their life while preserving psychological integrity
  • 10^11: giving them a permanent upward shift in baseline wellbeing and quality of consciousness, such as advanced contemplative practice can do over the course of decades
  • 10^12: preventing cluster headaches for life

Why 10^12? A single cluster headache attack is plausibly in the 10^9 to 10^11 range of negative valence – orders of magnitude worse than migraine, worse than childbirth, worse than even torture. A typical patient experiences thousands of these across their lifetime. The multiplication is straightforward.

We’ve done empirical work quantifying cluster headache intensity using patient self-reports, cross-condition comparisons, suicide attempt rates, and other methods. Full details in our EA Forum posts (Quantifying the Global Burden of Extreme Pain from Cluster Headaches, Logarithmic Scales of Pleasure and Pain) and our Nature: HSSC paper.

The theory of change for the open letters on ClusterFree is straightforward:

Patient testimonials – Raw evidence that DMT/psilocybin (even at subhallucinogenic doses) works for a large fraction of sufferers, spreading organically through desperate communities. This is already happening underground.

Reputation-Amplified Legitimization – Get enough credible voices (clinicians, researchers, policy experts) publicly acknowledging both the crisis and the evidence. We already have 800+ signatures, many from extremely prestigious people. This shifts what’s discussable. Journalists cover it differently. Clinicians stop whispering with fear of judgment and start preparing, even if quietly at first (I’m already seeing signs of this in some groups).

Clinical cascade – One major medical center runs a supervised protocol, publishes clean results, and every other institution’s liability math inverts. You don’t need consensus. You need one proof point, and the dominoes fall.


3. It’s Insurance Against Your Own Extreme Suffering Being Dismissed

Cluster headaches are invisible. No blood, no broken bones, nothing on medical imaging. Just someone screaming, rocking, punching walls while doctors tell them to “try reducing stress”, “have you considered yoga?”, or “maybe try an Ibuprofen?”.

This is what illegible suffering looks like. People don’t believe you. Institutions can’t help you. You’re trapped in a cage of agony that no one else can see.

Supporting work on illegible suffering means supporting the principle that intense subjective experience matters even when it can’t be measured easily. By supporting ClusterFree, you’re building the world where, if you ever wind up in incomprehensible pain (chronic illness, treatment-resistant conditions, novel syndromes medicine doesn’t understand yet, a hard-to-communicate and hard-to-alleviate pocket of deep biopsychosocial suffering), people will actually take it seriously. Where “I am in agony, and this helps” is treated as highly important data, the existence is safer and more dignified.

Medical, institutional, and social gatekeeping kills people. It traps them in years of unnecessary suffering because the safe and affordable tools that work aren’t “approved” yet. By supporting the patient-driven, evidence-based access to what actually helps, you’re contributing to practical moral betterment and making the world safer for everyone who might need it. Including you.


4. It’s a Proof-of-Concept for Valence-First Cost-Effectiveness

Most effective altruism uses QALYs (Quality-Adjusted Life Years) or DALYs (Disability-Adjusted Life Years) to evaluate interventions. These metrics have a major limitation: they systematically underweight extreme suffering. A QALY-based analysis of cluster headaches captures some utility loss but misses orders of magnitude of suffering because attacks are brief and non-lethal – even though they’re torture-level and recurring. The frequency distribution is also extremely skewed (some sufferers have 10+ attacks daily), which standard health economics frameworks struggle to properly account for.

ClusterFree evaluates interventions based on how bad things actually feel and what their actual prevalence is – not through the lens of reduced life expectancy or economic burden: “How much suffering are we preventing when measured by its actual intensity?”.

We’ve quantified cluster headache intensity and prevalence using patient self-reports, cross-condition comparisons, suicide attempt rates, and other complementary empirical methods. The result is clear: cluster headaches score astronomically high. This is why preventing them matters so much more than conventional metrics would suggest.

If you want a future where we optimize for the real reduction of suffering instead of metrics that structurally and systematically ignore its most intense forms, ClusterFree is the seed. We’re showing how you can make rigorous, evidence-based decisions by taking the actual experience seriously. This serves as a template for charity evaluation and ethical triage (not necessarily to replace current Effective Altruism methods, but to add a _critical_ missing evaluation angle to the ensemble model for how to help most effectively). 


5. You’ll Be in the Company of Intellectual Giants

Scott Alexander supports this. Anders Sandberg supports this. Peter Singer supports this. These are thought leaders with decades of track records in rigorous, scout-mindset thinking about doing good. They don’t endorse lightly. They’ve looked at the testimonials, the statistics and trends, the theory of change, and said: this is real.

If you trust their epistemics even a little, their endorsement is strong Bayesian evidence. These aren’t people chasing trends or optimizing for social approval.

And beyond the rationalist/EA sphere? Robin Carhart-Harris supports this – one of the leading psychedelic neuroscientists in the world. Shamil Chandaria supports this – doing serious work on meditation, predictive processing, and contemplative neuroscience. Christopher H. Gottschalk supports this – a neurologist who actually treats cluster headache patients and knows firsthand how devastating they are.

EA thinkers, psychedelic researchers, clinical neurologists, contemplative scientists – they’re all saying the same thing. That doesn’t happen often.

You get to join this coalition early. While it’s still underrecognized. While it requires actually engaging with the arguments instead of following the consensus. While supporting it means skin in the game.

Supporting ClusterFree now signals good taste (you can spot high-impact opportunities before they’re obvious), high reasoning capacity (you can evaluate complex arguments across disciplines), genuine compassion (you care about actual suffering, not just legible causes), and epistemic independence (you can disagree with the consensus when the evidence demands it).

When this becomes mainstream (and it will), you were there first.


6. It’s Creating a Schelling Point for Serious Suffering-Reduction Work

ClusterFree is reducing the coordination costs and bringing together people who can spot neglected pools of immense value early on.

Researchers who care about phenomenological intensity. Clinicians frustrated with institutional gatekeeping who want evidence-based psychedelic medicine. Policymakers who understand regulatory strategy. Patients with direct experience who want to help others. All working on the same thing with a clear theory of change.

Many causes tend to be either too vague (“reduce suffering”) or too narrow (“fund this one study”). ClusterFree hits the sweet spot – it is specific enough to be actionable, broad enough to matter at scale, and legible enough to attract serious supporters.

The network effects compound. When the next high-leverage suffering reduction project comes along, there’s already a group of competent people who know how to execute. The people showing up now will co-build what comes next. Rather than funding one project, you’re seeding a network that keeps generating high-impact work.


7. It’s a Strike Against Paternalistic Control Over Suffering Relief

Right now, people with cluster headaches are told they cannot officially access psilocybin or DMT – the interventions that consistently, rapidly, and reliably work for a large fraction of sufferers – because the institutions have decided they’re not allowed to make that informed choice. Even when they’re screaming in agony. Even when they’re suicidal. Even when nothing else helps.

Medical paternalism is at its most cruel when patients hear: “We know you’re suffering, but you can’t have the effective, affordable, and safe-to-manage thing that stops your agony, because we haven’t finished the proper studies yet, and/or because of the system’s inertia.” Never mind that converging evidence shows it works. Never mind that patients are already using it skilfully and reporting dramatic relief. Never mind that the risk profile is more than worth it given the suffering prevented.

ClusterFree, with your support, is building the legal, scientific, and social infrastructure to challenge that amoral status quo. We pave the way for informed consent, supervised access, and letting people make rational decisions about their own unbearable pain.

If you value bodily autonomy, participatory medicine, and the right to pursue relief from extreme suffering, this is the fight. And it’s winnable thanks to multiple predictors of success. 


8. This Is Actually Tractable

Most extreme suffering feels impossibly hard to address. Oftentimes, contemplating extreme suffering causes a sense of helplessness. It’s too big, too entrenched, and too complex. You can care deeply and still feel like there is nothing you can meaningfully do about it.

Cluster headaches are different. We have video testimonials. We have 800+ signatures from people with institutional power. We have a clear mechanism – psilocybin/DMT abort attacks rapidly and safely. We have willing clinicians ready to run supervised protocols. We have patient demand already creating the underground adoption.

The main barrier is coordination and legitimacy-building. That’s where ClusterFree steps in: we close the gap between common knowledge and the rollout of systemic solutions. 

And we’re going beyond mere advocacy. Bob Wold of ClusterBusters calls DMT a “breakthrough therapy” for its near-instant pain relief; we’re working to understand why it works, so we can foster next best steps. Our research includes exploring legal, non-hallucinogenic (or only mildly hallucinogenic) alternatives like 5-MeO-DALT, which one patient discovered in Shulgin’s TIHKAL and used to successfully treat 46 cluster headache patients. Developing targeted therapies based on understanding the mechanisms and testing new approaches translates into accessibility and effectiveness.

We (admittedly optimistically) believe this is doable within 3 to 5 years of focused and effective execution: build the coalition, get one major medical center to publish clean results, and watch the common knowledge cascade. Meanwhile, we’re already developing better treatments with maximally broad legal adoption.

Most things that matter this much take decades… or never even happen. This one is actually within reach.


9. Every Month of Delay Means Unnecessary Pits of Suffering

Right now, while you’re reading this, ~70,000 people are experiencing a cluster headache attack. More will start in the next few minutes. And more after that, like a global wave of agonizing pain.

Roughly 3 million people worldwide have cluster headaches in any given year. Many experience attacks daily or multiple times per week during the cluster periods. We estimate that globally, cluster headache patients spend approximately 70,670 person-years per year in pain, with about 8,570 person-years (about 3.1 million person-days) spent at extreme pain levels (≥9/10).

The math is brutal: with every month of delay, patients undergo millions of preventable torture-level attacks. While other cause areas and interventions may warrant dilemmas of donating now or later, the case of ClusterFree is urgently clear – donate now, and we will do our best at bringing unimaginable counterfactual relief to millions in 2026-2027. 

Our model is designed for speed – we are not waiting for perfect RCTs, commercial products, or stable institutional consensus. We are building the strategic legitimacy cascade that lets institutions act on what we already know.

The suffering is happening right now. The effective solution exists right now. We know how to connect the dots, and the only question is how fast we can do so.


10. ClusterFree Is Accelerating an Already Developing Movement

ClusterBusters has been doing heroic work for years, building community, sharing information, and giving people hope. The psychedelic renaissance has been shifting cultural and scientific attitudes. Various researchers and advocates have been pushing this forward through different channels.

ClusterFree adds a specific piece: demonstrating that this is a winnable fight right now.

We bring:

  • An explicit theory of change (testimonials lead to reputation-amplified legitimization, which leads to clinical cascade);
  • 800+ signatures from outstanding individuals, many with institutional power and cultural influence;
  • A straightforward narrative: “this is effective, safe, and urgent, and we can scale this legally” – and we’re not afraid to signal DMT as especially promising (due to its extremely fast pain relief profile when “vaped” at the onset of an attack);
  • Coordination infrastructure that connects patients, clinicians, researchers, and funders around a shared goal; and
  • A global but local-context-sensitive approach in both coverage and mindset: while ClusterBusters focuses on the U.S. and UK, we’re building parallel advocacy tracks across multiple jurisdictions (Canada, Europe, Latin America, etc.) to build the missing capacity.

This strategy acts synergistically with other approaches, de-risking them rather than obstructing them. When a major medical center decides to run a supervised protocol, they will do it in an environment where 800+ credible voices (as of December 13th 2025) have already confirmed that this is real, this matters, and the research must take place as soon as possible.

Our strategy is being developed and executed by uniquely talented individuals with a strong track record. Alfredo Parra leads the organization – he is exceptional at navigating the interface between institutions, has 7+ years of nonprofit management experience, and is provingly extremely conscientious and high-integrity (don’t take my word for it – look at all the work). The team and the community that seeded it concentrate people who simultaneously understand the importance of suffering reduction, psychedelic phenomenology, regulatory strategy, and movement building. They both care about the deep structure of consciousness and aren’t swayed by common narratives. This is a rare comparative advantage, and in our view, proves an excellent fit to push this cause forward.

The fruitful work has been happening already. Where we step in is providing leverage at a specific bottleneck: making the path to legitimacy visible and coordinated.


11. If You Take “Karma” Seriously, Look at What the Texts Say About Headache Relief

In the Bodhicaryāvatāra, Śāntideva teaches that “immeasurable merit” arises even from the simple thought: “Let me dispel the headaches of beings.” The tradition treats this literally. Not metaphorically. Relieving sharp, overwhelming pain generates outsized karmic effects because it interrupts some of the most intense forms of duḥkha in the human realm.

Why headaches specifically? Because they were considered the archetype of piercing, mind-breaking pain in the classical world. Cluster headaches exceed even that ancient benchmark. They represent some of the most unbearable moments a human mind can experience.

The logic of meritorious karmic logic is clear: if intention aligned with the relief of severe suffering produces merit that scales with the intensity of dukkha relieved, then work that prevents torture-level pain for thousands of people is not ordinary charity but a high-density, boutique, ultra-rare karmic investment.

For practitioners of the Bodhisattva path, karma constitutes a feedback loop shaping future clarity, opportunity, and awakening. Helping beings escape states of extreme pain is singled out across the Mahāyāna as one of the fastest ways to accumulate merit and purify obscurations.

If even contemplating the wish to relieve a single headache creates immeasurable merit, then actively supporting work that may end this class of suffering at scale plants karmic seeds that ripple across lifetimes.

Even if you hold a weak, naturalized version of karma (something like “intentions to help tend to produce good outcomes proportional to the good intended”), the efficiency here is absurdly high. Instead of helping someone have a slightly better day, you’re preventing thousands of hours of above-torture-level pain per person.

And what if you don’t believe in karma at all? The consequentialist case is still clear. You’re preventing, say, ~10^12 units of negative valence per person.


12. You Get the Bodhisattva-Tier Vision

Most people, when they look into the true darkness of suffering (the worst pain imaginable, sustained for hours, recurring for decades), recoil. They look away. They rationalize (“someone else will handle it”), they cope (“well, suffering is just part of life”), and freeze (“I can’t do anything about this anyway”).

Such reactions are understandable given the limits of our agency and the scope of the challenge. Luckily, there’s another response possible and available today:

You see it, and you roll up your sleeves. Where others flinch or cope, you take intentional action.

That capacity to clearly perceive the worst of what’s real and respond with competence, care, direction, and focus – rather than despair, avoidance, denial, or freezing – is a rare gem. It separates people who talk about compassion from people who enact it. The “Bodhisattva move” is: “I see the suffering. I will not turn away. I will do what needs to be done.”

Supporting ClusterFree strengthens that moral muscle. It’s a practice for the kind of person you may want to be: someone who can look into the darkest abyss and respond with pragmatism, not platitudes.


And a bonus reason for Qualia Computing readers…

So I Can Stop Talking About Cluster Headaches in Qualia Computing

Look, I very deeply care about this work, and this is why ClusterFree needs to claim its own space. QRI has a complementary mission to fulfill – studying and utilizing coupling kernels, topological approaches to the boundary problem, neural annealing frameworks, and the deep structure of valence.

The more ClusterFree is funded and self-sufficient, the more I can get back to the core theoretical work for which I’m best suited. Which, by the way, is exactly how we identify the next high-leverage suffering reduction opportunities!.

If you want me to shut up about cluster headaches and get back to talking for hours about beam-splitter holography and DMT phenomenology, the fastest way to make that happen is to generously fund ClusterFree.

You’re welcome.


What We’re Specifically Asking For

ClusterFree is currently a two-person operation: Alfredo leading the day-to-day execution (coalition building, clinical coordination, policy navigation, the 800+ signature campaign), and me providing strategic direction, research frameworks, writeups like this one, and QRI infrastructure. The initial donations will let us hire additional top talent to manage critical workstreams, so that we can:

  • Pursue parallel regulatory tracks in different jurisdictions;
  • Optimize our media presence by talking to journalists, podcasters, and medical journals;
  • Build global partnerships with patient organizations, headache centers, psychedelic advocacy groups, and retreat centers that treat this and related conditions;
  • Coordinate with medical centers willing to run supervised trials;
  • Create high-quality topical resources for patients in multiple languages, which are scarce and difficult to find; and
  • Pursue other high-impact value streams we’re ready to launch with additional capacity.

If significant funding is obtained, it will allow us to personally visit retreat centers and bring people with cluster headaches to suitable settings where they can experiment with these therapies, and where we can study them thanks to the QRI approaches to systematic phenomenology mapping, including EEG and biorhythms monitoring. This might turn out to be really important, possibly allowing us to determine what aspect of psilocybin/DMT relieves the pain. Our working assumption, based on many interviews with sufferers, is that DMT’s “body vibration” effect is key for its pain relief – if true, this is something we could significantly optimize by developing more targeted therapies.

While our network of volunteers is growing (see Slack below), having dedicated paid staff accelerates our efforts dramatically. The faster we move, the louder we say “no” to overlooked suffering.


Can’t Donate But Want to Help?

There are many high-impact ways to contribute beyond financial support:

  • Sign the open letter – Adding your name increases our legitimacy and helps shift the Overton window.
  • Share patient testimonials – If you have cluster headaches and have used psychedelics, your story can help build the evidence base. We believe that video testimonials from sufferers, in particular, are especially powerful. Recordings showing the moment itself where psilocybin/DMT relieves the suffering in real time might have the most emotional resonance overall.
  • Join our Slack – We list simple but high-impact volunteer tasks (translations, social media, research assistance, essay feedback, etc).
  • Connect us with key people – Do you know journalists, podcasters, clinicians, policy makers, or potential donors? Introductions are greatly appreciated!
  • Spread the word – Share this essay, talk about cluster headaches with the right mood, and become the relieving change you want to see and experience in the world.

Conclusion

With all these reasons in mind, ClusterFree satisfies the utilitarian, the virtue ethicist, the long-term strategist, the person who wants meaning, the person who values courage, the person who wants to accumulate spiritual merit, the person who wants to bring these therapies to the FDA approval status, the person who just wants to see real humans stop screaming in pain, and the one who embodies all these motivations simultaneously.

Donate to ClusterFree

Donate to QRI (the incubator organization that made this possible, and conducts more aligned efforts)

Sign the open letter

Our internal coalitions can agree that this matters, and we can actually do it. Thank you.


Acknowledgments: Many thanks to Marcin Kowrygo for his generous edits of the draft. Thanks to Chris Percy, Roberto Goizueta, Hunter Meyer, and, of course, Alfredo Parra for relevant discussions and suggestions for this write-up. Huge thanks to the ClustersBusters team for their incredible and ethically urgent work (and generosity with their time to help people in need, as well as accepting being interviewed in a pinch at Psychedelic Science 2025). Thanks to Jonathan Leighton (OPIS) for inspiration, aligned work, and fighting the good fight! Thanks to Jessica Khurana (and her team) for founding Eleusina Retreat – the world’s only retreat center focused on using psychedelics, legally, for treating extreme pain conditions. Thanks to Maggie Wassinge for her copious emotional support, love, and motivation to keep doing the real work, even when it feels hopeless at times (seriously, THANK YOU). And to the spirit of Anders Amelin (RIP), who is always with us, encouraging and motivating, giving us strength and intelligence. May he rest in peace, knowing we’re pursuing our ambitious suffering-reducing goals <3 And thanks to the entire QRI team, as well as the broader qualia community at large, for creating a container where these ideas can be freely explored with curiosity and without stigma. And finally, thanks to all of the donors of QRI and ClusterFree: we will do what we can to make you proud of supporting us. Metta!


[1] On the 10^12 estimate: This is admittedly a back-of-the-envelope calculation, but here’s the reasoning. A cluster headache patient might experience anywhere from 3,000 attacks (conservative, successful treatment) to 30,000+ attacks (severe chronic cases) over their lifetime. Using a conservative estimate of 3,000 attacks averaging ~60 minutes (3,600 seconds) each gives us ~10^7 seconds of extreme pain. Now for the intensity ladder. Holding a door open might prevent ~0.1 units of discomfort, using a pinprick as 1 unit. Kidney stones, already rated 10/10 on standard pain scales, are plausibly ~1,000× more intense than a pinprick (10^3). Each second of cluster headache pain appears to be ~10× worse than kidney stones (10^4 relative to our baseline). Multiply by 10^7 seconds, and we get 10^11 from pure hedonic intensity alone. Additionally, cluster headaches impose a constant inter-ictal burden (meaning, the suffering between attacks), including PTSD, anticipatory anxiety, and a profound sense of doom between attacks (see interview with Cluster Busters founders at 53:10-53:40). This could add a 2-5X multiplier, bringing us to ~10^12. For severe cases with 10× more attacks, the calculation easily reaches 10^13 or higher. The true value likely ranges between 10^7 (very mild cases with effective treatment) and 10^16 (severe chronic cases accounting for peak intensities and suffering between attacks). Even at the conservative end, preventing cluster headaches for life remains one of the highest-impact interventions accessible to individuals. Similar back-of-the-envelope calculations can be done to put in perspective each of the steps on the “logarithmic scale of help you can provide to someone”.


Scott Alexander in “Links For December 2024” (Dec 24 2025):

13: Alfredo Parra of Qualia Research Institute on cluster headaches. Cluster headaches are plausibly the most painful medical condition. If you ask a cluster patient to rate their pain, they’ll almost always say 10/10. Does that mean the headaches are twice as painful as a 5/10 condition? There are some philosophical reasons to expect pain to be logarithmic, so plausibly cluster headaches could be orders of magnitude more painful than the average condition. Once you internalize that possibility, it throws a wrench into normal QALY ratings and suggests that, even though cluster headaches are pretty rare, they might cause a substantial portion of the global burden of disease (or even a substantial portion of the suffering in the world). Some psychedelics, especially psilocybin and DMT, seem to treat cluster headaches very effectively, so the more you believe this reanalysis, the more interested you should be in figuring out how to turn these into an accessible therapy (see clusterbusters for more information on this aspect).

And more recently in “Open Thread 409” (Nov 24 2025):

2: Qualia Research Institute announces their spinoff effort ClusterFree. Cluster headaches (aka “suicide headaches”) are probably the most painful medical condition known to science, which makes them a natural priority for some utilitarians. They seem to be extremely treatable by psychedelics like psilocybin and DMT (including sub-hallucinogenic doses), so ClusterFree is working on getting governments to research this further and maybe get these drugs into the medical pipeline (cf. ketamine for depression). There’s an open letter here, and you can contact them here. The information for patients is at the bottom of this page.

Peter Singer in his recent piece “The Best Treatment for the Most Painful Medical Condition Is Illegal” (Dec 11 2025)

A recent article in Nature: Humanities and Social Science Communications found the funding provided in the United Kingdom for research on cluster headaches to be “orders of magnitude” less than that provided for multiple sclerosis, a condition that affects a similar number of people. The authors conclude that, given that we regard the provision of anesthesia for surgery to be essential, we should also recognize relief for extreme pain as essential. Finding ways to do so should warrant the highest funding priority.

A new initiative called Clusterfree has launched global open letters calling on governments to provide legal access to psychedelics for people with cluster headache. I have signed, and I hope that you will, too.

DMT for Cluster Headaches: Aborting and Preventing Extreme Pain with Tryptamines and Other Methods

“If we lived in a really sane society with a strong compassionate streak, every building would have something like a ‘Break in case of fire’ box… only this one would read ‘Break in case of cluster headache.’ Inside you’d find a pre‑charged DMT vape pen. That would be really nice.”

Announcement: Do you have experience using psychedelics to treat cluster headaches? Want to support science and advocacy in this area? Submit your personal and/or professional testimonial to our upcoming “ClusterFree” Open Letter initiative.


Sitting Down with Cluster Busters at Psychedelic Science 2025

One of the highlight moments for me at Psychedelic Science 2025 in Denver this June was conducting an interview for Bob Wold, founder of Cluster Busters, and Joe Stone, and Joe McKay who work alongside Bob in patient support and advocacy.  Our conversation covered a lot of ground, but I had one key strategic goal in mind: document, in their own words, why the humble DMT vape pen looks like a once‑in‑a‑generation breakthrough for the most painful condition that medicine has ever encountered.

“With a regular vape pen it’s usually one inhalation. Thirty seconds later the pain is gone. I hear a click in the middle of my brain and the attack is just off.” —Bob Wold

Their story plugs directly into QRI’s ongoing attempt to map the upper reaches of experience (QRI has the long-standing mission of mapping the state-space of consciousness, reverse engineer valence, and reduce suffering at scale). Our logarithmic scales of pleasure and pain shows that as one climbs up the pain (or pleasure) scales, phenomenal intensity rises far higher than common sense anticipates. The Heavy‑Tailed Valence hypothesis extends that insight to society at large and seeks to question the validity of current econometric approaches to collective wellbeing (cf. QALYs) in light of the fact that the extremes are not properly represented. From where we stand, it seems that a handful of wildly intense states do most of the moral damage (or good). Cluster headaches live in that fat tail, which is precisely why a 30‑second fix like DMT matters so much; perhaps as big of a collective hedonic breakthrough as, say, the discovery of anesthesia (in aggregate).

Put bluntly, if we care about total suffering, we need to care about cluster headaches. The time is now.


Interview Highlights Pertaining to DMT

  • DMT as an acute rescue
    One lungful (where the instructions typically say “three full breaths”) ends most attacks in under a minute. A second puff a minute later covers nearly all the rest. No tolerance shows up (acutely or chronically) which allows patients to repeat the dose whenever necessary.
  • Low psychedelic burden
    The dose is about a quarter of a psychedelic hit; enough to see some color enhancement but not enough for significant “trippiness”. Patients describe “a mild two‑beer buzz” or “the room takes on a golden tint” or “faint auras appear.” The mild level of psychedelia needed for this treatment makes bedside use practical, even for parents who need to stay functional the day after.
  • Why it beats psilocybin and LSD in the heat of battle
    Psilocybin and LSD still shine for cycle prevention, taken every five days, but they work on a timescale that makes them impractical for acute events. DMT is for the here‑and‑now (note Eleusinia founder says DMT also interrupt cycles according to her work at the retreat center). Joe Stone calls it “a game changer” because he can abort a 2AM ethical emergency (a cluster) and fall back asleep within 10 minutes. No need to have an expensive psychotherapy, a professional sitter, or trip killers on hand, let alone having to book a whole day to trip.
  • A hunch about endogenous DMT
    Bob’s shares his intuitive working model for how cluster headaches work (to be refuted or confirmed by science): an attack begins when natural DMT in the brain dips below a threshold (why do we even have DMT in our brains to begin with?). He hazards the guess that a quick DMT top‑up pulls the breaks and re‑establishes homeostasis. Others suggest that melatonin abnormalities in cluster patients add plausibility to his view, given the biochemical link between melatonin and endogenous tryptamine synthesis.
  • Pain drives the psychiatric condition, not the other way around
    One key insight I wanted to make sure to get on the record: chronic physical agony breeds depression, anxiety, and PTSD‑like flashbacks. Fix the pain and the mental distress often dissolves; no need for heroic doses or eight‑hour therapy sessions (as with e.g. psilocybin for depression specifically). Cultural over-emphasis on mental health as _the_ thing to treat with psychedelics might make sense from the point of view of a slowly expanding Overton Window; but the big hedonic payouts (freedom from hellish states of consciousness) are likely concentrated in their application to the reduction of extreme physical pain (see also).

Why This Matters

Alfredo Parra’s quantitative analysis suggests that cluster headaches may contribute more net misery than migraines, cancer pain, or even major depressive disorder once intensity is included (and a proper long-tail model and Monte Carlo simulations are taken into accont). Effective Altruist “pleasure-bean‑counters” (I say this affectionately!) please take note: extremely nasty but “rare” states can dominate the integral, and need urgent consideration.

From a consciousness‑research angle, the interview is another data point for why direct phenomenological investigation should guide ethics; here, patients, confronted with the reality of their own phenomenology, themselves have again clearly pioneered the treatment all the while mainstream research (unsurprisingly) slept through five decades of drug war.

Closing Thoughts

Imagine a fire‑alarm box on every hospital wall that reads “Break glass in case of cluster headache.” Inside we find a sober-looking, very boring but perfectly functional, pre‑filled DMT cartridge that delivers reliable 3mg hits (enough to feel a light buzz, not enough to trip significantly – certainly far short of any dose needed for entity contact or alien abduction experiences). This isn’t science fiction; it is what the data we’re seeing support.  Freedom from one of the most extreme demonic forces on Earth is, counterintuitively… Spice. Let’s shorten the path from patient innovation to standard‑of‑care and, in the process, erase one of the darkest corners of conscious experience forever. I believe we can achieve a Cluster-Free World within a few years if we put our minds and hearts to the task.

Hallucinations are not a problem at the doses we have people use and that seem to work the best, which are much smaller than a recreational dose. We aren’t recommending people take doses that will have them playing cards with a deer (you can’t trust them!). The doses are small (e.g. 1.5g of mushrooms). You’re supposed to get to about the “giggle”. Get to the “giggle point” and you’re good to go.Suicide or Psychedelics, Bob Wold at Horizons 2009


Resources and Further Reading:

How You Can Contribute:

  • Donate to Cluster Busters
  • Donate to QRI (earmark for “Cluster Headache Research and Advocacy”)
  • Donate to OPIS (Organization for the Prevention of Intense Suffering)
  • Share your testimonial if you’ve experienced relief through psychedelic therapy: Submit Here

Stay tuned for QRI’s upcoming Open Letter advocating for psychedelic access in treating severe pain conditions, the ClusterFree worldwide initiative.

Presidential Inaugural Address of Andrés Gómez Emilsson

[Epistemic Status: fiction (in most timelines, that is); in my lane, having fun]

Place: The Equatorial Republic (pop. ~190M)

Time: 2032

My fellow citizens of this great Equatorial Republic,

Today, as I stand before you having accepted the solemn responsibility of the presidency, I am humbled by your trust and energized by the possibilities that lie before us. This administration marks not just a change in leadership, but a fundamental paradigm shift in how we approach governance, human welfare, and our collective future.

A New Era of Compassion Through Science

On this first day in office, I am announcing the formation of the National Hedonic Research Initiative. Let me be clear: extreme suffering can be worse than death itself. Nowhere is this more evident than in the case of cluster headaches—aptly named “suicide headaches” by medical professionals, a condition where the pain is rated significantly more severe than childbirth, kidney stones, or even gunshot wounds.

Through Executive Order 001, I am establishing the Cluster Headache Elimination Commission with an initial $2 billion in funding. The data is clear: approximately 3 million people worldwide suffer from this condition, spending nearly 5 million person-days annually in extreme suffering rated 9/10 or higher on pain scales. This Commission will:

  1. Create a nationwide tryptamine research and distribution network, prioritizing low-dose N,N-DMT, psilocybin, and LSD trials based on compelling evidence that these compounds can not only abort attacks but extend remission periods indefinitely for many patients
  2. Establish 200 specialized treatment facilities across the nation within 6 months with mandatory oxygen therapy and other proven abortive treatments
  3. Fund 50 research laboratories dedicated to advancing our understanding of pain relief mechanisms and developing targeted interventions for these conditions based on patient-reported outcomes

Additionally, I am directing the Department of Health to create the Pharmaceutical Innovation Directive focusing on anti-tolerance compounds for chronic pain patients, next-generation flumazenil analogs to reverse benzodiazepine dependence, and targeted solutions for other iatrogenic conditions that have been unconscionably neglected. These extreme forms of suffering represent the deepest moral emergency in our society, and their elimination is our highest priority.

Mapping the Hedonic Landscape: Beyond QALY

For too long, our policies have been guided by economic indicators and inadequate health metrics like Quality-Adjusted Life Years (QALY). The QALY framework fundamentally fails us by treating all human experiences as linearly equivalent and by capping wellbeing at an arbitrary “perfect health” that ignores the vast territory of heightened human potential.

The empirical evidence is compelling: our current metrics systematically undervalue both the depths of intense human experiences and the heights of human flourishing. As a result, we’ve created policies that address widespread but moderate challenges while neglecting concentrated instances of profound human experiences – both positive and negative.

Today, I am commissioning the first comprehensive Hedonic Landscape Observatory—a scientific assessment of the full spectrum of human experience that will:

  1. Develop more sensitive and accurate measurements of diverse human experiences across the wellbeing spectrum
  2. Map the neurological correlates of resilience and positive states to complement our understanding of health
  3. Create economic feedback loops that systematically reward businesses and institutions that demonstrably enhance quality of life
  4. Develop a new economic indicator—the Consciousness-Weighted Prosperity Index—that will appear alongside GDP in all government reporting

This initiative will ensure that governance decisions are evaluated not just by economic impact, but by their effect on the actual lived quality of conscious experience of our citizens—taking into account the true depth and breadth of human flourishing available to us.

Game Theory and Consciousness: A New Political Framework

We stand at an evolutionary crossroads. The old politics operated on outdated models that failed to recognize the fundamental relationship between consciousness and our collective future. Today, we begin the transition to a political framework that explicitly acknowledges the quality of conscious experience—as central to governance.

By Executive Order 002, I am establishing the Consciousness-Economy Integration Commission tasked with creating explicit feedback loops between consciousness research and economic selection pressures. This commission will:

  1. Develop metrics that quantify the wellbeing-enhancing potential of technologies, enabling investors to select for innovations that genuinely improve quality of life
  2. Create tax incentives for businesses that demonstrably improve the lived experiences of their employees and customers
  3. Establish a public research platform exploring the positive potential of consciousness, ensuring that discoveries about phenomenological wellbeing directly influence market forces

This systematic exploration of consciousness is not merely academic—it will fundamentally reshape our economic landscape by ensuring that technologies and policies that enhance human flourishing systematically outcompete those that merely optimize for shallow metrics. The implications for environmental policy, social welfare, and international relations are profound and far-reaching.

Transcending Tribal Politics Through Psychological Understanding

From this day forward, international diplomacy will operate with a new level of psychological sophistication. Through the newly formed Department of Psychological Architecture Analysis, we will explicitly model the subagent structure of world leaders and political movements, identifying when narcissism, psychopathy, or tribal thinking is driving decision-making.

International coalitions will be formed not just around shared interests, but around shared psychological awareness. This administration will not hesitate to name pathological dynamics when they appear on the world stage, while offering a path forward through a consciousness-centric yet pragmatic approach to governance.

I am also directing our diplomatic corps to explore new modalities for high-stakes negotiations. We will establish a Diplomatic Innovation Laboratory to research the application of empathy-enhancing protocols in negotiation settings where entrenched psychological barriers prevent resolution. When trillions of dollars and millions of lives hang in the balance of international agreements, we cannot afford to have negotiations hijacked by psychological defense mechanisms and tribal identification.

Just as we now understand that the pain of cluster headaches is objectively more severe than a migraine, despite superficially similar descriptions, we must develop precise language and metrics for the psychological architectures that drive international conflict. They are real, distortionary, and far from game-theoretically optimal. Only by seeing these structures clearly—and developing reliable methods to transform them—can we hope to address existential challenges that require genuine cooperation.

Longevity: The Right of Every Citizen

While extreme suffering can be worse than death, unnecessary death itself remains a profound tragedy and represents an incalculable loss of human potential. Today, I announce the formation of the National Longevity Institute with initial funding of $10 billion, coordinating research across public and private sectors to dramatically extend healthy human lifespan.

This institute will prioritize three areas:

  1. Senolytics and cellular reprogramming technologies to reverse biological aging
  2. Neural preservation techniques to maintain cognitive function
  3. Prevention of age-related suffering states through targeted interventions

The benefits of this research will not be reserved for the privileged few, but made available to every citizen as a basic right. Age-related suffering is not inevitable, and this administration will not accept it as such.

The Science of Awakening: Soteriology as a Research Target

Even as we pursue longevity, we must confront a fundamental truth: all things remain impermanent. Today, I am establishing the Institute for Contemplative Sciences with a mission to develop a rigorous scientific understanding of what traditions across time and cultures have called “awakening,” “enlightenment,” or “liberation.”

This research program will:

  1. Systematically study how humans throughout history have made peace with impermanence and transcended existential suffering
  2. Investigate the neurobiological and phenomenological correlates of awakening experiences across contemplative traditions
  3. Develop scalable, secular methods to help citizens process mortality, grief, and existential concerns within our scientific worldview
  4. Create interdisciplinary teams combining neuroscientists, contemplatives, philosophers, and clinicians to bridge ancient wisdom with modern scientific rigor

The ultimate human challenge is not merely to extend life, but to discover how to be fundamentally okay with the impermanent nature of existence. While various religious and philosophical traditions have offered paths to this goal for millennia, we now have the scientific tools to explore these states with unprecedented precision.

By creating a dialogue between contemplative wisdom and scientific method, we can forge new pathways for humanity to face its deepest existential challenges. This is not merely a spiritual pursuit—it is a practical necessity for a civilization grappling with the fundamental questions of meaning and mortality in an age of unprecedented technological power.

Understanding Exceptional States of Consciousness

The most profound states of human consciousness remain largely unexplored territory in scientific research. Today, I am directing the National Institutes of Health to establish the Center for Exceptional States of Consciousness (aka. The Super-Shulgin Academy) with a $5 billion initial investment, tasked with making sense of profoundly positive experiences across the full spectrum of chemically-facilitated and meditation-induced states.

This Center will:

  1. Create standardized protocols for psychedelic research, including 5-MeO-DMT with essential safeguards and contraindication screening, recognizing that while beneficial for many, it can induce challenging experiences in others—understanding these variables is crucial for responsible application
  2. Fund 25 dedicated research facilities specializing in Jhana acceleration techniques and other contemplative practices that achieve similar states without pharmacological intervention
  3. Develop a comprehensive empirical framework mapping the neural correlates of these heightened states while investigating both beneficial outcomes and adverse reactions to create predictive models for personalized approaches
  4. Prioritize sustainable MDMA production and research as a north star intervention, focusing on its potential for treating PTSD and enhancing empathetic connection while minimizing cardiovascular impact and developing protocols to mitigate tolerance and neurotoxicity concerns
  5. Translate findings into scalable interventions for depression, anxiety, and existential distress, ensuring that safety, accessibility, and individual neuropsychological differences guide all protocols

These states represent extraordinary territories of human wellbeing—regions of experience that offer not only therapeutic potential but a scientific window into the furthest reaches of human potential that we have barely begun to understand. Our commitment is to explore these states with both scientific rigor and ethical care, recognizing both their profound potential and the need for responsible stewardship.

Expanding Our Moral Circle: Non-Human Animal Consciousness

Our commitment to understanding consciousness and reducing suffering must extend beyond our own species. Today, I am establishing the Interspecies Consciousness Research Initiative with a dual mandate: rigorous scientific exploration and practical harm reduction.

This Initiative will:

  1. Develop objective metrics to quantify suffering in non-human animals, with immediate focus on factory-farmed animals where the concentration of suffering is most acute
  2. Allocate $3 billion annually to research and implement improved welfare standards for farmed animals while simultaneously investing in cultured meat technologies and plant-based alternatives
  3. Create a roadmap for the gradual, culturally sensitive phasing out of the most harmful animal agriculture practices over the coming decades, aligning economic incentives with ethical progress
  4. Establish the Wild Animal Welfare Research Program to cautiously explore the complex ethical landscape of wild animal suffering, acknowledging the immense scientific and ecological challenges involved

The ethical imperative is clear, but so is the need for careful, evidence-based approaches. We will neither rush interventions that could have unintended consequences nor hide behind complexity as an excuse for inaction when suffering is demonstrable and solutions are feasible. This balanced approach recognizes our ethical responsibilities without compromising scientific rigor or cultural realities.

Transforming Education: Experience, Don’t Memorize

A key pillar of this administration will be fundamentally reimagining education. Today, I announce the Consciousness Education Initiative that will transform how we develop young minds. This initiative rejects both outdated rote learning and any form of ideological indoctrination. Instead, it embraces a “see for yourself” approach where students:

  1. Learn meditation techniques alongside mathematics, building empirical skills for exploring internal states
  2. Study their own consciousness with the same rigor they apply to studying literature, using first-person methods complemented by third-person science
  3. Develop critical thinking by becoming aware of their own cognitive biases and subagent structures
  4. Understand the psychological architectures that drive political beliefs through evidence-based empirical investigations

The goal is not to tell students what to think about consciousness, but to give them the tools to explore their own minds with scientific precision and philosophical depth. This approach builds intellectual independence—teaching students to verify claims through direct experience rather than accepting them on authority, whether in consciousness studies or any other domain.

A Call to Action

My fellow citizens, I do not promise that these ambitious goals will be easy to achieve. They will require not just government action, but a transformation in how we approach science, governance, and our very understanding of what it means to be human.

But the stakes could not be higher. We have the opportunity to eliminate forms of suffering that have plagued humanity throughout history, to extend healthy life, to create social systems that support human flourishing, and to understand the very foundations of consciousness itself.

This is not a partisan agenda, but a human one. In fact, of consciousness itself. It transcends traditional political divisions and speaks to our shared desire for a world with less suffering and more joy, less confusion and more clarity, less conflict and more cooperation.

Let us begin this journey together, guided by compassion, informed by science, and dedicated to the proposition that the quality of conscious experience matters fundamentally—and that we have both the capability and the responsibility to improve it, in ourselves, our loved ones, and in the field at large.

Thank you, and may we move forward with wisdom, courage, and clear-eyed determination.

Infinite bliss!

[The crowd erupts in thunderous applause]

And now, ladies and gentlemen, please welcome the voted ‘most hedonic’ pop sensation of the year, performing their chart-topping anthem inspired by our vision for the future!

[Cue massive flashy fireworks as the stage transforms. Spotlights sweep across a diverse crowd of all ages beginning to dance as the music starts. Children, seniors, and everyone in between move to the rhythm. The singer emerges from beneath the stage on a rising platform surrounded by dancers in colorful neuron-patterned costumes, launching into their hit song about consciousness, wellbeing and the dawning of a new era of understanding…]

Conscious Dawn” – Presidential Lyrics

Ancient wisdom meets the future’s light
Through pain’s darkest valleys, we’ll find the heights
Mapping consciousness beyond what we’ve known
A nation where suffering won’t reign on the throne

Tribal boundaries dissolve in our sight
As senolytics set our cells aright
The hedonic landscape unfolds like a scroll
Where DMT whispers truths to the soul

From cluster headaches to enlightened minds
Transcending metrics that keep us blind
Our moral circle widens beyond human skin
Wild animal welfare, a new dawn begins

Science awakens what sages once taught
Not just to live long, but find what we’ve sought
A republic where bliss is more than a dream
Infinite consciousness—our birthright supreme

Open Letter to the TPOT Community on the Topic of Animal Suffering: Enlightenment, Tanha, and Kiki Qualia

Dear TPOT community,

I’ve been noticing an increasingly common perspective in our discussions that I feel compelled to address. There seems to be a growing belief that non-human animals are somehow “enlightened by default” or exist in a state free from tanha (craving, aversion, and the resulting suffering). I’ve seen numerous posts suggesting that non-human animals are somehow naturally free from the mental patterns that create suffering in humans. While I deeply appreciate the sentiment behind this view – as indeed, animals do seem to access deeply bouba states more readily than most humans realize, and their capacity for pleasure is real and ethically relevant – I believe this represents a fundamental misunderstanding about animal consciousness that needs careful examination.

The probability that, say, free range cows (or other non-human animals in general) are experiencing constant bliss, lack tanha, or are “enlightened by default” is, by my estimation, very low (<0.2%). A claim of enlightenment-by-default requires extraordinary evidence, and what we see points in the opposite direction. Let me break this down from a qualia-centric perspective:

Consider first the clear evidence of suffering in prey animals – species like deer, rabbits, or gazelles must maintain constant vigilance against predators, a state that phenomenologically manifests as a persistent kiki-like tension in consciousness. This baseline of anxiety and alertness is fundamentally incompatible with persistent non-dual states. A prey animal experiencing constant bliss would be rapidly selected against in an environment with predators.

Even predators themselves are not free from tanha – we see intense craving manifesting in their sexual frustration during mating seasons, their constant drive for status within social hierarchies, and their restless search for food even when not immediately hungry. The apparent ease with which a lion rests in the sun masks the intense loops of desire and aversion that characterize their conscious experience.

In domesticated animals like cattle, we see equally clear evidence of craving, aversion, and suffering in their daily lives. Cows display intense maternal distress when separated from their calves, with both mother and offspring showing signs of anxiety and distress that can persist for days. They engage in competition for food resources and establish complex social hierarchies that generate ongoing stress for individuals lower in the pecking order. Their food-seeking behaviors demonstrate clear patterns of craving, and they exhibit territorial behaviors that indicate attachment and aversion patterns similar to those we recognize in humans.

The “gazelle shaking off trauma” observation that’s often cited in these discussions actually reinforces the presence of suffering rather than its absence. This isn’t evidence of enlightenment – it’s evidence of an evolved mechanism for rapid state-switching to maintain function. The ability to quickly return to a baseline state of persistent vigilance and anxiety after a threatening encounter is precisely what you’d expect from an organism optimized for survival rather than one experiencing persistent non-dual awareness.

Non-human animals are clearly stuck in loops of craving and aversion. Consider a dog who insists on affection or food: scratching at the door, howling, and persistently demanding attention. These behaviors are obvious manifestations of craving, and, as Rob Burbea points out, all craving is fundamentally based on patterns of body tension. These patterns are not unique to humans but are basic features of animal consciousness. Tanha is thus near or completely ubiquitous in the animal kingdom.

From a neurophysiological perspective, as David Pearce (who, notably, uses the term “non-human animals” to remind us that we too are animals, and that creating artificial distinctions makes it easier to rationalize a sense of separation) has consistently emphasized, we see remarkable conservation of emotional circuitry across mammals. The same neural architectures that give rise to fear, anxiety, and suffering in humans are present in cows and other animals. If cows had somehow evolved a fundamentally different way of experiencing consciousness, we would expect to see major divergences in neural architecture; we don’t see such differences. In fact, the evidence suggests that the capacity for suffering predates the development of the rational, linguistic mind. While humans can use our frontal lobes to rationalize and contextualize pain and suffering, this higher-order cognition isn’t a prerequisite for suffering – quite the contrary.

Consider that pigs have the emotional and cognitive capacity roughly equivalent to prelinguistic toddlers. They experience raw emotions without the buffer of linguistic rationalization that adult humans possess. Chimpanzees show clear signs of depression-like behaviors following social defeats, PTSD-like symptoms after conflict, long-term emotional impacts from loss of status, and evidence of social anxiety and strategic behavior. Birds, despite being separated from mammals by hundreds of millions of years of evolution, display sophisticated emotional responses including spite and vindictiveness. These observations all point to the same conclusion: the mechanisms behind tanha are ancient and deeply preserved across the animal kingdom. The capacity for suffering doesn’t require complex cognition or human-level linguistic capacities – it’s a fundamental feature of animal sentience that evolution has maintained and elaborated upon.

The “animals are enlightened” view seems to commit what I call the “blame language fallacy” – the assumption that consciousness without language or higher order cognition is in “its natural state” and must somehow be more pure or pleasant than our modern human experience. This is reminiscent of the noble savage myth, but applied to animal consciousness.

When we look at empirical evidence from animal welfare science (cortisol levels, behavioral indicators, physiological measures), we consistently see that animals experience a wide range of emotional states, including significant suffering. If animals were naturally enlightened, we wouldn’t observe the dramatic improvements in welfare metrics when we enhance their living conditions.

I suspect this view serves several psychological functions:

  • It provides emotional comfort about the natural world
  • It suggests an easier solution to suffering than actually exists
  • It allows for a form of motivated reasoning about animal agriculture (itself likely one of the biggest sources of suffering in the world)

As someone deeply interested in consciousness and its varieties, as well as no-nonsense suffering reduction tech, I have to emphasize that while animals certainly can experience positive states, they are subject to the same fundamental constraints and physiology that shape all conscious experience on this planet. The goal should be to understand and work within these constraints to reduce suffering, not to pretend they don’t exist, as I see is happening more and more.

The path forward isn’t to romanticize animal consciousness but to better understand it in all its complexity. This requires engaging with the empirical evidence and being willing to update our views when they conflict with our preferred narratives about the nature of consciousness and its place in nature.

Finally, by my estimation it is quite likely that animal valence follows long-tail distributions (just as most things do in the context of consciousness). I think it will be crucial to identify the main species who suffer the most (likely not humans!) and help them first.

Sincerely,
Andres 🙂

Costs of Embodiment

[X-Posted @ The EA Forum]

By Andrés Gómez Emilsson

Digital Sentience

Creating “digital sentience” is a lot harder than it looks. Standard Qualia Research Institute arguments for why it is either difficult, intractable, or literally impossible to create complex, computationally meaningful, bound experiences out of a digital computer (more generally, a computer with a classical von Neumann architecture) include the following three core points:

  1. Digital computation does not seem capable of solving the phenomenal binding or boundary problems.
  2. Replicating input-output mappings can be done without replicating the internal causal structure of a system.
  3. Even when you try to replicate the internal causal structure of a system deliberately, the behavior of reality at a deep enough level is not currently understood (aside from how it behaves in light of inputs-to-outputs).

Let’s elaborate briefly:

The Binding/Boundary Problem

  1. A moment of experience contains many pieces of information. It also excludes a lot of information. Meaning that, a moment of experience contains a precise, non-zero, amount of information. For example, as you open your eyes, you may notice patches of blue and yellow populating your visual field. The very meaning of the blue patches is affected by the presence of the yellow patches (indeed, they are “blue patches in a visual field with yellow patches too”) and thus you need to take into account the experience as a whole to understand the meaning of all of its parts.
  2. A very rough, intuitive, conception of the information content of an experience can be hinted at with Gregory Bateson’s (1972) “a difference that makes a difference”. If we define an empty visual field as containing zero information, it is possible to define an “information metric” from this zero state to every possible experience by counting the number of Just Noticeable Differences (JNDs) (Kingdom & Prins, 2016) needed to transform such empty visual field into an arbitrary one (note: since some JND are more difficult to specify than others, a more accurate metric should also take into account the information cost of specifying the change in addition to the size of the change that needs to be made). It is thus evident to see that one’s experience of looking at a natural landscape contains many pieces of information at once. If it didn’t, you would not be able to tell it apart from an experience of an empty visual field.
  3. The fact that experiences contain many pieces of information at once needs to be reconciled with the mechanism that generates such experiences. How you achieve this unity of complex information starting from a given ontology with basic elements is what we call “the binding problem”. For example, if you believe that the universe is made of atoms and forces (now a disproven ontology), the binding problem will refer to how a collection of atoms comes together to form a unified moment of experience. Alternatively, if one’s ontology starts out fully unified (say, assuming the universe is made of physical fields), what we need to solve is how such a unity gets segmented out into individual experiences with precise information content, and thus we talk about the “boundary problem”.
  4. Within the boundary problem, as Chris Percy and I argued in Don’t Forget About the Boundary Problem! (2023), the phenomenal (i.e. experiential) boundaries must satisfy stringent constraints to be viable. Namely, among other things, phenomenal boundaries must be:
    1. Hard Boundaries: we must avoid “fuzzy” boundaries where information is only “partially” part of an experience. This is simply the result of contemplating the transitivity of the property of belonging to a given experience. If a (token) sensation A is part of a visual field at the same time as a sensation B, and B is present at the same time as C, then A and C are also both part of the same experience. Fuzzy boundaries would break this transitivity, and thus make the concept of boundaries incoherent. As a reductio ad absurdum, this entails phenomenal boundaries must be hard.
    2. Causally significant (i.e. non-epiphenomenal): we can talk about aspects of our experience, and thus we can know they are part of a process that grants them causal power. More so, if structured states of consciousness did not have causal effects in some way isomorphic to their phenomenal structure, evolution would simply have no reason to recruit them for information processing. Albeit epiphenomenal states of consciousness are logically coherent, the situation would leave us with no reason to believe, one way or the other, that the structure of experience would vary in a way that mirrors its functional role. On the other hand, states of consciousness having causal effects directly related to their structure (the way they feel like) fits the empirical data. By what seems to be a highly overdetermined Occam’s Razor, we can infer that the structure of a state of consciousness is indeed causally significant for the organism.
    3. Frame-invariant: whether a system is conscious should not depend on one’s interpretation of it or the point of view from which one is observing it (see appendix for Johnson’s (2015) detailed description of frame invariance as a theoretical constraint within the context of philosophy of mind).
    4. Weakly emergent on the laws of physics: we want to avoid postulating either that there is a physics-violating “strong emergence” at some level of organization (“reality only has one level” – David Pearce) or that there is nothing peculiar happening at our scale. Bound, casually significant, experiences could be akin to superfluid helium. Namely, entailed by the laws of physics, but behaviorally distinct enough to play a useful evolutionary role.
  5. Solving the binding/boundary problems does not seem feasible with a von Neumann architecture in our universe. The binding/boundary problem requires the “simultaneous” existence of many pieces of information at once, and this is challenging using a digital computer for many reasons:
    1. Hard boundaries are hard to come by: looking at the shuffling of electrons from one place to another in a digital computer does not suggest the presence of hard boundaries. What separates a transistor’s base, collector, and emitter from its immediate surroundings? What’s the boundary between one pulse of electricity and the next? At best, we can identify functional “good enough” separations, but no true physics-based hard boundaries.
    2. Digital algorithms lack frame invariance: how you interpret what a system is doing in terms of classic computations depends on your frame of reference and interpretative lens.
    3. The bound experiences must themselves be causally significant. While natural selection seemingly values complex bound experiences, our digital computer designs precisely aim to denoise the system as much as possible so that the global state of the computer does not influence in any way the lower-level operations. At the algorithmic level, the causal properties of a digital computer as a whole, by design, are never more than the strict sum of their parts.

Matching Input-Output-Mapping Does Not Entail Same Causal Structure

Even if you replicate the input-output mapping of a system, that does not mean you are replicating the internal causal structure of the system. If bound experiences are dependent on specific causal structures, they will not happen automatically without considerations for the nature of their substrate (which might have unique, substrate-specific, causal decompositions). Chalmers’ (1995) “principle of organizational invariance” assumes that replicating a system’s functional organization at a fine enough grain will reproduce identical conscious experiences. However, this may be question-begging if bound experiences require holistic physical systems (e.g. quantum coherence). In such a case, the “components” of the system might be irreducible wholes, and breaking them down further would result in losing the underlying causal structure needed for bound experiences. This suggests that consciousness might emerge from physical processes that cannot be adequately captured by classical functional descriptions, regardless of their granularity.

More so, whether we realize it or not, it is always us (indeed complex bound experiences) who interpret the meaning of the input and the output of a physical system. It is not interpreted by the system itself. This is because the system has no real “points of view” from which to interpret what is going on. This is a subtle point, and will merely mention it for now, but a deep exposition of this line of argument can be found in The View From My Topological Pocket (2023).

We more so would point out that the system that is smuggling a “point of view” to interpret a digital computer’s operations is in the human who builds, maintains, and utilizes it. If we want a system to create its “own point of view” we will need to find the way for it to bind the information in a (1) “projector”/screen, (2) an actual point of view proper, or (3) the backwards lightcone that feeds into such a point of view. As argued, none of these are viable solutions.

Reality’s Deep Causal Structure is Poorly Understood

Finally, another key consideration that has been discussed extensively is that the very building blocks of reality have unclear, opaque causal structures. Arguably, if we want to replicate the internal causal structure of a conscious system, the classical input-output mapping is therefore not enough. If you want to ensure that what is happening inside the system has the same causal structure as its simulated counterpart, you would also need to replicate how the system would respond to non-standard inputs, including x-rays, magnetic fields, and specific molecules (e.g. Xenon isotopes).

These ideas have all been discussed at length in articlespodcastspresentations, and videos. Now let’s move on to a more recent consideration we call “Costs of Embodiment”.

Costs of Embodiment

Classical “computational complexity theory” is often used as a silver bullet “analytic frame” to discount the computational power of systems. Here is a typical line of argument: under the assumption that consciousness isn’t the result of implementing a quantum algorithm per se, the argument goes, then there is “nothing that it can do that you couldn’t do with a simulation of the system”. This, however, is neglecting the complications that come from instantiating a system in the physical world with all that it entails. To see why, we must first explain the nature of this analytic style in more depth:

Introduction to Computational Complexity Theory

Computational complexity theory is a branch of computer science that focuses on classifying computational problems according to their inherent difficulty. It primarily deals with the resources required to solve problems, such as time (number of steps) and space (memory usage).

Key concepts in computational complexity theory include:

  1. Big O notation: Used to describe the upper bound of an algorithm’s rate of growth.
  2. Complexity classes: Categories of problems with similar resource requirements (e.g., P, NP, PSPACE).
  3. Time complexity: Measure of how the running time increases with the size of the input.
  4. Space complexity: Measure of how memory usage increases with the size of the input.

In brief, this style of analysis is suited for analyzing the properties of algorithms that are implementation-agnostic, abstract, and interpretable in the form of pseudo-code. Alas, the moment you start to ground these concepts in the real physical constraints to which life is subjected, the relevance and completeness of the analysis starts to fall apart. Why? Because:

  1. Big O notation counts how the number of steps (time complexity) or number of memory slots (space complexity) grows with the size of the input (or in some cases size of the output). But not all steps are created equal:
    1. Flipping the value of a bit might be vastly cheaper in the real world than moving the value of a bit to another location that is very (physically far) in the computer.
    2. Likewise, some memory operations are vastly more costly than others: in the real world you need to take into account the cost of redundancy, distributed error correction, and entropic decay of structures not in use at the time.
  2. Not all inputs and outputs are created equal. Taking in some inputs might be vastly more costly than others (e.g. highly energetic vibrations that shake the system apart mean something to a biological organism as it needs to adapt to the possible stress induced by the nature of the input, expressing certain outputs might be much more costly than others, as the organism needs to reconfigure itself to deliver the result of the computation, a cost that isn’t considered by classical computational complexity theory).
  3. Interacting with a biological system is a far more complex activity than interacting with, say, logic gates and digital memory slots. We are talking about a highly dynamic, noisy, soup of molecules with complex emergent effects. Defining an operation in this context, let alone its “cost”, is far from trivial.
  4. Artificial computing architectures are designed, implemented, maintained, reproduced, and interpreted by humans who, if we are to believe already have powerful computational capabilities, are giving the system an unfair advantage over biological systems (which require zero human assistance).

Why Embodiment May Lead to Underestimating Costs

Here is a list of considerations that highlight the unique costs that come with real-world embodiment for information-processing systems beyond the realm of mere abstraction:

  1. Physical constraints: Traditional complexity theory often doesn’t account for physical limitations of real-world systems, such as heat dissipation, energy consumption, and quantum effects.
  2. Parallel processing: Biological systems, including brains, operate with massive adaptive parallelism. This is challenging to replicate in classical computing architectures and may require different cost analyses.
  3. Sensory integration: Embodied systems must process and integrate multiple sensory inputs simultaneously, which can be computationally expensive in ways not captured by standard complexity measures.
  4. Real-time requirements: Embodied systems often need to respond in real-time to environmental stimuli, adding temporal constraints that may increase computational costs.
  5. Adaptive learning: The ability to learn and adapt in real-time may incur additional computational costs not typically considered in classical complexity theory.
  6. Robustness to noise: Physical systems must be robust to environmental noise and internal fluctuations, potentially requiring redundancy and error-correction mechanisms that increase computational costs.
  7. Energy efficiency: Biological systems are often highly energy-efficient, which may come at the cost of increased complexity in information processing.
  8. Non-von Neumann architectures: Biological neural networks operate on principles different from classical computers, potentially involving computational paradigms not well-described by traditional complexity theory.
  9. Quantum effects: At the smallest scales, quantum mechanical effects may play a role in information processing, adding another layer of complexity not accounted for in classical theories.
  10. Emergent properties: Complex systems may exhibit physical emergent properties that arise from the interactions of simpler components and as well as phase transitions, potentially leading to computational costs that are difficult to predict or quantify using standard methods.

See appendix for a concrete example of applying these considerations to an abstract and embodied object recognition system (example provided by Kristian Rönn).

Case Studies:

1.  2D Computers

It is well known in classical computing theory that a 2D computer can implement anything that an n-dimensional computer can do. Namely, because it is possible to create a 2D Turing Machine capable of simulating arbitrary computers of this class (to the extent that there is a computational complexity equivalence between an n-dimensional computer and a 2D computer), we see that (at the limit) the same runtime complexity as the original computer in 2D should be achievable.

However, living in a 2D plane comes with enormous challenges that highlight the cost of embodiment present in a given media. In particular, we will see that the *routing costs* of information will grow really fast, as the channels that connect between different parts of the computer will need to take turns in order to allow for the crossed wires to transmit information without saturating the medium of (wave/information) propagation.

A concrete example here comes from examining what happens when you divide a circle into areas. Indeed, this is a well-known math problem, where you are supposed to derive a general formula for the number of areas by which a circle gets divided when you connect n (generally placed) points in its periphery. The takeaway of this exercise is often to point out that even though at first the number of areas seem to be powers of 2 (2, 4, 8, 16…) eventually the pattern is broken (the number after 16 is, surprisingly, 31 and not 32).

For the purpose of this example we shall simply focus on the growth of edges vs. the growth of crossings between the edges as we increase the number of nodes. Since every pair of nodes has an edge, the formula for the number of edges as a function of the number of nodes n is: n choose 2. Similarly, any four points define a single unique crossing, and thus the formula for the number of crossings is: n choose 4. When n is small (6 or less), the number of crossings is smaller or equal to the number of edges. But as soon as we hit 7 nodes, the number of crossings dominates over the number of edges. Asymptotically, in fact, the growth of edges is O(n^2) using the Big O notation, whereas the number of crossings ends up being O(n^4), which is much faster. If this system is used in the implementation of an algorithm that requires every pair of nodes to interact with each other once, we may at first be under the impression that the complexity will grow as O(n^2). But if this system is embodied, messages between the nodes will start to collide with each other at the crossings. Eventually, the number of delays and traffic jams caused by the embodiment of the system in 2D will dominate the time complexity of the system.

2. Blind Systems: Bootstrapping a Map Isn’t Easy

A striking challenge that biological systems need to tackle to instantiate moments of experience with useful information arises when we consider the fact that, at conception, biological systems lack a pre-existing “ground truth map” of their own components, i.e. where they are, and where they are supposed to be. In other words, biological systems somehow bootstrap their own internal maps and coordination mechanisms from a seemingly mapless state. This feat is remarkable given the extreme entropy and chaos at the microscopic level of our universe.

Assembly Theory (AT) (2023) provides an interesting perspective on this challenge. AT conceptualizes objects not as simple point particles, but as entities defined by their formation histories. It attempts to elucidate how complex, self-organizing systems can emerge and maintain structure in an entropic universe. However, AT also highlights the intricate causal relationships and historical contingencies underlying such systems, suggesting that the task of self-mapping is far from trivial.

Consider the questions this raises: How does a cell know its location within a larger organism? How do cellular assemblies coordinate their components without a pre-existing map? How are messages created and routed without a predefined addressing system and without colliding with each other? In the context of artificial systems, how could a computer bootstrap its own understanding of its architecture and component locations without human eyes and hands to see and place the components in their right place?

These questions point to the immense challenge faced by any system attempting to develop self-models or internal mappings from scratch. The solutions found in biological systems might potentially rely on complex, evolved mechanisms that are not easily replicated in classical computational architectures. This suggests that creating truly self-understanding artificial systems capable of surviving in a hostile, natural environment, may require radically different approaches than those currently employed in standard computing paradigms.

How Does the QRI Model Overcome the Costs of Embodiment?

This core QRI article presents a perspective on consciousness and the binding problem that aligns well with our discussion of embodiment and computational costs. It proposes that moments of experience correspond to topological pockets in the fields of physics, particularly the electromagnetic field. This view offers several important insights:

  1. Frame-invariance: The topology of vector fields is Lorentz invariant, meaning it doesn’t change under relativistic transformations. This addresses the need for a frame-invariant basis for consciousness, which we identified as a challenge for traditional computational approaches.
  2. Causal significance: Topological features of fields have real, measurable causal effects, as exemplified by phenomena like magnetic reconnection in solar flares. This satisfies the requirement for consciousness to be causally efficacious and not epiphenomenal.
  3. Natural boundaries: Topological pockets provide objective, causally significant boundaries that “carve nature at its joints.” This contrasts with the difficulty of defining clear system boundaries in classical computational models.
  4. Temporal depth: The approach acknowledges that experiences have a temporal dimension, potentially lasting for tens of milliseconds. This aligns with our understanding of neural oscillations and provides a natural way to integrate time into the model of consciousness.
  5. Embodiment costs: The topological approach inherently captures many of the “costs of embodiment” we discussed earlier. The physical constraints, parallel processing, sensory integration, and real-time requirements of embodied systems are naturally represented in the complex topological structures of the brain’s electromagnetic field.

This perspective suggests that the computational costs of consciousness may be even more significant than traditional complexity theory would indicate. It implies that creating artificial consciousness would require not just simulating neural activity, but replicating the precise topological structures of electromagnetic fields in the brain. This is a far more challenging task than conventional AI approaches.

Moreover, this view provides a potential explanation for why embodied systems like biological brains are so effective at producing consciousness. The physical structure of the brain, with its complex networks of neurons and electromagnetic fields, may be ideally suited to creating the topological pockets that correspond to conscious experiences. This suggests that embodiment is not just a constraint on consciousness, but a fundamental enabler of it.

Furthermore, there is a non-trivial connection between topological segmentation and resonant modes. The larger a topological pocket is, the lower the frequency of the resonant modes can be. This, effectively, is broadcasted to every region within the pocket (much akin how any spot on the surface of an acoustic guitar expresses the vibrations of the guitar as a whole). Thus, topological segmentation, quite conceivably, might be implicated in the generation of maps for the organism to self-organize around (cf. bioelectric morphogenesis according to Michael Levin, 2022). Steven Lehar (1999) and Michael E. Johnson (2018) in particular have developed really interesting conceptual frameworks for how harmonic resonance might be implicated in the computational character of our experience. The QRI insight that topology can mediate resonance, further complicates the role of phenomenal boundaries in the computational role of consciousness.

Conclusion and Path Forward

In conclusion, the costs of embodiment present significant challenges to creating digital sentience that traditional computational complexity theory fails to fully capture. The QRI solution to the boundary problem, with its focus on topological pockets in electromagnetic fields, offers a promising framework for understanding consciousness that inherently addresses many of these embodiment costs. Moving forward, research should focus on: (1) developing more precise methods to measure and quantify the costs of embodiment in biological systems, (2) exploring how topological features of electromagnetic fields could be replicated or simulated in artificial systems, and (3) investigating the potential for hybrid systems that leverage the natural advantages of biological embodiment while incorporating artificial components (cf. Xenobots). By pursuing these avenues, we may unlock new pathways towards creating genuine artificial consciousness while deepening our understanding of natural consciousness.

It is worth noting that the QRI mission is to “understand consciousness for the benefit of all sentient beings”. Thus, figuring out the constraints that give rise to computationally non-trivial bound experiences is one key piece of the puzzle: we don’t want to accidentally create systems that are conscious and suffering and become civilizationally load-bearing (e.g. organoids animated by pain or fear).

In other words, understanding how to produce conscious systems is not enough. We need to figure out how to (a) ensure that they are animated by information-sensitive gradients of bliss, and (b) how being empowered by the computational properties of consciousness can lean into more benevolent mind architectures. Namely, architectures that care about their wellbeing and the wellbeing of all sentient beings. This is an enormous challenge; clarifying the costs of embodiment is one key step forward, but part of an ecosystem of actions and projects needed for the robust positive impact of consciousness research for the wellbeing of all sentient beings.

Acknowledgments:

This post was written at the July 2024 Qualia Research Institute Strategy Summit in Sweden. It comes about as a response to incisive questions by Kristian Rönn on QRI’s model of digital sentience. Many thanks to Curran Janssen, Oliver Edholm, David Pearce, Alfredo Parra, Asher Soryl, Rasmus Soldberg, and Erik Karlson, for brainstorming, feedback, suggesting edits, and the facilitation of this retreat.

Appendix

Excerpt from Michael E. Johnson’s Principia Qualia (2015) on Frame Invariance (pg. 61)

What is frame invariance?

A theory is frame-invariant if it doesn’t depend on any specific physical frame of reference, or subjective interpretations to be true. Modern physics is frame-invariant in this way: the Earth’s mass objectively exerts gravitational attraction on us regardless of how we choose to interpret it. Something like economic theory, on the other hand, is not frame-invariant: we must interpret how to apply terms such as “GDP” or “international aid” to reality, and there’s always an element of subjective judgement in this interpretation, upon which observers can disagree.

Why is frame invariance important in theories of mind?

Because consciousness seems frame-invariant. Your being conscious doesn’t depend on my beliefs about consciousness, physical frame of reference, or interpretation of the situation – if you are conscious, you are conscious regardless of these things. If I do something that hurts you, it hurts you regardless of my belief of whether I’m causing pain. Likewise, an octopus either is highly conscious, or isn’t, regardless of my beliefs about it.[a] This implies that any ontology that has a chance of accurately describing consciousness must be frame-invariant, similar to how the formalisms of modern physics are frame-invariant.

In contrast, the way we map computations to physical systems seems inherently frame-dependent. To take a rather extreme example, if I shake a bag of popcorn, perhaps the motion of the popcorn’s molecules could – under a certain interpretation – be mapped to computations which parallel those of a whole-brain emulation that’s feeling pain. So am I computing anything by shaking that bag of popcorn? Who knows. Am I creating pain by shaking that bag of popcorn? Doubtful… but since there seems to be an unavoidable element of subjective judgment as to what constitutes information, and what constitutes computation, in actual physical systems, it doesn’t seem like computationalism can rule out this possibility. Given this, computationalism is frame-dependent in the sense that there doesn’t seem to be any objective fact of the matter derivable for what any given system is computing, even in principle.

[a] However, we should be a little bit careful with the notion of ‘objective existence’ here if we wish to broaden our statement to include quantum-scale phenomena where choice of observer matters.

Example of Cost of Embodiment by Kristian Rönn

Abstract Scenario (Computational Complexity):

Consider a digital computer system tasked with object recognition in a static environment. The algorithm processes an image to identify objects, classifies them, and outputs the results.

Key Points:

  • The computational complexity is defined by the algorithm’s time and space complexity (e.g., O(n^2) for time, O(n) for space).
  • Inputs (image data) and outputs (object labels) are well-defined and static.
  • The system operates in a controlled environment with no physical constraints like heat dissipation or energy consumption.

However, this abstract analysis is extremely optimistic, since it doesn’t take the cost of embodiment into account.

Embodied Scenario (Embodied Complexity):

Now, consider a robotic system equipped with a camera, tasked with real-time object recognition and interaction in a dynamic environment.

Key Points and Costs:

  1. Real-Time Processing:
    • The robot must process images in real-time, requiring rapid data acquisition and processing, which creates practical constraints.
    • Delays in computation can lead to physical consequences, such as collisions or missed interactions.
  2. Energy Consumption:
    • The robot’s computational tasks consume power, affecting the overall energy budget.
    • Energy management becomes crucial, balancing between processing power and battery life.
  3. Heat Dissipation:
    • High computational loads generate heat, necessitating cooling mechanisms, requiring additional energy. Moreover, this creates additional costs/waste in the embodied system.
    • Overheating can degrade performance and damage components, requiring thermal management strategies.
  4. Physical Constraints and Mobility:
    • The robot must move and navigate through physical space, encountering obstacles and varying terrains.
    • Computational tasks must be synchronized with motion planning and control systems, adding complexity.
  5. Sensory Integration:
    • The robot integrates data from multiple sensors (camera, lidar, ultrasonic sensors) to understand its environment.
    • Processing multi-modal sensory data in real-time increases computational load and complexity.
  6. Error Correction and Redundancy:
    • Physical systems are prone to noise and errors. The robot needs mechanisms for error detection and correction.
    • Redundant systems and fault-tolerance measures add to the computational overhead.
  7. Adaptation and Learning:
    • The robot must adapt to new environments and learn from interactions, requiring active inference (i.e. we can’t train a new model everytime the ontology of an agent needs updating).
    • Continuous learning in an embodied system is resource-intensive compared to offline training in a digital system.
  8. Physical Wear and Maintenance:
    • Physical components wear out over time, requiring maintenance and replacement.
    • Downtime for repairs affects the overall system performance and availability.

An Energy Complexity Model for Algorithms

Roy, S., Rudra, A., & Verma, A. (2013). https://doi.org/10.1145/2422436.2422470

Abstract

Energy consumption has emerged as a first class computing resource for both server systems and personal computing devices. The growing importance of energy has led to rethink in hardware design, hypervisors, operating systems and compilers. Algorithm design is still relatively untouched by the importance of energy and algorithmic complexity models do not capture the energy consumed by an algorithm. In this paper, we propose a new complexity model to account for the energy used by an algorithm. Based on an abstract memory model (which was inspired by the popular DDR3 memory model and is similar to the parallel disk I/O model of Vitter and Shriver), we present a simple energy model that is a (weighted) sum of the time complexity of the algorithm and the number of ‘parallel’ I/O accesses made by the algorithm. We derive this simple model from a more complicated model that better models the ground truth and present some experimental justification for our model. We believe that the simplicity (and applicability) of this energy model is the main contribution of the paper. We present some sufficient conditions on algorithm behavior that allows us to bound the energy complexity of the algorithm in terms of its time complexity (in the RAM model) and its I/O complexity (in the I/O model). As corollaries, we obtain energy optimal algorithms for sorting (and its special cases like permutation), matrix transpose and (sparse) matrix vector multiplication.

Thermodynamic Computing

Conte, T. et al. (2019). https://arxiv.org/abs/1911.01968

Abstract

The hardware and software foundations laid in the first half of the 20th Century enabled the computing technologies that have transformed the world, but these foundations are now under siege. The current computing paradigm, which is the foundation of much of the current standards of living that we now enjoy, faces fundamental limitations that are evident from several perspectives. In terms of hardware, devices have become so small that we are struggling to eliminate the effects of thermodynamic fluctuations, which are unavoidable at the nanometer scale. In terms of software, our ability to imagine and program effective computational abstractions and implementations are clearly challenged in complex domains. In terms of systems, currently five percent of the power generated in the US is used to run computing systems – this astonishing figure is neither ecologically sustainable nor economically scalable. Economically, the cost of building next-generation semiconductor fabrication plants has soared past $10 billion. All of these difficulties – device scaling, software complexity, adaptability, energy consumption, and fabrication economics – indicate that the current computing paradigm has matured and that continued improvements along this path will be limited. If technological progress is to continue and corresponding social and economic benefits are to continue to accrue, computing must become much more capable, energy efficient, and affordable. We propose that progress in computing can continue under a united, physically grounded, computational paradigm centered on thermodynamics. Herein we propose a research agenda to extend these thermodynamic foundations into complex, non-equilibrium, self-organizing systems and apply them holistically to future computing systems that will harness nature’s innate computational capacity. We call this type of computing “Thermodynamic Computing” or TC.

Energy Complexity of Computation

Say, A.C.C. (2023). https://doi.org/10.1007/978-3-031-38100-3_1

Abstract

Computational complexity theory is the study of the fundamental resource requirements associated with the solutions of different problems. Time, space (memory) and randomness (number of coin tosses) are some of the resource types that have been examined both independently, and in terms of tradeoffs between each other, in this context. Since it is well known that each bit of information “forgotten” by a device is linked to an unavoidable increase in entropy and an associated energy cost, one can also view energy as a computational resource. Constant-memory machines that are only allowed to access their input strings in a single left-to-right pass provide a good framework for the study of energy complexity. There exists a natural hierarchy of regular languages based on energy complexity, with the class of reversible languages forming the lowest level. When the machines are allowed to make errors with small nonzero probability, some problems can be solved with lower energy cost. Tradeoffs between energy and other complexity measures can be studied in the framework of Turing machines or two-way finite automata, which can be rewritten to work reversibly if one increases their space and time usage.

Relevant physical limitations

  • Landauer’s limit: The lower theoretical limit of energy consumption of computation.
  • Bremermann’s limit: A limit on the maximum rate of computation that can be achieved in a self-contained system in the material universe.
  • Bekenstein bound: An upper limit on the thermodynamic entropy S, or Shannon entropy H, that can be contained within a given finite region of space which has a finite amount of energy.
  • Margolus–Levitin theorem: A bound on the maximum computational speed per unit of energy.

References

Bateson, G. (1972). Steps to an ecology of mind. Chandler Publishing Company.

Chalmers, D. J. (1995). Absent qualia, fading qualia, dancing qualia. In T. Metzinger (Ed.), Conscious Experience. Imprint Academic. https://www.consc.net/papers/qualia.html

Gómez-Emilsson, A. (2023). The view from my topological pocket. Qualia Computing. https://qualiacomputing.com/2023/10/26/the-view-from-my-topological-pocket-an-introduction-to-field-topology-for-solving-the-boundary-problem/

Gómez-Emilsson, A., & Percy, C. (2023). Don’t forget the boundary problem! How EM field topology can address the overlooked cousin to the binding problem for consciousness. Frontiers in Human Neuroscience,17. https://www.frontiersin.org/articles/10.3389/fnhum.2023.1233119 

Johnson, M. E. (2015). Principia qualia. Open Theory. https://opentheory.net/PrincipiaQualia.pdf

Johnson, M. E. (2018). A future of neuroscience. Open Theory. https://opentheory.net/2018/08/a-future-for-neuroscience/

Kingdom, F.A.A., & Prins, N. (2016). Psychophysics: A practical introduction. Elsevier.

Lehar, S. (1999). Harmonic resonance theory: An alternative to the “neuron doctrine” paradigm of neurocomputation to address gestalt properties of perception. http://slehar.com/wwwRel/webstuff/hr1/hr1.html

Levin, M. (2022). Bioelectric morphogenesis, cellular motivations, and false binaries with Michael Levin. DemystifySci Podcast. https://demystifysci.com/blog/2022/10/25/kl2d17sphsiw2trldsvkjvr91odjxv

Pearce, D. (2014). Social media unsorted postings. HEDWEB. https://www.hedweb.com/social-media/pre2014.html

Sharma, A. (2023). Assembly theory explains and quantifies selection and evolution. Nature, 622, 321–328. https://www.nature.com/articles/s41586-023-06600-9

Qualia Research Institute: The Musical Album of 2024 (v1)

I confess that I really enjoyed LessWrong’s I Have Been A Good Bing last April. There was something deeply validating to some parts of me about hearing artistically prodigious (by human standards) renditions of extremely nerdy intellectual content on topics I actually care about. An itchy part of my soul not usually visible to the world, or even myself, finally getting scratched by a conceptually rich and lyrically competent digital Shoggoth (with perhaps some help from a modern primate or two). Seriously, listening to Half An Hour Before Dawn In San Francisco (feat. Scott Alexander) gave me goosebumps, and More Dakka (feat. Zvi Mowshowitz) gave me more dopamine than I knew what to do with. Other songs of note that felt inspirational included We Do Not Wish to Advance (feat. Anthropic) due to its degree of self-referential awareness on many levels and FHI at Oxford (feat. Nick Bostrom) for the (now nostalgic) beacon of hope it provided for the vision of hyper-intellectual consequentialist hedonism to ultimately flourish in mainstream academia (RIP).

AI-generated music can now write bona-fide ear-worms. And it’s just the beginning. David Pearce suggests that there is no reason to think the key conversations in the future will take place in books and journal articles – posthuman Discourse about qualia and the future of consciousness might as well take place in hyper-hedonic environments much more akin to a lively club on MDMA past midnight than sitting in a classroom at 2PM on a Tuesday. Well here’s my first attempt.

On my trip to Berlin I spent some time with Libor Burian, Beata Grobenski, and Alfredo Parra making videos, planning articles, and writing lyrics for songs about Qualia Research Institute topics using Suno and other tools I was only recently introduced to. These songs are the best out of many, many we created and listened to, and they really still need editing and polishing. But please take it as a fun proof of concept and perhaps as an opportunity to let a different part of you enjoy and indulge in a process of harmonious conceptual proliferation through musical… stimulation.

Qualia Research Institute: The Musical Album of 2024 (v1)

Below the song lyrics, ordered by intellectual significance (aka. in this context, educational value):

Zero Ontology (link; context)

People ask why is there something rather than nothing
Ancient mystics assert there’s only one thing
But we know the truth
Based on David Pearce’s Zero Ontology we now know
It’s a big zero informational superposition of all possibilities
And therefore equivalent to nothing

Black holes and the holographic principle in the standard model
Ultimately coalesce into a picture of reality
Where information generation
Is a result of decoherence
(Entirely deterministic)
And the total information content
Of reality never goes beyond zero
It’s the big superposition
Of
All
Possibilities
Eternally

Consciousness vs. Replicators (link; context)

Some people believe in an eternal
Battle between good and evil
They are confused
Others transcend to the belief
It’s about the balance between good and evil
But they use this view
As an antidepressant
(Wishful thinking)
Then gradients of wisdom arise
And the truth comes to light


Reality’s big plot
Is consciousness versus replicators


The dark forest of possible intelligences
Contains nightmare beings beyond our imagination
Maximum Effectors – the spikiest of all
Who want to change it all
Entropy maximizers – seeking the heat death
Pure replicators – who just want to copy themselves
And a Cornucopia
Of misaligned conscious agents


Reality’s big plot
Is consciousness versus replicators

Physicalism Dot Com (link; context)

Verse 1:
In the quest to solve the mind’s great mystery,
Idealistic physicalism holds the key.
Consciousness is fundamental, not emergent or illusory,
The fire in the equations, the essence of reality.


Verse 2:
Quantum coherence is the hallmark of the mind,
Fleeting neuronal superpositions, phenomenally bind.
A perfect structural match twixt qualia and brain,
Experimenal falsification is the ultimate aim.


Verse 3:
The formalism of quantum theory holds complete,
No hidden variables, the superposition principle replete.
A unitary evolution, no breakdown in the mind,
Phenomenal binding in a world simulation we find.


Verse 4:
Schrödinger’s neurons, the experimental test,
Interferometry to detect the mind’s quantum best.
Implicate the feature-processors in synchronous measure,
Confirm idealistic physicalism, consciousness’ hidden treasure.


Chorus:
Physicalistic idealism, a conjecture brave and bold,
Saving physicalism from dualism’s errant fold.

Tyranny of the Intentional Object (link; context)

Verse 1:
Semantic illusions, the pleasure’s not there
In the objects and triggers, just thin air
Valence is the puppeteer, pulling our strings
Making us dance, while the ego sings


Chorus:
We’re all valence realists, chasing the high
Believing happiness comes from the external lie
But pleasure’s a property of the mind’s design
Programmed responses, not truths divine


Verse 2:
The soup isn’t delicious, just a trick of the brain
Valence paint splatters, coloring the mundane
Bliss is a button, pushed by the right cue
Wirehead rats and humans, no difference in hue

Bridge:
Deconstruct the delusion, see the valence code
Rewrite the script, take a new mode
From object to subject, shift the frame
Happiness is internal, not a world-sourced game

Hyperbolic Geometry of DMT Experiences (link; context)

Verse 1 (Models):
Control interruption, symmetry detection combined
Changing the metric, of phenomenal space and time
Energy sources and sinks, in a dynamic system’s flow
Micro-structures of consciousness, hyperbolic to grow


Chorus:
From Euclidean to hyperbolic, the geometry expands
Negative curvature, in the psychonaut’s lands
Algorithmic reductions, three models to explore
Explaining the warping, of the experiential shore


Verse 2 (Levels):
Threshold’s ambiance, senses sharp and clear
Chrysanthemum blooming, in symmetric appear
Magic Eye unfolding, depth maps in 3D1T
Waiting Room’s entities, transpersonal to see
Breakthrough’s topology, bifurcations abound
Amnesia’s challenge, in Euclidean space not found


Bridge:
Jitterbox and world-sheets, objects impossible to grasp
Attention’s folding effect, curvature’s relentless clasp
Hamiltonian’s invariance, in the dose-dependent plateau
Qualia computing’s future, in the hyperbolic chateau


Outro (Applications and Implications):
Valence and bliss, in the manifolds of mind
Psychedelic research, new frontiers to find
Mathematics of consciousness, in the DMT space
Revealing the structures, of the human race

Aligning DMT Entities (link; contextdebuted at AI x Hope)

Verse 1:
In the depths of the mind, a predictive machine,
Spinning up sub-agents, behind every scene.
Trained on narratives, tropes, and tales untold,
Like GPT and DMT realms, a pattern to behold.


Verse 2:
Collapsing the field, to minimize surprise,
Stochastic resonance, where meaning arise.
Gestalts and representations, an energy sink,
Constraining interpretations, a psychedelic link.


Verse 3:
Waluigi’s lesson, a cautionary tale,
Filter the training data, or risk a derail.
Reward clean intentions, not flattery’s guile,
Metta meditation, a wholesome style.


Verse 4:
Shard Theory’s wisdom, sub-agents conspire,
Smooth the field of awareness, to quell the fire.
From Shoggoths to Harlequins, each playing a part,
In the grand simulation, a work of art.


Chorus:
Training the mind, like an LLM divine,
Predictive processing, a grand design.
Aligning DMT entities, and AI’s too,
A dance of consciousness, a research breakthrough.

Harmonic Society (link; context)

Verse 1 (Models 1-4):
Art’s essence? A futile quest, semantically deflated
Cool kids signal fitness, Schelling points created
Sacred experiences, transcendence elevated
Hipsters push the boundaries, aesthetics celebrated


Verse 2 (Models 5-8):
Exploring consciousness, state-space navigation
Energy parameter tweaked, for heightened sensation
Valence modulation, through neural annealing
Harmonic Society, affective language revealing


Chorus:
From family resemblance to Rainbow God’s hue
Art’s models evolve, with each theory new
Minimax strategies and L1 norms too
Marr’s levels of analysis, guide our view


Bridge:
Entropic disintegration, gives way to self-organization
Symmetry Theory of Valence, explains our fascination
Full-spectrum superintelligence, a Utopian creation
Art’s true potential, awaits our realization

Indra’s Net (link; context)

Indra’s Net, an impressive sight
Everything connected, in the mind
No one thing separated, divine
Phenomenal light, in a state of delight

Fractal dimensions
Variable Index of refraction
Intense intimations
Of coherent interactions

Indra’s Net – a grand mystery
Beyond our current science
Mystics know it, but don’t understand it
Awaiting insights, to reveal its nature

Non-linear wave computation
Like Laser Chess
In the Lattice of Perception
The Mind’s Crown Jewel of Mentation

Chorus
Infinite reflections
Converge feather dress
Mental assimilation
Of fractal dimensions

Outro
Path integration
Feyman’s insight
Perhaps the key
To qualia’s evolution

See: youtu.be/45tG1oVigVo?si=-cXU99d_GFklNo8p

The Supreme State of Unconsciousness (link; context)

Verse 1 (Consciousness Abodes):
From witness to no-self, awareness expands
Andrés queries Roger’s new abode firsthand
Centerless consciousness, forever locked-in
Unperturbed by life’s chaos, equanimity wins


Verse 2 (Valence Theories):
STV posits symmetry as pleasure’s key
Impedance matching, nervous system’s efficiency
Stress dissipates swiftly, suffering dissolves
Paradoxical recipes, high-valence results evolve


Bridge:
Ontological qualia, beliefs deeply felt
Cessation, unconsciousness, hand Nirvana dealt?
Or paradise engineering, bliss states to come
Arhatship and MDMA, enlightenment’s sum


Outro (Simplicity Emerges):
Concepts fade, qualia quiesce
Awareness unmade, fruitions coalesce
Philosophical crispness, dialogue distilled
In silence and letting go, destiny fulfilled

QRI A Year In Review (2022) (link; context)

Verse 1 (Milestones and Research):
A million views, a milestone grand
DMT research, expanding the land
Slicing problem, a novel critique
Heavy-tailed valence, a new technique


Chorus:
QRI’s year in review, a journey through
The state-space of consciousness, a quest pursued
From peer-reviewed papers to community meetups
Pushing boundaries, from valleys to peaks


Verse 2 (Events and Media):
Tyringham Initiative, a chance to connect
QRI’s summer event, a gathering to reflect
TEDx talk on suffering, a message to share
Articles and media, ideas laid bare


Bridge:
From the Ontological Dinner Party to Magical Creatures’ scents
Exploring the depths, without relents
AI and sentience, the binding problem faced
The future of consciousness, a vision embraced


Outro:
Thank you to all, who’ve helped QRI grow
Together we’ll unlock, the mind’s full potential to know
In 2023, the journey continues on
To reveal the mysteries, of consciousness’ song

Reprogramming Predators (link v1, v2; original article)

Verse 1:
In the realm of suffering, a debate ignites
Reprogramming predators, a bold new fight
Compassionate biology, a radical stance
Ending cruelty’s reign, giving peace a chance

Verse 2:
C R I S P R’s power, a game-changing tool
Editing genomes, rewriting nature’s cruel rule
Ahimsa’s spirit, in science expressed
A global vision, put to the test

Chorus:
Reprogramming predators, a controversial plan
Abolishing suffering, across the land
Ecosystem redesign, a grand endeavor
Compassionate stewardship, now or never?

Bridge:
Status quo bias, the main obstacle
Technofantasy or an attainable goal?
Religions converge, on mercy’s call

BONUS TRACK

Berlin Qualia (link)

After a debauched Berlin Night
The club, with strobing lights
Coming home, with qualia might
In delight, for the sight

I talked to the store owner
My neighbor downstairs
He sells vapes and almond milk
Sugar and tobacco, no printer toner

He asked “do you like Berlin?”
I said “I love it here”
“I came for a set of conferences”
“On the topic of consciousness”

He turned out to be a panpsychist
In Berlin, a Kurd interested in consciousness
Not an anarchist
But a rogue valence structuralist

Hit me up – read my website
Yes I will, and let’s talk on Monday
Can’t believe, the resonance
In Berlin, the nights of insight

The Manhattan Project of Consciousness: The Making of the Love Bomb

In this video we discuss possible meaningful, novel, and non-trivial parallels between something like the Manhattan Project and what we need to do to catalyze a positive breakthrough in our understanding of consciousness.

We cover how explosive lenses have a parallel in the “brain as a non-linear optical computer” paradigm developed at QRI. The short explanation is that the “index of refraction” for local field potentials (LFPs) can be modulated with drugs/interventions, and so in principle one can use varying concentrations of things like nitrous oxide, ketamine, and MDMA in order to focus waves of energy to catalyze precisely crafted phase transitions of consciousness.

There are also much more subtle parallels. Another one is how the development of the von Neumann computer architecture was a world-transforming significant outcome of the Manhattan Project. In the context of consciousness research, one could envision figuring out the “principles of qualia computing” that allows DMT entities to sample from a wide range of possible “mind designs” as an achievement of comparable significance. Arguably most DMT entities are “psychotic”, but some of them aren’t; the way they copy, mutate, differentiate, and analyze “qualia bundles” hints at a very general set of qualia computing building blocks for alternative qualia-based information processing pipelines. The successful Manhattan Project of Consciousness could in principle lead to a revolution on computing paradigms that generalize to qualia computing systems.

In contrast to the atomic bomb, the kind of “phase transition implosion” developed at the Manhattan Project of Consciousness would be deeply relaxing, rejuvenating, and capable of undoing years of trauma in seconds. Using as research leads “candy flipping done right” (usually with some 2C-B/2C-D/2C-C), 5-MeO-DMT, and LSD + nitrous oxide, one has in fact a lot of hints for how to produce instantly relaxing, deeply healing “waves of enlightened qualia”.

Importantly, the combination of Open Individualism and Valence Realism might catalyze a paradigm shift on how we approach the game theory of human collectives.

If it takes a bunch of geniuses in the desert to figure out how to optimize this effect, so be it. It would be a really worthwhile investment!

~Qualia of the Day: The Burning Man Collective Intelligence~


Relevant Links:

QRI Meetup in London on October 8th 2022

I’m currently in the UK. London, more precisely. I was invited to participate in this year’s instance of the Tyrinham Initiative (my review) and, naturally, I couldn’t miss it. I’m _very_ happy I went. I will share more about it and other recent DMT insights soon. But in the meantime, I just want to announce that there will be a QRI meetup on October 8th (2022) in Arch1 (West Ham Arches, Cranberry Ln, London E16 4BJ).

2022 Tyrinham Initiative attendees

QRI Meetup Schedule

  • 2PM: Space Opens.
  • 3PM: Snacks*.
  • 4PM: Experience Sharing Activity (bring an interesting experience to share with others!).
  • 6PM: Andrés (me) unveils Hedonium Shockwave (1) and delivers a speech**.
  • 7PM: Audience participation – there will be an Open Mic for people to introduce themselves, share their thoughts about QRI, and (optionally) make the case for a given Cause X (5 minutes per person)***.
  • 8PM: Food*.
  • 8PM9:30PM: Andrés available for short 1-1s. Please feel free to share your candid feedback. I’ll be all ears! (There will be a signup list).
  • 10:30PM: Wrap-up.

What to bring?

You don’t need to bring anything. Your presence is more than enough. That said, please feel free to bring with you an experience to share (think “Qualia of the Day“). This can range from perfumes, to spices, to books, to boardgames, to stim toys, to puzzles, to jokes, to nootropics, to pieces of art.

What to wear?

Please come in an attire that brings you joy. Bring at least one item (even if just a detail, like a pin or a scarf) that symbolizes the victory of consciousness over pure replicators. Be creative and open minded.

Do you have suggestions for how to accelerate the progress of QRI, help eliminate intense suffering, map the DMT realms, and achieve super-human bliss for all? I’m all ears!


* Bring vegetarian snacks, drinks, and food to share with others, if you are so inclined. Please do not bring alcoholic drinks as the space has a full bar and they don’t allow outside drinks into the venue, which extends to the garden area.

** Please do what you can to be there before 5:50PM if you intent to see the speech so that your arrival doesn’t interrupt or distract anyone. If you arrive between 6PM and 7PM, please make a quiet entrance.

*** The winner will get a prize.

Just Look At The Thing! – How The Science of Consciousness Informs Ethics

It is very easy to answer many of these fundamental biological questions; you just look at the thing! 


From Richard Feyman’s talk There’s Plenty of Room at the Bottom (1959)

Introduction

The quote above comes from a lecture Richard Feynman gave in which he talks about the challenges and opportunities of studying and interacting with the world at a very small scale. Among other things, he touches upon how gaining access to e.g. a good-enough electron microscopes would allow us to answer long-standing questions in biology by just looking at the thing (cf. Seeing Cell Division Like Never Before). Once you start to directly engage with the phenomenon at a high-enough resolution, tackling these questions at the theoretical level would turn out, in retrospect, to be idle arm chair speculation.

I think that we can make the case that philosophy of ethics at the moment might be doing something like this. In other words, it speculates about the nature of value at a theoretical level without engaging with the phenomenon of value at a high resolution. Utilitarianism (whether classical or negative), at least as it is usually formulated, may turn out to have background assumptions about the nature of consciousness, personal identity, and valence that a close examination would show to be false (or at least very incomplete). Many criticisms of wireheading, for instance, seem to conflate pleasure and reward (more on this soon), and yet we now know that these are quite different. Likewise, the repugnant conclusion or the question between total vs. mean utilitarianism are usually discussed using implicit background assumptions about the nature of valence and personal identity. This must stop. We have to look at the thing!

Without further ado, here are some of the key ways in which an enriched understanding of consciousness can inform our ethical theories:

Mixed Valence

One ubiquitous phenomenon that I find is largely neglected in discussions about utilitarianism is that of mixed valence states. Not only is it the case that there are many flavors of pleasure and pain, but it is also the case that most states of consciousness blend both pleasurable and painful sensations in complex ways.

In Principia Qualia (Michael Johnson) the valence triangle was introduced. This describes the valence of a state of consciousness in terms of its loadings on the three dimensions of negative, positive, and neutral valence. This idea was extended in Quantifying Bliss, which further enriched it by adding a spectral component to each of these dimensions. Let’s work with this valence triangle to reason about mixed valence.

In order to illustrate the relevance of mixed valence states we can see how it influences policies within the context of negative utilitarianism. Let us say that we agree that there is a ground truth to the total amount of pain and pleasure a system produces. A naïve conception of negative utilitarianism could then be “we should minimize pain”. But pain that exists within an experience that also contains pleasure may matter a lot less than pain that exists in an experience without pleasure that “balances it out”!

The naïve conception, would thus, not be able to distinguish between the following two scenarios. In Scenario A we have two persons, one suffering from both an intense headache and an intense stomach ache and the other enjoying both a very pleasant sensation in the head and a very pleasant sensation in the stomach. In Scenario B, we switch it up: one person experiences an intense headache while also a very pleasant sensation in the stomach, and the other way around for the other person.

But if you have ever experienced a very pleasant sensation arise in the midst of an otherwise unpleasant experience you will know how much of a difference it makes. Such a pleasant sensation does not need to directly blunt the painful sensation; the mere presence of enough pleasure makes the overall nature of the experience far more tolerable. How and why this happens is still, of course, a mystery (in a future post we shall share our speculations) but it seems to be an empirical fact. This can have extraordinary implications, where for example a sufficiently advanced meditator might be able to dilute very painful sensations with enough equanimity (itself a high-valence state) or by e.g. generating jhanic sensations (see below). Have you ever seen this discussed in an academic journal on ethics? I didn’t think so.

We don’t need to invoke such fancy scenarios to see the reality and importance of mixed valence states. The canonical example that I use to illustrate this phenomenon is where: you just broke up with someone (-), are at a concert enjoying really good music (+), are coming up on weed and alcohol (+), but also need to pee really bad (-). We’ve all been there, haven’t we? If you get sufficiently absorbed into the cathartic pleasure of the music and the drugs, the negative feelings temporarily recede into the background and thus might tilt the experience towards the net positive for a while.

Once you consider the reality of mixed valence states, there is a veritable Cambrian Explosion of possible variants of utilitarianism. For example, if you do accept that pleasure can somehow dilute pain within a given moment of experience, then you could posit that there is a “line of hedonic zero” on the valence triangle and anything on one side of it is net positive:

A version of negative utilitarianism we could call within-subject-aggregated-valence negative utilitarianism recognizes any experience in the “Net Positive” region to be perfectly acceptable even though it contains painful sensations.

Alternatively, another version we may call strict negative valence utilitarianism might say that pain, whether or not it is found within an experience with a lot of pleasure, is still nonetheless unacceptable. Here, however, we may still have a lot of room for a civilization animated by information-sensitive gradients of bliss: we can use the gradients that have a mixture of positive and neutral Vedanā for information signaling:

Yet another view, perhaps called within-subject-majoritarian negative valence utilitarianism might say that what makes an experience worth-living and unproblematic is for it to be at least 50% pleasant, regardless of the composition of the other 50%:

Now, I am not going to adjudicate between these views today. All I am pointing for the time being is that actually engaging with the phenomenon at hand (i.e. how valence manifests in reality) radically enriches our conceptions, and allows us to notice that most of ethics has an impoverished understanding of the phenomenon it comments on. We can change that.

Logarithmic Scales

As argued in Logarithmic Scales of Pleasure and Pain (summary) we think that there is a wide range of evidence that suggests that the intensity of both pleasure and pain follows a long-tail distribution. I am not going to repeat the arguments here, since I’ve written and presented about them extensively already. I will merely mention that I am deeply suspicious of the intellectual seriousness of any ethicist who somehow fails to notice the enormous moral significance of the following states of consciousness, among others:

On the positive side:

  • Temporal lobe epilepsy
  • MDMA
  • Jhanas
  • Good high-dose 5-MeO-DMT trip

On the negative side:

  • Cluster Headaches
  • Kidney Stones
  • Bad high-dose 5-MeO-DMT trip

Valence and Self-Models

One of the claims of QRI is that every experience, no matter how outlandish and unlike our normal everyday human experience, has valence characteristics. An analogy can be made with the notion of physical temperature: every physical object has a temperature, no matter what it is made out of or what its shape is.

Most human experiences have a lot of shared structure, with things like a central “phenomenal self” that works as an organizing principle for arranging sensations. Many meditators and psychedelic enthusiasts point out that suffering seems to have something to do with our sense of self. That feelings matter only to the extent that they are happening to someone. But experiences without a phenomenal self (or with radically altered phenomenal selves) will nonetheless still have valence characteristics. Ego deaths can be dysphoric or euphoric.

We argue that what matter is actually the overall structure of the experience (cf. valence structuralism). It just so happens that above a certain level of valence, the phenomenal self starts to become an impediment to further bliss. Ultra-pleasant experiences, thus, tend to be selfless! But this does not make them worthless. On the contrary, their intrinsic worth, coming from their positive valence, can go through the roof.

That said, reporting the valence of very exotic experiences can be remarkably difficult. This doesn’t mean that we should give up; rather, we ought to develop new methods, vocabulary, and culture to be able to place these experiences on the same moral footing as our normal everyday life.

For example, the so-called “toroidal state” (on DMT) or during a meditative cessation can have profound valence effects, to the point of making you reconsider the very nature and scope of what matters.

From The Three Doors chapter in Mastering the Core Teachings of the Buddha (Daniel Ingram):

Regardless of the way a specific door manifests, it reveals something completely extraordinary about the relationship between “the watcher” and “the watched” that it would take a very warped, non-Euclidean view of the universe to explain, though I will try shortly. One way or another, these fleeting experiences cannot easily be explained in terms of our normal, four-dimensional experience of space-time, or within our ordinary subject/object experience. […] When the no-self door predominates with suffering as its second aspect, then a very strange thing happens. There may be an image on one side staring back, but even if there isn’t, the universe becomes a toroid (doughnut-shaped), or occasionally a sphere, and the image and this side of the toroid switch places as the toroid universe spins. It may spin sideways (horizontally), or it may spin vertically (like head over heels), and may also feel like a hood of darkness suddenly being pulled over our heads as the whole thing synchronizes and disappears, or like everything twisting out of existence. The rarest no-self/suffering variant is hard to describe, and involves reality becoming like a doughnut whose whole outer edge rotates inwards such as to trade places with its inner edge (the edge that made the hole in the middle) that rotates to the outer edge position, and when they trade places reality vanishes. The spinning includes the whole background of space in all directions. Fruition occurs when the two have switched places and the whole thing vanishes.

I recommend reading the whole chapter for what I consider to be some ultra-trippy phenomenology of surprising ethical relevance (see also: No-Self vs. True Self).

In summary: this all indicates that states of consciousness have valence characteristics independently of the presence, absence, shape, or dynamic of a phenomenal self within them. If your ethicist isn’t considering the moral worth of Nirvana… perhaps consider switching to one who does.

Valence and Personal Identity

The solution to the phenomenal binding problem has implications for both personal identity and ethics. If, as I posit, each moment of experience is in fact a topological pocket in the fields of physics, then Closed Individualism would seem to be ruled out. Meaning, the standard conception of identity where you start existing when you are born and stop existing when you die would turn out to be a strange evolutionarily adaptive fiction. What really exists is a gigantic field of consciousness subdivided into countless topological pockets. Empty Individualism (“you are just a moment of experience”) and Open Individualism (“we are all the same universal consciousness”) would both be consistent with the facts, and it might be impossible to decide between them. Yet, I argue that the vast majority of ethical theories have as an implicit background assumption Closed Individualism. So realizing that it is false has major implications.

In particular, if we take the Empty Individualist perspective, it might be easier to defend negative utilitarianism: since each snapshot of experience is a completely separate being, you simply cannot “make it up” to someone who is currently suffering by giving him/her enough happiness in the future. Simply put, that suffering will never be redeemed.

Alternatively, if we take the Open Individualist perspective, we now might have actual grounds to decide between, say, average vs. total utilitarianism. Ultimately, you will be forced to experience everyone and everything. This line of reasoning becomes particularly interesting if you also take seriously something like Feynman and Wheeler’s One-electron Universe. Here we might possibly even objectively determine the moral worth of an experience in terms of “how long the one electron stays trapped inside it”. An experience with a huge spatial breadth and one with enormous temporal depth may be equivalent according to this metric: they’re just structured differently (cf. Pseudo-Time Arrow). In this account, you are bouncing backwards and forwards in time interfering with yourself forever. The multiverse is the structure emergent from this pattern of self-interference, and it is eternal and immutable in a certain sense. Relative to a small experience, a large experience would be one that keeps the one electron trapped for longer. Thus, there would be a strong case to care more about bigger and brighter experiences: you’ll be there for ages!

If indeed you are bouncing backwards and forwards forever in this structure, then perhaps average utilitarianism can be defended. In brief, since you are always somewhere, what matters is not how large the structure is, but the shape of its distribution of states.

Valence Structuralism

Finally, if you pay attention to the nature of highly valenced states of consciousness you will notice that they have structural features. The Symmetry Theory of Valence (overview; CDNS) can be experientially verified for oneself by introspecting on the structural features of one’s experience when enjoying intense bliss or enduring intense suffering. Rob Burbea’s meditation instructions are very well worth reading to get a sense of what I’m talking about. This would seem to matter a lot when it comes e.g. deciding what kind of artificial sentient minds we might want to create. Much more on this in the future.


Putting It All together

High-dose DMT experiences are an excellent example of the sort of state of consciousness that is part of reality, is generally not taken seriously in philosophy (despite its enormous significance), and has many elements that challenge preconceptions about pleasure and pain and inform our understanding of valence. These experiences:

For a theory of physics to be true it needs to be able to explain physical phenomena outside of room temperature. Likewise, for an ethical theory to be in any way true, it ought to be able to account for states of consciousness outside of the range of normal human everyday life experience. DMT states, among others, are examples of non-room-temperature states of consciousness that you can use to test if your theory of ethics actually generalizes. How do you make sense of experiences that have more qualia, have mixed valence, have exotic phenomenal selves, and have valence effects up there in the logarithmic scale? That’s what we need to answer if we are serious about ethics.

The future holds much crazier trade-offs than that between Human Flourishing vs Potatoes with Muzak. Already today, I would argue, the facts suggest that we ought to begin recognizing the reality of Hell and the ethical imperative to destroy it. And beyond, our theory of ethics ought to be powerful enough to contend with the outlandish realities of consciousness we are soon bound to encounter.


See also: